Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei

Nature Cell Biology

Volumn 12, Issue 2, 2010, Pages 185-192

  Oliveira, Raquel A ^a   Hamilton, Russell S ^a   Pauli, Andrea ^a,b   Davis, Ilan ^a   Nasmyth, Kim ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE PROMOTING COMPLEX; COHESIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 1; CYCLINE;

ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CENTROMERE; CHROMOSOME BREAKAGE; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DAUGHTER CELL; DROSOPHILA MELANOGASTER; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; METAPHASE; METAPHASE CHROMOSOME; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SISTER CHROMATID;

ANIMALS; CDC2 PROTEIN KINASE; CELL CYCLE PROTEINS; CELL NUCLEUS; CHROMOSOMAL PROTEINS, NON-HISTONE; CHROMOSOME SEGREGATION; CYCLIN-DEPENDENT KINASES; DROSOPHILA; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; KINETOCHORES; METAPHASE; MICROSCOPY; MICROTUBULES; UBIQUITIN-PROTEIN LIGASE COMPLEXES;

DROSOPHILA MELANOGASTER;

EID: 75949117626     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb2018     Document Type: Article

References (41)

1. Peters, J. M. The anaphase promoting complex/cyclosome: a machine designed to destroy. Nature Rev. Mol. Cell Biol. 7, 644-656 (2006).
2. Nasmyth, K. & Haering, C. H. The structure and function of SMC and kleisin complexes. Annu. Rev. Biochem. 74, 595-648 (2005).
3. Haering, C. H., Farcas, A. M., Arumugam, P., Metson, J. & Nasmyth, K. The cohesin ring concatenates sister DNA molecules. Nature 454, 297-301 (2008).
4. Yanagida, M. Clearing the way for mitosis: is cohesin a target? Nature Rev. Mol. Cell Biol. 10, 489-496 (2009).
5. Diaz-Martinez, L. A., Gimenez-Abian, J. F. & Clarke, D. J. Chromosome cohesion-rings, knots, orcs and fellowship. J. Cell Sci. 121, 2107-2114 (2008).
6. Guacci, V. Sister chromatid cohesion: the cohesin cleavage model does not ring true. Genes Cells 12, 693-708 (2007).
7. Pauli, A. et al. Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons. Dev. Cell 14, 239-251 (2008).
8. Coelho, P. A. et al. Dual role of topoisomerase II in centromere resolution and aurora B activity. PLoS Biol. 6, e207 (2008).
9. Toyoda, Y. & Yanagida, M. Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance. Mol. Biol. Cell 17, 2287-2302 (2006).
10. Uemura, T. et al. DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe. Cell 50, 917-925 (1987).
11. Porter, A. C. & Farr, C. J. Topoisomerase II: untangling its contribution at the centromere. Chromosome Res. 12, 569-583 (2004).
12. Shimada, K. & Gasser, S. M. The origin recognition complex functions in sister-chromatid cohesion in Saccharomyces cerevisiae. Cell 128, 85-99 (2007).
13. Lam, W. W., Peterson, E. A., Yeung, M. & Lavoie, B. D. Condensin is required for chromosome arm cohesion during mitosis. Genes Dev. 20, 2973-2984 (2006).
14. Uhlmann, F., Wernic, D., Poupart, M. A., Koonin, E. V. & Nasmyth, K. Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast. Cell 103, 375-386 (2000).
15. Sullivan, M., Higuchi, T., Katis, V. L. & Uhlmann, F. Cdc14 phosphatase induces rDNA condensation and resolves cohesin-independent cohesion during budding yeast anaphase. Cell 117, 471-482 (2004).
16. Losada, A., Hirano, M. & Hirano, T. Identification of Xenopus SMC protein complexes required for sister chromatid cohesion. Genes Dev. 12, 1986-1997 (1998).
17. Sonoda, E. et al. Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells. Dev. Cell 1, 759-770 (2001).
