Intracerebral transportation and cellular localisation of insulin-like growth factor-1 following central administration to rats with hypoxic-ischemic brain injury

Brain Research

Volumn 853, Issue 2, 2000, Pages 163-173

  Guan, Jian ^a   Beilharz, Erica J ^a   Skinner, Stephen J M ^a   Williams, Chris E ^a   Gluckman, Peter D ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Apoptosis; Brain; IGF 1; Intracerebroventricular infusion; Ischemia; Translocation

Indexed keywords

RECOMBINANT SOMATOMEDIN C; SOMATOMEDIN BINDING PROTEIN; TRITIUM;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN CORTEX; BRAIN INJURY; BRAIN REGION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORPUS STRIATUM; DENTATE GYRUS; DRUG DISTRIBUTION; GLIA CELL; HIPPOCAMPUS; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; ISOTOPE LABELING; MALE; NERVE CELL; NONHUMAN; PIA MATER; PRIORITY JOURNAL; RAT; THALAMUS; WHITE MATTER;

ANIMALS; AUTORADIOGRAPHY; BIOLOGICAL TRANSPORT; BRAIN; HYPOXIA-ISCHEMIA, BRAIN; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENTRICULAR; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; INSULIN-LIKE GROWTH FACTOR I; MALE; NEURONS; RATS; RATS, WISTAR; TISSUE DISTRIBUTION; TRITIUM;

EID: 0033988001     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02030-2     Document Type: Article

References (34)

