-
1
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J: Tumor angiogenesis: Therapeutic implications. New Engl J Med 285: 1182-1186, 1971
-
(1971)
New Engl. J. Med.
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
2
-
-
0024549349
-
Induction of angiogenesis during the transition from hyperplasia to neoplasia
-
Folkman J, Watson K, Ingber D, Hanahan D: Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 339: 58-61, 1989
-
(1989)
Nature
, vol.339
, pp. 58-61
-
-
Folkman, J.1
Watson, K.2
Ingber, D.3
Hanahan, D.4
-
3
-
-
0023157363
-
Angiogenic factors
-
Folkman J, Klagsbrun M: Angiogenic factors. Science 235: 442-447, 1987
-
(1987)
Science
, vol.235
, pp. 442-447
-
-
Folkman, J.1
Klagsbrun, M.2
-
4
-
-
0030242225
-
Fighting cancer by attacking its blood supply
-
Folkman J: Fighting cancer by attacking its blood supply. Sci Am 275: 150-154, 1996
-
(1996)
Sci. Am.
, vol.275
, pp. 150-154
-
-
Folkman, J.1
-
5
-
-
0032889698
-
Vascular pelmeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis
-
Dvorak HF, Nagy JA, Feng D, Brown LF, Dvorak AM: Vascular pelmeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis. Curr Top Microbiol Immunol 237: 97-132, 1999
-
(1999)
Curr. Top. Microbiol. Immunol.
, vol.237
, pp. 97-132
-
-
Dvorak, H.F.1
Nagy, J.A.2
Feng, D.3
Brown, L.F.4
Dvorak, A.M.5
-
6
-
-
0030952289
-
Mechanisms of angiogenesis
-
Risau W: Mechanisms of angiogenesis. Nature 386: 671-674, 1997
-
(1997)
Nature
, vol.386
, pp. 671-674
-
-
Risau, W.1
-
7
-
-
0027198859
-
Thrombin-induced release of active basic fibroblast growth factor-heparan sulfate complexes from subendothelial extracellular matrix
-
Benezra M, Vlodavsky I, Ishai-Michaeli R, Neufeld G, Bar-Shavit R: Thrombin-induced release of active basic fibroblast growth factor-heparan sulfate complexes from subendothelial extracellular matrix. Blood 81: 3324-3331, 1993
-
(1993)
Blood
, vol.81
, pp. 3324-3331
-
-
Benezra, M.1
Vlodavsky, I.2
Ishai-Michaeli, R.3
Neufeld, G.4
Bar-Shavit, R.5
-
8
-
-
0023039225
-
A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines
-
Senger DR, Perruzzi CA, Feder J, Dvorak HF: A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines. Cancer Res 46: 5629-5632, 1986
-
(1986)
Cancer Res.
, vol.46
, pp. 5629-5632
-
-
Senger, D.R.1
Perruzzi, C.A.2
Feder, J.3
Dvorak, H.F.4
-
9
-
-
0026065140
-
Extracellular matrix-resident basic fibroblast growth factor: Implication for the control of angiogenesis
-
Vlodavsky I, Fuks Z, Ishai-Michaeli R, Bashkin P, Levi E, Korner G, Bar-Shavit R, Klagsbrun M: Extracellular matrix-resident basic fibroblast growth factor: Implication for the control of angiogenesis. J Cell Biochem 45: 167-176, 1991
-
(1991)
J. Cell Biochem.
, vol.45
, pp. 167-176
-
-
Vlodavsky, I.1
Fuks, Z.2
Ishai-Michaeli, R.3
Bashkin, P.4
Levi, E.5
Korner, G.6
Bar-Shavit, R.7
Klagsbrun, M.8
-
10
-
-
0018304899
-
Induction of a fibrin-gel investment: An early event in line 10 hepatocarcinoma growth mediated by tumor-secreted products
-
Dvorak HF, Orenstein NS, Carvalho AC, Churchill WH, Dvorak AM, Galli SJ, Feder J, Bitzer AM, Rypysc J, Giovinco P: Induction of a fibrin-gel investment: An early event in line 10 hepatocarcinoma growth mediated by tumor-secreted products. J Immunol 122: 166-174, 1979
-
(1979)
J. Immunol.
, vol.122
, pp. 166-174
-
-
Dvorak, H.F.1
Orenstein, N.S.2
Carvalho, A.C.3
Churchill, W.H.4
Dvorak, A.M.5
Galli, S.J.6
Feder, J.7
Bitzer, A.M.8
Rypysc, J.9
Giovinco, P.10
-
11
-
-
0021152778
-
Quantitation of fibrinogen influx and fibrin deposition and turnover in line 1 and line 10 guinea pig carcinomas
-
Dvorak HF, Harvey VS, McDonagh J: Quantitation of fibrinogen influx and fibrin deposition and turnover in line 1 and line 10 guinea pig carcinomas. Cancer Res 44: 3348-3354, 1984
-
(1984)
Cancer Res.
