Gases in the mitochondria

Mitochondrion

Volumn 10, Issue 2, 2010, Pages 83-93

  Pun, Pamela B L ^a   Lu, Jia ^a   Kan, Enci M ^a   Moochhala, Shabbir ^a  

^a DSO NATIONAL LABORATORIES   (Singapore)

Author keywords

Carbon monoxide; Gasomodulators; Hydrogen sulphide; Mitochondria; Nitric oxide

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARBON MONOXIDE; CYTOCHROME C OXIDASE; HYDROGEN SULFIDE; MITOCHONDRIAL DNA; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; BINDING COMPETITION; BIOGENESIS; BIOLOGICAL ACTIVITY; CELL DEATH; CELL PROTECTION; CHEMICAL INTERACTION; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENERGY YIELD; ENZYME ACTIVITY; ENZYME INHIBITION; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RESPIRATORY CHAIN; REVIEW; SIGNAL TRANSDUCTION;

CARBON MONOXIDE; HYDROGEN SULFIDE; MITOCHONDRIA; NITRIC OXIDE;

EID: 76049130069     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2009.12.142     Document Type: Review

References (165)

1. 2S-induced pancreatic acinar cell apoptosis is mediated via JNK and p38 MAP kinase. J. Cell Mol. Med. 12 (2008) 1374-1383
2. Alarie Y. Toxicity of fire smoke. Crit. Rev. Toxicol. 32 (2002) 259-289
3. Almeida A., Almeida J., Bolanos J.P., and Moncada S. Different responses of astrocytes and neurons to nitric oxide: the role of glycolytically generated ATP in astrocyte protection. Proc. Natl. Acad. Sci. USA 98 (2001) 15294-15299
4. Almeida A., Cidad P., Delgado-Esteban M., Fernandez E., Garcia-Nogales P., and Bolanos J.P. Inhibition of mitochondrial respiration by nitric oxide: its role in glucose metabolism and neuroprotection. J. Neurosci. Res. 79 (2005) 166-171
5. Alonso J.R., Cardellach F., Lopez S., Casademont J., and Miro O. Carbon monoxide specifically inhibits cytochrome c oxidase of human mitochondrial respiratory chain. Pharmacol. Toxicol. 93 (2003) 142-146
6. Bal-Price A., and Brown G.C. Nitric oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria. J. Neurochem. 75 (2000) 1455-1464
7. Baskar R., Li L., and Moore P.K. Hydrogen sulphide-induces DNA damage and changes in apoptotic gene expression in human lung fibroblast cells. FASEB J. 21 (2007) 247-255
8. Baumgart K., Radermacher P., and Wagner F. Applying gases for microcirculatory and cellular oxygenation in sepsis: effects of nitric oxide, carbon monoxide and hydrogen sulphide. Curr. Opin. Anaesthesiol. 22 (2009) 168-176
9. Beal M.F. Mitochondria and neurodegeneration. Novartis Found. Symp. 287 (2007) 183-192
10. Bilban M., Bach F.H., Otterbein S.L., Ifedigbo E., d'Avila J.C., Esterbauer H., Chin B.Y., Usheva A., Robson S.C., Wagner O., and Otterbein L.E. Carbon monoxide orchestrates a protective response through PPARgamma. Immunity 24 (2006) 601-610
11. Bilban M., Haschemi A., Wegiel B., Chin B.Y., Wagner O., and Otterbein L.E. Heme oxygenase and carbon monoxide initiate homeostatic signalling. J. Mol. Med. 86 (2008) 267-279
12. Bolanos J.P., and Almeida A. Modulation of astroglial energy metabolism by nitric oxide. Antioxid. Redox Signal. 8 (2006) 955-965
13. Bolanos J.P., Heales S.J., Land J.M., and Clark J.B. Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture. J. Neurochem. 64 (1995) 1965-1972
14. Bolanos J.P., Heales S.J., Peuchen S., Barker J.E., Land J.M., and Clark J.B. Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione. Free Radical Biol. Med. 21 (1996) 995-1001
15. Borutaite V., and Brown G.C. Nitric oxide induces apoptosis via hydrogen peroxide, but necrosis via energy and thiol depletion. Free Radical Biol. Med. 35 (2003) 1457-1468
16. Bouton C., and Demple B. Nitric oxide-inducible expression of heme oxygenase-1 in human cells. Translation independent stabilization of the mRNA and evidence for direct action of nitric oxide. J. Biol. Chem. 275 (2000) 32688-32693
17. Brouard S., Berberat P.O., Tobiash E., Seldon M.P., Bach F.H., and Soares M.P. Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumour necrosis factor-alpha-mediated apoptosis. J. Biol. Chem. 277 (2002) 17950-17961
