-
3
-
-
0019996893
-
Distribution and covalent interactions of (1-14C)acrylonitrile in the rat
-
Ahmed AE, Farooqui MYH, Upreti RK, El-Shabrawy O. 1982. Distribution and covalent interactions of (1-14C)acrylonitrile in the rat. Toxicology 23:159-175.
-
(1982)
Toxicology
, vol.23
, pp. 159-175
-
-
Ahmed, A.E.1
Farooqui, M.Y.H.2
Upreti, R.K.3
El-Shabrawy, O.4
-
4
-
-
0020595888
-
Comparative toxicokinetics of 2,3-14C- and 1-14C-acrylonitrile in the rat
-
as cited in EU, 2004
-
Ahmed AE, Farooqui MYH, Upreti RK, El-Shabrawy O. 1983. Comparative toxicokinetics of 2,3-14C- and 1-14C-acrylonitrile in the rat. J Appl Toxicol 3:39-47 (as cited in EU, 2004).
-
(1983)
J Appl Toxicol
, vol.3
, pp. 39-47
-
-
Ahmed, A.E.1
Farooqui, M.Y.H.2
Upreti, R.K.3
El-Shabrawy, O.4
-
5
-
-
0018391123
-
Studies on the metabolism of aliphatic nitriles
-
(abstract) (as cited in EU, 2004)
-
Ahmed AE, Patel K. 1979. Studies on the metabolism of aliphatic nitriles. Toxicol Appl Pharmacol 48:A91 (abstract) (as cited in EU, 2004).
-
(1979)
Toxicol Appl Pharmacol
, vol.48
-
-
Ahmed, A.E.1
Patel, K.2
-
6
-
-
0019406020
-
Acrylonitrile: In vivo metabolism in rats and mice
-
Ahmed AE, Patel K 1981 Acrylonitrile: In vivo metabolism in rats and mice. Drug Metab Dispos 9:219-222
-
(1981)
Drug Metab Dispos
, vol.9
, pp. 219-222
-
-
Ahmed, A.E.1
Patel, K.2
-
8
-
-
0019812342
-
Effect of potential antidotes on the acute toxicity of acrylonitrile
-
Appel KE, Peter H, Bolt HM. 1981a. Effect of potential antidotes on the acute toxicity of acrylonitrile. Int Arch Occup Environ Health 49:157-163
-
(1981)
Int Arch Occup Environ Health
, vol.49
, pp. 157-163
-
-
Appel, K.E.1
Peter, H.2
Bolt, H.M.3
-
9
-
-
0019364555
-
Interaction of acrylonitrile with hepatic microsomes of rats and men
-
Appel KE, Peter H, Bolt M, Bolt HM. 1981b. Interaction of acrylonitrile with hepatic microsomes of rats and men. Toxicol Lett 7:335-340
-
(1981)
Toxicol Lett
, vol.7
, pp. 335-340
-
-
Appel, K.E.1
Peter, H.2
Bolt, M.3
Bolt, H.M.4
-
10
-
-
76549092708
-
-
ATSDR (Agency for Toxic Substances and Disease Registry). Atlanta, GA: US Department of Health and Human Services Public Health Service
-
ATSDR (Agency for Toxic Substances and Disease Registry). 1991. Toxicological Profile for Acrylonitrile. Atlanta, GA: US Department of Health and Human Services Public Health Service.
-
(1991)
Toxicological Profile for Acrylonitrile
-
-
-
11
-
-
0343409414
-
Clinical symptoms of chronic poisoning by acrylonitrile
-
as cited in WHO IPCS, 1983
-
Babonov GP, Kljucikov VN, Karajeva ZV. 1959. Clinical symptoms of chronic poisoning by acrylonitrile. Vrach Delo 8:833-836 (as cited in WHO IPCS, 1983).
-
(1959)
Vrach Delo
, vol.8
, pp. 833-836
-
-
Babonov, G.P.1
Kljucikov, V.N.2
Karajeva, Z.V.3
-
12
-
-
32644436546
-
Follow-up biomonitoring after accidental exposure to acrylonitrile- Implications for protein adducts as a dose monitor for short-term exposure
-
Bader M, Wrbitzky R. 2006. Follow-up biomonitoring after accidental exposure to acrylonitrile-Implications for protein adducts as a dose monitor for short-term exposure. Toxicol Lett 162:125-131
-
(2006)
Toxicol Lett
, vol.162
, pp. 125-131
-
-
Bader, M.1
Wrbitzky, R.2
-
13
-
-
0014775734
-
Effects on rats of compounds related to acrylamide
-
Barnes JM. 1970. Effects on rats of compounds related to acrylamide. Br J Ind Med 27:147-149
-
(1970)
Br J Ind Med
, vol.27
, pp. 147-149
-
-
Barnes, J.M.1
-
14
-
-
0003844207
-
-
Washington, DC: Chemical Manufacturers Association. LB1 Project No 2660, February (as cited in ATSDR, 1991)
-
Beliles RP, Paulin HJ, Makris NG, et al. 1980. Three-generation reproduction study of rats receiving acrylonitrile in drinking water. Washington, DC: Chemical Manufacturers Association. LB1 Project No 2660, February (as cited in ATSDR, 1991).
-
(1980)
Three-generation Reproduction Study of Rats Receiving Acrylonitrile in Drinking Water
-
-
Beliles, R.P.1
Paulin, H.J.2
Makris, N.G.3
-
15
-
-
0031869770
-
Mortality of United Kingdom acrylonitrile workers- An extended and updated study
-
Benn T, Osborne K. 1998. Mortality of United Kingdom acrylonitrile workers- An extended and updated study. Scand J Work Environ Health (24 Suppl) 2:17-24
-
(1998)
Scand J Work Environ Health
, vol.2
, Issue.24 SUPPL.
, pp. 17-24
-
-
Benn, T.1
Osborne, K.2
-
16
-
-
26944496763
-
Effect of cytochrome P450 inhibitors and anticonvulsants on the acute toxicity of acrylonitrile
-
Benz FW, Nerland DE. 2005. Effect of cytochrome P450 inhibitors and anticonvulsants on the acute toxicity of acrylonitrile. Arch Toxicol 79:610-614
-
(2005)
Arch Toxicol
, vol.79
, pp. 610-614
-
-
Benz, F.W.1
Nerland, D.E.2
-
17
-
-
0031023980
-
Hemoglobin adducts of acrylamide and acrylonitrile in laboratory workers smokers and nonsmokers
-
Bergmark E. 1997. Hemoglobin adducts of acrylamide and acrylonitrile in laboratory workers smokers and nonsmokers. Chem Res Toxicol 10:78-84
-
(1997)
Chem Res Toxicol
, vol.10
, pp. 78-84
-
-
Bergmark, E.1
-
19
-
-
0022641697
-
Primary brain tumors in Fischer 344 rats chronically exposed to acrylonitrile in their drinking water
-
Bigner DD, Bigner SH, Burger PC, Shelburne JD, Friedman HS. 1986. Primary brain tumors in Fischer 344 rats chronically exposed to acrylonitrile in their drinking water. Food Chem Toxicol 24:129-137
-
(1986)
Food Chem Toxicol
, vol.24
, pp. 129-137
-
-
Bigner, D.D.1
Bigner, S.H.2
Burger, P.C.3
Shelburne, J.D.4
Friedman, H.S.5
-
23
-
-
0031818618
-
Mortality of industrial workers exposed to acrylonitrile
-
Blair A, Stewart PA, Zaebst D, Pottern L, Zey J, Bloom T, Miller B, Ward Lubin J. 1998. Mortality study of industrial workers exposed to acrylonitrile. Scand J Work Environ Health (24 Suppl) 2:25-41 (as cited in EU, 2004). (Pubitemid 28377150)
-
(1998)
Scandinavian Journal of Work, Environment and Health
, vol.24
, Issue.SUPPL. 2
, pp. 25-41
-
-
Blair, A.1
Stewart, P.A.2
Zaebst, D.D.3
Pottern, L.4
Zey, J.N.5
Bloom, T.F.6
Miller, B.7
Ward, E.8
Lubin, J.9
-
24
-
-
38949133743
-
IPCS framework for analyzing the relevance of a noncancer mode of action for humans
-
Boobis Meek AR, Doe JE, Heinrich-Hirsch ME, Munn I S, Ruchirawat M, Schlatter J, Seed J, Vickers C. 2008. IPCS framework for analyzing the relevance of a noncancer mode of action for humans. Crit Rev Toxicol 38: 87-97
-
(2008)
Crit Rev Toxicol
, vol.38
, pp. 87-97
-
-
Boobis Meek, A.R.1
Doe, J.E.2
Heinrich-Hirsch, M.E.3
Munn, I.S.4
Ruchirawat, M.5
Schlatter, J.6
Seed, J.7
Vickers, C.8
-
25
-
-
0030512307
-
Evaluation of some biomonitoring markers in occupationally exposed populations to acrylonitrile
-
as cited in US EPA, 2007
-
Borba H, Monteiro M, Proenca MJ, Chaveca T, Pereira V, Lynce N, Rueff J. 1996. Evaluation of some biomonitoring markers in occupationally exposed populations to acrylonitrile. Teratogen Carcinogen Mutagen 16:205-218 (as cited in US EPA, 2007).
