메뉴 건너뛰기




Volumn 12, Issue 4, 1998, Pages 251-259

The role of nitric oxide in neurodegeneration: Potential for pharmacological intervention

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR;

EID: 0031941816     PISSN: 1170229X     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002512-199812040-00001     Document Type: Article
Times cited : (68)

References (122)
  • 1
    • 0027062910 scopus 로고
    • The molecule of the year
    • Koshland Jr DE. The molecule of the year [editorial]. Science 1992; 258: 1861-3
    • (1992) Science , vol.258 , pp. 1861-1863
    • Koshland Jr., D.E.1
  • 2
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from L-arginine
    • Palmer RMJ, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988; 333: 664-6
    • (1988) Nature , vol.333 , pp. 664-666
    • Palmer, R.M.J.1    Ashton, D.S.2    Moncada, S.3
  • 3
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • Palmer RMJ, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987; 327: 524-6
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.J.1    Ferrige, A.G.2    Moncada, S.3
  • 4
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991; 43: 109-42
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 5
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 1993; 329: 2002-12
    • (1993) N Engl J Med , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 7
    • 0026760948 scopus 로고
    • A novel neuronal messenger molecule in brain: The free radical, nitric oxide
    • Dawson TM, Dawson VL, Snyder SH. A novel neuronal messenger molecule in brain: the free radical, nitric oxide. Ann Neurol 1992; 32: 297-311
    • (1992) Ann Neurol , vol.32 , pp. 297-311
    • Dawson, T.M.1    Dawson, V.L.2    Snyder, S.H.3
  • 8
    • 0027104253 scopus 로고
    • Biochemistry of nitric oxide and its redox-activated forms
    • Stamler JS, Singel DJ, Loscalzo J. Biochemistry of nitric oxide and its redox-activated forms. Science 1992; 258: 1898-902
    • (1992) Science , vol.258 , pp. 1898-1902
    • Stamler, J.S.1    Singel, D.J.2    Loscalzo, J.3
  • 10
    • 0027975453 scopus 로고
    • Nitric oxide: A physiologic messenger molecule
    • Bredt DS, Snyder SH. Nitric oxide: a physiologic messenger molecule. Annu Rev Biochem 1994; 63: 175-95
    • (1994) Annu Rev Biochem , vol.63 , pp. 175-195
    • Bredt, D.S.1    Snyder, S.H.2
  • 11
    • 0028092958 scopus 로고
    • Nitric oxide synthases: Roles, tolls, and controls
    • Nathan C, Xie Q. Nitric oxide synthases: roles, tolls, and controls. Cell 1994; 78: 915-8
    • (1994) Cell , vol.78 , pp. 915-918
    • Nathan, C.1    Xie, Q.2
  • 12
    • 0027942678 scopus 로고
    • Nitric oxide implication in the control of neurosecretion by chromaffin cells
    • Oset-Gasque MJ, Parramón M, Hortelano S, et al. Nitric oxide implication in the control of neurosecretion by chromaffin cells. J Neurochem 1994; 63: 1693-700
    • (1994) J Neurochem , vol.63 , pp. 1693-1700
    • Oset-Gasque, M.J.1    Parramón, M.2    Hortelano, S.3
  • 13
    • 0027194540 scopus 로고
    • A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
    • Lipton SA, Chol YB, Pan ZH, et al. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 1993; 364: 626-32
    • (1993) Nature , vol.364 , pp. 626-632
    • Lipton, S.A.1    Chol, Y.B.2    Pan, Z.H.3
  • 14
    • 0028132836 scopus 로고
    • Redox signaling: Nitrosylation and related target interactions of nitric oxide
    • Stamler JS. Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell 1994; 78: 931-6
    • (1994) Cell , vol.78 , pp. 931-936
    • Stamler, J.S.1
  • 15
    • 0027915347 scopus 로고
    • Janus face of nitric oxide
    • Snyder SH. Janus face of nitric oxide [letter]. Nature 1993; 364: 577
    • (1993) Nature , vol.364 , pp. 577
    • Snyder, S.H.1
  • 16
    • 0029153913 scopus 로고
    • Apoptosis and neurosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures
    • Bonfoco E, Kraine D, Ankarcrona M, et al. Apoptosis and neurosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci U S A 1995; 92: 7162-6
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 7162-7166
    • Bonfoco, E.1    Kraine, D.2    Ankarcrona, M.3
  • 17
    • 0006106476 scopus 로고
    • Peroxynitrite (ONOO ) reacts with superoxide dismutase to give reactive nitronium ion
    • Ischiropoulos H, Zhu L, Chen J, et al. Peroxynitrite (ONOO ) reacts with superoxide dismutase to give reactive nitronium ion [abstract]. Free Radic Biol Med 1990; 9 Suppl. 1: 131
    • (1990) Free Radic Biol Med , vol.9 , Issue.1 SUPPL. , pp. 131
    • Ischiropoulos, H.1    Zhu, L.2    Chen, J.3
  • 18
    • 0026485192 scopus 로고
    • Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide-dismutase
    • Ischiropoulos H, Zhu L, Chen J, et al. Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide-dismutase. Arch Biochem Biophys 1992; 298: 431-7
    • (1992) Arch Biochem Biophys , vol.298 , pp. 431-437
    • Ischiropoulos, H.1    Zhu, L.2    Chen, J.3
  • 19
    • 0027325255 scopus 로고
    • Nitric oxide synthase structure and mechanism
    • Marletta MA. Nitric oxide synthase structure and mechanism. J Biol Chem 1993; 268: 12231-4
    • (1993) J Biol Chem , vol.268 , pp. 12231-12234
    • Marletta, M.A.1
  • 21
    • 0029989846 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibitors: Future therapies for CNS disorders?
