Evaluation of a 64Cu-labeled cystine-knot peptide based on agouti-related protein for PET of tumors expressing αvβ 3 integrin

Journal of Nuclear Medicine

Volumn 51, Issue 2, 2010, Pages 251-258

  Jiang, Lei ^a,b   Kimura, Richard H ^b   Miao, Zheng ^b   Silverman, Adam P ^c   Ren, Gang ^b   Liu, Hongguang ^b   Li, Peiyong ^a   Gambhir, Sanjiv Sam ^b,c   Cochran, Jennifer R ^c   Cheng, Zhen ^b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

; v 3 integrin; 64Cu; Agouti related protein (AgRP); Cystine knot; PET

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID AGOUTI RELATED PROTEIN 7C CU 64; AGOUTI RELATED PROTEIN; BETA3 INTEGRIN; BINDING PROTEIN; CD51 ANTIGEN; COPPER 64; INTEGRIN; INTEGRIN RECEPTOR; MUTANT PROTEIN; RADIOISOTOPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL STRAIN; CELL STRAIN U87MG; CONTROLLED STUDY; CYSTINE KNOT MOTIF; DRUG UPTAKE; GLIOBLASTOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOTOPE LABELING; KIDNEY; LIVER; METABOLITE; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN STABILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID PHASE SYNTHESIS; TISSUE DISTRIBUTION; TUMOR DIAGNOSIS;

AGOUTI-RELATED PROTEIN; AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; COPPER RADIOISOTOPES; DRUG STABILITY; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; INTEGRIN ALPHAVBETA3; MICE; MICE, NUDE; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASMS; PEPTIDES; POSITRON-EMISSION TOMOGRAPHY; PROTEIN ENGINEERING; RADIOPHARMACEUTICALS; RECOMBINANT PROTEINS; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 75749091879     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.109.069831     Document Type: Article

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