-
1
-
-
0034326706
-
The role of chemokines and chemokine receptors in mucosal inflammation
-
Papadakis KA, Targan SR. The role of chemokines and chemokine receptors in mucosal inflammation. Inflamm Bowel Dis. 2000, 6:303-13.
-
(2000)
Inflamm Bowel Dis.
, vol.6
, pp. 303-313
-
-
Papadakis, K.A.1
Targan, S.R.2
-
2
-
-
34147126829
-
The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk
-
Popa C, Netea MG, Van Riel PL. The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk. J Lipid Res. 2007, 48:751-62.
-
(2007)
J Lipid Res.
, vol.48
, pp. 751-762
-
-
Popa, C.1
Netea, M.G.2
Van Riel, P.L.3
-
3
-
-
0033168031
-
Therapeutic potential and strategies for inhibiting tumor necrosis factor-alpha
-
Newton RC, Decicco CP. Therapeutic potential and strategies for inhibiting tumor necrosis factor-alpha. J Med Chem. 1999, 42:2295-314.
-
(1999)
J Med Chem.
, vol.42
, pp. 2295-2314
-
-
Newton, R.C.1
Decicco, C.P.2
-
5
-
-
0029047933
-
Inhibition of tumor necrosis factor by curcumin, a phytochemical
-
Chan MM. Inhibition of tumor necrosis factor by curcumin, a phytochemical. Biochem Pharmacol. 1995, 49:1551-6.
-
(1995)
Biochem Pharmacol.
, vol.49
, pp. 1551-1556
-
-
Chan, M.M.1
-
6
-
-
33947532054
-
Curcumin attenuates the expression of IL-1beta, IL-6, and TNF-alpha as well as cyclin E in TNF-alpha-treated HaCaT cells; NF-kappaB and MAPKs as potential upstream targets
-
Cho JW, Lee KS, Kim CW. Curcumin attenuates the expression of IL-1beta, IL-6, and TNF-alpha as well as cyclin E in TNF-alpha-treated HaCaT cells; NF-kappaB and MAPKs as potential upstream targets. Int J Mol Med. 2007, 19:469-74.
-
(2007)
Int J Mol Med.
, vol.19
, pp. 469-474
-
-
Cho, J.W.1
Lee, K.S.2
Kim, C.W.3
-
7
-
-
0035997266
-
Relative contribution of NF-kappaB and AP-1 in the modulation by curcumin and pyrrolidine dithiocarbamate of the UVB-induced cytokine expression by keratinocytes
-
Grandjean-Laquerriere A, Gangloff SC, Le Naour R. Relative contribution of NF-kappaB and AP-1 in the modulation by curcumin and pyrrolidine dithiocarbamate of the UVB-induced cytokine expression by keratinocytes. Cytokine 2002, 18:168-77.
-
(2002)
Cytokine
, vol.18
, pp. 168-177
-
-
Grandjean-Laquerriere, A.1
Gangloff, S.C.2
Le, N.R.3
-
8
-
-
42949162968
-
Heme oxygenase-1 mediates the anti-inflammatory effect of curcumin within LPS-stimulated human monocytes
-
Hsu HY, Chu LC, Hua KF. Heme oxygenase-1 mediates the anti-inflammatory effect of curcumin within LPS-stimulated human monocytes. J Cell Physiol. 2008, 215:603-12.
-
(2008)
J Cell Physiol.
, vol.215
, pp. 603-612
-
-
Hsu, H.Y.1
Chu, L.C.2
Hua, K.F.3
-
9
-
-
0033429405
-
Inhibition of interleukin-12 production in lipopolysaccharide-activated macrophages by curcumin
-
Kang BY, Kang BY, Chung SW. Inhibition of interleukin-12 production in lipopolysaccharide-activated macrophages by curcumin. Eur J Pharmacol. 1999, 384:191-5.
-
(1999)
Eur J Pharmacol.