18. Brown G.C. Nitric oxide and mitochondrial respiration. Biochim. Biophys. Acta 1411 (1999) 351-369
19. Brown G.C., and Borutaite V. Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols. Biochim. Biophys. Acta 1658 (2004) 44-49
20. Brown G.C., and Cooper C.E. Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase. FEBS Lett. 356 (1994) 295-298
21. Brown S.D., and Piantadosi C.A. Recovery of energy metabolism in rat brain after carbon monoxide hypoxia. J. Clin. Invest. 89 (1992) 666-672
22. Calabrese V., Mancuso C., Calvani M., Rizzarelli E., Butterfield D.A., and Stella A.M. Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity. Nat. Rev. Neurosci. 8 (2007) 766-775
23. Carreras M.C., Peralta J.G., Converso D.P., Finocchietto P.V., Rebagliati I., Zaninovich A.A., and Poderoso J.J. Modulation of liver mitochondrial NOS is implicated in thyroid-dependent regulation of O(2) uptake. Am. J. Physiol. Heart Circ. Physiol. 281 (2001) H2282-H2288
24. Carreras M.C., Franco M.C., Molinas M.F., Gonzalez A.S., Serra M.P., Finocchietto P.V., Converso D.P., and Poderoso J.J. O18 Neuronal nitric oxide synthase trafficking into mitochondria involves the processing of the PDZ domain. Nitric Oxide 19 (2008) 24
25. Cassina A., and Radi R. Differential inhibitory action of nitric oxide and peroxynitrite on mitochondrial electron transport. Arch. Biochem. Biophys. 328 (1996) 309-316
26. Castro L., Rodriguez M., and Radi R. Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide. J. Biol. Chem. 269 (1994) 29409-29415
27. Cheng A., Chan S.L., Milhavet O., Wang S., and Mattson M.P. P38 MAP kinase mediates nitric oxide-induced apoptosis of neural progenitor cells. J. Biol. Chem. 276 (2001) 43320-43327
28. Choi B.M., Pae H.O., Jang S.I., Kim Y.M., and Chung H.T. Nitric oxide as a pro-apoptotic as well as anti-apoptotic modulator. J. Biochem. Mol. Biol. 35 (2002) 116-126
29. Cidad P., Almeida A., and Bolanos J.P. Inhibition of mitochondrial respiration by nitric oxide rapidly stimulates cytoprotective GLUT3-mediated glucose uptake through 5′-AMP-activated protein kinase. Biochem. J. 384 (2004) 629-636
30. Cleeter M.W., Cooper J.M., Darley-Usmar V.M., Moncada S., and Schapira A.H. Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases. FEBS Lett. 345 (1994) 50-54
31. Clementi E., and Nisoli E. Nitric oxide and mitochondrial biogenesis: a key to long-term regulation of cellular metabolism. Comp. Biochem. Physiol. 142 (2005) 102-110
32. Converso D.P., Taille C., Carreras M.C., Jaitovich A., Ponderoso J.J., and Boczkowski J. HO-1 is located in liver mitochondria and modulates mitochondrial heme content and metabolism. FASEB J. 20 (2006) 1236-1238
33. Cooper C.E., and Brown G.C. The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulphide: chemical mechanism and physiological significance. J. Bioenerg. Biomembr. 40 (2008) 533-539
34. Cooper C.E., and Giulivi C. Nitric oxide regulation of mitochondrial oxygen consumption II: molecular mechanism and tissue physiology. Am. J. Physiol. Cell Physiol. 292 (2007) C1993-C2003
35. Cooper C.E., Torres J., Sharpe M.A., and Wilson M.T. Nitric oxide ejects electrons from the binuclear centre of cytochrome c oxidase by reacting with oxidized copper: a general mechanism for the interaction of copper proteins with nitric oxide?. FEBS Lett. 414 (1997) 281-284
36. Crawford D.R., Wang Y., Schools G.P., Kochheiser J., and Davies K.J.A. Down-regulation of mammalian mitochondrial RNAs during oxidative stress. Free Radical Biol. Med. 22 (1997) 551-559
37. D'Amico G., Lam F., Hagan T., and Moncada S. Inhibition of cellular respiration by endogenously produced carbon monoxide. J. Cell Sci. 119 (2006) 2291-2298
38. Datta P.K., and Lianos E.A. Nitric oxide induces heme oxygenase-1 gene expression in mesangial cells. Kidney Int. 55 (1999) 1734-1739
39. Decoster E., Simon M., Hatat D., and Faye G. The MSS51 gene product is required for the translation of the COX1 mRNA in yeast mitochondria. Mol. Gen. Genet. 224 (1990) 111-118