-
(1996)
Teratogen Carcinogen Mutagen
, vol.16
, pp. 205-218
-
-
Borba, H.1
Monteiro, M.2
Proenca, M.J.3
Chaveca, T.4
Pereira, V.5
Lynce, N.6
Rueff, J.7
-
26
-
-
0021717712
-
Clinical toxicology of acrylonitrile
-
Buchter A, Peter H. 1984. Clinical toxicology of acrylonitrile. G Ital Med Lav 6:83-86
-
(1984)
G Ital Med Lav
, vol.6
, pp. 83-86
-
-
Buchter, A.1
Peter, H.2
-
27
-
-
0028046087
-
Comparative metabolism and deposition of acrylonitrile and methacrylonitrile in rats
-
Burka LT, Sanchez M, Ahmed MTS EA, Ghanayem BI. 1994. Comparative metabolism and deposition of acrylonitrile and methacrylonitrile in rats. Arch Toxicol 68:611-618
-
(1994)
Arch Toxicol
, vol.68
, pp. 611-618
-
-
Burka, L.T.1
Sanchez, M.2
Ahmed Mts, E.A.3
Ghanayem, B.I.4
-
28
-
-
0037102011
-
Acrylonitrile irreversibly inactivates glyceraldehyde-3-phosphate dehydrogenase by alkylating the catalytically active cysteine 149
-
Campian EC, Cai J, Benz FW. 2002. Acrylonitrile irreversibly inactivates glyceraldehyde-3-phosphate dehydrogenase by alkylating the catalytically active cysteine 149. Chem Biol Interact 140:279-291
-
(2002)
Chem Biol Interact
, vol.140
, pp. 279-291
-
-
Campian, E.C.1
Cai, J.2
Benz, F.W.3
-
29
-
-
0025339854
-
Acrylonitrile-induced sisterchromatid exchanges and DNA single-strand breaks in adult human bronchial epithelial cells
-
as cited in US EPA, 2007
-
Chang C-M, Hsia MTS Stoner GD, Hsu I-C. 1990. Acrylonitrile-induced sisterchromatid exchanges and DNA single-strand breaks in adult human bronchial epithelial cells. Mutat Res 241:355-360 (as cited in US EPA, 2007).
-
(1990)
Mutat Res
, vol.241
, pp. 355-360
-
-
Chang, C.-M.1
Hsia Mts Stoner, G.D.2
Hsu, I.-C.3
-
30
-
-
76549136162
-
Chem findercom database and internet searching
-
retrieved online June 5, 2007
-
ChemFinder. 2007. ChemFindercom Database and Internet Searching. Acrylonitrile. http://chemfindercambridgesoftcom/resultasp [retrieved online June 5, 2007].
-
(2007)
Acrylonitrile
-
-
-
31
-
-
0032781241
-
The diagnosis and treatment of acute acrylonitrile poisoning: A clinical study of 144 cases
-
Chen Y, Chen C, Jin S, Zhou L. 1999. The diagnosis and treatment of acute acrylonitrile poisoning: A clinical study of 144 cases. J Occup Health 41:172-176
-
(1999)
J Occup Health
, vol.41
, pp. 172-176
-
-
Chen, Y.1
Chen, C.2
Jin, S.3
Zhou, L.4
-
32
-
-
0023088709
-
Cancer incidence and mortality among workers exposed to acrylonitrile
-
as cited in ATSDR, 1991
-
Chen JL, Walrath J, O'Berg MT, et al. 1987. Cancer incidence and mortality among workers exposed to acrylonitrile. Am J Ind Med 11:157-163 (as cited in ATSDR, 1991).
-
(1987)
Am J Ind Med
, vol.11
, pp. 157-163
-
-
Chen, J.L.1
Walrath, J.2
O'Berg, M.T.3
-
33
-
-
0031847813
-
Review and meta-analysis of studies of acrylonitrile workers
-
as cited in EU, 2004
-
Collins JJ, Acquavella JF. 1998 Review and meta-analysis of studies of acrylonitrile workers. Scand J Work Environ Health (24 Suppl) 2:71-80 (as cited in EU, 2004).
-
(1998)
Scand J Work Environ Health
, vol.2
, Issue.24 SUPPL.
, pp. 71-80
-
-
Collins, J.J.1
Acquavella, J.F.2
-
34
-
-
39749107638
-
The feasibility of conducting a reproductive outcome study of Chinese acrylonitrile worker
-
Collins JJ, Cheng R, Buck GM, Zhang J, Klebanoff M, Schisterman EF, Schcffers T, Ohta H, Takaya K, Miyauchi H, Markowitz M, Divine B, Tsai S. 2003. The feasibility of conducting a reproductive outcome study of Chinese acrylonitrile worker. J Environ Occup Med 1:29-32
-
(2003)
J Environ Occup Med
, vol.1
, pp. 29-32
-
-
Collins, J.J.1
Cheng, R.2
Buck, G.M.3
Zhang, J.4
Klebanoff, M.5
Schisterman, E.F.6
Schcffers, T.7
Ohta, H.8
Takaya, K.9
Miyauchi, H.10
Markowitz, M.11
Divine, B.12
Tsai, S.13
-
35
-
-
0024571834
-
Mortality patterns among employees exposed to acrylonitrile
-
as cited in ATSDR, 1991
-
Collins JJ, Page LC, Caporossi JC, et al. 1989. Mortality patterns among employees exposed to acrylonitrile. J Occup Med 31:368-371 (as cited in ATSDR, 1991).
-
(1989)
J Occup Med
, vol.31
, pp. 368-371
-
-
Collins, J.J.1
Page, L.C.2
Caporossi, J.C.3
-
36
-
-
0001308334
-
Tests for mutagenic activity using mutation assays at two loci in the human lymphoblast cell lines TK6 and AHH-1
-
Ashby J, de Serres FJ, Draper M, Ishidate M Jr, Margolin BH, Matter BE, Shelby MD, eds. Evaluation of Short-Term Tests for Carcinogens. Report of the International Programme on Chemical Safety's Collaborative Study on In Vitro Assays, (as cited in US EPA, 2007)
-
Crespi CL, Ryan CG, Seixas GM, Turner TR, Penman BW. 1985. Tests for mutagenic activity using mutation assays at two loci in the human lymphoblast cell lines TK6 and AHH-1. In: Ashby J, de Serres FJ, Draper M, Ishidate M Jr, Margolin BH, Matter BE, Shelby MD, eds. Evaluation of Short-Term Tests for Carcinogens. Report of the International Programme on Chemical Safety's Collaborative Study on In Vitro Assays. Prog Mutat Res 5:497-516 (as cited in US EPA, 2007)
-
(1985)
Prog Mutat Res
, vol.5
, pp. 497-516
-
-
Crespi, C.L.1
Ryan, C.G.2
Seixas, G.M.3
Turner, T.R.4
Penman, B.W.5
-
37
-
-
0033045217
-
Congenital abnormalities and indicators of germinal mutations in the vicinity of an acrylonitrile producing factory
-
Czeizel AE, Hegedus S, Timar L. 1999. Congenital abnormalities and indicators of germinal mutations in the vicinity of an acrylonitrile producing factory. Mutat Res 427:105-123
-
(1999)
Mutat Res
, vol.427
, pp. 105-123
-
-
Czeizel, A.E.1
Hegedus, S.2
Timar, L.3
-
38
-
-
0024397981
-
Metabolism of organonitriles and cyanide by rat nasal tissue enzymes
-
as cited in US EPA, 2007
-
Dahl AR, Waruszewski BA. 1989. Metabolism of organonitriles and cyanide by rat nasal tissue enzymes. Xenobiotica 19:1201-1205 (as cited in US EPA, 2007).
-
(1989)
Xenobiotica
, vol.19
, pp. 1201-1205
-
-
Dahl, A.R.1
Waruszewski, B.A.2
-
39
-
-
0015771206
-
Investigation of fatal acrylonitrile intoxications. Pesticides and the environment, a continuing controversy
-
as cited in US EPA, 2007
-
Davis JH, Davies JE, Americo Rafonnelli RS, Reich G. 1973. Investigation of fatal acrylonitrile intoxications. Pesticides and the environment, a continuing controversy. Inter Med Book Corp 2:547-556 (as cited in US EPA, 2007).
-
(1973)
Inter Med Book Corp
, vol.2
, pp. 547-556
-
-
Davis, J.H.1
Davies, J.E.2
Americo Rafonnelli, R.S.3
Reich, G.4
-
40
-
-
0019974167
-
Mortality among rubber workers: VI Men with potential exposure to acrylonitrile
-
as cited in ATSDR, 1991
-
Delzell E, Monson RR. 1982. Mortality among rubber workers: VI Men with potential exposure to acrylonitrile. J Occup Med 24:767-769 (as cited in ATSDR, 1991).