18. Vass, S. et al. Depletion of Drad21/Scc1 in Drosophila cells leads to instability of the cohesin complex and disruption of mitotic progression. Curr. Biol. 13, 208-218 (2003).
19. Sumara, I., Vorlaufer, E., Gieffers, C., Peters, B. H. & Peters, J. M. Characterization of vertebrate cohesin complexes and their regulation in prophase. J. Cell Biol. 151, 749-762 (2000).
20. Warren, W. D. et al. The Drosophila RAD21 cohesin persists at the centromere region in mitosis. Curr. Biol. 10, 1463-1466 (2000).
21. Musacchio, A. & Salmon, E. D. The spindle-assembly checkpoint in space and time. Nature Rev. Mol. Cell Biol. 8, 379-393 (2007).
22. Mapelli, M., Massimiliano, L., Santaguida, S. & Musacchio, A. The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint. Cell 131, 730-743 (2007).
23. Luo, X. et al. Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. Nature Struct. Biol. 7, 224-229 (2000).
24. Townsley, F. M., Aristarkhov, A., Beck, S., Hershko, A. & Ruderman, J. V. Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase. Proc. Natl Acad. Sci. USA 94, 2362-2367 (1997).
25. Logarinho, E. et al. Different spindle checkpoint proteins monitor microtubule attachment and tension at kinetochores in Drosophila cells. J. Cell Sci. 117, 1757-1771 (2004).
26. Buffin, E., Lefebvre, C., Huang, J., Gagou, M. E. & Karess, R. E. Recruitment of Mad2 to the kinetochore requires the Rod/Zw10 complex. Curr. Biol. 15, 856-861 (2005).
27. Schuh, M., Lehner, C. F. & Heidmann, S. Incorporation of Drosophila CID/CENP-A and CENP-C into centromeres during early embryonic anaphase. Curr. Biol. 17, 237-243 (2007).
28. Buchenau, P., Saumweber, H. & Arndt-Jovin, D. J. Consequences of topoisomerase II inhibition in early embryogenesis of Drosophila revealed by in vivo confocal laser scanning microscopy. J. Cell Sci. 104, 1175-1185 (1993).
29. Kelly, A. E. & Funabiki, H. Correcting aberrant kinetochore microtubule attachments: an Aurora B-centric view. Curr. Opin. Cell Biol. 21, 51-58 (2009).
30. Murata-Hori, M., Tatsuka, M. & Wang, Y. L. Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis. Mol. Biol. Cell 13, 1099-1108 (2002).
31. Murray, A. W., Solomon, M. J. & Kirschner, M. W. The role of cyclin synthesis and degradation in the control of maturation promoting factor activity. Nature 339, 280-286 (1989).
32. Shirayama, M., Toth, A., Galova, M. & Nasmyth, K. APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5. Nature 402, 203-207 (1999).
33. Thornton, B. R. & Toczyski, D. P. Securin and B-cyclin/CDK are the only essential targets of the APC. Nature Cell Biol. 5, 1090-1094 (2003).
34. Toyoshima, H. & Hunter, T. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78, 67-74 (1994).
35. Polyak, K. et al. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev. 8, 9-22 (1994).
36. Sullivan, M., Lehane, C. & Uhlmann, F. Orchestrating anaphase and mitotic exit: separase cleavage and localization of Slk19. Nature Cell Biol. 3, 771-777 (2001).
37. Tsou, M. F. et al. Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells. Dev. Cell 17, 344-354 (2009).
38. Sullivan, W., Ashburner, A. & Hawley, R. S. Drosophila Protocols (Cold Spring Harbor Laboratory Press, 2000).
39. Rape, M., Reddy, S. K. & Kirschner, M. W. The processivity of multiubiquitination by the APC determines the order of substrate degradation. Cell 124, 89-103 (2006).
40. McGuinness, B. E. et al. Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint. Curr. Biol. 19, 369-380 (2009).
41. Thevenaz, P., Ruttimann, U. E. & Unser, M. A pyramid approach to subpixel registration based on intensity. IEEE Trans. Image Process. 7, 27-41 (1998).