40. Deng M., Zhao J.Y., and Fan D.S. Effects of exogenous carbon monoxide on neurocytes: experiment in vitro. Zhonghua Yi Xue Za Zhi 88 (2008) 3085-3089
41. Dhakshinamoorthy S., and Porter A.G. Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells. J. Biol. Chem. 279 (2004) 20096-20107
42. Di Lisa F., Kaludercic N., Carpi A., Menabo R., and Giorgio M. Mitochondrial pathways for ROS formation, myocardial injury: the relevance of p66(Shc), monoamine oxidase. Basic Res. Cardiol. 104 (2009) 131-139
43. Dorman D.C., Moulin F.J.M., McManus B.E., Mahle K.C., James R.A., and Struve M.F. Cytochrome oxidase inhibition induced by acute hydrogen sulphide inhalation: correlation with tissue sulphide concentrations in the rat brain, liver, lung and nasal epithelium. Toxicol. Sci. 65 (2002) 18-25
44. Durante W., Kroll M.H., Christodoulides N., Peyton K.J., and Scahfer A.I. Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells. Circ. Res. 80 (1997) 557-564
45. 2S cytotoxicity mechanism involves reactive oxygen species formation and mitochondrial depolarisation. Toxicology 203 (2004) 69-76
46. Elbirt K.K., and Bonkovsky H.L. Heme oxygenase: recent advances in understanding its regulation and role. Proc. Assoc. Am. Physicians 111 (1999) 438-447
47. Elfering S.L., Sarkela T.M., and Giulivi C. Biochemistry of mitochondrial nitric-oxide synthase. J. Biol. Chem. 277 (2002) 38079-38086
48. Exline M.C., and Crouser E.D. Mitochondrial mechanisms of sepsis-induced organ failure. Front Biosci. 13 (2008) 5030-5041
49. Finocchietto P.V., Franco M.C., Holod S., Gonzalez A.S., Converso D.P., Arciuch V.G.A., Serra M.P., Ponderoso J.J., and Carreras M.C. Mitochodnrial nitric oxide synthase: a masterpiece of metabolic adaptation, cell growth, transformation, and death. Exp. Biol. Med. 234 (2009) 1020-1028
50. Foresti R., Green C.J., and Motterlini R. Generation of bile pigments by haem oxygenase: a refined cellular strategy in response to stressful insults. Biochem. Soc. Symp. 71 (2004) 177-192
51. Frankel D., Mehindate K., and Schipper H.M. Role of heme oxygenase-1 in the regulation of manganese superoxide dismutase gene expression in oxidatively-challenged astroglia. J. Cell Physiol. 185 (2000) 80-86
52. Fukuto J.M., and Collins M.D. Interactive endogenous small molecule (gaseous) signalling: implications for teratogenesis. Curr. Pharm. Des. 13 (2007) 2952-2978
53. Garcia-Nogales P., Almeida A., and Bolanos J.P. Peroxynitrite protects neurons against nitric oxide-mediated apoptosis. A key role for glucose-6-phosphate dehydrogenase activity in neuroprotection. J. Biol. Chem. 278 (2003) 864-874
54. Ghafourifar P., and Richter C. Nitric oxide synthase activity in mitochondria. FEBS Lett. 418 (1997) 291-296
55. Ghafourifar P., and Richter C. Mitochondrial nitric oxide synthase regulates mitochondrial matrix pH. Biol. Chem. 380 (1999) 1025-1028
56. Ghatan S., Larner S., Kinoshita Y., Hetman M., Patel L., Xia Z., Youle R.J., and Morrison R.S. P38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons. J. Cell Biol. 150 (2000) 335-347
57. Giulivi C., Poderoso J.J., and Boveris A. Production of nitric oxide by mitochondria. J. Biol. Chem. 273 (1998) 11038-11043
58. Goubern M., Andriamihaja M., Nubel T., Blachier F., and Bouillaud F. Sulfide, the first inorganic substrate for human cells. FASEB J. 21 (2007) 1699-1706
59. Guo F.Q., and Crawford N.M. Arabidopsis nitric oxide synthase1 is targeted to mitochondria and protects against oxidative damage and dark-induced senescence. Plant Cell. 17 (2005) 3436-3450
60. Guo F.Q., Okamoto M., and Crawford N.M. Identification of a plant nitric oxide synthase gene involved in hormonal signaling. Science 302 (2003) 100-103
61. Hildebrandt T.M., and Grieshaber M.K. Redox regulation of mitochondrial sulphide oxidation in the lugworm, Arenicola marina. J. Exp. Biol. 211 (2008) 2617-2623
62. Hortelano S., Dallaporta B., Zamzami N., Hirsch T., Susin S.A., Marzo I., Bosca L., and Kroemer G. Nitric oxide induces apoptosis via triggering mitochondrial permeability transition. FEBS Lett. 410 (1997) 373-377