    • Resink A, Dawson VL, Dawson TM. Nitric oxide synthase inhibitors: future therapies for CNS disorders? CNS Drugs 1996; 6: 351-7
    • (1996) CNS Drugs , vol.6 , pp. 351-357
    • Resink, A.1    Dawson, V.L.2    Dawson, T.M.3
  • 22
    • 0025011298 scopus 로고
    • Localization of nitric oxide synthetase indicating a neural role for nitric oxide
    • Bredt DS, Hwang PM, Snyder SH. Localization of nitric oxide synthetase indicating a neural role for nitric oxide. Nature 1990; 347: 768-70
    • (1990) Nature , vol.347 , pp. 768-770
    • Bredt, D.S.1    Hwang, P.M.2    Snyder, S.H.3
  • 23
    • 0030938587 scopus 로고    scopus 로고
    • Neuronal (type I) nitric oxide synthase regulates nuclear factor kB activity and immunologic (type II) nitric oxide synthase expression
    • Togashi H, Sasaki M, Frohman E, et al. Neuronal (type I) nitric oxide synthase regulates nuclear factor kB activity and immunologic (type II) nitric oxide synthase expression. Proc Natl Acad Sci U S A 1997; 94: 2676-80
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 2676-2680
    • Togashi, H.1    Sasaki, M.2    Frohman, E.3
  • 24
    • 0028326424 scopus 로고
    • Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: Implications for synaptic plasticity
    • Dinnerman JL, Dawson TM, Schell MJ, et al. Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity. Proc Natl Acad Sci U S A 1994; 91: 4214-8
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 4214-4218
    • Dinnerman, J.L.1    Dawson, T.M.2    Schell, M.J.3
  • 25
    • 0025941639 scopus 로고
    • Nitric oxide synthase-protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH-diaphorase
    • Bredt DS, Glatt CE, Hwang PM, et al. Nitric oxide synthase-protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH-diaphorase. Neuron 1991; 7: 615-24
    • (1991) Neuron , vol.7 , pp. 615-624
    • Bredt, D.S.1    Glatt, C.E.2    Hwang, P.M.3
  • 26
  • 27
    • 0025823405 scopus 로고
    • Nitric oxide synthetase and neuronal NADPH-diaphorase are identical in brain and peripheral tissues
    • Dawson TM, Bredt DS, Fotuhi M, et al. Nitric oxide synthetase and neuronal NADPH-diaphorase are identical in brain and peripheral tissues. Proc Natl Acad Sci U S A 1991; 88: 7797-801
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 7797-7801
    • Dawson, T.M.1    Bredt, D.S.2    Fotuhi, M.3
  • 28
    • 0028917372 scopus 로고
    • Nitric oxide signaling in the central nervous system
    • Garthwaite J, Boulton CL. Nitric oxide signaling in the central nervous system. Annu Rev Physiol 1995; 57: 683-706
    • (1995) Annu Rev Physiol , vol.57 , pp. 683-706
    • Garthwaite, J.1    Boulton, C.L.2
  • 29
    • 0028922422 scopus 로고
    • Nitric oxide: Pathophysiological mechanisms
    • Gross SS, Wolin MS. Nitric oxide: pathophysiological mechanisms. Annu Rev Physiol 1995; 57: 737-69
    • (1995) Annu Rev Physiol , vol.57 , pp. 737-769
    • Gross, S.S.1    Wolin, M.S.2
  • 30
    • 0028258386 scopus 로고
    • Mechanism of cytokine-induced destruction of rat insulinoma cells: The role of nitric oxide
    • Suárez-Pinzón WL, Strynadka K, Schultz R, et al. Mechanism of cytokine-induced destruction of rat insulinoma cells: the role of nitric oxide. Endocrinology 1994; 134: 1006-10
    • (1994) Endocrinology , vol.134 , pp. 1006-1010
    • Suárez-Pinzón, W.L.1    Strynadka, K.2    Schultz, R.3
  • 31
    • 0026321495 scopus 로고
    • DNA deaminating ability and genotoxicity of nitric oxide and its progenitors
    • Wink DA, Kasprzak KS, Maragos CH, et al. DNA deaminating ability and genotoxicity of nitric oxide and its progenitors. Science 1991; 254: 1001-3
    • (1991) Science , vol.254 , pp. 1001-1003
    • Wink, D.A.1    Kasprzak, K.S.2    Maragos, C.H.3
  • 32
    • 0028294246 scopus 로고
    • Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity
    • Zhang J, Dawson VL, Dawson TM, et al. Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 1994; 263: 687-9
    • (1994) Science , vol.263 , pp. 687-689
    • Zhang, J.1    Dawson, V.L.2    Dawson, T.M.3
  • 33
    • 0026213769 scopus 로고
    • Poly(ADP-ribose) polymerase: Molecular biological aspects
    • de Murcia G, Menisser-de Murcia J, Schreiber V. Poly(ADP-ribose) polymerase: molecular biological aspects. Bioessays 1991; 13: 455-62
    • (1991) Bioessays , vol.13 , pp. 455-462
    • Murcia, G.1    Menisser-de Murcia, J.2    Schreiber, V.3
  • 34
    • 0025695636 scopus 로고
    • Nitric oxide mediates iron release from ferritin
    • Reif DW, Simmons RD. Nitric oxide mediates iron release from ferritin. Arch Biochem Biophys 1990; 283: 537-41
    • (1990) Arch Biochem Biophys , vol.283 , pp. 537-541
    • Reif, D.W.1    Simmons, R.D.2
  • 35
    • 0028026868 scopus 로고
    • Nitric oxide synthase: Aspects concerning structure and catalysis
    • Marletta MA. Nitric oxide synthase: aspects concerning structure and catalysis. Cell 1994; 78: 927-30
    • (1994) Cell , vol.78 , pp. 927-930
    • Marletta, M.A.1
  • 36
    • 28044464985 scopus 로고
    • Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide: Implications for neurodegenerative diseases
    • Cleeter MV, Cooper JM, Darley-Usmar VM, et al. Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide: implications for neurodegenerative diseases. FEBS Lett 1994; 345: 50-4