-
(1982)
J Occup Med
, vol.24
, pp. 767-769
-
-
Delzell, E.1
Monson, R.R.2
-
41
-
-
0016990610
-
Gynecological morbidity and the specific functions of the female body in the chemical manufacture of "nitron"
-
as cited in US EPA, 2007
-
Dorodnova NS. 1976. Gynecological morbidity and the specific functions of the female body in the chemical manufacture of "nitron". Gig Tr Prof Zabol 8:45-46 (as cited in US EPA, 2007).
-
(1976)
Gig Tr Prof Zabol
, vol.8
, pp. 45-46
-
-
Dorodnova, N.S.1
-
42
-
-
0023083104
-
Interspecies differences in rhodanese (thiosulfate sulfurtransferase EC 2811) activity in liver kidney and plasma
-
as cited in US EPA, 2007
-
Drawbaugh RB, Marrs TC. 1987. Interspecies differences in rhodanese (thiosulfate sulfurtransferase EC 2811) activity in liver kidney and plasma. Comp Biochem Physiol 86B:307-310 (as cited in US EPA, 2007).
-
(1987)
Comp Biochem Physiol
, vol.86 B
, pp. 307-310
-
-
Drawbaugh, R.B.1
Marrs, T.C.2
-
43
-
-
76549094364
-
Acute inhalation toxicity in rats
-
Du Pont & Co. October 21, 1968
-
Du Pont & Co. 1968. Acute inhalation toxicity in rats. Haskell Laboratory Report, October 21, 1968.
-
(1968)
Haskell Laboratory Report
-
-
-
44
-
-
0002590216
-
Toxicology of acrylonitrile (vinyl cyanide). I. Study of the acute toxicity
-
Dudley HC, Neal PA. 1942. Toxicology of acrylonitrile (vinyl cyanide). I. Study of the acute toxicity. J Ind Hyg Toxicol 24:27-36
-
(1942)
J Ind Hyg Toxicol
, vol.24
, pp. 27-36
-
-
Dudley, H.C.1
Neal, P.A.2
-
45
-
-
0013616757
-
Toxicology of acrylonitrile. II. Studies of effects of daily inhalation
-
Dudley HC, Sweeney TR, Miller JW. 1942. Toxicology of acrylonitrile. II. Studies of effects of daily inhalation. J Ind Hyg Toxicol 24:255-258
-
(1942)
J Ind Hyg Toxicol
, vol.24
, pp. 255-258
-
-
Dudley, H.C.1
Sweeney, T.R.2
Miller, J.W.3
-
46
-
-
0026768321
-
Tissue-specific genotoxic effects of acrylamide and acrylonitrile
-
as cited in US EPA, 2007
-
Eldridge SR, Butterworth BE, Sprankle CS, Working PK, Bentley KS, Hurtt ME. 1992. Tissue-specific genotoxic effects of acrylamide and acrylonitrile. Environ Mol Mutagen 20:148-155 (as cited in US EPA, 2007).
-
(1992)
Environ Mol Mutagen
, vol.20
, pp. 148-155
-
-
Eldridge, S.R.1
Butterworth, B.E.2
Sprankle, C.S.3
Working, P.K.4
Bentley, K.S.5
Hurtt, M.E.6
-
47
-
-
76549111605
-
-
EU (European Union). Risk Assessment Report. Joint Research Centre Institute for Health and Consumer Protection, European Chemical Bureau EINECS No: 203
-
EU (European Union). 2004. Risk Assessment Report. Joint Research Centre Institute for Health and Consumer Protection, European Chemical Bureau. Acrylonitrile. Volume 32. EINECS No: 203:466-475
-
(2004)
Acrylonitrile
, vol.32
, pp. 466-475
-
-
-
48
-
-
0021025643
-
The effects of acrylonitrile on hemoglobin and red cell metabolism
-
Farooqui MYH, Ahmed AE. 1983a. The effects of acrylonitrile on hemoglobin and red cell metabolism. J Toxicol Envrion Health 12:695-707
-
(1983)
J Toxicol Envrion Health
, vol.12
, pp. 695-707
-
-
Farooqui, M.Y.H.1
Ahmed, A.E.2
-
49
-
-
0021087583
-
In vivo interactions of acrylonitrile with macromolecules in rats
-
Farooqui MYH, Ahmed AE. 1983b. In vivo interactions of acrylonitrile with macromolecules in rats. Chem Biol Interact 47:363-371
-
(1983)
Chem Biol Interact
, vol.47
, pp. 363-371
-
-
Farooqui, M.Y.H.1
Ahmed, A.E.2
-
50
-
-
0042382876
-
Acrylonitrile produces transient cochlear function loss and potentiates permanent noise-induced hearing loss
-
Fechter LD, Klis SF, Shirwany NA, Moore TG, Rao DB. 2003. Acrylonitrile produces transient cochlear function loss and potentiates permanent noise-induced hearing loss. Toxicol Sci 75:117-123
-
(2003)
Toxicol Sci
, vol.75
, pp. 117-123
-
-
Fechter, L.D.1
Klis, S.F.2
Shirwany, N.A.3
Moore, T.G.4
Rao, D.B.5
-
51
-
-
0031454742
-
Acrylonitrile: A reevaluation of the database to support an inhalation cancer risk assessment
-
Felter SP, Dollarhide JS. 1997. Acrylonitrile: A reevaluation of the database to support an inhalation cancer risk assessment. Reg Toxicol Pharmacol 26:281-287
-
(1997)
Reg Toxicol Pharmacol
, vol.26
, pp. 281-287
-
-
Felter, S.P.1
Dollarhide, J.S.2
-
52
-
-
0025880861
-
Urinary metabolites of [123-13C]acrylonitrile in rats and mice detected by 13C nuclear magnetic resonance spectroscopy
-
Fennell TR, Kedderis GL, Sumner SCJ. 1991. Urinary metabolites of [123-13C]acrylonitrile in rats and mice detected by 13C nuclear magnetic resonance spectroscopy. Chem Res Toxicol 4:678-687
-
(1991)
Chem Res Toxicol
, vol.4
, pp. 678-687
-
-
Fennell, T.R.1
Kedderis, G.L.2
Sumner, S.C.J.3
-
53
-
-
0033928081
-
Hemoglobin adducts from acrylonitrile and ethylene oxide in cigarette smokers: Effects of glutathione S-transferase T1-null and M1-null genotypes
-
Fennell TR, MacNeela JP, Morris RW, Watson M, Thompson CL, Bell DA. 2000. Hemoglobin adducts from acrylonitrile and ethylene oxide in cigarette smokers: Effects of glutathione S-transferase T1-null and M1-null genotypes. Cancer Epidemiol Biomarkers Prev 9:705-712
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, pp. 705-712
-
-
Fennell, T.R.1
MacNeela, J.P.2
Morris, R.W.3
Watson, M.4
Thompson, C.L.5
Bell, D.A.6
-
54
-
-
0037166697
-
Three-generation reproduction study of rats receiving acrylonitrile in drinking water
-
Friedman MA, Beliles RP. 2002. Three-generation reproduction study of rats receiving acrylonitrile in drinking water. Toxicol Lett 32:249-261
-
(2002)
Toxicol Lett
, vol.32
, pp. 249-261
-
-
Friedman, M.A.1
Beliles, R.P.2
-
55
-
-
0031911853
-
Relative neurotoxicological properties of five unsaturated aliphatic nitriles in rats
-
Gagnaire F, Marignac B, Bonnet P. 1998. Relative neurotoxicological properties of five unsaturated aliphatic nitriles in rats. J Appl Toxicol 18:25-31
-
(1998)
J Appl Toxicol
, vol.18
, pp. 25-31
-
-
Gagnaire, F.1
Marignac, B.2
Bonnet, P.3
-
57
-
-
0028785960
-
A physiologically-based dosimetry description of acrylonitrile and cyanoethylene oxide in the rat
-
Gargas ML, Anderson ME, Teo SKO, Batra R, Fennell TR, Kedderis GL. 1995. A physiologically-based dosimetry description of acrylonitrile and cyanoethylene oxide in the rat. Toxicol Appl Pharmacol 134:185-194
-
(1995)
Toxicol Appl Pharmacol
, vol.134
, pp. 185-194
-
-
Gargas, M.L.1
Anderson, M.E.2
Teo, S.K.O.3
Batra, R.4
Fennell, T.R.5
Kedderis, G.L.6
-
58
-
-
0020574194
-
Acrylonitrile-induced gastrointestinal hemorrhage and the effects of metabolism modulation in rats
-
Ghanayem BI, Ahmed AE. 1983. Acrylonitrile-induced gastrointestinal hemorrhage and the effects of metabolism modulation in rats. Toxicol Appl Pharmacol 68:290-296
-
(1983)
Toxicol Appl Pharmacol
, vol.68
, pp. 290-296
-
-
Ghanayem, B.I.1
Ahmed, A.E.2
-
59
-
-
0026070308
-
Assessment of the acute acrylonitrile-induced neurotoxicity in rats
-
Ghanayem BI, Farooqui MY, Elshabrawy O, Mumtaz MM, Ahmed AE. 1991. Assessment of the acute acrylonitrile-induced neurotoxicity in rats. Neurotoxicol Teratol 13:499-502
-
(1991)
Neurotoxicol Teratol
, vol.13
, pp. 499-502
-
-
Ghanayem, B.I.1
Farooqui, M.Y.2
Elshabrawy, O.3
Mumtaz, M.M.4
Ahmed, A.E.5
-
60
-
-
0031427031
-
Effects of the carcinogen acrylonitrile on forestomach cell proliferation and apoptosis in the rat: Comparison with methacrylontrile
-
Ghanayem BI, Elwell MR, Eldridge SR. 1997. Effects of the carcinogen acrylonitrile on forestomach cell proliferation and apoptosis in the rat: Comparison with methacrylontrile. Carcinogenesis 18:675-680
-
(1997)
Carcinogenesis
, vol.18
, pp. 675-680
-
-
Ghanayem, B.I.1
Elwell, M.R.2
Eldridge, S.R.3
-
61
-
-
0035996059
-
Acrylonitrile is a multisite carcinogen in male and female B6C3F1 mice
-
Ghanayem BI, Nyska A, Haseman JK, Bucher JR. 2002. Acrylonitrile is a multisite carcinogen in male and female B6C3F1 mice. Toxicol Sci 68:59-68
-
(2002)
Toxicol Sci
, vol.68
, pp. 59-68
-
-
Ghanayem, B.I.1
Nyska, A.2
Haseman, J.K.3
Bucher, J.R.4
-
62
-
-
84986382966
-
Health care and occupational medicine. Ventox and Ventox intoxication
-
as cited in US EPA, 2007
-
Grunsky F. 1949. Health care and occupational medicine. Ventox and Ventox intoxication. Dtsch Med Wochenschr 74:1081-1083 (as cited in US EPA, 2007).