63. Hu L.F., Lu M., Wu Z.Y., Wong P.T., and Bian J.S. Hydrogen sulphide inhibits rotenone-induced apoptosis via preservation of mitochondrial function. Mol. Pharmacol. 75 (2009) 27-34
64. Huang L.E., Willmore W.G., Gu J., Goldberg M.A., and Bunn H.F. Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide: implications for oxygen sensing and signalling. J. Biol. Chem. 274 (1999) 9038-9044
65. Iheagwara K.N., Thom S.R., Deutschman C.S., and Levy R.J. Myocardial cytochrome oxidase activity is decreased following carbon monoxide exposure. Biochim. Biophys. Acta 1772 (2007) 1112-1116
66. Ishigami M., Hiraki K., Umemura K., Ogasawara Y., Ishii K., and Kimura H. A source of hydrogen sulphide and a mechanism of its release in the brain. Antioxid. Redox Signal. 11 (2009) 205-214
67. Kanai A.J., Pearce L.L., Clemens P.R., Birder L.A., VanBibber M.M., Choi S.Y., de Groat W.C., and Peterson J. Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection. Proc. Natl. Acad. Sci. USA 98 (2001) 14126-14131
68. Kapetanaki S.M., Silkstone G., Husu I., Liebl U., Wilson M.T., and Vos M.H. Interaction of carbon monoxide with the apoptosis-inducing cytochrome c-cardiolipin complex. Biochemistry 48 (2009) 1613-1619
69. Kasparek M.S., Linden D.R., Kreis M.E., and Sarr M.G. Gasotransmitters in the gastrointestinal tract. Surgery 143 (2007) 455-459
70. Khan A.A., Schuler M.M., Prior M.G., Yong S., Coppock R.W., Florence L.Z., and Lillie L.E. Effects of hydrogen sulphide exposure on lung mitochondrial respiratory chain enzymes in rats. Toxicol. Appl. Pharmacol. 103 (1990) 482-490
71. Kim H.S., Loughran P.A., Kim P.K., Billiar T.R., and Zuckerbraun B.S. Carbon monoxide protects hepatocytes from TNF-alpha/actinomycin D by inhibition of the caspase-8-mediated apoptotic pathway. Biochem. Biophys. Res. Commun. 344 (2006) 1172-1178
72. Kim H.S., Loughran P.A., Rao J., Billiar T.R., and Zuckerbraun B.S. Carbon monoxide activates NF-kappa B via ROS generation and Akt pathways to protect against cell death of hepatocytes. Am. J. Physiol. Gastrointest. Liver Physiol. 295 (2008) G146-G152
73. Kimura Y., and Kimura H. Hydrogen sulphide protects neurons from oxidative stress. FASEB J. 18 (2004) 1165-1167
74. Kimura Y., Dargusch R., Schubert D., and Kimura H. Hydrogen sulphide protects HT22 neuronal cells from oxidative stress. Antioxid. Redox Signal. 8 (2006) 661-670
75. Kobzik L., Stringer B., Balligand J.L., Reid M.B., and Stamler J.S. Endothelial type nitric oxide synthase in skeletal muscle fibers: mitochondrial relationships. Biochem. Biophys. Res. Commun. 211 (1995) 375-381
76. Kohmoto J., Nakao A., Stolz D.B., Kaizu T., Tsung A., Ikeda A., Shimizu H., Takahashi T., Tomiyama K., Sugimoto R., Choi A.M., Billiar T.R., Murase N., and McCurry K.R. Carbon monoxide protects rat lung transplants from ischemia-reperfusion injury via a mechanism involving p38 MAPK pathway. Am. J. Transplant. 7 (2007) 2279-2290
77. Kovisto A., Matthias A., Bronnikov G., and Nedergaard J. Kinetics of the inhibition of mitochondrial respiration by NO. FEBS Lett. 417 (1997) 75-80
78. Kristal B.S., Koopmans S.J., Jackson C.T., Ikeno Y., Park P.-J., and Yu B.P. Oxidant-mediated repression of mitochondrial transcription in diabetic rats. Free Radical Biol. Med. 22 (1997) 813-822
79. Lancel S., Hassoun S.M., Favory R., Decoster B., Motterlini R., and Neviere R. Carbon monoxide rescues mice from lethal sepsis by supporting mitochondrial energetic metabolism and activating mitochondrial biogenesis. J. Pharmacol. Exp. Ther. 329 (2009) 641-648
80. Lavitrano M., Smolenski R.T., Musumeci A., Maccherini M., Slominska E., Di Florio E., Bracco A., Mancini A., Stassi G., Patti M., Giovannoni R., Froio A., Simeone F., Forni M., Bacci M.L., D'Alise G., Cozzi E., Otterbein L.E., Yacoub M.H., Bach F.H., and Cliase F. Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs. FASEB J. 18 (2004) 1093-1095