    • (1994) FEBS Lett , vol.345 , pp. 50-54
    • Cleeter, M.V.1    Cooper, J.M.2    Darley-Usmar, V.M.3
  • 37
    • 7144241679 scopus 로고
    • Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide
    • Kwon NS, Stuehr DJ, Nathan CF. Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide. Ann Neurol 1992; 32: 297-311
    • (1992) Ann Neurol , vol.32 , pp. 297-311
    • Kwon, N.S.1    Stuehr, D.J.2    Nathan, C.F.3
  • 38
    • 0026686667 scopus 로고
    • Nitric oxide stimulates auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase
    • Zhang J, Snyder SH. Nitric oxide stimulates auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase. Proc Natl Acad Sci U S A 1992; 89: 9382-5
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 9382-9385
    • Zhang, J.1    Snyder, S.H.2
  • 39
    • 0024296032 scopus 로고
    • Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain
    • Garthwaite J, Charles SL, Chess-Williams R. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature 1988; 336: 385-8
    • (1988) Nature , vol.336 , pp. 385-388
    • Garthwaite, J.1    Charles, S.L.2    Chess-Williams, R.3
  • 40
    • 0343046540 scopus 로고
    • Formation of nitric oxide from L-arginine in the central nervous system: A transduction mechanism for stimulation of soluble guanylate cyclase
    • Knowles RG, Palacios M, Palmer RMJ, et al. Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of soluble guanylate cyclase. Proc Natl Acad Sci U S A 1989; 86: 5159-62
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 5159-5162
    • Knowles, R.G.1    Palacios, M.2    Palmer, R.M.J.3
  • 41
    • 0026077959 scopus 로고
    • Glutamate, nitric oxide and cell-cell signaling in the nervous system
    • Garthwaite J. Glutamate, nitric oxide and cell-cell signaling in the nervous system. Trends Neurosci 1991; 14: 60-7
    • (1991) Trends Neurosci , vol.14 , pp. 60-67
    • Garthwaite, J.1
  • 42
    • 0024470719 scopus 로고
    • Kainate receptor linked to NO synthesis from arginine
    • Garthwaite J, Southam E, Anderton MA. Kainate receptor linked to NO synthesis from arginine. J Neurochem 1989; 53: 1952-4
    • (1989) J Neurochem , vol.53 , pp. 1952-1954
    • Garthwaite, J.1    Southam, E.2    Anderton, M.A.3
  • 43
    • 0027470952 scopus 로고
    • Non-classical glutamate receptor, blocked by both NMDA and non-NMDA antagonists, stimulate nitric oxide production in neurons
    • Marin P, Quignard JF, Lafon-Cazal M, et al. Non-classical glutamate receptor, blocked by both NMDA and non-NMDA antagonists, stimulate nitric oxide production in neurons. Neuropharmacology 1993; 32: 29-36
    • (1993) Neuropharmacology , vol.32 , pp. 29-36
    • Marin, P.1    Quignard, J.F.2    Lafon-Cazal, M.3
  • 44
    • 0027279689 scopus 로고
    • Role of intercellular and intracellular communication by nitric oxide in coupling of muscarinic receptors to activation of guanylate cyclase in neuronal cells
    • Hu J, El-Fakahany EE. Role of intercellular and intracellular communication by nitric oxide in coupling of muscarinic receptors to activation of guanylate cyclase in neuronal cells. J Neurochem 1993; 61: 578-85
    • (1993) J Neurochem , vol.61 , pp. 578-585
    • Hu, J.1    El-Fakahany, E.E.2
  • 45
    • 0027418574 scopus 로고
    • New signaling mechanism of angiotensin II in neuroblastoma neuro-2A cells: Activation of soluble guanylyl cyclase via nitric oxide synthesis
    • Chaki S, Inagami T. New signaling mechanism of angiotensin II in neuroblastoma neuro-2A cells: activation of soluble guanylyl cyclase via nitric oxide synthesis. Mol Pharmacol 1993; 43: 603-8
    • (1993) Mol Pharmacol , vol.43 , pp. 603-608
    • Chaki, S.1    Inagami, T.2
  • 46
    • 0026764488 scopus 로고
    • Angiotensin-induced cyclic GMP production is mediated by multiple receptor subtypes and nitric oxide in NIE-115 neuroblastoma cells
    • Zarhan ED, Ye X, Ades AM, et al. Angiotensin-induced cyclic GMP production is mediated by multiple receptor subtypes and nitric oxide in NIE-115 neuroblastoma cells. J Neurochem 1992; 58: 1960-3
    • (1992) J Neurochem , vol.58 , pp. 1960-1963
    • Zarhan, E.D.1    Ye, X.2    Ades, A.M.3
  • 47
    • 0025365431 scopus 로고
    • Mechanism of stimulation of cyclic-GMP level in a neuronal cell line mediated by serotonin (5-HT3) receptors
    • Reiser G. Mechanism of stimulation of cyclic-GMP level in a neuronal cell line mediated by serotonin (5-HT3) receptors. Eur J Biochem 1990; 189: 547-52
    • (1990) Eur J Biochem , vol.189 , pp. 547-552
    • Reiser, G.1
  • 48
    • 7144230420 scopus 로고
    • Hormone-induced biosynthesis of endothelium-derived relaxing factor/nitric oxide-like material in NIE-15 neuroblastoma cells requires calcium and calmodulin
    • Fostermann U, Gorsky LD, Pollock JS, et al. Hormone-induced biosynthesis of endothelium-derived relaxing factor/nitric oxide-like material in NIE-15 neuroblastoma cells requires calcium and calmodulin. Mol Pharmacol 1990; 101: 722-6
    • (1990) Mol Pharmacol , vol.101 , pp. 722-726
    • Fostermann, U.1    Gorsky, L.D.2    Pollock, J.S.3
  • 49
    • 7144220602 scopus 로고
    • ++ ionophore raise cyclic GMP levels in a neuronal cell line via formation of nitric oxide