-
(1949)
Dtsch Med Wochenschr
, vol.74
, pp. 1081-1083
-
-
Grunsky, F.1
-
63
-
-
0021686518
-
Acrylonitrile inhalation in rats: I. Effect on intermediary metabolism
-
Gut I, Nerudova J, Frantik E, Mirejovsk E, Holusa R. 1984. Acrylonitrile inhalation in rats: I. Effect on intermediary metabolism. J Hyg Epidemiol Microbiol Immunol 28:369-376
-
(1984)
J Hyg Epidemiol Microbiol Immunol
, vol.28
, pp. 369-376
-
-
Gut, I.1
Nerudova, J.2
Frantik, E.3
Mirejovsk, E.4
Holusa, R.5
-
64
-
-
0021918252
-
Acrylonitrile inhalation in rats: II. Excretion of thioethers and thiocyanate in urine
-
Gut I, Nerudova J, Stiborova A, Kopecky J, Frantjk E. 1985. Acrylonitrile inhalation in rats: II. Excretion of thioethers and thiocyanate in urine. J Hyg Epidemiol Microbiol Immunol 29:9-13
-
(1985)
J Hyg Epidemiol Microbiol Immunol
, vol.29
, pp. 9-13
-
-
Gut, I.1
Nerudova, J.2
Stiborova, A.3
Kopecky, J.4
Frantjk, E.5
-
66
-
-
0343845359
-
A case of acute dermatitis caused by contact with acrylonitrile
-
as cited in EU, 2004
-
Hashimoto K, Kobayasi T. 1961. A case of acute dermatitis caused by contact with acrylonitrile. Q L Labor Res 9:21-24 (as cited in EU, 2004).
-
(1961)
Q L Labor Res
, vol.9
, pp. 21-24
-
-
Hashimoto, K.1
Kobayasi, T.2
-
67
-
-
76549114907
-
Toxicity of vinyl cyanide
-
Haskell Laboratory. Wilmington, DE: Haskell Laboratory of Industrial Toxicology (as cited in US EPA, 2007)
-
Haskell Laboratory. 1942. Toxicity of vinyl cyanide. Medical Research Project No M-97. Wilmington, DE: Haskell Laboratory of Industrial Toxicology (as cited in US EPA, 2007).
-
(1942)
Medical Research Project No M-97
-
-
-
68
-
-
76549084515
-
-
HSDB (Hazardous Substances Data Bank). National Library of Medicine. [retrieved online June 5, 2007]
-
HSDB (Hazardous Substances Data Bank). 2007. Acrylonitrile. National Library of Medicine. http://toxnetnlmnihgov [retrieved online June 5, 2007].
-
(2007)
Acrylonitrile
-
-
-
70
-
-
34247472532
-
IARC monographs on the evaluation of the carcinogenic risks to humans
-
IARC (International Agency for Research on Cancer). Lyon, France
-
IARC (International Agency for Research on Cancer). 1999. IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans. Reevaluation of Some Organic Chemicals, Hydrazine, and Hydrogen Peroxide. Volume 71. Lyon, France.
-
(1999)
Reevaluation of Some Organic Chemicals, Hydrazine, and Hydrogen Peroxide
, vol.71
-
-
-
72
-
-
0023503042
-
2-Cyanoethylmercapturic acid (CEMA) in the urine as a possible indicator of exposure to acrylonitrile
-
Jakubowski M, Linhart I, Pielas G, Kopecky J. 1987. 2- Cyanoethylmercapturic acid (CEMA) in the urine as a possible indicator of exposure to acrylonitrile. Br J Indust Med 44:834-840
-
(1987)
Br J Indust Med
, vol.44
, pp. 834-840
-
-
Jakubowski, M.1
Linhart, I.2
Pielas, G.3
Kopecky, J.4
-
73
-
-
0026824269
-
Effect of chronic exposure to acryonitrile on subjective symptoms
-
Kaneko Y, Omae K. 1992. Effect of chronic exposure to acryonitrile on subjective symptoms. Keio J Med 41:25-32
-
(1992)
Keio J Med
, vol.41
, pp. 25-32
-
-
Kaneko, Y.1
Omae, K.2
-
74
-
-
0027258742
-
Dose-dependent urinary excretion of acrylonitrile metabolites by rats and mice
-
Kedderis GL, Sumner SCJ, Held SD, Batra R, Turner JJ Jr, Roberts Maio AE, Fennell TR. 1993. Dose-dependent urinary excretion of acrylonitrile metabolites by rats and mice. Toxicol Appl Pharmarcol 120:288-297
-
(1993)
Toxicol Appl Pharmarcol
, vol.120
, pp. 288-297
-
-
Kedderis, G.L.1
Sumner, S.C.J.2
Held, S.D.3
Batra, R.4
Turner Jr., J.J.5
Roberts Maio, A.E.6
Fennell, T.R.7
-
75
-
-
0028863077
-
Conjugation of acrylonitrile and 2-cyanoethylene oxide with hepatic glutathione
-
Kedderis GL, Batra R, Turner MJ Jr. 1995. Conjugation of acrylonitrile and 2-cyanoethylene oxide with hepatic glutathione. Toxicol Appl Pharmacol 135:9-17
-
(1995)
Toxicol Appl Pharmacol
, vol.135
, pp. 9-17
-
-
Kedderis, G.L.1
Batra, R.2
Turner Jr., M.J.3
-
76
-
-
24644469476
-
Development of a Physiologically Based Description of Acrylonitrile Dosimetry
-
January, 1996 (as cited in US EPA, 2007)
-
Kedderis GL, Fennell TR. 1996. Development of a Physiologically Based Description of Acrylonitrile Dosimetry. CIIT Activities, Vol 16, No.1, January, 1996 (as cited in US EPA, 2007).
-
(1996)
CIIT Activities
, vol.16
, Issue.1
-
-
Kedderis, G.L.1
Fennell, T.R.2
-
77
-
-
0018525554
-
Acrylonitrile-epidemiological study-Bayer 1977: A report on a prospective epidemiological study with a past beginning of coworkers at the Leverkusen plant of Bayer AG with acrylonitrile (ACN) exposure
-
(in German) (as cited in ATSDR, 1991)
-
Kiesselbach N, Korallus U, Lange HJ, et al. 1979. [Acrylonitrile- epidemiological study-Bayer 1977: A report on a prospective epidemiological study with a past beginning of coworkers at the Leverkusen plant of Bayer AG with acrylonitrile (ACN) exposure.] Zentralbl Arbeitsmed Arbeitsschutz Prophyl 10:256-259 (in German) (as cited in ATSDR, 1991).
