Small conductance calcium-activated K+ channels, SkCa, but not voltage-gated K+ (Kv) channels, are implicated in the antinociception induced by CGS21680, a A2A adenosine receptor agonist

Life Sciences

Volumn 76, Issue 4, 2004, Pages 367-377

  Regaya, I ^a,b   Pham, T ^c   Andreotti, N ^d   Sauze, N ^a   Carrega, L ^a,d   Martin Eauclaire, M F ^a   Jouirou, B ^a,b   Peragut, J C ^d   Vacher, H ^a   Rochat, H ^a,b,d   Devaux, C ^a   Sabatier, J M ^a,b   Guieu, R ^a,b,d  

^a CNRS   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

^c HÔPITAL DE LA CONCEPTION   (France)

^d TIMONE HOSPITAL   (France)

Author keywords

Adenosine; Antinociception; Kv channels; SKCa channels

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2A RECEPTOR AGONIST; ANALGESIC AGENT; APAMIN; CALCIUM ACTIVATED POTASSIUM CHANNEL; KALIOTOXIN; LEI DAB7; POTASSIUM CHANNEL BLOCKING AGENT; SCORPION VENOM; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; HOT PLATE TEST; MALE; MOUSE; NONHUMAN; POTASSIUM CONDUCTANCE;

ADENOSINE; ANALGESICS; ANIMALS; APAMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ANTAGONISM; DRUG THERAPY, COMBINATION; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; MICE, INBRED C57BL; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; PHENETHYLAMINES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; POTASSIUM CHANNELS, VOLTAGE-GATED; RECEPTORS, ADENOSINE A2; SCORPION VENOMS;

SCORPIONES;

EID: 7644243286     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.06.023     Document Type: Article

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