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Volumn 50, Issue 4, 2003, Pages 239-245

Antiproliferative and cancer chemopreventive activity of phytoalexins: Focus on indole phytoalexins from crucifers

Author keywords

Brassinin; Camalexin; Carcinogenesis; Chemoprevention; Phytoalexins; Spirobrassinin

Indexed keywords

1 METHOXYBRASSENIN; 1 METHOXYBRASSENIN B; 1 METHOXYBRASSININ A; 1 METHOXYBRASSITIN; 1 METHOXYSPIROBRASSININ; 1 METHOXYSPIROBRASSINOL; 4 METHOXYBRASSININ; 6 METHOXYCAMALEXIN; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; BRASSICANAL A; BRASSICANAL B; BRASSICANAL C; BRASSILEXIN; BRASSININ; BRASSITIN; CAMALEXIN; CYCLOBRASSININ; CYCLOBRASSININ SULFOXIDE; CYCLOBRASSINONE; DEHYDRO 4 METHOXYCYCLOBRASSININ; DIOXIBRASSININ; INDOLE DERIVATIVE; METHOXYSPIROBRASSINOL METHYL ETHER; METHYL 1 METHOXYINDOLE 3 CARBOXYLATE; PHYTOALEXIN; SINALEXIN; SPIROBRASSININ; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 0141761523     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey
Times cited : (70)

References (56)
  • 1
    • 0035798154 scopus 로고    scopus 로고
    • Involvement of the retinoblastoma (pRb)-E2F/DP pathway during antiproliferative effects of resveratrol in human epidermoid carcinoma (A431) cells
    • ADHAMI VM, AFAQ F, AHMAD N. Involvement of the retinoblastoma (pRb)-E2F/DP pathway during antiproliferative effects of resveratrol in human epidermoid carcinoma (A431) cells. Biochem Biophys Res Commun 2001; 288: 579-585.
    • (2001) Biochem Biophys Res Commun , vol.288 , pp. 579-585
    • Adhami, V.M.1    Afaq, F.2    Ahmad, N.3
  • 4
    • 0026066408 scopus 로고
    • Modulation of mycotoxin and nitrosamine carcinogenesis by indole-3-carbinol: Quantitation analysis of inhibition versus promotion
    • BAILEY GS, DASHWOOD RH, FONG AT, WILLIAMS DE. Modulation of mycotoxin and nitrosamine carcinogenesis by indole-3-carbinol: quantitation analysis of inhibition versus promotion. IARC Sci Publ 1991; 105: 275-280.
    • (1991) IARC Sci Publ , vol.105 , pp. 275-280
    • Bailey, G.S.1    Dashwood, R.H.2    Fong, A.T.3    Williams, D.E.4
  • 7
    • 0025776365 scopus 로고
    • Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice
    • BRADLOW HL, MICHNOVICZ J, TELANG NT, OSBORNE MP. Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice. Carcinogenesis (Lond.) 1991; 12: 1571-1574.
    • (1991) Carcinogenesis (Lond.) , vol.12 , pp. 1571-1574
    • Bradlow, H.L.1    Michnovicz, J.2    Telang, N.T.3    Osborne, M.P.4
  • 9
    • 0027254619 scopus 로고
    • New potential chemopreventive agents of azoxymethane induced foci of aberrant crypts in rat colon
    • CHUNG FL, MORSE MA, EKLIND KI, XU Y. New potential chemopreventive agents of azoxymethane induced foci of aberrant crypts in rat colon. Ann NY Acad Sci 1993; 686: 186-201.
    • (1993) Ann NY Acad Sci , vol.686 , pp. 186-201
    • Chung, F.L.1    Morse, M.A.2    Eklind, K.I.3    Xu, Y.4
  • 11
    • 0025057908 scopus 로고
    • Tumor dose response studies with aflatoxin B1 and the ambivalent modulator indole-3-carbinol: Inhibitory versus promotional potency
    • DASHWOOD RH, FONG AT, HENDRICKS JD, BAILEY GS. Tumor dose response studies with aflatoxin B1 and the ambivalent modulator indole-3-carbinol: inhibitory versus promotional potency. Basic Life Sci 1990; 52: 361-365.
