Acrylonitrile is a multisite carcinogen in male and female B6C3F1 mice

Toxicological Sciences

Volumn 68, Issue 1, 2002, Pages 59-68

  Ghanayem, Burhan I ^a   Nyska, Abraham ^a   Haseman, Joseph K ^a   Bucher, John R ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Acrylonitrile; B6C3F1 mice; Carcinogenicity; Forestomach; Harderian gland; Lung; Ovary

Indexed keywords

ACRYLONITRILE; BIOCHEMICAL MARKER; CARCINOGEN; CYSTEINE DERIVATIVE; DRINKING WATER; NITRILE; THIOCYANATE;

ADENOMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATROPHY; CANCER INCIDENCE; CARCINOGEN TESTING; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; EPITHELIUM HYPERPLASIA; EYE CANCER; FEEDING; FEMALE; FORESTOMACH; GENDER; GRANULOSA CELL TUMOR; HARDER GLAND; INHALATION; LONG TERM EXPOSURE; LUNG ALVEOLUS CELL CARCINOMA; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; OVARY CYST; OVARY TUMOR; PAPILLOMA; SPECIES DIFFERENCE; SURVIVAL RATE; SYNTHESIS; URINALYSIS; ANIMAL; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG EFFECT; EXPERIMENTAL NEOPLASM; LONGEVITY; METHODOLOGY; MULTIPLE CANCER; PATHOLOGY;

ACRYLONITRILE; ANIMAL; CARCINOGENICITY TESTS; CARCINOGENS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; LONGEVITY; MALE; MICE; MICE, INBRED STRAINS; NEOPLASMS, EXPERIMENTAL; NEOPLASMS, MULTIPLE PRIMARY; SUPPORT, U.S. GOV'T, P.H.S.; ANIMALS;

ANIMALIA;

EID: 0035996059     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/68.1.59     Document Type: Article

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