, vol.384
, pp. 191-195
-
-
Kang, B.Y.1
Kang, B.Y.2
Chung, S.W.3
-
10
-
-
84934444244
-
Clinical studies with curcumin
-
Hsu CH, Cheng AL. Clinical studies with curcumin. Adv Exp Med Biol. 2007, 595:471-80.
-
(2007)
Adv Exp Med Biol.
, vol.595
, pp. 471-480
-
-
Hsu, C.H.1
Cheng, A.L.2
-
11
-
-
0030322880
-
Clinical development plan: curcumin
-
S, NCI, DCPC
-
Clinical development plan: curcumin. J Cell Biochem. 1996, 26S:72-85. NCI, DCPC
-
(1996)
J Cell Biochem.
, vol.26
, pp. 72-85
-
-
-
13
-
-
0034772953
-
Pharmacodynamic and pharmacokinetic study of oral curcuma extract in patients with colorectal cancer
-
Sharma RA, McLelland HR, Hill KA. Pharmacodynamic and pharmacokinetic study of oral curcuma extract in patients with colorectal cancer. Clin Cancer Res. 2001, 7:1894-900.
-
(2001)
Clin Cancer Res.
, vol.7
, pp. 1894-1900
-
-
Sharma, R.A.1
McLelland, H.R.2
Hill, K.A.3
-
14
-
-
51649118928
-
Phase II trial of curcumin in patients with advanced pancreatic cancer
-
Dhillon B, Aggarwal BB, Newman RA. Phase II trial of curcumin in patients with advanced pancreatic cancer. Clin Cancer Res. 2008, 14:4491-9.
-
(2008)
Clin Cancer Res.
, vol.14
, pp. 4491-4499
-
-
Dhillon, B.1
Aggarwal, B.B.2
Newman, R.A.3
-
15
-
-
1542286600
-
Enzymology of a carbonyl reduction clearance pathway for the HIV integrase inhibitor, S-1360: role of human liver cytosolic aldo-keto reductases
-
Rosemond MJ, St John-Williams L, Yamaguchi T. Enzymology of a carbonyl reduction clearance pathway for the HIV integrase inhibitor, S-1360: role of human liver cytosolic aldo-keto reductases. Chem Biol Interact. 2004, 147:129-39.
-
(2004)
Chem Biol Interact.
, vol.147
, pp. 129-139
-
-
Rosemond, M.J.1
St John-Williams, L.2
Yamaguchi, T.3
-
16
-
-
21744450137
-
Emergent mechanistic diversity of enzyme-catalysed beta-diketone cleavage
-
Grogan G. Emergent mechanistic diversity of enzyme-catalysed beta-diketone cleavage. Biochem J. 2005, 388:721-30.
-
(2005)
Biochem J.
, vol.388
, pp. 721-730
-
-
Grogan, G.1
-
17
-
-
38849154619
-
Synthesis and anti-bacterial properties of mono-carbonyl analogues of curcumin
-
Liang G, Yang S, Jiang L. Synthesis and anti-bacterial properties of mono-carbonyl analogues of curcumin. Chem Pharm Bull. 2008, 56:162-7.
-
(2008)
Chem Pharm Bull.
, vol.56
, pp. 162-167
-
-
Liang, G.1
Yang, S.2
Jiang, L.3
-
18
-
-
38949090015
-
Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin
-
Liang G, Li X, Chen L. Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin. Bioorg Med Chem Lett. 2008, 18:1525-9.
-
(2008)
Bioorg Med Chem Lett.
, vol.18
, pp. 1525-1529
-
-
Liang, G.1
Li, X.2
Chen, L.3
-
19
-
-
62149086696
-
Exploration and synthesis of curcumin analogues with improved structural stability as anti-tumor agents
-
doi
-
Liang G, Shao L, Wang Y. Exploration and synthesis of curcumin analogues with improved structural stability as anti-tumor agents. Bioorg Med Lett 2008, 10.1016/j.bmc.2008.10.044, doi
-
(2008)
Bioorg Med Lett
-
-
Liang, G.1
Shao, L.2
Wang, Y.3
-
20
-
-
17744371331
-
TNF-a induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway
-
Dumitru CD, Ceci JD, Tsatsanis C. TNF-a induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway. Cell. 2000, 103:1071-83.