, vol.44
, pp. 3348-3354
-
-
Dvorak, H.F.1
Harvey, V.S.2
McDonagh, J.3
-
12
-
-
0025653869
-
Leaky tumor vessels: Consequences for tumor stroma generation and for solid tumor therapy
-
Dvorak HF: Leaky tumor vessels: Consequences for tumor stroma generation and for solid tumor therapy. Prog Clin Biol Res 354A: 317-330, 1990
-
(1990)
Prog. Clin. Biol. Res.
, vol.354
, pp. 317-330
-
-
Dvorak, H.F.1
-
13
-
-
0032890051
-
Vascular endothelial growth factor: Molecular and biological aspects
-
Ferrara N: Vascular endothelial growth factor: Molecular and biological aspects. Curr Top Microbiol Immunol 237: 1-30, 1999
-
(1999)
Curr. Top Microbiol. Immunol.
, vol.237
, pp. 1-30
-
-
Ferrara, N.1
-
14
-
-
0041440927
-
Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: An autocrine mechanism contributing to angiogenesis
-
Seghezzi G, Patel S, Ren CJ, Gualandris A, Pintucci G, Robbins ES, Shapiro RL, Galloway AC, Rifkin DB, Mignatti P: Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: An autocrine mechanism contributing to angiogenesis. J Cell Biol 141: 1659-1673, 1998
-
(1998)
J. Cell Biol.
, vol.141
, pp. 1659-1673
-
-
Seghezzi, G.1
Patel, S.2
Ren, C.J.3
Gualandris, A.4
Pintucci, G.5
Robbins, E.S.6
Shapiro, R.L.7
Galloway, A.C.8
Rifkin, D.B.9
Mignatti, P.10
-
15
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
Leung DW, Cachianes G, Kuang W-J, Goeddel DV, Ferrara N: Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246: 1306-1309, 1989
-
(1989)
Science
, vol.246
, pp. 1306-1309
-
-
Leung, D.W.1
Cachianes, G.2
Kuang, W.-J.3
Goeddel, D.V.4
Ferrara, N.5
-
16
-
-
0021111648
-
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
-
Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF: Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219: 983-985, 1983
-
(1983)
Science
, vol.219
, pp. 983-985
-
-
Senger, D.R.1
Galli, S.J.2
Dvorak, A.M.3
Perruzzi, C.A.4
Harvey, V.S.5
Dvorak, H.F.6
-
17
-
-
0033638730
-
Functions of the VEGF/VEGF receptor system in the vascular system
-
Breier G: Functions of the VEGF/VEGF receptor system in the vascular system. Semin Thromb Hemost 26: 553-559, 2000
-
(2000)
Semin. Thromb. Hemost.
, vol.26
, pp. 553-559
-
-
Breier, G.1
-
18
-
-
0037350079
-
Cardiac myofibroblasts: A novel source of vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR
-
Chintalgattu V, Nair DM, Katwa LC: Cardiac myofibroblasts: A novel source of vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR. J Mol Cell Cardiol 35: 277-286, 2003
-
(2003)
J. Mol. Cell Cardiol.
, vol.35
, pp. 277-286
-
-
Chintalgattu, V.1
Nair, D.M.2
Katwa, L.C.3
-
19
-
-
0036444240
-
Contribution of marrow-derived progenitors to vascular and cardiac regeneration
-
Rafii S, Meeus S, Dias S, Hattori K, Heissig B, Shmelkov S, Rafii D, Lyden D: Contribution of marrow-derived progenitors to vascular and cardiac regeneration. Semin Cell Dev Biol 13: 61-67, 2002
-
(2002)
Semin. Cell Dev. Biol.
, vol.13
, pp. 61-67
-
-
Rafii, S.1
Meeus, S.2
Dias, S.3
Hattori, K.4
Heissig, B.5
Shmelkov, S.6
Rafii, D.7
Lyden, D.8
-
20
-
-
0036344496
-
Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment
-
Hattori K, Heissig B, Wu Y, Dias S, Tejada R, Ferris B, Hicklin DJ, Zhu Z, Bohlen P, Witte L, Hendrikx J, Hackett NR, Crystal RG, Moore MA, Werb Z, Lyden D, Rafii S: Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment. Nat Med 8: 841-849, 2002
-
(2002)
Nat. Med.
