Melanoma-targeting properties of 99mtechnetium-labeled cyclic α-melanocyte-stimulating hormone peptide analogues

Cancer Research

Volumn 60, Issue 20, 2000, Pages 5649-5658

  Chen, J Q ^a   Cheng, Z ^a   Hoffman, T J ^a   Jurisson, S S ^a   Quinn, T P ^a  

^a University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; ALPHA INTERMEDIN DERIVATIVE; ALPHA INTERMEDIN[3-13][3,4,10 CYSTEINE 7 PHENYLALANINE]; IODINE 125; LYSINE; NORLEUCINE; POLYPEPTIDE; TECHNETIUM 99M; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG UPTAKE; FEMALE; HUMAN; HUMAN CELL; ISOTOPE LABELING; MELANOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; TUMOR LOCALIZATION;

EID: 0034667352     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Basal cell and squamous cell carcinomas are important risk factors for cutaneous malignant melanoma
2. Systemic treatments for advanced cutaneous melanoma
3. Imaging of melanoma with I-131-labeled monoclonal antibodies
4. 2) anti-melanoma antibody fragments and single photon emission computed tomography
5. Immunoscintigraphy for ocular melanoma: A reliable diagnostic technique?
6. Intrapatient and interpatient comparison of tumor size and monoclonal antibody uptake in melanoma
7. Technetium-99m labeled monoclonal antibodies in the detection of metastatic melanoma
8. Pharmacokinetics of an indium-111-labeled IgG monoclonal antibody over a prolonged period
9. Effect of antibody dose on the imaging and biodistribution of In-111 9.2.27 anti-melanoma monoclonal antibody
10. Uptake kinetics of monoclonal antibodies by human melanoma multicell spheroids
11. Penetration and binding of antibodies in experimental human solid tumors grown in mice
12. Sequential use of indium-111 labeled monoclonal antibodies 96.5 and ZME-018 does not increase detection sensitivity of metastatic melanoma
13. 111In-DTPA-D-Phe)-octreotide for detection of somatostatin receptor-positive tumors in rat
14. A chelating derivative of α-melanocyte stimulating hormone as a potential imaging agent for malignant melanoma
15. Specific receptors for α-melanoma stimulating hormone are widely distributed in tissues of rodents
16. Characterization of receptors for α-melanocyte stimulating hormone on human melanoma cells
17. Melanotropin receptors demonstrated in situ in human melanoma
18. Cloning and functional characterization of a family of receptors for the melanotropin peptides
19. 4-Norleucine, 7-D-phenylalanine-α-melanocyte-stimulating hormone: A highly potent α-melanotropin with ultralong biological activity
20. Cyclic melanotropin 7-D-phenylalanine analogs of active-site sequence
21. Potent and prolonged acting cyclic lactam analogs of α-melanotropin: Design based on molecular dynamics
22. 2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors
23. Design and characterization of α-melanotropin peptide analogs cyclized though rhenium and technetium metal coordination
24. Receptor-mediated cytotoxicity of α-MSH fragments containing melphalan in a human melanoma cell line
25. Radio-receptor assay for α-MSH using mouse B16 melanoma cells
26. Enhanced binding and inertness to dehalogenation of α-melanotropin peptides labeled using N-succinimidyl 3-iodobenzoate
27. 7]-α-MSH, an α-melanocyte stimulating hormone analog
28. The use of a chelating derivative of α-melanocyte stimulating hormone for the clinical imaging of malignant melanoma
29. 111In-DPTA-labeled analogs of α-melanocyte-stimulating hormone for melanoma targeting: Receptor binding in vitro and in vivo
30. Synthesis and characterization of rhenium-complexed-melanotropin analogs
31. 188Re-labeled α melanocyte stimulating hormone analogs for specific melanoma targeting
32. 99mTc-labeled α-melanotropin peptides
33. Determination of the immunoreactive fraction of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess
34. Factors influencing the in vivo pharmacokinetics of peptides and antibody fragments: The pharmacokinetics of two PET-labeled low molecular weight proteins
35. Processing of antibody-radioisotope conjugates after binding to the surface of tumor cells
36. Targeted proteins for diagnostic imaging: Does chemistry make a difference?
37. Radiolabeling and biotinylation of internalizing monoclonal antibody chimeric BR96: Potential use for extracorporeal immunoadsorption with enhanced tumor radioactivity retention of iodine, indium and rhenium (Doctoral Dissertation)
38. 7]α-MSH in BI6 melanoma cells
39. Homologous and heterologous regulation of α-melanocyte-stimulating hormone receptor in human and mouse melanoma cell lines
40. Highly tumor-reactive, internalization, mouse monoclonal antibodies to Ley-related cell surface antigens