-
(1979)
Zentralbl Arbeitsmed Arbeitsschutz Prophyl
, vol.10
, pp. 256-259
-
-
Kiesselbach, N.1
Korallus, U.2
Lange, H.J.3
-
78
-
-
24644449690
-
Cancer dose-response assessment for acrylonitrile based upon rodent brain tumor incidence: Use of epidemiologic mechanistic and pharmacokinetic support for nonlinearity
-
Kirman CR, Gargas ML, Marsh GM, Strother DE, Klaunig JE, Collins JJ, Deskin R. 2005. Cancer dose-response assessment for acrylonitrile based upon rodent brain tumor incidence: use of epidemiologic mechanistic and pharmacokinetic support for nonlinearity. Regul Toxicol Pharmacol 43:85-103
-
(2005)
Regul Toxicol Pharmacol
, vol.43
, pp. 85-103
-
-
Kirman, C.R.1
Gargas, M.L.2
Marsh, G.M.3
Strother, D.E.4
Klaunig, J.E.5
Collins, J.J.6
Deskin, R.7
-
79
-
-
84951384024
-
Simplified method of evaluating dose-effect experiments
-
Litchfield JT, Wilcoxon F. 1949. Simplified method of evaluating dose-effect experiments. J Pharmacol Exp Ther 96:99-113
-
(1949)
J Pharmacol Exp Ther
, vol.96
, pp. 99-113
-
-
Litchfield, J.T.1
Wilcoxon, F.2
-
80
-
-
0011243565
-
Percutaneous poisoning with acrylonitrile
-
Lorz H. 1950. Percutaneous poisoning with acrylonitrile. Dtsch Med Wochenschr 75:1087-1088
-
(1950)
Dtsch Med Wochenschr
, vol.75
, pp. 1087-1088
-
-
Lorz, H.1
-
81
-
-
0017586264
-
Carcinogenicity bioassays on rats of acrylonitrile administered by inhalation and by ingestion
-
Maltoni C, Cilberti A, Di E. 1977. Carcinogenicity bioassays on rats of acrylonitrile administered by inhalation and by ingestion. Med Lav 69:401-411
-
(1977)
Med Lav
, vol.69
, pp. 401-411
-
-
Maltoni, C.1
Cilberti, A.2
Di, E.3
-
82
-
-
0023740663
-
Long-term carcinogenicity bioassays on acrylonitrile administered by inhalation and by ingestion to Sprague-Dawley rats
-
DOI 10.1111/j.1749-6632.1988.tb30111.x
-
Maltoni C, Cilberti A, Cotti G, Perino G. 1988. Long-term carcinogenicity bioassay on acrylonitrile administered by inhalation and by ingestion to Sprague-Dawley rats. Ann New York Acad Sci 534:179-202 (Pubitemid 18205920)
-
(1988)
Annals of the New York Academy of Sciences
, vol.534
, pp. 179-202
-
-
Maltoni, C.1
Ciliberti, A.2
Cotti, G.3
Perino, G.4
-
83
-
-
0000281247
-
Tests for the induction of unscheduled DNA repair synthesis in HeLa cells
-
Ashby J, de Serres FJ, Draper M, Ishidate M Jr, Margolin BH, Matter BE, Shelby MD, eds. Evaluation of Short-Term Tests for Carcinogens. Report of the International Programme on Chemical Safety's Collaborative Study on In Vitro Assays (as cited in EU, 2004)
-
Martin CNC. 1985. Tests for the induction of unscheduled DNA repair synthesis in HeLa cells. In: Ashby J, de Serres FJ, Draper M, Ishidate M Jr, Margolin BH, Matter BE, Shelby MD, eds. Evaluation of Short-Term Tests for Carcinogens. Report of the International Programme on Chemical Safety's Collaborative Study on In Vitro Assays. Prog Mutat Res 5:375-379 (as cited in EU, 2004).
-
(1985)
Prog Mutat Res
, vol.5
, pp. 375-379
-
-
Martin, C.N.C.1
-
84
-
-
0024206205
-
Biochemical and developmental effects in rats following in utero exposure to acrylonitrile: A preliminary report
-
Mehrotra J, Khanna VK, Husain R, Seth PK. 1988. Biochemical and developmental effects in rats following in utero exposure to acrylonitrile: A preliminary report. Ind Health 26:251-255
-
(1988)
Ind Health
, vol.26
, pp. 251-255
-
-
Mehrotra, J.1
Khanna, V.K.2
Husain, R.3
Seth, P.K.4
-
85
-
-
0018077977
-
Cancer mortality and morbidity among rubber workers
-
as cited in EU, 2004
-
Monson RR, Fine LJ. 1978. Cancer mortality and morbidity among rubber workers. J Nat Cancer Inst 61:290-293 (as cited in EU, 2004).
-
(1978)
J Nat Cancer Inst
, vol.61
, pp. 290-293
-
-
Monson, R.R.1
Fine, L.J.2
-
86
-
-
0023280198
-
Urinary excretion of acrylonitrile and its metabolites in rats
-
Müller G, Verkoyen C, Soton N, Norpoth K. 1987. Urinary excretion of acrylonitrile and its metabolites in rats. Arch Toxicol 60:464-466
-
(1987)
Arch Toxicol
, vol.60
, pp. 464-466
-
-
Müller, G.1
Verkoyen, C.2
Soton, N.3
Norpoth, K.4
-
87
-
-
70350511301
-
-
Midland MI: Toxicological Research Laboratory Health and Environmental Research, Dow Chemical, USA
-
Murray FJ, Nitschke KD, John JA, Crawford AA, Murray JS, Rampy LW, Schwetz BA. 1978. Teratologic evaluation of inhaled acrylonitrile monomer in rats. Midland MI: Toxicological Research Laboratory Health and Environmental Research, Dow Chemical, USA.
-
(1978)
Teratologic Evaluation of Inhaled Acrylonitrile Monomer in Rats
-
-
Murray, F.J.1
Nitschke, K.D.2
John, J.A.3
Crawford, A.A.4
Murray, J.S.5
Rampy, L.W.6
Schwetz, B.A.7
-
88
-
-
0026927952
-
Health profiles of workers exposed to acrylonitrile
-
as cited in WHO, 2002
-
Muto T, Sakurai H, Omae K, Minaguchi H, Tachi M. 1992. Health profiles of workers exposed to acrylonitrile. Keio J Med 41:154-160 (as cited in WHO, 2002).
-
(1992)
Keio J Med
, vol.41
, pp. 154-160
-
-
Muto, T.1
Sakurai, H.2
Omae, K.3
Minaguchi, H.4
Tachi, M.5
-
89
-
-
39749126105
-
Two-generation reproductive toxicity study of inhaled acrylonitrile vapors in Crl: CD(SD) rats
-
Nemec MD, Kirkpatrick DT, Sherman J, Van Miller JP, Pershing M ML, Strother DE. 2008. Two-generation reproductive toxicity study of inhaled acrylonitrile vapors in Crl:CD(SD) rats. Int J Toxicol 27:11-29
-
(2008)
Int J Toxicol
, vol.27
, pp. 11-29
-
-
Nemec, M.D.1
Kirkpatrick, D.T.2
Sherman, J.3
Van Miller, J.P.4
Pershing, M.M.L.5
Strother, D.E.6
-
90
-
-
0024427226
-
Effects of cysteine isomers and derivatives on acute acrylonitrile toxicity
-
as cited in US EPA, 2007
-
Nerland EE, Benz FW, Babiuk C. 1989. Effects of cysteine isomers and derivatives on acute acrylonitrile toxicity. Drug Metab Rev 20:233-246 (as cited in US EPA, 2007).
-
(1989)
Drug Metab Rev
, vol.20
, pp. 233-246
-
-
Nerland, E.E.1
Benz, F.W.2
Babiuk, C.3
-
92
-
-
0009819039
-
Toxicology and carcinogenesis studies of acrylonitrile in B6C3F1 mice (gavage studies)
-
NTP (National Toxicology Program)
-
NTP (National Toxicology Program). 2001. Toxicology and carcinogenesis studies of acrylonitrile in B6C3F1 mice (gavage studies). NTP Technical Report Series. Vol.506.
-
(2001)
NTP Technical Report Series
, vol.506
-
-
-
93
-
-
76549089490
-
Report on carcinogens
-
NTP (National Toxicology Program). 11th ed. US Department of Health and Human Services, Public Health Service, National Toxicology Program
-
NTP (National Toxicology Program). 2006. Report on Carcinogens. Acrylonitrile. 11th ed. US Department of Health and Human Services, Public Health Service, National Toxicology Program.
-
(2006)
Acrylonitrile
-
-
-
94
-
-
0002808462
-
Tests for the induction of sister-chromatid exchanges in human peripheral lymphocytes in culture
-
Ashby J, de Serres FJ, Draper M, Ishidate M Jr, Margolin BH, Matter BE, Shelby MD, eds. Evaluation of Short-Term Tests for Carcinogens. Report of the International Programme on Chemical Safety's Collaborative Study on In Vitro Assays. (as cited in EU, 2004)
-
Obe G, Hille A, Jonas R, Schmidt S, Thenhaus U. 1985. Tests for the induction of sister-chromatid exchanges in human peripheral lymphocytes in culture. In: Ashby J, de Serres FJ, Draper M, Ishidate M Jr, Margolin BH, Matter BE, Shelby MD, eds. Evaluation of Short-Term Tests for Carcinogens. Report of the International Programme on Chemical Safety's Collaborative Study on In Vitro Assays. Prog Mutat Res 5:439-442 (as cited in EU, 2004).
-
(1985)
Prog Mutat Res
, vol.5
, pp. 439-442
-
-
Obe, G.1
Hille, A.2
Jonas, R.3
Schmidt, S.4
Thenhaus, U.5
-
95
-
-
0018864318
-
Epidemiologic study of workers exposed to acrylonitrile
-
as cited in ATSDR, 1991
-
O'Berg MT. 1980. Epidemiologic study of workers exposed to acrylonitrile. J Occup Med 22:245-252 (as cited in ATSDR, 1991).