81. Leschelle X., Goubern M., Andriamihaja M., Blottiere H.M., Couplan E., Gonzalez-Barroso M., Petit C., Pagniez A., Chaumontet C., Mignotte B., Bouillaud F., and Blachier F. Adaptative metabolic response of human colonic epithelial cells to the adverse effects of the luminal compound sulphide. Biochim. Biophys. Acta 1725 (2005) 201-212
82. Li L., and Moore P.K. An overview of the biological significance of endogenous gases: new roles for old molecules. Biochem. Soc. Trans. 35 (2007) 1138-1141
83. Li M.H., Cha Y.N., and Surh Y.J. Carbon monoxide protects PC12 cells from peroxynitrite-induced apoptotic death by preventing the depolarization of mitochondrial transmembrane potential. Biochem. Biophys. Res. Commun. 342 (2006) 984-990
84. Li X., Du J., Jin H., Tang X., Bu D., and Tang C. The regulatory effect of endogenous hydrogen sulphide on pulmonary vascular structure and gasotransmitters in rats with high pulmonary blood flow. Life Sci. 81 (2007) 841-849
85. Li L., Hsu A., and Moore P.K. Actions and interactions of nitric oxide, carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation - a tale of three gases!. Pharmacol. Ther. (2009) 10.1016/j.pharmathera.2009.05.005
86. Lisdero C.L., Carreras M.C., Meulemans A., Melani M., Aubier M., Boczkowski J., and Poderoso J.J. The mitochondrial interplay of ubiquinol and nitric oxide in endotoxemia. Methods Enzymol. 382 (2004) 67-81
87. Liu S.H., Ma K., Xu B., and Xu X.R. The mechanisms of carbon monoxide inhalation on the apoptosis of pulmonary cells in rats with acute lung injury induced by lipopolysaccharide. Zhonghua Jie He He Hu Xi Za Zhi 29 (2006) 329-332
88. Lizasoain I., Moro M.A., Knowles R.G., Darley-Usmar V., and Moncada S. Nitric oxide and peroxynitrite exert distinct effects on mitochondrial respiration which are differentially blocked by glutathione or glucose. Biochem. J. 314 (1996) 877-880
89. Lopez L.C., Escames G., Tapias V., Utrilla P., Leon J., and Acuna-Castroviejo D. Identification of an inducible nitric oxide synthase in diaphragm mitochondria from septic mice: its relation with mitochondrial dysfunction and prevention by melatonin. Int. J. Biochem. Cell Biol. 38 (2006) 267-278
90. 2S): the third gas of interest for pharmacologists. Pharmacol. Rep. 59 (2007) 4-24
91. Manthey G.M., and McEwen J.E. The product of the nuclear gene PET309 is required for translation of mature mRNA and stability or production of intron-containing RNAs derived from the mitochondrial COX1 locus of Saccharomyces cerevisiae. EMBO J. 14 (1995) 4031-4043
92. Mason T.L., and Schatz G. Cytochrome c oxidase from bakers' yeast. II. Site of translation of the protein components. J. Biol. Chem. 248 (1973) 1355-1360
93. Mason M.G., Nicholls P., Wilson M.T., and Cooper C.E. Nitric oxide inhibition of respiration involves both competitive (heme) and non-competitive (copper) binding to cytochrome c oxidase. Proc. Natl. Acad. Sci. USA 103 (2006) 708-713
94. Matsuoka M., Igisu H., Tanaka I., Hori H., and Koga M. Brain energy metabolites in mice after an acute exposure to carbon monoxide. Res. Commun. Chem. Pathol. Pharmacol. 81 (1993) 15-20
95. Miro O., Casademont J., Barrientos A., Urbano-Marquez A., and Cardellach F. Mitochondrial cytochrome c oxidase inhibition during acute carbon monoxide poisoning. Pharmacol. Toxicol. 82 (1998) 199-202
96. Molina J.A., Jimenez-Jimenez F.J., Orti-Pareja M., and Navarro J.A. The role of nitric oxide in neurodegeneration. Potential for pharmacological intervention. Drugs Aging 12 (1998) 251-259
97. Moore P.K., Bhatia M., and Moochhala S. Hydrogen sulphide: from the smell of the past to the mediator of the future?. Trends Pharmacol. Sci. 24 (2003) 609-611
98. Murphy M.P. How mitochondria produce reactive oxygen species. Biochem. J. 417 (2009) 1-13
99. Nicholls P., and Kim J.K. Sulphide as an inhibitor and electron donor for the cytochrome c oxidase system. Can. J. Biochem. 60 (1982) 613-623
100. Nicholson R.A., Roth S.H., Zhang A., Zheng J., Brookes J., Skrainy B., and Bennington R. Inhibition of respiratory and bioenergetic mechanisms by hydrogen sulphide in mammalian brain. J. Toxicol. Environ. Health A 54 (1998) 491-507
