Induction of apoptosis by esculetin in human leukemia U937 cells: Roles of Bcl-2 and extracellular-regulated kinase signaling

Toxicology in Vitro

Volumn 24, Issue 2, 2010, Pages 486-494

  Park, Cheol ^a   Jin, Cheng Yun ^a   Kwon, Hyun Ju ^a,b   Hwang, Hye Jin ^a,c   Kim, Gi Young ^d   Choi, Il Whan ^e   Kwon, Taeg Kyu ^f   Kim, Byung Woo ^a,b   Kim, Wun Jae ^g   Choi, Yung Hyun ^a,h  

^a Dong Eui University   (South Korea)

^b Department of Life Science and Biotechnology   (South Korea)

^c Department of Food and Nutrition   (South Korea)

^d Jeju National University   (South Korea)

^e Inje University College of Medicine   (South Korea)

^f Keimyung University   (South Korea)

^g Chungbuk National University College of Medicine   (South Korea)

^h Dong Eui University   (South Korea)

Author keywords

Apoptosis; Bcl 2; ERK; Esculetinl; HA14 1

Indexed keywords

2 AMINO 6 BROMO 4 (1 CYANO 2 ETHOXY 2 OXOETHYL) 4H CHROMENE 3 CARBOXYLIC ACID ETHYL ESTER; CASPASE; DEATH RECEPTOR 4; ESCULETIN; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BID;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN U937; CONTROLLED STUDY; DRUG SENSITIVITY; ENZYME ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

APOPTOSIS; BENZOPYRANS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; GENES, BCL-2; HUMANS; NITRILES; U937 CELLS; UMBELLIFERONES;

EID: 76549097665     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.09.017     Document Type: Article

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