    • (1990) Basic Life Sci , vol.52 , pp. 361-365
    • Dashwood, R.H.1    Fong, A.T.2    Hendricks, J.D.3    Bailey, G.S.4
  • 12
    • 0032111928 scopus 로고    scopus 로고
    • Pyrolidine dithiocarbamate activates the heat shock response and thereby induces apoptosis in primed endothelial cells
    • DEMEESTER SL, BUCHMAN TG, QIU Y, DUNNIGAN K, HOTCHKISS RS, KARL TE, COBB JP. Pyrolidine dithiocarbamate activates the heat shock response and thereby induces apoptosis in primed endothelial cells. Shock 1998; 10: 1-6.
    • (1998) Shock , vol.10 , pp. 1-6
    • Demeester, S.L.1    Buchman, T.G.2    Qiu, Y.3    Dunnigan, K.4    Hotchkiss, R.S.5    Karl, T.E.6    Cobb, J.P.7
  • 13
    • 0033036639 scopus 로고    scopus 로고
    • Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation
    • ELATTAR TM, VIRJI AS. Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation. Anticancer Drugs 1999; 10: 187-193.
    • (1999) Anticancer Drugs , vol.10 , pp. 187-193
    • Elattar, T.M.1    Virji, A.S.2
  • 14
    • 0030931522 scopus 로고    scopus 로고
    • Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens
    • FAHEY JW, ZHANG Y, TALALAY P. Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc Natl Acad Sci 1997; 94: 10367-10372.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 10367-10372
    • Fahey, J.W.1    Zhang, Y.2    Talalay, P.3
  • 15
    • 0010673102 scopus 로고    scopus 로고
    • Vilcacora [Uncaria tomentosa (Willd.) DC. and Uncaria guianensis (Aublet) Gmell.] - A review of published scientific literature
    • FALKIEWICZ B, LUKASIAK J. Vilcacora [Uncaria tomentosa (Willd.) DC. and Uncaria guianensis (Aublet) Gmell.] - a review of published scientific literature. Case Rep Clin Pract Rev 2001; 2: 305-316.
    • (2001) Case Rep Clin Pract Rev , vol.2 , pp. 305-316
    • Falkiewicz, B.1    Lukasiak, J.2
  • 19
    • 0031025733 scopus 로고    scopus 로고
    • Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes
    • GERHAUSER C, YOU M, LIU J, MORIARTY RM, HAWTHORNE M, MEHTA RG, MOON RC, PEZZUTO JM. Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes. Cancer Res 1997; 57: 272-278.
    • (1997) Cancer Res , vol.57 , pp. 272-278
    • Gerhauser, C.1    You, M.2    Liu, J.3    Moriarty, R.M.4    Hawthorne, M.5    Mehta, R.G.6    Moon, R.C.7    Pezzuto, J.M.8
  • 23
    • 0032735407 scopus 로고    scopus 로고
    • Effects of watercress consumption on urinary metabolites of nicotine in smokers
    • HECHT SS, CARMELLA SG, MURPHY SE. Effects of watercress consumption on urinary metabolites of nicotine in smokers. Cancer Epidemiol Biomarkers Prev 1999; 8: 907-913.
    • (1999) Cancer Epidemiol Biomarkers Prev , vol.8 , pp. 907-913
    • Hecht, S.S.1    Carmella, S.G.2    Murphy, S.E.3
  • 24
    • 0029563719 scopus 로고
    • Relationship between expression of topoisomerase II isoforms and intrinsic sensitivity to topoisomerase II inhibitors in breast cancer cell lines
    • HOULBROOK S, CARMICHAEL J, DAVIES S. Relationship between expression of topoisomerase II isoforms and intrinsic sensitivity to topoisomerase II inhibitors in breast cancer cell lines. Br J Cancer 1995; 72: 1454-1461.
    • (1995) Br J Cancer , vol.72 , pp. 1454-1461
    • Houlbrook, S.1    Carmichael, J.2    Davies, S.3
  • 26
    • 0031936553 scopus 로고    scopus 로고
    • Inhibition of aberrant proliferation and induction of apoptosis in pre-neoplastic human mammary epithelial cells by natural phytochemicals
    • KATDARE M, OSBORNE MP, TELANG NT. Inhibition of aberrant proliferation and induction of apoptosis in pre-neoplastic human mammary epithelial cells by natural phytochemicals. Oncol Rep 1998; 5: 311-315.