-
(2000)
Cell.
, vol.103
, pp. 1071-1083
-
-
Dumitru, C.D.1
Ceci, J.D.2
Tsatsanis, C.3
-
21
-
-
33750627921
-
The dynamics of the LPS triggered inflammatory response of murine microglia under different culture and in vivo conditions
-
Lund S, Christensen KV, Hedtjärn M. The dynamics of the LPS triggered inflammatory response of murine microglia under different culture and in vivo conditions. J Neuroimmunol. 2006, 180:71-87.
-
(2006)
J Neuroimmunol.
, vol.180
, pp. 71-87
-
-
Lund, S.1
Christensen, K.V.2
Hedtjärn, M.3
-
22
-
-
24944565385
-
Pharmacological intervention of cyclooxygenase-2 and 5-lipoxygenase pathways. Impact on inflammation and cancer
-
Claria J, Romano M. Pharmacological intervention of cyclooxygenase-2 and 5-lipoxygenase pathways. Impact on inflammation and cancer. Curr Pharm Des. 2005, 11:3431-47.
-
(2005)
Curr Pharm Des.
, vol.11
, pp. 3431-3447
-
-
Claria, J.1
Romano, M.2
-
23
-
-
4043088499
-
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated, cancer
-
Greten FR, Eckmann L, Greten TF. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated, cancer. Cell 2004, 118:285-96.
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
-
24
-
-
0036546501
-
NF-kappaB in cancer: from innocent bystander to major culprit
-
Karin M, Cao Y, Greten FR. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002, 2:301-15.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 301-315
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
-
25
-
-
0035451363
-
Molecular mechanisms underlying chemopreventive activities of anti-inflamatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation
-
Surh YJ, Chun KS, Cha HH. Molecular mechanisms underlying chemopreventive activities of anti-inflamatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutat Res. 2001, 480:243-68.
-
(2001)
Mutat Res.
, vol.480
, pp. 243-268
-
-
Surh, Y.J.1
Chun, K.S.2
Cha, H.H.3
-
26
-
-
0034578521
-
Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages
-
Pan MH, Lin-Shiau SY, Lin JK. Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages. Biochem Pharmacol. 2000, 60:1665-76.
-
(2000)
Biochem Pharmacol.
, vol.60
, pp. 1665-1676
-
-
Pan, M.H.1
Lin-Shiau, S.Y.2
Lin, J.K.3
-
27
-
-
36749085341
-
Cyclooxygenase-2 (COX-2)-a therapeutic target in liver cancer
-
Breinig M, Schirmacher P, Kern MA. Cyclooxygenase-2 (COX-2)-a therapeutic target in liver cancer. Curr Pharm Des. 2007, 13:3305-15.
-
(2007)
Curr Pharm Des.
, vol.13
, pp. 3305-3315
-
-
Breinig, M.1
Schirmacher, P.2
Kern, M.A.3
-
28
-
-
0345505237
-
Cyclooxygenase-2 and prostate carcinogenesis
-
Hussain T, Gupta S, Mukhtar H. Cyclooxygenase-2 and prostate carcinogenesis. Cancer Lett. 2003, 191:125-35.
-
(2003)
Cancer Lett.
, vol.191
, pp. 125-135
-
-
Hussain, T.1
Gupta, S.2
Mukhtar, H.3
-
29
-
-
33745642485
-
Antitumor agents. 250. Design and synthesis of new curcumin analogues as potential anti-prostate cancer agents
-
Lin L, Shi Q, Nyarko AK. Antitumor agents. 250. Design and synthesis of new curcumin analogues as potential anti-prostate cancer agents. J Med Chem. 2006, 49:3963-72.
-
(2006)
J Med Chem.