1. Araujo D.M., Lapchak P.A., Collier B., Chabot J.-G. Insulin-like growth factor 1(somatomedin-C) receptors in the rat brain: distribution and interaction with the hippocampal cholinergic system. Brain Res. 484:1989;130-138.
2. Bergstedt K., Wieloch T. Changes in insulin-like growth factor 1 receptor density after transient cerebral ischemia in the rat. Lack of protection against ischemic brain damage following injection of insulin-like growth factor 1. J. Cereb. Blood Flow Metab. 13:1993;895-898.
3. Bjelke B., England R., Nicholson C., Rice M.E. Long distance pathways of diffusion for dextran along fibre bundles in brain. Relevance for volume transmission. NeuroReport. 6:1995;1005-1009.
4. Bohannon N.J., Corp E.S., Wilcox B.J., Figlewicz D.P. Localization of binding sites for insulin-like growth factor-1 (IGF-1) in the rat brain by quantitative autoradiography. Brain Res. 444:1988;205-213.
5. Breier B.H., Gallaher B.W., Gluckman P.D. Radioimmunoassay for insulin-like growth factor-I: solutions to some potential problems and pitfalls. J. Endocrinol. 128:1991;347-357.
6. Clark R.G., Mortensen D., Reifsynder D., Mohler M. Recombinant human insulin-like growth factor binding protein-3 (rhIGFBP-3) - effects on the glycemic and growth promoting activities of rhIGF-1 in the rat. Growth Regul. 3:1993;50-52.
7. Dragunow M., Young D., Hughes P., Macgibbon G. Is c-Jun involved in nerve cell death following status epilepticus and hypoxic-ischaemic brain injury? Mol. Brain Res. 18:1993;347-352.
8. Ferguson I.A., Schweitzer J.B., Bartlett P.F., Johnson E.M. Jr. Receptor-mediated retrograde transport in CNS neurons after intraventricular administration of NGF and growth factors. J. Comp. Neurol. 313:1991;680-692.
9. Galli C., Meucci O., Scorziello A., Werge T.M. Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. J. Neurosci. 15:1995;1172-1179.
10. J. Guan, Insulin-like growth factor-1 after hypoxic-ischemic brain injury: effects and modes of action on neuronal rescue, PhD thesis, Auckland University, Auckland, 1996.
11. Guan J., Skinner S.J.M., Beilharz E.J., Hua K.M. The movement of IGF-1 into the brain parenchyma after hypoxic-ischemic injury. NeuroReport. 7:1996;632-636.
12. Guan J., Waldvogel H.J., Faull R.L.M., Gluckman P.D. The effects of the N-terminal tripeptide of insulin-like growth factor-1, glycine-proline-glutamate in different regions following hypoxic-ischemic brain injury in adult rats. Neuroscience. 89:1999;649-659.
13. Guan J., Williams C.E., Gunning M., Mallard E.C. The effects of IGF-1 treatment after hypoxic-ischemic brain injury in adult rats. J. Cereb. Blood Flow Metab. 13:1993;609-616.
14. Guan J., Williams C.E., Skinner S.J.M., Mallard E.C. The effects of insulin-like growth factor (IGF)-1, IGF-2, and Des-IGF-1 on neuronal loss after hypoxic-ischemic brain injury in adult rats - evidence for a role for IGF binding proteins. Endocrinology. 137:1996;893-898.
15. Hamon G.A., Hunt T.K., Spencer E.M. In vivo effects of systemic insulin-like growth factor-I alone and complexed with insulin-like growth factor binding protein-3 on corticosteroid suppressed wounds. Growth Regul. 3:1993;53-56.
16. Han V.K., Lu F., Bassett N.S., Yang K.P. Insulin-like growth factor-II (IGF-II) messenger ribonucleic acid is expressed in steroidogenic cells of the developing ovine adrenal gland: evidence of an autocrine/paracrine role for IGF-II. Endocrinology. 131:1992;3100-3109.
17. Ikeda T., Waldbillig R.J., Puro D.G. Truncation of IGF-I yields two mitogens for retinal Muller glial cells. Brain Res. 686:1995;87-92.
18. Johnston B.M., Mallard E.C., Williams C.E., Gluckman P.D. Insulin-like growth factor-1 is a potent neuronal rescue agent following hypoxic-ischemic injury in fetal lambs. J. Clin. Invest. 97:1996;300-308.
19. Klempt N.D., Klempt M., Gunn A.J., Singh K. Expression of insulin-like growth factor binding protein-2 (IGFBP-2) following transient hypoxia-ischemia in the infant rat brain. Brain Res. 15:1992;55-61.
20. Lesniak M.A., Hill J.M., Kiess W., Rojeski M. Receptors for insulin-like growth factors I and II: autoradiographic localization in rat brain and comparison to receptors for insulin. Endocrinology. 123:1988;2089-2099.
21. Logan A., Gonzalez A.M., Hill D.J., Berry M. Coordinated pattern of expression and localization of insulin-like growth factor-II (IGF-II) and IGF-binding protein-2 in the adult rat brain. Endocrinology. 135:1994;2255-2264.
22. Neff N.T., Prevette D., Houenou L.J., Lewis M.E. Insulin-like growth factors: putative muscle-derived trophic agents that promote motoneuron survival. J. Neurobiol. 24:1993;1578-1588.
23. Nilsson-Håkansson L., Civalero I., Zhang X., Carlsson-Skwirut C. Effects of IGF-1, truncated IGF-1 and the tripeptide Gly-Pro-Glu on acetylcholine release from parietal cortex of rat brain. NeuroReport. 4:1993;1111-1114.
24. W.M. Partridge, Transnasal and intraventricular delivery of drugs, in: Peptide Drug Delivery to the Brain, Raven Press, New York, 1991, pp. 99-121.
25. Rennels M.L., Blaumanis O.R., Grady P.A. Rapid solute transport throughout the brain via paravascular fluid pathways. Adv. Neurol. 52:1990;431-439.
26. Rennels M.L., Gregory T., Blaumanis O.R., Fujimoto K. Evidence for a "paravascular" fluid circulation in the mammalian central nervous system, provided by the rapid distribution of tracer protein throughout the brain from the subarachnoid space. Brain Res. 326:1985;47-63.
27. Resnicoff M., Abraham D., Yutanawiboonchai W., Rotman H.L. The insulin-like growth factor 1 receptor protects tumor cells from apoptosis in vivo. Cancer Res. 55:1995;2463-2469.
28. Rodriguez-Tarduchy G., Collins M.K.L., Garcia I., Lopez-Rivas A. Insulin-like growth factor-1 inhibits apoptosis in IL-3-dependent hemopoietic cells. J. Immunol. 149:1992;535-540.
29. Sara V.R., Carlsson-Sdwirut C., Bergman T., Jornvall H. Identification of Gly-Pre-Glu (GPE), the aminoterminal tripeptide of insulin-like growth factor 1 which is truncated in brain, as a novel neuroaction peptide. Biochem. Biophys. Res. Commun. 165:1989;766-771.
30. Saura J., Curatolo L., Williams C., Gatti C. Neuroprotective effects of Gly-Pro-Glu, the N-terminal tripeptide of IGF-1 in the hippocampus in vitro. NeuroReport. 10:1999;161-164.
31. Schwartzman R.A., Cidlowski J.A. Apoptosis: the biochemistry and molecular biology of programmed cell death. Endocr. Rev. 14:1993;133-151.
32. Tamm I., Kikuchi T. Insulin-like growth factor-1 (IGF-1), insulin, and epidermal growth factor (EGF) are survival factors for density-inhibited, quiescent Balb/c-3T3 murine fibroblasts. J. Cell. Physiol. 143:1990;494-500.
33. Yamamoto H., Murphy L.J. Enzymatic conversion of IGF-I to des(1-3)IGF-I in rat serum and tissues: a further potential site of growth hormone regulation of IGF-I action. J. Endocrinol. 146:1995;141-148.
34. Zhu C.Z., Auer R.N. Intraventricular administration of insulin and IGF-1 in transient forebrain ischemia. J. Cereb. Blood Flow Metab. 14:1994;237-242.