    • (1998) Oncol Rep , vol.5 , pp. 311-315
    • Katdare, M.1    Osborne, M.P.2    Telang, N.T.3
  • 27
    • 0031987248 scopus 로고    scopus 로고
    • Uncaria tomentosa (Willd.) DC. - Ethnomedicinal use and new pharmacological, toxicological and botanical results
    • KEPLINGER K, LAUS G, WURM M, DIETRICH MP, TAPPNER H. Uncaria tomentosa (Willd.) DC. - ethnomedicinal use and new pharmacological, toxicological and botanical results. J Ethnopharmacol 1999; 64: 23-34.
    • (1999) J Ethnopharmacol , vol.64 , pp. 23-34
    • Keplinger, K.1    Laus, G.2    Wurm, M.3    Dietrich, M.P.4    Tappner, H.5
  • 29
    • 0031855760 scopus 로고    scopus 로고
    • Induction of apoptosis by thiuramdisulfides, the reactive metabolites of dithiocarbamates, through coordinative modulation of NFκB c-fos/c-jun, and p53 proteins
    • LIU G-Y, FRANK N, BARTSCH H, LIN J-K. Induction of apoptosis by thiuramdisulfides, the reactive metabolites of dithiocarbamates, through coordinative modulation of NFκB c-fos/c-jun, and p53 proteins. Mol Carcinog 1998; 22: 235-246.
    • (1998) Mol Carcinog , vol.22 , pp. 235-246
    • Liu, G.-Y.1    Frank, N.2    Bartsch, H.3    Lin, J.-K.4
  • 30
    • 0034234254 scopus 로고    scopus 로고
    • Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IκB kinase
    • McNARY MH, BALDWIN AS JR. Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IκB kinase. Cancer Res 2000; 60: 3477-3483.
    • (2000) Cancer Res , vol.60 , pp. 3477-3483
    • McNary, M.H.1    Baldwin A.S., Jr.2
  • 31
    • 0030932743 scopus 로고    scopus 로고
    • Induction prevention of carcinogen-induced precancerous lesions in mouse mammary gland organ culture
    • MEHTA RG, HAWTHORNE ME, STEELE VE. Induction and prevention of carcinogen-induced precancerous lesions in mouse mammary gland organ culture. Methods Cell Sci 1997; 19: 19-24.
    • (1997) Methods Cell Sci , vol.19 , pp. 19-24
    • Mehta, R.G.1    Hawthorne, M.E.2    Steele, V.E.3
  • 33
    • 0028168218 scopus 로고
    • Structure-activity relationships of brassinin in preventing the development of carcinogen-induced mammary lesions in organ culture
    • MENTA RG, LIU J, CONSTANTINOU A, HAWTHORNE M, PEZZUTO JM, MOON RC, MORIARTY RM. Structure-activity relationships of brassinin in preventing the development of carcinogen-induced mammary lesions in organ culture. Anticancer Res 1994; 14: 1209-1214.
    • (1994) Anticancer Res , vol.14 , pp. 1209-1214
    • Menta, R.G.1    Liu, J.2    Constantinou, A.3    Hawthorne, M.4    Pezzuto, J.M.5    Moon, R.C.6    Moriarty, R.M.7
  • 34
    • 0025788487 scopus 로고
    • Influence of thiols and inhibitors of prostaglandin biosynthesis on the carcinogen-induced development of mammary lesions in vitro
    • MEHTA RG, STEELE V, KELLOFF CJ, MOON RC. Influence of thiols and inhibitors of prostaglandin biosynthesis on the carcinogen-induced development of mammary lesions in vitro. Anticancer Res 1991; 11: 587-592.