    • ++ ionophore raise cyclic GMP levels in a neuronal cell line via formation of nitric oxide. Br J Pharmacol 1990; 38: 7-13
    • (1990) Br J Pharmacol , vol.38 , pp. 7-13
    • Reisert, G.1
  • 50
    • 0026078822 scopus 로고
    • Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum
    • Shibuki K, Okada D. Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum. Nature 1991; 349: 326-8
    • (1991) Nature , vol.349 , pp. 326-328
    • Shibuki, K.1    Okada, D.2
  • 51
    • 0025731428 scopus 로고
    • Possible involvement of nitric oxide in long-term potentiation
    • Bohme GA, Bon C, Stulzmann JM, et al. Possible involvement of nitric oxide in long-term potentiation. Eur J Pharmacol 1991; 199: 379-81
    • (1991) Eur J Pharmacol , vol.199 , pp. 379-381
    • Bohme, G.A.1    Bon, C.2    Stulzmann, J.M.3
  • 52
    • 0026325942 scopus 로고
    • Tests of the roles of two diffusible substances in long-term potentiation: Evidence for nitric oxide as a possible early retrograde messenger
    • O'Dell TJ, Hawkins RD, Kandel ER, et al. Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger. Proc Natl Acad Sci U S A 1991; 199: 11285-9
    • (1991) Proc Natl Acad Sci U S A , vol.199 , pp. 11285-11289
    • O'Dell, T.J.1    Hawkins, R.D.2    Kandel, E.R.3
  • 53
    • 0026326187 scopus 로고
    • A requirement for the intercellular messenger nitric-oxide in long-term potentiation
    • Schuman EE, Madison DW. A requirement for the intercellular messenger nitric-oxide in long-term potentiation. Science 1991; 254: 1503-6
    • (1991) Science , vol.254 , pp. 1503-1506
    • Schuman, E.E.1    Madison, D.W.2
  • 54
    • 0020647470 scopus 로고
    • Excitatory amino acids in synaptic transmission in the Shaffer collateral-commissural pathway of the rat hippocampus
    • Collingridge GL, Kehl SJ, McLennan H. Excitatory amino acids in synaptic transmission in the Shaffer collateral-commissural pathway of the rat hippocampus. J Physiol Lond 1983; 334: 33-46
    • (1983) J Physiol Lond , vol.334 , pp. 33-46
    • Collingridge, G.L.1    Kehl, S.J.2    McLennan, H.3
  • 55
    • 0026642215 scopus 로고
    • Inhibition of nitric oxide synthesis impairs two different forms of learning
    • Chapman PF, Atkins CM, Allen MT, et al. Inhibition of nitric oxide synthesis impairs two different forms of learning. Neuroreport 1992; 3: 567-70
    • (1992) Neuroreport , vol.3 , pp. 567-570
    • Chapman, P.F.1    Atkins, C.M.2    Allen, M.T.3
  • 57
    • 0025776498 scopus 로고
    • Evidence that nitric oxide modulates food intake in mice
    • Morley JE, Flood JF. Evidence that nitric oxide modulates food intake in mice. Life Sci 1991; 49: 707-11
    • (1991) Life Sci , vol.49 , pp. 707-711
    • Morley, J.E.1    Flood, J.F.2
  • 58
    • 0025922196 scopus 로고
    • L-N-nitro-arginine-methyl-ester exhibits antinociceptive activity in the mouse
    • Moore PK, Oluyomi AO, Babbedge RC, et al. L-N-nitro-arginine-methyl-ester exhibits antinociceptive activity in the mouse. Br J Pharmacol 1991; 102: 198-202
    • (1991) Br J Pharmacol , vol.102 , pp. 198-202
    • Moore, P.K.1    Oluyomi, A.O.2    Babbedge, R.C.3
  • 59
    • 0027329184 scopus 로고
    • Implications of NO/cGMP system in olfaction
    • Breer H, Shepherd GM. Implications of NO/cGMP system in olfaction. Trends Neurosci 1993; 16: 5-9
    • (1993) Trends Neurosci , vol.16 , pp. 5-9
    • Breer, H.1    Shepherd, G.M.2
  • 60
    • 0027195977 scopus 로고
    • Synthesis of nitric oxide in CNS glial cells
    • Murphy S, Simmons ML, Agullo L, et al. Synthesis of nitric oxide in CNS glial cells. Trends Neurosci 1993; 16: 323-8
    • (1993) Trends Neurosci , vol.16 , pp. 323-328
    • Murphy, S.1    Simmons, M.L.2    Agullo, L.3
  • 61
    • 0026483188 scopus 로고
    • Characterization of noradrenaline-stimulated cyclic GMP formation in brain astrocytes in culture
    • Agullo L, García A. Characterization of noradrenaline-stimulated cyclic GMP formation in brain astrocytes in culture. Biochem J 1992; 288: 619-24
    • (1992) Biochem J , vol.288 , pp. 619-624
    • Agullo, L.1    García, A.2
  • 62
    • 0026591114 scopus 로고
    • Different receptors mediate stimulation of nitric oxide-dependent cyclic GMP formation in neurons and astrocytes in culture
    • Agullo L, García A. Different receptors mediate stimulation of nitric oxide-dependent cyclic GMP formation in neurons and astrocytes in culture. Biochem Biophys Res Commun 1992; 182: 1362-8
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 1362-1368
    • Agullo, L.1    García, A.2
  • 63
    • 0025286140 scopus 로고
    • Evidence for an astrocyte-derived vasorelaxing factor with properties similar to nitric oxide
    • Murphy S, Minor RL, Welk G, et al. Evidence for an astrocyte-derived vasorelaxing factor with properties similar to nitric oxide. J Neurochem 1990; 55: 349-51
    • (1990) J Neurochem , vol.55 , pp. 349-351
    • Murphy, S.1    Minor, R.L.2    Welk, G.3
  • 64
    • 0025833116 scopus 로고
    • Central nervous system astroglial cells release nitrogen oxide(s) with vasorelaxant properties
    • Murphy S, Minor RL, Welk G, et al. Central nervous system astroglial cells release nitrogen oxide(s) with vasorelaxant properties. J Cardiovasc Pharmacol 1991; 7 Suppl 3: S265-8
    • (1991) J Cardiovasc Pharmacol , vol.7 , Issue.3 SUPPL.
