CO from enhanced HO activity or from CORM-2 inhibits both O 2- and NO production and downregulates HO-1 expression in LPS-stimulated macrophages

Biochemical Pharmacology

Volumn 71, Issue 3, 2006, Pages 307-318

  Srisook, Klaokwan ^a,d   Han, Shan Shu ^a   Choi, Hyung Sim ^a   Li, Mei Hua ^b   Ueda, Hideo ^c   Kim, Chaekyun ^a   Cha, Young Nam ^a  

^a Inha University School of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Mitleben R and D Associates   (Japan)

^d BURAPHA UNIVERSITY   (Thailand)

Author keywords

Carbon monoxide; CORM 2; Heme oxygenase; Nitric oxide; Superoxide

Indexed keywords

BUTHIONINE SULFOXIMINE; CARBON MONOXIDE; CARBON MONOXIDE RELEASING MOLECULE 2; CYTOTOXIC AGENT; HEME; HEME OXYGENASE 1; HEMIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; OXIDOREDUCTASE; OXYGEN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTOPORPHYRIN ZINC; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL STIMULATION; CELL SURVIVAL; CYTOTOXICITY; DOSE RESPONSE; DOWN REGULATION; ENZYME MECHANISM; FENTON REACTION; MACROPHAGE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; UPREGULATION;

ANIMALS; CARBON MONOXIDE; CELL LINE; CELL SURVIVAL; DOWN-REGULATION; HEME OXYGENASE-1; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NEUTROPHILS; NITRIC OXIDE; ORGANOMETALLIC COMPOUNDS; SUPEROXIDES; TETRADECANOYLPHORBOL ACETATE;

EID: 29144519820     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.10.042     Document Type: Article

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