, vol.49
, pp. 3963-3972
-
-
Lin, L.1
Shi, Q.2
Nyarko, A.K.3
-
30
-
-
15044362170
-
Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents
-
Selvam C, Jachak SM, Thilagavathi R. Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents. Bioorg Med Chem Lett. 2005, 15:1793-7.
-
(2005)
Bioorg Med Chem Lett.
, vol.15
, pp. 1793-1797
-
-
Selvam, C.1
Jachak, S.M.2
Thilagavathi, R.3
-
31
-
-
33748744148
-
Novel curcumin analogs targeting TNF-induced NF-jB activation and proliferation in human leukemic KBM-5 cells
-
Zambre AP, Kulkarni VM, Padhye S. Novel curcumin analogs targeting TNF-induced NF-jB activation and proliferation in human leukemic KBM-5 cells. Bioorg Med Chem. 2006, 14:7196-204.
-
(2006)
Bioorg Med Chem.
, vol.14
, pp. 7196-7204
-
-
Zambre, A.P.1
Kulkarni, V.M.2
Padhye, S.3
-
32
-
-
33746197963
-
Multiple molecular targets in cancer chemoprevention by curcumin
-
Thangapazham RL, Sharma A, Maheshwari RK. Multiple molecular targets in cancer chemoprevention by curcumin. AAPS J 2006, 8:E443-9.
-
(2006)
AAPS J
, vol.8
-
-
Thangapazham, R.L.1
Sharma, A.2
Maheshwari, R.K.3
-
33
-
-
4344694589
-
Abnormal solvent effects on hydrogen atom abstraction: resolution of the curcumin antioxidant controversy. The role of sequential proton loss electron transfer
-
Litwinienko G, Ingold KU. Abnormal solvent effects on hydrogen atom abstraction: resolution of the curcumin antioxidant controversy. The role of sequential proton loss electron transfer. J Org Chem. 2004, 69:5888-96.
-
(2004)
J Org Chem.
, vol.69
, pp. 5888-5896
-
-
Litwinienko, G.1
Ingold, K.U.2
-
34
-
-
0034618287
-
On the antioxidant mechanism of curcumin: classical methods are needed to determine antioxidant mechanism and activity
-
Barclay LRC, Vinqvist MR. On the antioxidant mechanism of curcumin: classical methods are needed to determine antioxidant mechanism and activity. Org Lett. 2000, 2:2841-3.
-
(2000)
Org Lett.
, vol.2
, pp. 2841-2843
-
-
Barclay, L.R.C.1
Vinqvist, M.R.2
-
35
-
-
0034823149
-
How curcumin works preferentially with water soluble antioxidants
-
Jovanovic SV, Boone CW, Steenken S. How curcumin works preferentially with water soluble antioxidants. J Am Chem Soc. 2001, 123:3064-8.
-
(2001)
J Am Chem Soc.
, vol.123
, pp. 3064-3068
-
-
Jovanovic, S.V.1
Boone, C.W.2
Steenken, S.3
-
36
-
-
27144503124
-
Curcumin suppresses interleukin 1β-mediated microtonal prostaglandin E syntheses 1 by altering early growth response gene 1 and other signaling pathways
-
Moon Y, Glasgow WC, Eling TE. Curcumin suppresses interleukin 1β-mediated microtonal prostaglandin E syntheses 1 by altering early growth response gene 1 and other signaling pathways. J Pharmacol Exp Ther. 2005, 315:788-95.
-
(2005)
J Pharmacol Exp Ther.
, vol.315
, pp. 788-795
-
-
Moon, Y.1
Glasgow, W.C.2
Eling, T.E.3
-
37
-
-
0032525741
-
In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties
-
Chan MM, Huang HI, Fenton MR. In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties. Biochem Pharmacol. 1998, 55:1955-62.
-
(1998)
Biochem Pharmacol.
, vol.55
, pp. 1955-1962
-
-
Chan, M.M.1
Huang, H.I.2
Fenton, M.R.3
|