    • Murphy, S.1    Minor, R.L.2    Welk, G.3
  • 65
    • 7144231483 scopus 로고
    • Cloning and expression of rat astroglial inducible nitric oxide synthase
    • Galea E, Reis DJ, Feinstein DL. Cloning and expression of rat astroglial inducible nitric oxide synthase [abstract]. Soc Neurosci Abst 1993; 19: 1121
    • (1993) Soc Neurosci Abst , vol.19 , pp. 1121
    • Galea, E.1    Reis, D.J.2    Feinstein, D.L.3
  • 66
    • 0026471158 scopus 로고
    • Activated astrocytes of the mouse hippocampus contain high levels of NADPH-diaphorase
    • Wallace MN, Fredens K. Activated astrocytes of the mouse hippocampus contain high levels of NADPH-diaphorase. Neuroreport 1992; 3: 953-6
    • (1992) Neuroreport , vol.3 , pp. 953-956
    • Wallace, M.N.1    Fredens, K.2
  • 67
    • 0027289707 scopus 로고
    • Reactive astrocytes express NADPH-diaphorase in vivo after transient ischemia
    • Endoch M, Maiese K, Pusinelli WA, et al. Reactive astrocytes express NADPH-diaphorase in vivo after transient ischemia. Neurosci Lett 1993; 154: 125-8
    • (1993) Neurosci Lett , vol.154 , pp. 125-128
    • Endoch, M.1    Maiese, K.2    Pusinelli, W.A.3
  • 68
    • 0344800998 scopus 로고
    • Transcription of the brain oxide nitric synthase gene in neural cell cultures
    • Mine-Golomb D, Schwartz JP. Transcription of the brain oxide nitric synthase gene in neural cell cultures [abstract]. Soc Neurosci Abst 1992; 18: 1004
    • (1992) Soc Neurosci Abst , vol.18 , pp. 1004
    • Mine-Golomb, D.1    Schwartz, J.P.2
  • 69
    • 0025803732 scopus 로고
    • Predominant localization in glial cells of free L-arginine: Immunocytochemical evidence
    • Aoki E, Sembra R, Mikosshiba K, et al. Predominant localization in glial cells of free L-arginine: immunocytochemical evidence. Brain Res 1991; 547: 190-2
    • (1991) Brain Res , vol.547 , pp. 190-192
    • Aoki, E.1    Sembra, R.2    Mikosshiba, K.3
  • 70
    • 0026522641 scopus 로고
    • Nitric oxide-induced blockade of NMDA receptors
    • Manzoni O, Prezeau L, Marin P, et al. Nitric oxide-induced blockade of NMDA receptors. Neurology 1992; 8: 653-62
    • (1992) Neurology , vol.8 , pp. 653-662
    • Manzoni, O.1    Prezeau, L.2    Marin, P.3
  • 71
    • 0027381424 scopus 로고
    • Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species
    • Wink DA, Hanbauer I, Krishna MC, et al. Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species. Proc Natl Acad Sci U S A 1992; 90: 9813-7
    • (1992) Proc Natl Acad Sci U S A , vol.90 , pp. 9813-9817
    • Wink, D.A.1    Hanbauer, I.2    Krishna, M.C.3
  • 72
    • 0029691756 scopus 로고    scopus 로고
    • Chemical biology of nitric oxide: Regulation and protective and toxic mechanism
    • Wink DA, Hanbauer I, Grisham MB, et al. Chemical biology of nitric oxide: regulation and protective and toxic mechanism. Curr Top Cell Regul 1996; 34: 159-87
    • (1996) Curr Top Cell Regul , vol.34 , pp. 159-187
    • Wink, D.A.1    Hanbauer, I.2    Grisham, M.B.3
  • 73
    • 0030988138 scopus 로고    scopus 로고
    • Nitric oxide synthase in models of local ischemia
    • Samdani AF, Dawson TM, Dawson VL. Nitric oxide synthase in models of local ischemia. Stroke 1997; 28: 1283-8
    • (1997) Stroke , vol.28 , pp. 1283-1288
    • Samdani, A.F.1    Dawson, T.M.2    Dawson, V.L.3
  • 74
    • 0026484388 scopus 로고
    • The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
    • Fahn S, Cohen G. The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann Neurol 1992; 32: 804-12
    • (1992) Ann Neurol , vol.32 , pp. 804-812
    • Fahn, S.1    Cohen, G.2
  • 75
    • 0027497409 scopus 로고
    • The possible role of iron in the etiopathology of Parkinson's disease
    • Youdim MBH, Ben-Sachar D, Riederer P. The possible role of iron in the etiopathology of Parkinson's disease. Mov Disord 1993; 8: 1-12
    • (1993) Mov Disord , vol.8 , pp. 1-12
    • Youdim, M.B.H.1    Ben-Sachar, D.2    Riederer, P.3
  • 76
    • 0027351360 scopus 로고
    • The neurotoxicity of iron and nitric oxide, relevance to the etiology of Parkinson's disease
    • Youdim MBH, Ben-Sachar D, Eshel G, et al. The neurotoxicity of iron and nitric oxide, relevance to the etiology of Parkinson's disease. Adv Neurol 1993; 60: 259-66
    • (1993) Adv Neurol , vol.60 , pp. 259-266
    • Youdim, M.B.H.1    Ben-Sachar, D.2    Eshel, G.3
  • 77
    • 0024378999 scopus 로고
    • Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum
    • Bret DS, Snyder SH. Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc Natl Acad Sci U S A 1989; 86: 5159-62
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 5159-5162
    • Bret, D.S.1    Snyder, S.H.2
  • 78
    • 0026567610 scopus 로고
    • Nitric oxide takes center stage with newly defined roles
    • McCall T, Vallance P. Nitric oxide takes center stage with newly defined roles. Trends Pharmacol Sci 1991; 13: 1-6
    • (1991) Trends Pharmacol Sci , vol.13 , pp. 1-6
    • McCall, T.1    Vallance, P.2
  • 79
    • 0025254401 scopus 로고
    • Mitochondrial complex I deficiency in Parkinson's disease
    • Schapira AH, Cooper JM, Dexter D, et al. Mitochondrial complex I deficiency in Parkinson's disease. J Neurochem 1990; 54: 523-7
    • (1990) J Neurochem , vol.54 , pp. 523-527
    • Schapira, A.H.1    Cooper, J.M.2    Dexter, D.3
  • 80
    • 0030010370 scopus 로고    scopus 로고
    • Ex vivo measurement of brain tissue nitrite and nitrate accurately reflects nitric oxide synthase in vivo
    • Slater M, Duffy C, Garthwhite J, et al. Ex vivo measurement of brain tissue nitrite and nitrate accurately reflects nitric oxide synthase in vivo. J Neurochem 1996; 66: 1683-90
    • (1996) J Neurochem , vol.66 , pp. 1683-1690
    • Slater, M.1    Duffy, C.2    Garthwhite, J.3
  • 81