101. Nisoli E., Clementi E., Paolucci C., Cozzi V., Tonello C., Sciorati C., Bracale R., Valerio A., Francolini M., Moncada S., and Carruba M.O. Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science 299 (2003) 896-899
102. Oh G.S., Pae H.O., Lee B.S., Kim B.N., Kim J.M., Kim H.R., Jeon S.B., Jeon W.K., Chae H.J., and Chung H.T. Hydrogen sulphide inhibits nitric oxide production and nuclear factor-kappa B via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide. Free Radical Biol. Med. 41 (2006) 106-119
103. 2S. Acta Histochem. 111 (2009) 244-256
104. Palmer R.M., Ferrige A.G., and Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327 (1987) 524-526
105. Pankow D., and Ponsold W. Effect of carbon monoxide exposure on heart cytochrome c oxidase activity of rats. Biomed. Biochim. Acta 43 (1984) 1185-1189
106. Pearce L.L., Bominaar E.L., Hill B.C., and Peterson J. Reversal of cyanide inhibition of cytochrome c oxidase by the auxiliary substrate nitric oxide. J. Biol. Chem. 278 (2003) 52139-52145
107. Pearce L.L., Lopez M.E., Martinez-Bosch S., and Peterson J. Antagonism of nitric oxide toward the inhibition of cytochrome c oxidase by carbon monoxide and cyanide. Chem. Res. Toxicol. 21 (2008) 2073-2081
108. Peralta J.G., Llesuy S., Evelson P., Carreras M.C., Flecha B.G., and Poderoso J.J. Oxidative stress in skeletal muscle during sepsis in rats. Circ. Shock. 39 (1993) 153-159
109. Persichini T., Mazzone V., Polticelli F., Moreno S., Venturini G., Clementi E., and Colasanti M. Mitochondrial type I nitric oxide synthase physically interacts with cytochrome c oxidase. Neurosci. Lett. 384 (2005) 254-259
110. Petersen L.C. The effect of inhibitors on the oxygen kinetics of cytochrome c oxidase. Biochim. Biophys. Acta 460 (1977) 299-307
111. Piantadosi C.A. Biological chemistry of carbon monoxide. Antioxid. Redox Signal. 4 (2002) 259-270
112. Piantadosi C.A. Carbon monoxide, reactive oxygen signalling and oxidative stress. Free Radical Biol. Med. 45 (2008) 562-569
113. Piantadosi C.A., Lee P.A., and Sylvia A.L. Direct effects of CO on cerebral energy metabolism in bloodless rats. J. Appl. Physiol. 65 (1988) 878-887
114. Piantadosi C.A., Tatro L., and Zhang J. Hydroxyl radical production in the brain after CO hypoxia in rats. Free Radical Biol. Med. 18 (1995) 603-609
115. Piantadosi C.A., Zhang J., Levin E.D., Folz R.J., and Schmechel D.E. Apoptosis and delayed neuronal damage after carbon monoxide poisoning in the rat. Exp. Neurol. 147 (1997) 103-114
116. Piantadosi C.A., Carraway M.S., and Suliman H.B. Carbon monoxide, oxidative stress, and mitochondrial permeability pore transition. Free Radical Biol. Med. 40 (2006) 1332-1339
117. Piantadosi C.A., Carraway M.S., Babikr A., and Suliman H.B. Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1. Circ. Res. 103 (2008) 1232-1240
118. Ponderoso J.J., Carreras M.C., Lisdero C., Riobo N., Schopfer F., and Boveris A. Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondria and submitochondrial particles. Arch. Biochem. Biophys. 328 (1996) 85-92
119. Pong W.W., and Eldred W.D. Interactions of the gaseous neuromodulators nitric oxide, carbon monoxide, and hydrogen sulphide in the salamander retina. J. Neurosci. Res. (2009) 10.1002/jnr.22042
120. Prockop L.D., and Chichkova R.I. Carbon monoxide intoxication: an updated review. J. Neurol. Sci. 262 (2007) 122-130
121. Radi R., Rodriguez M., Castro L., and Telleri R. Inhibition of mitochondrial electron transport by peroxynitrite. Arch. Biochem. Biophys. 308 (1994) 89-95
122. Riobo N.A., Melani M., Sanjuan N., Fiszman M.L., Gravielle M.C., Carreras M.C., Cadenas E., and Poderoso J.J. The modulation of mitochondrial nitric-oxide synthase activity in rat brain development. J. Biol. Chem. 277 (2002) 42447-42455
123. Sarkela T.M., Berthiaume J., Elfering S., Gybina A.A., and Giulivi C. The modulation of oxygen radical production by nitric oxide in mitochondria. J. Biol. Chem. 276 (2001) 6945-6949