-
(1980)
J Occup Med
, vol.22
, pp. 245-252
-
-
O'Berg, M.T.1
-
96
-
-
0022403626
-
Epidemiologic study of workers exposed to acrylonitrile: An update
-
as cited in ATSDR, 1991
-
O'Berg MT, Chen JL, Burke CA, et al. 1985. Epidemiologic study of workers exposed to acrylonitrile: An update. J Occup Med 27:835-840 (as cited in ATSDR, 1991).
-
(1985)
J Occup Med
, vol.27
, pp. 835-840
-
-
O'Berg, M.T.1
Chen, J.L.2
Burke, C.A.3
-
97
-
-
76549092430
-
Acrylonitrile
-
O'Neil M Smith A, Heckelman PE, Obenchain JR Jr, Gallipeau J R, D'Arecca MA, eds., 13th ed. Whitehouse Station, NJ: Merck & Co., Inc
-
O'Neil M Smith A, Heckelman PE, Obenchain JR Jr, Gallipeau J R, D'Arecca MA, eds. 2001. Acrylonitrile. In: The Merck Index. 13th ed. Whitehouse Station, NJ: Merck & Co., Inc.
-
(2001)
The Merck Index
-
-
-
98
-
-
0031600999
-
Biological Monitoring of acrylonitrile exposure
-
as cited in US EPA, 2007
-
Perbellini L, Ganzi A, Venturi G, Cerpelloni M, Brugnone F. 1998. Biological Monitoring of acrylonitrile exposure. G Ital Med Lav Ergon 20:10-14 (as cited in US EPA, 2007).
-
(1998)
G Ital Med Lav Ergon
, vol.20
, pp. 10-14
-
-
Perbellini, L.1
Ganzi, A.2
Venturi, G.3
Cerpelloni, M.4
Brugnone, F.5
-
99
-
-
0020351182
-
Increase in sister chromatid exchange and unscheduled synthesis of deoxyribonucleic acid by acrylonitrile in human lymphocytes in vitro
-
as cited in US EPA, 2007
-
Perocco P, Pane G, Bolognesi S, Zannotti M. 1982. Increase in sister chromatid exchange and unscheduled synthesis of deoxyribonucleic acid by acrylonitrile in human lymphocytes in vitro. Scand J Work Environ Health 2-8:290-293 (as cited in US EPA, 2007).
-
(1982)
Scand J Work Environ Health
, vol.2-8
, pp. 290-293
-
-
Perocco, P.1
Pane, G.2
Bolognesi, S.3
Zannotti, M.4
-
100
-
-
0021683551
-
Experimental pharmacokinetics and toxicology of acrylonitrile
-
as cited in EU, 2004
-
Peter H, Bolt HM 1984 Experimental pharmacokinetics and toxicology of acrylonitrile. G Ital Med Lav 6:77-81 (as cited in EU, 2004).
-
(1984)
G Ital Med Lav
, vol.6
, pp. 77-81
-
-
Peter, H.1
Bolt, H.M.2
-
101
-
-
0023718372
-
Effect of glutathione depletion on the uptake of acrylonitrile vapors and on its irreversible association with tissue macromolecules
-
DOI 10.1016/0041-008X(88)90163-9
-
Pilon D, Roberts AE, Rickert DE. 1988a. Effect of glutathione depletion on the uptake of acrylonitrile vapors and on its irreversible association with tissue macromolecules. Toxicol Appl Pharmacol 95:265-278 (Pubitemid 18243377)
-
(1988)
Toxicology and Applied Pharmacology
, vol.95
, Issue.2
, pp. 265-278
-
-
Pilon, D.1
Roberts, A.E.2
Rickert, D.E.3
-
102
-
-
0023676046
-
Effect of glutathione depletion on the irreversible association of acrylonitrile with tissue macromolecules after oral administration to rats
-
DOI 10.1016/0041-008X(88)90167-6
-
Pilon D, Roberts AE, Rickert DE. 1988b. Effect of glutathione depletion on the irreversible association of acrylonitrile with tissue macromolecules after oral administration to rats. Toxicol Appl Pharmacol 95:311-320 (as cited in EU, 2004). (Pubitemid 18243381)
-
(1988)
Toxicology and Applied Pharmacology
, vol.95
, Issue.2
, pp. 311-320
-
-
Pilon, D.1
Roberts, A.E.2
Rickert, D.E.3
-
103
-
-
0037166696
-
Two-year toxicity and oncogenicity study with acrylonitrile incorporated in the drinking water of rats
-
Quast JF. 2002. Two-year toxicity and oncogenicity study with acrylonitrile incorporated in the drinking water of rats. Toxicol Lett 132:153-196
-
(2002)
Toxicol Lett
, vol.132
, pp. 153-196
-
-
Quast, J.F.1
-
105
-
-
0003819292
-
-
Midland MI: Dow Chemical Co Toxicology Research Laboratory
-
Quast JF, Schuetz DJ, Balmer MF, Gushow TS, Park CN, McKenna MJ. 1980. A two-year toxicity and oncogenicity study with acrylonitrile following inhalation exposure of rats. Midland MI: Dow Chemical Co Toxicology Research Laboratory.
-
(1980)
A Two-year Toxicity and Oncogenicity Study with Acrylonitrile Following Inhalation Exposure of Rats
-
-
Quast, J.F.1
Schuetz, D.J.2
Balmer, M.F.3
Gushow, T.S.4
Park, C.N.5
McKenna, M.J.6
-
106
-
-
27644500051
-
Mutational specifity of 2-cyanoethylene oxide in human lymphoblastoid cells
-
as cited in US EPA, 2007
-
Recio L, Simpson D, Cocharane J, Liber H, Skopek TR. 1989. Mutational specifity of 2-cyanoethylene oxide in human lymphoblastoid cells. Environ Mol Mutagen 14:162 (as cited in US EPA, 2007).
-
(1989)
Environ Mol Mutagen
, vol.14
, pp. 162
-
-
Recio, L.1
Simpson, D.2
Cocharane, J.3
Liber, H.4
Skopek, T.R.5
-
107
-
-
0025038456
-
Molecular analysis of hprt mutants induced by 2-cyanoethylene oxide in human lymphoblastoid cells
-
as cited in US EPA, 2007
-
Recio L, Simpson D, Cochrane J, Liber H, Skopek TR. 1990. Molecular analysis of hprt mutants induced by 2-cyanoethylene oxide in human lymphoblastoid cells. Mutat Res 242:195-208 (as cited in US EPA, 2007).
-
(1990)
Mutat Res
, vol.242
, pp. 195-208
-
-
Recio, L.1
Simpson, D.2
Cochrane, J.3
Liber, H.4
Skopek, T.R.5
-
108
-
-
76549100340
-
Acrylonitrile: Mutagenicity in yeasts and genotoxicity in HeLa cells
-
US EPA, 2007
-
Rizzi R, Chiesara E, Cova D, Mattioli M, Lernia R. 1984. Acrylonitrile: Mutagenicity in yeasts and genotoxicity in HeLa cells. Mutat Res 130:223 (US EPA, 2007).
-
(1984)
Mutat Res
, vol.130
, pp. 223
-
-
Rizzi, R.1
Chiesara, E.2
Cova, D.3
Mattioli, M.4
Lernia, R.5
-
109
-
-
0025811996
-
Species comparison of acrylonitrile expoxidation by microsomes from mice rats and humans: Relationship to epoxide concentrations in mouse and rat blood
-
as cited in US EPA, 2007
-
Roberts AE, Kedderis GL, Turner MJ, Rickert DE, Swenberg JA. 1991. Species comparison of acrylonitrile expoxidation by microsomes from mice rats and humans: Relationship to epoxide concentrations in mouse and rat blood. Carcinogenesis 12:401-404 (as cited in US EPA, 2007).
-
(1991)
Carcinogenesis
, vol.12
, pp. 401-404
-
-
Roberts, A.E.1
Kedderis, G.L.2
Turner, M.J.3
Rickert, D.E.4
Swenberg, J.A.5
-
110
-
-
0027960228
-
Cancer occurrence among workers exposed to acrylonitrile
-
as cited in EU, 2004
-
Rothman KJ. 1994. Cancer occurrence among workers exposed to acrylonitrile. Scan J Work Environ Health 20:313-321 (as cited in EU, 2004).