    • 0029003713 scopus 로고
    • Nitrite, nitrate and cGMP in the cerebrospinal fluid in degenerative neurologic disease
    • Ikeda M, Sato I, Yuasa T, et al. Nitrite, nitrate and cGMP in the cerebrospinal fluid in degenerative neurologic disease. J Neural Transm Gen Sect 1995; 100: 263-7
    • (1995) J Neural Transm Gen Sect , vol.100 , pp. 263-267
    • Ikeda, M.1    Sato, I.2    Yuasa, T.3
  • 82
    • 0029982104 scopus 로고    scopus 로고
    • Cerebrospinal fluid nitrate levels in patients with Parkinson's disease
    • Molina JA, Jiménez-Jiménez FJ, Navarro JA, et al. Cerebrospinal fluid nitrate levels in patients with Parkinson's disease. Acta Neurol Scand 1996; 93: 123-6
    • (1996) Acta Neurol Scand , vol.93 , pp. 123-126
    • Molina, J.A.1    Jiménez-Jiménez, F.J.2    Navarro, J.A.3
  • 83
    • 0028153979 scopus 로고
    • Decreased cerebrospinal fluid nitrate levels in Parkinson's disease. Alzheimer's disease and multiple system atrophy patients
    • Kuiper MA, Visser JJ, Bergsman PL, et al. Decreased cerebrospinal fluid nitrate levels in Parkinson's disease. Alzheimer's disease and multiple system atrophy patients. J Neurol Sci 1994; 121: 46-9
    • (1994) J Neurol Sci , vol.121 , pp. 46-49
    • Kuiper, M.A.1    Visser, J.J.2    Bergsman, P.L.3
  • 84
    • 0029121786 scopus 로고
    • Increased cerebrospinal fluid concentration of nitrite in Parkinson's disease
    • Qureshi GA, Baigh S, Bednar I, et al. Increased cerebrospinal fluid concentration of nitrite in Parkinson's disease. Neuroreport 1995; 6: 1642-4
    • (1995) Neuroreport , vol.6 , pp. 1642-1644
    • Qureshi, G.A.1    Baigh, S.2    Bednar, I.3
  • 85
    • 0028174378 scopus 로고
    • NADPH-diaphorase/nitric oxide containing neurons in normal and Parkinson's disease putamen
    • Bockelmann R, Wolf G, Ransmayr G, et al. NADPH-diaphorase/nitric oxide containing neurons in normal and Parkinson's disease putamen. J Neural Transm Park Dis Dement Sect 1994; 7: 115-21
    • (1994) J Neural Transm Park Dis Dement Sect , vol.7 , pp. 115-121
    • Bockelmann, R.1    Wolf, G.2    Ransmayr, G.3
  • 86
    • 0343844458 scopus 로고    scopus 로고
    • Nitric oxide synthase and neuronal vulnerability in Parkinson's disease
    • Hunot S, Boissiere F, Faucheux B, et al. Nitric oxide synthase and neuronal vulnerability in Parkinson's disease. Neuroscience 1996; 72: 355-63
    • (1996) Neuroscience , vol.72 , pp. 355-363
    • Hunot, S.1    Boissiere, F.2    Faucheux, B.3
  • 87
    • 0029933143 scopus 로고    scopus 로고
    • Neutrophil function, nitric oxide, and blood oxidative stress in Parkinson's disease
    • Gatto EM, Carreras MC, Pargament GA, et al. Neutrophil function, nitric oxide, and blood oxidative stress in Parkinson's disease. Mov Disord 1996; 11: 261-7
    • (1996) Mov Disord , vol.11 , pp. 261-267
    • Gatto, E.M.1    Carreras, M.C.2    Pargament, G.A.3
  • 88
    • 0028796770 scopus 로고
    • Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice
    • Schulz JB, Matthews RT, Muqit MM, et al. Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice. J Neurochem 1995; 64: 936-9
    • (1995) J Neurochem , vol.64 , pp. 936-939
    • Schulz, J.B.1    Matthews, R.T.2    Muqit, M.M.3
  • 89
    • 0029984860 scopus 로고    scopus 로고
    • Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced dopaminergic neurotoxicity
    • Przedborski S, Jackson-Lewis V, Yokohama K, et al. Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced dopaminergic neurotoxicity. Proc Natl Acad Sci U S A 1996; 93: 4565-71
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 4565-4571
    • Przedborski, S.1    Jackson-Lewis, V.2    Yokohama, K.3
  • 90
    • 0029844003 scopus 로고    scopus 로고
    • Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons
    • Hantraye P, Brouillet E, Ferrante R, et al. Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons. Nature Med 1996; 2: 1017-21
    • (1996) Nature Med , vol.2 , pp. 1017-1021
    • Hantraye, P.1    Brouillet, E.2    Ferrante, R.3
  • 91
    • 0028559817 scopus 로고
    • Reduction of MPP(+)-induced hydroxyl radical formation and nigrostriatal MPTP toxicity by inhibiting nitric oxide synthase
    • Smith TS, Swerdlow RH, Parker Jr WD, et al. Reduction of MPP(+)-induced hydroxyl radical formation and nigrostriatal MPTP toxicity by inhibiting nitric oxide synthase. Neuroreport 1994; 5: 2598-600
    • (1994) Neuroreport , vol.5 , pp. 2598-2600
    • Smith, T.S.1    Swerdlow, R.H.2    Parker Jr., W.D.3
  • 92
    • 0029805318 scopus 로고    scopus 로고
    • Role of nitric oxide in methamphetamine neurotoxicity: Protection by 7-nitroindazole, an inhibitor of neuronal nitric oxide synthase
    • Di Monte DA, Royland JE, Jakowec MW, et al. Role of nitric oxide in methamphetamine neurotoxicity: protection by 7-nitroindazole, an inhibitor of neuronal nitric oxide synthase. J Neurochem 1996; 67: 2443-50
    • (1996) J Neurochem , vol.67 , pp. 2443-2450
    • Di Monte, D.A.1    Royland, J.E.2    Jakowec, M.W.3
  • 93
    • 0026718966 scopus 로고
    • Brain cytochromic oxidase in Alzheimer's disease
    • Kish SJ, Bergeron C, Rajput A, et al. Brain cytochromic oxidase in Alzheimer's disease. J Neurochem 1992; 59: 776-9
    • (1992) J Neurochem , vol.59 , pp. 776-779
    • Kish, S.J.1    Bergeron, C.2    Rajput, A.3
  • 94
    • 0028236018 scopus 로고
    • Electron transport chain defects in Alzheimer's disease brain
    • Parker WD, Parks JK, Filley CM, et al. Electron transport chain defects in Alzheimer's disease brain. Neurology 1994; 44: 1090-6
    • (1994) Neurology , vol.44 , pp. 1090-1096
    • Parker, W.D.1    Parks, J.K.2    Filley, C.M.3
  • 95
    • 0028110234 scopus 로고
    • Cortical cytochrome oxidase activity is reduced in Alzheimer's disease