    • (1991) Anticancer Res , vol.11 , pp. 587-592
    • Mehta, R.G.1    Steele, V.2    Kelloff, C.J.3    Moon, R.C.4
  • 35
    • 0025741216 scopus 로고
    • Characterization of effective chemopreventive agents in mammary gland in vitro using an initiation-promotion protocol
    • MEHTA RG, MOON RC. Characterization of effective chemopreventive agents in mammary gland in vitro using an initiation-promotion protocol. Anticancer Res 1991; 11: 593-596.
    • (1991) Anticancer Res , vol.11 , pp. 593-596
    • Mehta, R.G.1    Moon, R.C.2
  • 36
    • 0031891466 scopus 로고    scopus 로고
    • Antiproliferative effect of synthetic resveratrol on human breast epithelial cells
    • MGBONYEBI OP, RUSSO J, RUSSO IH. Antiproliferative effect of synthetic resveratrol on human breast epithelial cells. Int J Oncol 1998; 12: 865-869.
    • (1998) Int J Oncol , vol.12 , pp. 865-869
    • Mgbonyebi, O.P.1    Russo, J.2    Russo, I.H.3
  • 37
    • 0025781767 scopus 로고
    • Altered estrogen metabolism and excretion in humans following consumption of indole-3-carbinol
    • MICHNOVICZ JJ, BRADLOW HL. Altered estrogen metabolism and excretion in humans following consumption of indole-3-carbinol. Nutr Cancer 1991; 16: 59-66.
    • (1991) Nutr Cancer , vol.16 , pp. 59-66
    • Michnovicz, J.J.1    Bradlow, H.L.2
  • 38
    • 0028060092 scopus 로고
    • Biosynthesis of cruciferous phytoalexins
    • MONDE K, TAKASUGI M, OHNISHI T. Biosynthesis of cruciferous phytoalexins. J Am Chem Soc 1994; 116: 6650-6657.
    • (1994) J Am Chem Soc , vol.116 , pp. 6650-6657
    • Monde, K.1    Takasugi, M.2    Ohnishi, T.3
  • 40
    • 0025809251 scopus 로고
    • A new topoisomerase-II inhibitor BE-10988, produced by a Streptomycete. I. Taxonomy, fermentation, isolation and characterization
    • OKA H, YOSHINARI T, MURAI T. A new topoisomerase-II inhibitor BE-10988, produced by a Streptomycete. I. Taxonomy, fermentation, isolation and characterization. J Antibiot 1991; 44: 486-491.
    • (1991) J Antibiot , vol.44 , pp. 486-491
    • Oka, H.1    Yoshinari, T.2    Murai, T.3
  • 41
    • 0033979455 scopus 로고    scopus 로고
    • Phytoalexins from crucifers: Synthesis, biosynthesis, and biotransformation
    • PEDRAS MSC, OKANGA FI, ZAHARIA IL, KHAN AQ. Phytoalexins from crucifers: synthesis, biosynthesis, and biotransformation. Phytochemistry 2000; 53: 161-176.
    • (2000) Phytochemistry , vol.53 , pp. 161-176
    • Pedras, M.S.C.1    Okanga, F.I.2    Zaharia, I.L.3    Khan, A.Q.4
  • 42
    • 0022494298 scopus 로고
    • Multiple dietary factors in the enhancement of dimethylhydrazine carcinogenesis: Main effects of indole-3-carbinol
    • PENCE BC, BUDDING F, YANG SP. Multiple dietary factors in the enhancement of dimethylhydrazine carcinogenesis: main effects of indole-3-carbinol. J Natl Cancer Inst 1986; 77: 269-276.
    • (1986) J Natl Cancer Inst , vol.77 , pp. 269-276
    • Pence, B.C.1    Budding, F.2    Yang, S.P.3
  • 43
    • 0027234043 scopus 로고
    • The French paradox: Dietary factors and cigarette smoking-related health risks
    • RENAUD S, DE LORGERIL M. The French paradox: dietary factors and cigarette smoking-related health risks. Ann N Y Acad Sci 1993; 686: 299-309.
    • (1993) Ann N Y Acad Sci , vol.686 , pp. 299-309
    • Renaud, S.1    De Lorgeril, M.2
  • 44
    • 0033215191 scopus 로고    scopus 로고
    • Report of the Chemoprevention Working Group to the American Association for Cancer Research. Prevention of cancer in the next millennium
    • Report of the Chemoprevention Working Group to the American Association for Cancer Research. Prevention of cancer in the next millennium. Cancer Res 1999; 59: 4743-4758.
