Sphingosine 1-phosphate induces vesicular endothelial growth factor expression in endothelial cells

BMB Reports

Volumn 42, Issue 10, 2009, Pages 685-690

  Heo, Kyun ^a,b   Park, Kyung A ^b   Kim, Yun Hee ^a   Kim, Sun Hee ^b   Oh, Yong Seok ^b   Kim, In Hoo ^a   Ryu, Sung Ho ^b   Suh, Pann Ghill ^b  

^a National Cancer Center   (South Korea)

^b Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

Angiogenesis; Endothelial cell; Promoter; Sphingosine 1 phosphate; Vascular endothelial cell growth factor

Indexed keywords

CALCIUM; DRUG DERIVATIVE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LYSOPHOSPHOLIPID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1-PHOSPHATE; TRANSCRIPTION FACTOR AP 1; VASCULOTROPIN A;

ANIMAL; ARTICLE; DRUG EFFECT; ENDOTHELIUM CELL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INTRACELLULAR SPACE; METABOLISM; MOUSE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CALCIUM; ENDOTHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HUMANS; INTRACELLULAR SPACE; LYSOPHOSPHOLIPIDS; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SPHINGOSINE; TRANSCRIPTION FACTOR AP-1; TYPE C PHOSPHOLIPASES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 75649087401     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2009.42.10.685     Document Type: Article

References (25)

1. Spiegel, S. and Milstien, S. (2003) Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat. Rev. Mol. Cell. Biol. 4, 397-407.
2. Yatomi, Y., Ohmori, T., Rile, G., Kazama, F., Okamoto, H., Sano, T., Satoh, K., Kume, S., Tigyi, G., Igarashi, Y. and Ozaki, Y.Y. (2001) Sphingosine 1-phosphate: synthesis and release. Prostaglandins Other Lipid Mediat. 64, 107-122.
3. Ito, K., Anada, Y., Tani, M., Ikeda, M., Sano, T., Kihara, A. and Igarashi, Y. (2007) Lack of sphingosine 1-phosphatedegrading enzymes in erythrocytes. Biochem. Biophys. Res. Commun. 357, 212-217.
4. Hanel, P., Andreani, P. and Graler, M. H. (2007) Erythrocytes store and release sphingosine 1-phosphate in blood. FASEB J. 21, 1202-1209.
5. Lee, M. J., Thangada, S., Claffey, K. P., Ancellin, N., Liu, C. H., Kluk, M., Volpi, M., Sha'afi, R. I. and Hla, T. (1999) Vascular endothelial cell Adherens Junction assembly and morphogenesis induced by sphingosine-1phosphate. Cell 99, 301-312.
6. Lee, M. J., Thangada, S., Paik, J. H., Gopal, S. P., Ancellin, N., Chan, S. S., Wu, M., Morales-Ruiz, M., Sessa, W. C., Alessi, D. and Hla, T. (2001) Akt-mediated phosphorylation of G protein-coupled receptor Edg-1 is required for endothelial cell chemotaxis. Mol. Cell 8, 693-704.
7. Lee, M. J., VanBrocklyn, J. R., Thangada, S., Liu, C. H., Hand, A. R., Menzeleev, R., Spiegel, S. and Hla, T. (1998) Sphngosine-1-phosphate as a ligand for the protein-coupled receptor EDG-l. Science 279, 1552-1555.
8. Visentin, B., Vekich, J. A., Sibbald, B. J., Cavalli, A. L., Moreno, K. M., Matteo, R. G., Garland, W. A., Lu, Y., Yu, S., Hall, H. S., Kundra, V., Mills, G. B. and Sabbadini, R. A. (2006) Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages. Cancer Cell 9, 225-238.
9. Chae, S. S., Paik, J. H., Furneaux, H. and Hla, T. (2004) Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference. J. Clin. Invest. 114, 1082-1089.
10. Ferrara, N. (2004) Vascular endothelial growth factor: basic science and clinical progress. Endocr. Rev. 25, 581-611.
11. Mukhopadhyay, D., Zeng, H. and Bhattacharya, R. (2004) Complexity in the vascular permeability factor/vascular endothelial growth factor (VPF/VEGF)-receptors signaling. Mol. Cell. Biochem. 264, 51-61.
12. Pages, G. and Pouyssegur, J. (2005) Transcriptional regulation of the vascular endothelial growth factor gene--a concert of activating factors. Cardiovasc. Res. 65, 564-573.
13. Levy, N. S., Chung, S., Furneaux, H. and Levy, A. P. (1998) Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR. J. Biol. Chem. 273. 6417-6423.
14. Ellis, L. M. and Hicklin, D. J. (2008) VEGF-targeted therapy: mechanisms of anti-tumour activity. Nat. Rev. Cancer 8, 579-591.
15. Shibuya, M. (2006) Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis. J. Biochem. Mol. Biol. 39, 469-478.
16. Sanchez, T. and Hla, T. (2004) Structural and functional characteristics of S1P receptors. J. Cell. Biochem. 92, 913-922.
17. Hu, Y. L., Albanese, C., Pestell, R. G. and Jaffe, R. B. (2003) Dual mechanisms for lysophosphatidic acid stimulation of human ovarian carcinoma cells. J. Natl.Cancer Inst. 95, 733-740.
18. Kim, J. H., Kim, J. H., Song, W. K., Kim, J. H. and Chun, J. S. (2000) Sphingosine 1-phosphate activates Erk-1/-2 by transactivating epidermal growth factor receptor in rat-2 cells. IUBMB Life 50, 119-124.
19. Daub, H., Wallasch, C., Lankenau, A., Herrlich, A. and Ullrich, A. (1997) Signal characteristics of G protein-transactivated EGF receptor. EMBO J. 16, 7032-7044.
20. Dery, M. A. Michaud, M. D. and Richard, D. E. (2005) Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators. Int. J. Biochem. Cell Biol. 37, 535-540.
21. Clifford, R. L., Deacon, K. and Knox, A. J. (2008) Novel regulation of vascular endothelial growth factor-A (VEGF-A) by TGFbeta 1: requirement for smads, beta-catenin and GSK3beta. J. Biol. Chem. 283, 35337-35353.
22. Ristimaki, A., Narko, K., Enholm, B., Joukov, V. and Alitalo, K. (1998) Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C. J. Biol. Chem. 273, 8413-8418.
23. Lin, C. I., Chen, C. N., Huang, M. T., Lee, S. J., Lin, C. H., Chang, C. C. and Lee, H. (2008) Lysophosphatidic acid up-regulates vascular endothelial growth factor-C and lymphatic marker expressions in human endothelial cells. Cell. Mol. Life Sci. 65, 2740-2751.
24. Ancuta, P., Rao, R., Moses, A., Mehle, A., Shaw, S. K., Luscinskas, W. and Gabuzda, D. (2003) J. Exp. Med. 197, 1701-1707.
25. Lim, S., Choi, J. W., Kim, H. S., Kim, Y. H., Yea, K., Heo, K., Kim, J. H., Kim, S. H., Song, M., Kim, J. I., Ryu, S. H. and Suh, P. G. (2008) A myristoylated pseudosubstrate peptide of PKC-zeta induces degranulation in HMC-1 cells independently of PKC-zeta activity. Life Sci. 82, 733-740.