    • Mutisya EM, Bowling AC, Beal ME. Cortical cytochrome oxidase activity is reduced in Alzheimer's disease. J Neurochem 1994; 63: 2179-84
    • (1994) J Neurochem , vol.63 , pp. 2179-2184
    • Mutisya, E.M.1    Bowling, A.C.2    Beal, M.E.3
  • 96
    • 0030583248 scopus 로고    scopus 로고
    • Synergistic induction of nitric oxide by beta-amyloid and cytokines in astrocytes
    • Rossi F, Bianchini E. Synergistic induction of nitric oxide by beta-amyloid and cytokines in astrocytes. Biochem Biophys Res Commun 1996; 225: 474-8
    • (1996) Biochem Biophys Res Commun , vol.225 , pp. 474-478
    • Rossi, F.1    Bianchini, E.2
  • 97
    • 0028953529 scopus 로고
    • Activation of microglial cells by beta-amyloid protein and interferon-gamma
    • Meda L, Cassatella MA, Szendri GI, et al. Activation of microglial cells by beta-amyloid protein and interferon-gamma. Nature 1995; 374: 647-50
    • (1995) Nature , vol.374 , pp. 647-650
    • Meda, L.1    Cassatella, M.A.2    Szendri, G.I.3
  • 98
    • 10244235267 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease
    • Vodovotz Y, Lucia MS, Flanders KC, et al. Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease. J Exp Med 1996; 184: 1425-33
    • (1996) J Exp Med , vol.184 , pp. 1425-1433
    • Vodovotz, Y.1    Lucia, M.S.2    Flanders, K.C.3
  • 99
    • 0029902166 scopus 로고    scopus 로고
    • Evidence of neuronal oxidative damage in Alzheimer's disease
    • Good PF, Werner P, Hsu A, et al. Evidence of neuronal oxidative damage in Alzheimer's disease. Am J Pathol 1996; 149: 21-8
    • (1996) Am J Pathol , vol.149 , pp. 21-28
    • Good, P.F.1    Werner, P.2    Hsu, A.3
  • 100
    • 0028123121 scopus 로고
    • Cerebrospinal fluid nitrite/nitrate levels in neurologic diseases
    • Milstien S, Sakai N, Brew BJ, et al. Cerebrospinal fluid nitrite/nitrate levels in neurologic diseases. J Neurochem 1994; 63: 1178-80
    • (1994) J Neurochem , vol.63 , pp. 1178-1180
    • Milstien, S.1    Sakai, N.2    Brew, B.J.3
  • 101
    • 8044229436 scopus 로고    scopus 로고
    • Cerebrospinal fluid nitrate levels in patients with Alzheimer's disease
    • Navarro JA, Molina JA, Jiménez-Jiménez FJ, et al. Cerebrospinal fluid nitrate levels in patients with Alzheimer's disease. Acta Neurol Scand 1996; 94: 411-4
    • (1996) Acta Neurol Scand , vol.94 , pp. 411-414
    • Navarro, J.A.1    Molina, J.A.2    Jiménez-Jiménez, F.J.3
  • 102
    • 0027298974 scopus 로고
    • The pattern of NADPH-diaphorase staining, a marker of nitric oxide synthase activity, is altered in the perforant pathway terminal zone in Alzheimer's disease
    • Rebeck GW, Marzloff K, Hyman BT. The pattern of NADPH-diaphorase staining, a marker of nitric oxide synthase activity, is altered in the perforant pathway terminal zone in Alzheimer's disease. Neurosci Lett 1993; 152: 165-8
    • (1993) Neurosci Lett , vol.152 , pp. 165-168
    • Rebeck, G.W.1    Marzloff, K.2    Hyman, B.T.3
  • 103
    • 0040510653 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase (nNOS) mRNA expression and NADPH-diaphorase staining in the frontal cortex, visual cortex and hippocampus of control and Alzheimer's disease brains
    • Norris PJ, Faull RL, Emson PC. Neuronal nitric oxide synthase (nNOS) mRNA expression and NADPH-diaphorase staining in the frontal cortex, visual cortex and hippocampus of control and Alzheimer's disease brains. Brain Res Mol Brain Res 1996; 41: 36-49
    • (1996) Brain Res Mol Brain Res , vol.41 , pp. 36-49
    • Norris, P.J.1    Faull, R.L.2    Emson, P.C.3
  • 104
    • 0026480838 scopus 로고
    • Relative sparing of nitric oxide synthase-containing neurons in the hippocampal formation in Alzheimer's disease
    • Hyman BT, Marzloff K, Wenniger JJ, et al. Relative sparing of nitric oxide synthase-containing neurons in the hippocampal formation in Alzheimer's disease. Ann Neurol 1992; 32: 818-20
    • (1992) Ann Neurol , vol.32 , pp. 818-820
    • Hyman, B.T.1    Marzloff, K.2    Wenniger, J.J.3
  • 105
    • 0028883271 scopus 로고
    • Reduced nitric oxide responsive soluble guanylyl cyclase activity in the superior temporal cortex of patients with Alzheimer's disease
    • Bonkale WL, Winblad B, Ravid R, et al. Reduced nitric oxide responsive soluble guanylyl cyclase activity in the superior temporal cortex of patients with Alzheimer's disease. Neurosci Lett 1995; 187: 5-8
    • (1995) Neurosci Lett , vol.187 , pp. 5-8
    • Bonkale, W.L.1    Winblad, B.2    Ravid, R.3
  • 106
    • 0028124916 scopus 로고
    • Nitric oxide synthase activity is elevated in brain microvessels in Alzheimer's disease
    • Dorheim MA, Tracey WR, Pollock JS, et al. Nitric oxide synthase activity is elevated in brain microvessels in Alzheimer's disease. Biochem Biophys Res Commun 1994; 205: 659-65
    • (1994) Biochem Biophys Res Commun , vol.205 , pp. 659-665
    • Dorheim, M.A.1    Tracey, W.R.2    Pollock, J.S.3
  • 107
    • 0027988579 scopus 로고
    • Inhibitors of free radical formation fail to attenuate direct beta-amyloid 25-35 peptide-mediated neurotoxicity in rat hippocampal cultures
    • Lockhart BP, Benicourt C, Junien JL, et al. Inhibitors of free radical formation fail to attenuate direct beta-amyloid 25-35 peptide-mediated neurotoxicity in rat hippocampal cultures. J Neurosci Res 1994; 39: 494-505
    • (1994) J Neurosci Res , vol.39 , pp. 494-505
    • Lockhart, B.P.1    Benicourt, C.2    Junien, J.L.3
  • 108
    • 0029991827 scopus 로고    scopus 로고
    • Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: An immunohistochemical study
    • Chou SM, Wang HS, Komai K. Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: an immunohistochemical study. J Chem Neuroanal 1996; 10: 249-58
    • (1996) J Chem Neuroanal , vol.10 , pp. 249-258