124. Sarti P., Giuffre A., Forte E., Mastronicola D., Barone M.C., and Brunori M. Nitric oxide and cytochrome c oxidase: mechanisms of inhibition and NO degradation. Biochem. Biophys. Res. Commun. 274 (2000) 183-187
125. Saviani E.E., Orsi C.H., Oliveira J.F., Pinto-Maglio C.A., and Salgado I. Participation of the mitochondrial permeability transition pore in nitric oxide-induced plant cell death. FEBS Lett. 510 (2002) 136-140
126. 2+ channels via redox modulation of key cysteine residues by mitochondrial reactive oxygen species J. Biol. Chem. 283 (2008) 24412-24419
127. Silva G., Cunha A., Gregoire I.P., Seldon M.P., and Soares M.P. The antiapoptotic effect of heme oxygenase-1 in endothelial cells involves the degradation of p38 alpha MAPK isoform. J. Immunol. 177 (2006) 1894-1903
128. Slebos D.J., Ryter S.W., van der Toorn M., Liu F., Guo F., Baty C.J., Karlsson J.M., Watkins S.C., Kim H.P., Wang X., Lee J.S., Postma D.S., Kauffman H.F., and Choi A.M. Mitochondrial localization and function of heme oxygenase-1 in cigarette smoke-induced cell death. Am. J. Respir. Cell Mol. Biol. 36 (2007) 409-417
129. Sokal J.A., Opacka J., Gorny R., and Kolakowski J. Effect of different conditions of acute exposure to carbon monoxide on the cerebral high-energy phosphates and ultrastructure of brain mitochondria in rats. Toxicol. Lett. 11 (1982) 213-219
130. Srisook K., Han S.S., Choi H.S., Li M.H., Ueda H., Kim C., and Cha Y.N. CO from enhanced HO activity or from CORM-2 inhibits both O2- and NO production and downregulates HO-1 expression in LPS-stimulated macrophages. Biochem. Pharmacol. 71 (2006) 307-318
131. Stadler J., Billiar T.R., Curran R.D., Stuehr D.J., Ochoa J.B., and Simmons R.L. Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes. Am. J. Physiol. 260 (1991) C910-C916
132. Stadler J., Curran R.D., Ochoa J.B., Harbrecht B.G., Hoffman R.A., Simmons R.L., and Billiar T.R. Effect of endogenous nitric oxide on mitochondrial respiration of rat hepatocytes in vitro and in vivo. Arch. Surg. 126 (1991) 186-191
133. Stipanuk M.H., and Beck P.W. Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat. Biochem. J. 206 (1982) 267-277
134. Suliman H.B., Carraway M.S., Tatro L.G., and Piantadosi C.A. A new activating role for CO in cardiac mitochondrial biogenesis. J. Cell Sci. 120 (2007) 299-308
135. Taoka S., and Banerjee R. Characterization of NO binding to human cystathionine beta synthase: possible implications of the effects of CO and NO binding to the human enzyme. J. Inorg. Biochem. 87 (2001) 245-251
136. Taskiran D., Nesil T., and Alkan K. Mitochondrial oxidative stress in female and male rat brain after ex vivo carbon monoxide treatment. Toxicology 26 (2007) 645-651
137. Theissen U., and Martin W. Sulfide:quinone oxidoreductase (SQR) from the lugworm Arenicola marina shows cyanide- and thioredoxin-dependent activity. FEBS J. 275 (2008) 1131-1139
138. Therond P. Oxidative stress and damages to biomolecules (lipids, proteins, DNA). Ann. Pharm. Fr. 64 (2006) 383-389
139. Thom S.R., Fisher D., Xu Y.A., Notarfrancesco K., and Ischiropoulos H. Adaptive responses and apoptosis in endothelial cells exposed to carbon monoxide. Proc. Natl. Acad. Sci. USA 97 (2000) 1305-1310
140. Tofighi R., Tillmark N., Dare E., Aberg A.M., Larsson J.E., and Ceccatelli S. Hypoxia-independent apoptosis in neural cells exposed to carbon monoxide in vitro. Brain Res. 1098 (2006) 1-8
141. Tsui T.Y., Siu Y.T., Scholitt H.J., and Fan S.T. Heme oxygenase-1-derived carbon monoxide stimulates adenosine triphosphate generation in human hepatocytes. Biochem. Biophys. Res. Commun. 336 (2005) 898-902
142. Tsukihara T., Aoyama H., Yamashita E., Tomizaki T., Yamaguchi H., Shinzawa I.K., Nakashima R., Yaono R., and Yoshikawa S. The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 angstrom. Science 272 (1996) 1136-1144
143. Uemura K., Harada K., Sadamitsu D., Tsuruta R., Takahashi M., Aki T., Yasuhara M., Maekawa T., and Yoshida K. Apoptotic and necrotic brain lesions in a fatal case of carbon monoxide poisoning. Forensic Sci. Int. 116 (2001) 213-219