, vol.8
, pp. 841-849
-
-
Hattori, K.1
Heissig, B.2
Wu, Y.3
Dias, S.4
Tejada, R.5
Ferris, B.6
Hicklin, D.J.7
Zhu, Z.8
Bohlen, P.9
Witte, L.10
Hendrikx, J.11
Hackett, N.R.12
Crystal, R.G.13
Moore, M.A.14
Werb, Z.15
Lyden, D.16
Rafii, S.17
-
21
-
-
0036344816
-
VEGF receptor 1 stimulates stem-cell recruitment and new hope for angiogenesis therapies
-
Eriksson U, Alitalo K: VEGF receptor 1 stimulates stem-cell recruitment and new hope for angiogenesis therapies. Nat Med 8: 775-777, 2002
-
(2002)
Nat. Med.
, vol.8
, pp. 775-777
-
-
Eriksson, U.1
Alitalo, K.2
-
22
-
-
0036896566
-
Recent progress in gene therapy for cardiovascular disease
-
Morishita R: Recent progress in gene therapy for cardiovascular disease. Circ J 66: 1077-1086, 2002
-
(2002)
Circ. J.
, vol.66
, pp. 1077-1086
-
-
Morishita, R.1
-
23
-
-
0037418035
-
Prognostic significance of angiogenic growth factor serum levels in patients with acute coronary syndromes
-
Heeschen C, Dimmeler S, Hamm CW, Boersma E, Zeiher AM, Simoons ML: Prognostic significance of angiogenic growth factor serum levels in patients with acute coronary syndromes. Circulation 107: 524-530, 2003
-
(2003)
Circulation
, vol.107
, pp. 524-530
-
-
Heeschen, C.1
Dimmeler, S.2
Hamm, C.W.3
Boersma, E.4
Zeiher, A.M.5
Simoons, M.L.6
-
24
-
-
0037453099
-
The VIVA trial: Vascular endothelial growth factor in ischemia for vascular angiogenesis
-
Henry TD, Annex BH, McKendall GR, Azrin MA, Lopez JJ, Giordano FJ, Shah PK, Willerson JT, Benza RL, Berman DS, Gibson CM, Bajamonde A, Rundle AC, Fine J, McCluskey ER: The VIVA trial: Vascular endothelial growth factor in ischemia for vascular angiogenesis. Circulation 107: 1359-1365, 2003
-
(2003)
Circulation
, vol.107
, pp. 1359-1365
-
-
Henry, T.D.1
Annex, B.H.2
McKendall, G.R.3
Azrin, M.A.4
Lopez, J.J.5
Giordano, F.J.6
Shah, P.K.7
Willerson, J.T.8
Benza, R.L.9
Berman, D.S.10
Gibson, C.M.11
Bajamonde, A.12
Rundle, A.C.13
Fine, J.14
McCluskey, E.R.15
-
25
-
-
0036892770
-
Vascular growth factors for coronary angiogenesis
-
Lee CH, Smits PC: Vascular growth factors for coronary angiogenesis. J Interv Cardiol 15: 511-518, 2002
-
(2002)
J. Interv. Cardiol.
, vol.15
, pp. 511-518
-
-
Lee, C.H.1
Smits, P.C.2
-
26
-
-
0035173338
-
Therapeutic angiogenesis in critical limb and myocardial ischemia
-
Vale PR, Isner JM, Rosenfield K: Therapeutic angiogenesis in critical limb and myocardial ischemia. J Interv Cardiol 14: 511-528, 2001
-
(2001)
J. Interv. Cardiol.
, vol.14
, pp. 511-528
-
-
Vale, P.R.1
Isner, J.M.2
Rosenfield, K.3
-
27
-
-
0037297359
-
Gene therapy progress and prospects: Therapeutic angiogenesis for limb and myocardial ischemia
-
Khan TA, Sellke FW, Laham RJ: Gene therapy progress and prospects: Therapeutic angiogenesis for limb and myocardial ischemia. Gene Ther 10: 285-291, 2003
-
(2003)
Gene Ther.
, vol.10
, pp. 285-291
-
-
Khan, T.A.1
Sellke, F.W.2
Laham, R.J.3
-
28
-
-
85026141318
-
Gene therapy with vascular endothelial growth factor reduces angina
-
Merkle CJ, Montgomery DW: Gene therapy with vascular endothelial growth factor reduces angina. J Cardiovasc Nurs 18: 38-43, 2003
-
(2003)