-
(1994)
Scan J Work Environ Health
, vol.20
, pp. 313-321
-
-
Rothman, K.J.1
-
113
-
-
0027477883
-
Modulation of acrylonitrile-induced embryotoxicity in vitro by glutathion depletion
-
Saillenfait AM, Payan JP, Langonne I, Beydon D, Grandclaude MC, Sabate JP, de Ceaurriz J. 1993b. Modulation of acrylonitrile-induced embryotoxicity in vitro by glutathion depletion. Arch Toxicol 67:164-172
-
(1993)
Arch Toxicol
, vol.67
, pp. 164-172
-
-
Saillenfait, A.M.1
Payan, J.P.2
Langonne, I.3
Beydon, D.4
Grandclaude, M.C.5
Sabate, J.P.6
De Ceaurriz, J.7
-
114
-
-
0034162017
-
Comparative developmental toxicities of aliphatic nitriles: In vivo and in vitro observations
-
Saillenfait AM, Sabate JP. 2000. Comparative developmental toxicities of aliphatic nitriles: in vivo and in vitro observations. Toxicol Appl Pharmacol 163:149-163
-
(2000)
Toxicol Appl Pharmacol
, vol.163
, pp. 149-163
-
-
Saillenfait, A.M.1
Sabate, J.P.2
-
115
-
-
0343845358
-
Epidemiological study of health impairment among acrylonitrile workers
-
as cited in US EPA, 2007
-
Sakurai H, Kusumoto M. 1972. Epidemiological study of health impairment among acrylonitrile workers. J Sci Labor 48:273-282 (as cited in US EPA, 2007).
-
(1972)
J Sci Labor
, vol.48
, pp. 273-282
-
-
Sakurai, H.1
Kusumoto, M.2
-
116
-
-
0018159696
-
Health effects of acrylonitrile in acrylic fibre factories
-
Sakurai H, Onodera M, Utsunomiya T, Minakuchi H, Iwai H, Mutsumura H. 1978. Health effects of acrylonitrile in acrylic fibre factories. Br J Ind Med 35:219-225
-
(1978)
Br J Ind Med
, vol.35
, pp. 219-225
-
-
Sakurai, H.1
Onodera, M.2
Utsunomiya, T.3
Minakuchi, H.4
Iwai, H.5
Mutsumura, H.6
-
117
-
-
0019225404
-
Distribution of (14-C)acrylonitrile in rat and monkey
-
Sandberg EC, Slanina P. 1980. Distribution of (14-C)acrylonitrile in rat and monkey. Toxicol Lett 6:187-191
-
(1980)
Toxicol Lett
, vol.6
, pp. 187-191
-
-
Sandberg, E.C.1
Slanina, P.2
-
118
-
-
76549091209
-
-
Sapphire Group, Inc. Prepared for the AN Group. The Sapphire Group, Inc., Dayton and Cleveland. OH. Final, October 2004
-
Sapphire Group, Inc. 2004. Toxicological Review for Acrylonitrile (CAS No. 107-13-1). Prepared for the AN Group. The Sapphire Group, Inc., Dayton and Cleveland. OH. Final, October 2004.
-
(2004)
Toxicological Review for Acrylonitrile (CAS No. 107-13-1)
-
-
-
119
-
-
0003588671
-
-
Birmingham, AL: Southern Research Institute (SRI-LIF-95-593-8618-1) (as cited in EU, 2004)
-
Serota DG, Giles HD, Coyne JM, Hogan DB. 1996. Subchronic toxicity study in B6C3F1 mice. Birmingham, AL: Southern Research Institute (SRI-LIF-95-593- 8618-1) (as cited in EU, 2004).
-
(1996)
Subchronic Toxicity Study in B6C3F1 Mice
-
-
Serota, D.G.1
Giles, H.D.2
Coyne, J.M.3
Hogan, D.B.4
-
121
-
-
0032750641
-
Role of Cytochrome P450 2E1 in the metabolism of acrylamide and acrylonitrile in mice
-
as cited in US EPA, 2007
-
Sumner SC, Fennell TR, Moore TA, Chanas B, Gonzalez F, Ghanayem BI. 1999. Role of Cytochrome P450 2E1 in the metabolism of acrylamide and acrylonitrile in mice. Chem Res Toxicol 12:1110-1116 (as cited in US EPA, 2007).
-
(1999)
Chem Res Toxicol
, vol.12
, pp. 1110-1116
-
-
Sumner, S.C.1
Fennell, T.R.2
Moore, T.A.3
Chanas, B.4
Gonzalez, F.5
Ghanayem, B.I.6
-
122
-
-
0026742553
-
Mortality of workers exposed to acrylonitrile
-
as cited in EU, 2004
-
Swaen GMH, Bloemen LJN, Twisk J, Scheffers T, Slangen JM, Sturmans F. 1992. Mortality of workers exposed to acrylonitrile. J Occup Med 34:801-809 (as cited in EU, 2004).
-
(1992)
J Occup Med
, vol.34
, pp. 801-809
-
-
Swaen, G.M.H.1
Bloemen, L.J.N.2
Twisk, J.3
Scheffers, T.4
Slangen, J.M.5
Sturmans, F.6
-
123
-
-
0031817294
-
Mortality of workers exposed to acrylonitrile in the Netherlands
-
as cited in EU, 2004
-
Swaen GMH, Bloemen LJN, Twisk J, Scheffers T, Slangen JM, Collins JJ, ten Berge WJF, Sturmans F. 1998. Mortality of workers exposed to acrylonitrile in the Netherlands. Scand J Work Environ Health 22:10-16 (as cited in EU, 2004).
-
(1998)
Scand J Work Environ Health
, vol.22
, pp. 10-16
-
-
Swaen, G.M.H.1
Bloemen, L.J.N.2
Twisk, J.3
Scheffers, T.4
Slangen, J.M.5
Collins, J.J.6
Ten Berge, W.J.F.7
Sturmans, F.8
-
124
-
-
3242741014
-
Mortality update of workers exposed to acrylonitrile in the Netherlands
-
Swaen GMH, Bloemen LJN, Twisk J, Scheffers T, Slangen JM, Collins JJ, ten Berge WJF. 2004. Mortality update of workers exposed to acrylonitrile in the Netherlands. J Occup Med 46:691-698
-
(2004)
J Occup Med
, vol.46
, pp. 691-698
-
-
Swaen, G.M.H.1
Bloemen, L.J.N.2
Twisk, J.3
Scheffers, T.4
Slangen, J.M.5
Collins, J.J.6
Ten Berge, W.J.F.7
-
125
-
-
0037253723
-
Physiologically based pharmacokinetic model parameter estimation and sensitivity and variability analyses for acrylonitrile deposition in humans
-
Sweeney LM, Gargas ML, Strother DE, Kedderis GL. 2003. Physiologically based pharmacokinetic model parameter estimation and sensitivity and variability analyses for acrylonitrile deposition in humans. Toxicol Sci 71:27-40
-
(2003)
Toxicol Sci
, vol.71
, pp. 27-40
-
-
Sweeney, L.M.1
Gargas, M.L.2
Strother, D.E.3
Kedderis, G.L.4
-
126
-
-
43549104027
-
Mortality among workers exposed to acrylonitrile in fiber production: An update
-
Symons JM, Kreckmann KH, Sakr CJ, Kaplan AM, Leonard RC. 2008. Mortality among workers exposed to acrylonitrile in fiber production: An update. J Occup Environ Med 50:550-560
-
(2008)
J Occup Environ Med
, vol.50
, pp. 550-560
-
-
Symons, J.M.1
Kreckmann, K.H.2
Sakr, C.J.3
Kaplan, A.M.4
Leonard, R.C.5
-
127
-
-
0021612320
-
Subacute and chronic action of acrylonitrile on adrenals and gastrointestinal tract: Biochemical functional and ultrastructural studies in the rat
-
Szabo S, Gallagher GT, Silver EH, Maull EA, Horner HC, Komanicky P, Melby JC, McComb DJ, Kovacs K. 1984. Subacute and chronic action of acrylonitrile on adrenals and gastrointestinal tract: Biochemical functional and ultrastructural studies in the rat. J Appl Toxicol 4:131-140
-
(1984)
J Appl Toxicol
, vol.4
, pp. 131-140
-
-
Szabo, S.1
Gallagher, G.T.2
Silver, E.H.3
Maull, E.A.4
Horner, H.C.5
Komanicky, P.6
Melby, J.C.7
McComb, D.J.8
Kovacs, K.9
-
128
-
-
0023949397
-
Testicular effects of acrylonitrile in mice
-
Tandon R, Saxena DK, Chandra SV, Seth PK, Srivastava SP. 1988. Testicular effects of acrylonitrile in mice. Toxicol Lett 42:55-63
-
(1988)
Toxicol Lett
, vol.42
, pp. 55-63
-
-
Tandon, R.1
Saxena, D.K.2
Chandra, S.V.3
Seth, P.K.4
Srivastava, S.P.5
-
129
-
-
0024398563
-
Nitrile-induced behavioral abnormalities in mice
-
Tanii H, Hayashi M, Hashimoto L. 1989. Nitrile-induced behavioral abnormalities in mice. Neurotoxicology 10:157-165
-
(1989)
Neurotoxicology
, vol.10
, pp. 157-165
-
-
Tanii, H.1
Hayashi, M.2
Hashimoto, L.3
-
130
-
-
0023640335
-
Urinary excretion of mercapturic acids and thiocyanate in rats exposed to acrylonitrile: Influence of dose and route of administration
-
Tardif R, Talbot D, Grin M, Brodeur J. 1987. Urinary excretion of mercapturic acids and thiocyanate in rats exposed to acrylonitrile: Influence of dose and route of administration. Toxicol Lett 39:255-261
-
(1987)
Toxicol Lett
, vol.39
, pp. 255-261
-
-
Tardif, R.1
Talbot, D.2
Grin, M.3
Brodeur, J.4
-
131
-
-
0022763367
-
Concentration-time mortality response relationship of irritant and systemically acting vapours and gases
-
Ten Berge WF, Zwart A, Appelman LM. 1986. Concentration-time mortality response relationship of irritant and systemically acting vapours and gases. J Hazard Mat 13:301-309
-
(1986)
J Hazard Mat
, vol.13
, pp. 301-309
-
-
Ten Berge, W.F.1
Zwart, A.2
Appelman, L.M.3
-
132
-
-
0018068384
-
Analysis of chromosomes of workers exposed to acrylonitrile
-
as cited in US EPA, 2007
-
Thiess AM, Fleig I. 1978. Analysis of chromosomes of workers exposed to acrylonitrile. Arch Toxicol 41:149-152 (as cited in US EPA, 2007).