    • (1999) Cancer Res , vol.59 , pp. 4743-4758
  • 45
    • 0023243941 scopus 로고
    • Coronary risk factors. The French paradox
    • RICHARD JL. Coronary risk factors. The French paradox. Arch Mal Coeur Vaiss 1987; 80: 17-21.
    • (1987) Arch Mal Coeur Vaiss , vol.80 , pp. 17-21
    • Richard, J.L.1
  • 47
    • 0030760030 scopus 로고    scopus 로고
    • Wine as a biological fluid: History, production, and role in disease prevention
    • SOLEAS GJ, DIAMANDIS EP, GOLDBERG DM. Wine as a biological fluid: history, production, and role in disease prevention. J Clin Lab Anal 1997; 11: 287-313.
    • (1997) J Clin Lab Anal , vol.11 , pp. 287-313
    • Soleas, G.J.1    Diamandis, E.P.2    Goldberg, D.M.3
  • 49
    • 0022919121 scopus 로고
    • Isolation of three novel sulphur containing phytoalexins from the chinese cabbage Brassica campestris L. ssp. pekinensis
    • TAKASUGI M, KATSUI M, SHIRATA A. Isolation of three novel sulphur containing phytoalexins from the chinese cabbage Brassica campestris L. ssp. pekinensis. J Chem Soc Chem Commun 1986; 23: 1077-1078.
    • (1986) J Chem Soc Chem Commun , vol.23 , pp. 1077-1078
    • Takasugi, M.1    Katsui, M.2    Shirata, A.3
  • 50
    • 0026184366 scopus 로고
    • Growth inhibition of human cancer cell cultures with the indole-sulphur containing phytoalexins and their analogs
    • TEMPTE C, DEVYS M, BARBIER M. Growth inhibition of human cancer cell cultures with the indole-sulphur containing phytoalexins and their analogs. Z Naturforsch 1991; 46c: 706-707.
    • (1991) Z Naturforsch , vol.46 C , pp. 706-707
    • Tempte, C.1    Devys, M.2    Barbier, M.3
  • 51
    • 0033023541 scopus 로고    scopus 로고
    • Suppression of nitric oxide synthase and the down-regulation of the activation of NF-κB in macrophages by resveratrol
    • TSAI SH, LIN-SHIAU SY, LIN JK. Suppression of nitric oxide synthase and the down-regulation of the activation of NF-κB in macrophages by resveratrol. Br J Pharmacol 1999; 126: 673-680.
    • (1999) Br J Pharmacol , vol.126 , pp. 673-680
    • Tsai, S.H.1    Lin-Shiau, S.Y.2    Lin, J.K.3
  • 53
    • 0029858387 scopus 로고    scopus 로고
    • TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappa B
    • WANG C-Y, MAYO MW, BALDWIN AS JR. TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappa B. Science 1996; 274: 784-787.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.-Y.1    Mayo, M.W.2    Baldwin A.S., Jr.3
  • 54
    • 0026590679 scopus 로고
    • Inhibition of carcinogenesis by minor dietary constituents
    • WATTENBERG LW. Inhibition of carcinogenesis by minor dietary constituents. Cancer Res 1992; 52: 2085-2091.
    • (1992) Cancer Res , vol.52 , pp. 2085-2091
    • Wattenberg, L.W.1
  • 55
    • 0021934758 scopus 로고
    • Chemoprevention of cancer
    • WATTENBERG LW. Chemoprevention of cancer. Cancer Res 1985; 45: 1-8.
    • (1985) Cancer Res , vol.45 , pp. 1-8
    • Wattenberg, L.W.1
  • 56
    • 0028326168 scopus 로고
    • Anticarcinogenic activities of organic isothiocyanates: Chemistry and mechanisms
    • ZHANG Y, TALALAY P. Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms. Cancer Res 1994; 54: 1976-1981.
    • (1994) Cancer Res , vol.54 , pp. 1976-1981
    • Zhang, Y.1    Talalay, P.2


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