High frequency of somatic mutations in rat liver mitochondrial DNA

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 685, Issue 1-2, 2010, Pages 97-102

  Rotskaya, Ulyana N ^a   Rogozin, Igor B ^a,b   Vasyunina, Elena A ^a   Malyarchuk, Boris A ^c   Nevinsky, Georgy A ^a,d   Sinitsyna, Olga I ^a  

^a INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c INSTITUTE OF BIOLOGICAL PROBLEMS OF THE NORTH   (Russian Federation)

^d INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

Author keywords

Age related somatic mutagenesis; Displacement loop; Mitochondrial DNA; Nucleotide substitutions; Wistar rats

Indexed keywords

ALANINE; CYSTEINE; DNA DIRECTED DNA POLYMERASE GAMMA; GLYCINE; MITOCHONDRIAL DNA; THREONINE;

AGE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; DNA SYNTHESIS; GENE POOL; MALE; MUTAGENESIS; MUTATION RATE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; REGULATOR GENE; SEQUENCE ANALYSIS; SOMATIC MUTATION; WISTAR RAT;

AGING; ANIMALS; BASE SEQUENCE; DNA, MITOCHONDRIAL; MALE; MITOCHONDRIA, LIVER; MOLECULAR SEQUENCE DATA; MUTATION; RATS; RATS, WISTAR;

RATTUS; RATTUS NORVEGICUS;

EID: 75749144976     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2009.12.010     Document Type: Article

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