-
(1978)
Arch Toxicol
, vol.41
, pp. 149-152
-
-
Thiess, A.M.1
Fleig, I.2
-
133
-
-
0019285991
-
Mortalitatssstudie bei chemiefacharbeitern verschiedener produktionsbetrieve mit exposition auch gegenuber acrylonitril
-
as cited in EU, 2007
-
Thiess AM, Frentzel-Beyme R, Link R, Wild H. 1980. Mortalitatssstudie bei chemiefacharbeitern verschiedener produktionsbetrieve mit exposition auch gegenuber acrylonitril. Zentralbl Arbeitsmed Arbeitssch Prophyl Ergonomie 30:259-267 (as cited in EU, 2007).
-
(1980)
Zentralbl Arbeitsmed Arbeitssch Prophyl Ergonomie
, vol.30
, pp. 259-267
-
-
Thiess, A.M.1
Frentzel-Beyme, R.2
Link, R.3
Wild, H.4
-
134
-
-
76549108151
-
-
retrieved online July 30, 2007
-
US EPA (Environmental Protection Agency). 1991. Integrated Risk Information System on Acrylonitrile. http://wwwepagov/iris/subst/0206htm [retrieved online July 30, 2007].
-
(1991)
Integrated Risk Information System on Acrylonitrile
-
-
-
136
-
-
0019449472
-
Formation of mercapturic acids from acrylonitrile crotononitrile and cinnamonitrile by direct conjugation and via an intermediate oxidation process
-
as cited in EU, 2004
-
Van Bladeren PJ, Delbressine LPC, Hoogeterp JJ, Beaumont AHGM, Breimer DD, Seutter-Berlage F, van der Gen A. 1981. Formation of mercapturic acids from acrylonitrile crotononitrile and cinnamonitrile by direct conjugation and via an intermediate oxidation process. Drug Meta Disp 9:246-249 (as cited in EU, 2004).
-
(1981)
Drug Meta Disp
, vol.9
, pp. 246-249
-
-
Van Bladeren, P.J.1
Delbressine, L.P.C.2
Hoogeterp, J.J.3
Ahgm, B.4
Breimer, D.D.5
Seutter-Berlage, F.6
Van Der Gen, A.7
-
137
-
-
0000098119
-
Acute toxicologic evaluation of acrylonitrile
-
as cited in US EPA, 2007
-
Vernon PA, Dulak L H, Deskin R. 1990. Acute toxicologic evaluation of acrylonitrile. J Amer Coll Toxicol 1:114-115 (as cited in US EPA, 2007).
-
(1990)
J Amer Coll Toxicol
, vol.1
, pp. 114-115
-
-
Vernon, P.A.1
Dulak, L.H.2
Deskin, R.3
-
138
-
-
0021237839
-
Acrylonitrile (vinyl cyanide) poisoning: A case report
-
as cited in US EPA, 2007
-
Vogel RA, Kirkendall WM. 1984. Acrylonitrile (vinyl cyanide) poisoning: A case report. Texas Med 80:48-51 (as cited in US EPA, 2007).
-
(1984)
Texas Med
, vol.80
, pp. 48-51
-
-
Vogel, R.A.1
Kirkendall, W.M.2
-
139
-
-
0027517417
-
Comparison of cancer risks projected from animal bioassays to epidemiologic studies of acrylonitrile workers
-
Ward CE, Starr TB. 1993. Comparison of cancer risks projected from animal bioassays to epidemiologic studies of acrylonitrile workers. Regul Toxicol Pharmacol 18:214-232
-
(1993)
Regul Toxicol Pharmacol
, vol.18
, pp. 214-232
-
-
Ward, C.E.1
Starr, T.B.2
-
140
-
-
76549104846
-
An epidemiological study on reproductive effects in female workers exposed to acrylonitrile
-
as cited in EU, 2004
-
Weiai W, Jiang S, Meiyuan H. 1995. An epidemiological study on reproductive effects in female workers exposed to acrylonitrile. Chinese Prevent Med Mag 29 (as cited in EU, 2004).
-
(1995)
Chinese Prevent Med Mag
, vol.29
-
-
Weiai, W.1
Jiang, S.2
Meiyuan, H.3
-
141
-
-
0019453928
-
Mortality of United Kingdom acrylonitrile polymerisation workers
-
as cited in ATSDR, 1991
-
Werner JB, Carter JT. 1981. Mortality of United Kingdom acrylonitrile polymerisation workers. Br J Ind Med 38:247-253 (as cited in ATSDR, 1991).
-
(1981)
Br J Ind Med
, vol.38
, pp. 247-253
-
-
Werner, J.B.1
Carter, J.T.2
-
143
-
-
85040379892
-
Acrylonitrile
-
WHO IPCS (World Health Organization International Programme on Chemical Safety)
-
WHO IPCS (World Health Organization International Programme on Chemical Safety). 1983. Acrylonitrile. Environ Health Criteria. No.28.
-
(1983)
Environ Health Criteria
, vol.28
-
-
-
144
-
-
76549117621
-
Concise international chemical assessment document 39
-
WHO (World Health Organization). Geneva, Switzerland. WIL Research Laboratories 2005 Acute inhalation toxicity study of acrylonitrile in albino rats WIL Research Laboratories Ashland OH WIL-542001
-
WHO (World Health Organization). 2002. Concise International Chemical Assessment Document 39. Acrylonitrile. Geneva, Switzerland. WIL Research Laboratories 2005 Acute inhalation toxicity study of acrylonitrile in albino rats WIL Research Laboratories Ashland OH WIL-542001
-
(2002)
Acrylonitrile
-
-
-
145
-
-
0019521510
-
The role of cyanide liberation in the acute toxicity of aliphatic nitriles
-
Willhite CC, Smith RP. 1981. The role of cyanide liberation in the acute toxicity of aliphatic nitriles. Toxicol Appl Pharmacol 59:589-602
-
(1981)
Toxicol Appl Pharmacol
, vol.59
, pp. 589-602
-
-
Willhite, C.C.1
Smith, R.P.2
-
146
-
-
0343409417
-
Medical problems encountered in the manufacture of American-made rubber
-
Wilson RH, Hough GV, McCormick WE. 1948. Medical problems encountered in the manufacture of American-made rubber. Indust Med 17:199-207
-
(1948)
Indust Med
, vol.17
, pp. 199-207
-
-
Wilson, R.H.1
Hough, G.V.2
McCormick, W.E.3
-
147
-
-
0031815302
-
Mortality and morbidity of workers exposed to acrylonitrile in fibre production
-
as cited in EU, 2004
-
Wood SM, Buffler PA, Burau K, Krivanek N. 1998. Mortality and morbidity of workers exposed to acrylonitrile in fibre production. Scand J Work Environ Health 2:54-62 (as cited in EU, 2004).
-
(1998)
Scand J Work Environ Health
, vol.2
, pp. 54-62
-
-
Wood, S.M.1
Buffler, P.A.2
Burau, K.3
Krivanek, N.4
-
148
-
-
0023337010
-
Comparison of the dominant lethal effects of acrylonitrile and acrylamide in male Fischer 344 rats
-
Working PK, Bentley KS, Hurtt ME, Mohr KL. 1987. Comparison of the dominant lethal effects of acrylonitrile and acrylamide in male Fischer 344 rats. Mutagenesis 2:215-220
-
(1987)
Mutagenesis
, vol.2
, pp. 215-220
-
-
Working, P.K.1
Bentley, K.S.2
Hurtt, M.E.3
Mohr, K.L.4
-
149
-
-
17044456990
-
Toxicity of nitriles Results of animal experiments and industrial experiences during 15 years
-
as cited in EU, 2004
-
Zeller H, Hofmann HT, Theiss AM, Hey W. 1969. Toxicity of nitriles Results of animal experiments and industrial experiences during 15 years. Zbl Arbeitsmed Arbeitsschutz 19:225-237 (as cited in EU, 2004).
-
(1969)
Zbl Arbeitsmed Arbeitsschutz
, vol.19
, pp. 225-237
-
-
Zeller, H.1
Hofmann, H.T.2
Theiss, A.M.3
Hey, W.4
|