144. Ushmorov A., Ratter F., Lehmann V., Droge W., Schirrmacher V., and Umansky V. Nitric oxide-induced apoptosis in human leukemic lines requires mitochondrial lipid degradation and cytochrome c release. Blood 93 (1999) 2342-2352
145. Valdez L.B., Zaobornyj T., Alvarez S., Bustamante J., Costa L.E., and Boveris A. Heart mitochondrial nitric oxide synthase. Effects of hypoxia and aging. Mol. Aspects Med. 25 (2004) 49-59
146. Varon J., Marik P.E., Fromm R.E.J., and Gueler A. Carbon monoxide poisoning: a review for clinicians. J. Emerg. Med. 17 (1999) 87-93
147. Vieira H.L., Queiroga C.S., and Alves P.M. Pre-conditioning induced by carbon monoxide provides neuronal protection against apoptosis. J. Neurochem. 107 (2008) 375-384
148. Vlasova I.I., Tyurin V.A., Kapralov A.A., Krunikov I.V., Osipov A.N., Potapovich M.V., Stovanovsky D.A., and Kagan V.E. Nitric oxide inhibits peroxidise activity of cytochrome c-cardiolipin complex and blocks cardiolipin oxidation. J. Biol. Chem. 281 (2006) 4554-4562
149. Volkel S., and Grieshaber M.K. Mitochondrial sulphide oxidation in Arenicola marina. Evidence for alternative electron pathways. Eur. J. Biochem. 235 (1996) 231-237
150. 2S be the third endogenous gaseous transmitter?. FASEB J. 16 (2002) 1792-1798
151. Wang C.Z., Li A., and Yang Z.C. The pathophysiology of carbon monoxide poisoning and acute respiratory failure in a sheep model with smoke inhalation injury. Chest 97 (1990) 736-742
152. Wang Y.F., Jin H.F., Tang C.S., and Du J.B. Role of gasotransmitters in the pathogenesis of pulmonary hypertension. Beijing Da Xue Xue Bao 38 (2006) 326-330
153. Warenycia M.W., Goodwin L.R., Benishin C.G., Reiffenstein R.J., Francom D.M., Taylor J.D., and Dieken F.P. Acute hydrogen sulphide poisoning. Demonstration of selective uptake of sulphide by the brainstem by measurement of brain sulphide levels. Biochem. Pharmacol. 38 (1989) 973-981
154. Wei T., Chen C., Hou J., Xin W., and Mori A. Nitric oxide induces oxidative stress and apoptosis in neuronal cells. Biochim. Biophys. Acta 1498 (2000) 72-79
155. Welter R., Yu L., and Yu C.A. The effects of nitric oxide on electron transport complexes. Arch. Biochem. Biophys. 331 (1996) 9-14
156. Wever R., van Gelder B.F., and Dervartanian D.V. Biochemical and biophysical studies on cytochrome c oxidase. XX. Reaction with sulphide. Biochim. Biophys. Acta 387 (1975) 189-193
157. Wu L., and Wang R. Carbon monoxide: endogenous production, physiological functions, and pharmacological applications. Pharmacol. Rev. 57 (2005) 585-630
158. Xu W., Charles I.G., and Moncada S. Nitric oxide: orchestrating hypoxia regulation through mitochondrial respiration and the endoplasmic reticulum stress response. Cell Res. 15 (2005) 63-65
159. Yoshida T., and Kikuchi G. Sequence of the reaction of heme catabolism catalysed by the microsomal heme oxygenase system. FEBS Lett. 48 (1974) 256-261
160. Yoshioka Y., Yamamuro A., and Maeda S. Nitric oxide/cGMP signalling pathway protects RAW264 cells against nitric oxide-induced apoptosis by inhibiting the activation of p38 mitogen-activated protein kinase. J. Pharmacol. Sci. 101 (2006) 126-134
161. Young L.J., and Caughey W.S. Oxygenation of carbon monoxide by bovine heart cytochrome c oxidase. Biochemistry 25 (1986) 152-161
162. Zemojtel T., Kolanczyk M., Kossler N., Stricker S., Lurz R., Mikula I., Duchniewicz M., Schuelke M., Ghafourifar P., Martasek P., Vingron M., and Mundlos S. Mammalian mitochondrial nitric oxide synthase: characterization of a novel candidate. FEBS Lett. 580 (2006) 455-462
163. Zhang X., Shan P., Alam J., Fu X.Y., and Lee P.J. Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase/Akt and p38 kinase-dependent STAT3 pathway during anoxia-reoxygenation injury. J. Biol. Chem. 280 (2005) 8714-8721
164. ATP channel opener. EMBO J. 20 (2001) 6008-6016
165. Zuckerbraun B.S., Chin B.Y., Bilban M., Costa d'Avila J., Rao J., Billiar T.R., and Ottebein L.E. Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species. FASEB J. 21 (2007) 1099-1106