    • Chou, S.M.1    Wang, H.S.2    Komai, K.3
  • 109
    • 0029840369 scopus 로고    scopus 로고
    • Role of SOD-1 and nitric oxide/cyclic GMP cascade on neurofilament aggregation in ALS/MND
    • Chou SM, Wang HS, Taniguchi A. Role of SOD-1 and nitric oxide/cyclic GMP cascade on neurofilament aggregation in ALS/MND. J Neurol Sci 1996; 134 Suppl.: 16-26
    • (1996) J Neurol Sci , vol.134 , Issue.SUPPL. , pp. 16-26
    • Chou, S.M.1    Wang, H.S.2    Taniguchi, A.3
  • 110
    • 0030040859 scopus 로고    scopus 로고
    • Alterations in nitrogen monoxide-synthesizing cortical neurons in amyotrophic lateral sclerosis with dementia
    • Kuljis RO, Schelper RL. Alterations in nitrogen monoxide-synthesizing cortical neurons in amyotrophic lateral sclerosis with dementia. J Neuropathol Exp Neurol 1996; 55: 25-35
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 25-35
    • Kuljis, R.O.1    Schelper, R.L.2
  • 111
    • 0029966584 scopus 로고    scopus 로고
    • Decreased neuronal nitric oxide synthase messenger RNA and somatostatin messenger RNA in the striatum on Huntington disease
    • Norris PJ, Waldvogel JH, Faull RL, et al. Decreased neuronal nitric oxide synthase messenger RNA and somatostatin messenger RNA in the striatum on Huntington disease. Neuroscience 1996; 72: 1037-47
    • (1996) Neuroscience , vol.72 , pp. 1037-1047
    • Norris, P.J.1    Waldvogel, J.H.2    Faull, R.L.3
  • 112
    • 0029899868 scopus 로고    scopus 로고
    • Huntington-associated protein (HAPI): Discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase
    • Li XJ, Sharp AH, Li SH, et al. Huntington-associated protein (HAPI): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase. Proc Natl Acad Sci U S A 1996; 93: 4839-44
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 4839-4844
    • Li, X.J.1    Sharp, A.H.2    Li, S.H.3
  • 113
    • 0022343684 scopus 로고
    • Selective sparing of a class of striatal neurons in Huntington's disease
    • Ferrante RJ, Kowall NW, Beal MF, et al. Selective sparing of a class of striatal neurons in Huntington's disease. Science 1985; 30: 561-3
    • (1985) Science , vol.30 , pp. 561-563
    • Ferrante, R.J.1    Kowall, N.W.2    Beal, M.F.3
  • 114
    • 0026503434 scopus 로고
    • Calcineurin phosphatase activity in T lymphocytes is inhibited by FK506 and cyclosporin A
    • Fruman DA, Klee CB, Bierer BE, et al. Calcineurin phosphatase activity in T lymphocytes is inhibited by FK506 and cyclosporin A. Proc Natl Acad Sci U S A. 1992; 89: 3686-90
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 3686-3690
    • Fruman, D.A.1    Klee, C.B.2    Bierer, B.E.3
  • 115
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FK 506 complexes
    • Liu J, Farmer JD, Lane WS, et al. Calcineurin is a common target of cyclophilin-cyclosporin A and FK 506 complexes. Cell 1991; 66: 807-15
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer, J.D.2    Lane, W.S.3
  • 116
    • 0030067585 scopus 로고    scopus 로고
    • Corticosteroids inhibit expression of inducible nitric oxide synthase during acute cardiac allograft rejection
    • Worrall NK, Misko TP, Sullivan PM, et al. Corticosteroids inhibit expression of inducible nitric oxide synthase during acute cardiac allograft rejection. Transplantation 1996; 61: 324-8
    • (1996) Transplantation , vol.61 , pp. 324-328
    • Worrall, N.K.1    Misko, T.P.2    Sullivan, P.M.3
  • 117
    • 0031081781 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors
    • Minghetti L, Nicolini A, Polazzi E, et al. Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors. Glia 1997; 19: 152-60
    • (1997) Glia , vol.19 , pp. 152-160
    • Minghetti, L.1    Nicolini, A.2    Polazzi, E.3
  • 118
    • 0029786866 scopus 로고    scopus 로고
    • Inhibition by antioxidants of nitric oxide synthase expression in murine macrophages: Role of nuclear factor kappa B and interferon regulatory factor I
    • Hecker M, Preiss C, Klemm P, et al. Inhibition by antioxidants of nitric oxide synthase expression in murine macrophages: role of nuclear factor kappa B and interferon regulatory factor I. Br J Pharmacol 1996; 118: 2178-84
    • (1996) Br J Pharmacol , vol.118 , pp. 2178-2184
    • Hecker, M.1    Preiss, C.2    Klemm, P.3
  • 119
    • 0026994449 scopus 로고
    • Characterization of 2,4,5-trihydroxyphenylalanine neurotoxicity in vitro and protective effects of ganglioside GMI: Implications for Parkinson's disease
    • Skaper SD, Facci L, Schiavo N, et al. Characterization of 2,4,5-trihydroxyphenylalanine neurotoxicity in vitro and protective effects of ganglioside GMI: implications for Parkinson's disease. J Pharmacol Exp Ther 1992; 263: 1440-6
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 1440-1446
    • Skaper, S.D.1    Facci, L.2    Schiavo, N.3
  • 120
    • 0023932543 scopus 로고
    • GMI ganglioside protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced degeneration of nigrostriatal dopamine neurons in the black mouse
    • Janson AM, Agnati LF, Fuxe K, et al. GMI ganglioside protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced degeneration of nigrostriatal dopamine neurons in the black mouse. Acta Physiol Scand 1988; 132: 587-8
    • (1988) Acta Physiol Scand , vol.132 , pp. 587-588
    • Janson, A.M.1    Agnati, L.F.2    Fuxe, K.3
  • 122
    • 0028928579 scopus 로고
    • Neuroprotective effects of gangliosides may involve inhibition of nitric oxide synthase
    • Dawson TM, Hung K, Dawson VL, et al. Neuroprotective effects of gangliosides may involve inhibition of nitric oxide synthase. Ann Neurol 1995; 37: 115-8
    • (1995) Ann Neurol , vol.37 , pp. 115-118
    • Dawson, T.M.1    Hung, K.2    Dawson, V.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.