J. Cardiovasc. Nurs.
, vol.18
, pp. 38-43
-
-
Merkle, C.J.1
Montgomery, D.W.2
-
29
-
-
0029021660
-
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
-
Fong GH, Rossant J, Gertsenstein M, Breitman ML: Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376: 66-70, 1995
-
(1995)
Nature
, vol.376
, pp. 66-70
-
-
Fong, G.H.1
Rossant, J.2
Gertsenstein, M.3
Breitman, M.L.4
-
30
-
-
0027466849
-
High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
-
Millauer B, Wizigmann-Voos S, Schnurch H, Martinez R, Meller NPH, Risau W, Ullrich A: High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72: 835-846, 1993
-
(1993)
Cell
, vol.72
, pp. 835-846
-
-
Millauer, B.1
Wizigmann-Voos, S.2
Schnurch, H.3
Martinez, R.4
Meller, N.P.H.5
Risau, W.6
Ullrich, A.7
-
31
-
-
0027249239
-
Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium
-
Quinn TP, Peters KG, De Vries C, Ferrara N, Williams LT: Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc Natl Acad Sci USA 90: 7533-7537, 1993
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7533-7537
-
-
Quinn, T.P.1
Peters, K.G.2
De Vries, C.3
Ferrara, N.4
Williams, L.T.5
-
32
-
-
0030831104
-
A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis
-
Shalaby F, Ho J, Stanford WL, Fischer KD, Schuh AC, Schwartz L, Bernstein A, Rossant J: A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell 89: 981-990, 1997
-
(1997)
Cell
, vol.89
, pp. 981-990
-
-
Shalaby, F.1
Ho, J.2
Stanford, W.L.3
Fischer, K.D.4
Schuh, A.C.5
Schwartz, L.6
Bernstein, A.7
Rossant, J.8
-
33
-
-
0026702970
-
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
-
Terman B, Dougher-Vermazen M, Carrion M, Dimitrov D, Almellino D, Gospodarowicz D, Bohlen P: Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun 187: 1579-1586, 1992
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.187
, pp. 1579-1586
-
-
Terman, B.1
Dougher-Vermazen, M.2
Carrion, M.3
Dimitrov, D.4
Almellino, D.5
Gospodarowicz, D.6
Bohlen, P.7
-
34
-
-
0034646262
-
Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity
-
Gagnon ML, Bielenberg DR, Gechtman Z, Miao HQ, Takashima S, Soker S, Klagsbrun M: Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity. Proc Natl Acad Sci USA 97: 2573-2578, 2000
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2573-2578
-
-
Gagnon, M.L.1
Bielenberg, D.R.2
Gechtman, Z.3
Miao, H.Q.4
Takashima, S.5
Soker, S.6
Klagsbrun, M.7
-
35
-
-
0032549799
-
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
-
Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M: Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92: 735-745, 1998
-
(1998)
Cell
, vol.92
, pp. 735-745
-
-
Soker, S.1
Takashima, S.2
Miao, H.Q.3
Neufeld, G.4
Klagsbrun, M.5
-
37
-
-
0031011529
-
Proteolytic processing regulates receptor specificity and activity of VEGF-C
-
Joukov V, Sorsa T, Kumar V, Jeltsch M, Claesson-Welsh L, Cao Y, Saksela O, Kalkkinen N, Alitalo K: Proteolytic processing regulates receptor specificity and activity of VEGF-C. EMBO J 16: 3898-3911, 1997
-
(1997)
EMBO J.
, vol.16
, pp. 3898-3911
-
-
Joukov, V.1
Sorsa, T.2
Kumar, V.3
Jeltsch, M.4
Claesson-Welsh, L.5
Cao, Y.6
Saksela, O.7
Kalkkinen, N.8
Alitalo, K.9
-
38
-
-
0027997863
-
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor
-
Waltenberger J, Claesson-Welsh L, Siegbahn A, Shibuya M, Heldin CH: Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J Biol Chem 269: 26988-26995, 1994
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26988-26995
-
-
Waltenberger, J.1
Claesson-Welsh, L.2
Siegbahn, A.3
Shibuya, M.4
Heldin, C.H.5
-
39
-
-
0033604614
-
Signaling via vascular endothelial growth factor receptors
-
Petrova TV, Makinen T, Alitalo K: Signaling via vascular endothelial growth factor receptors. Exp Cell Res 253: 117-130, 1999
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 117-130
-
-
Petrova, T.V.1
Makinen, T.2
Alitalo, K.3
-
40
-
-
0029006696
-
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
-
Shalaby F, Rossant J, Yamaguchi TP, Gertsenstein M, Wu XF, Breitman ML, Schuh AC: Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376: 62-66, 1995
-
(1995)
Nature
, vol.376
, pp. 62-66
-
-
Shalaby, F.1
Rossant, J.2
Yamaguchi, T.P.3
Gertsenstein, M.4
Wu, X.F.5
Breitman, M.L.6
Schuh, A.C.7
-
41
-
-
0026572345
-
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
-
de Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT: The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255: 989-991, 1992
-
(1992)
Science
, vol.255
, pp. 989-991
-
-
de Vries, C.1
Escobedo, J.A.2
Ueno, H.3
Houck, K.4
Ferrara, N.5
Williams, L.T.6
-
42
-
-
0036530222
-
Vascular endothelial growth factor receptor Flt-1 negatively regulates developmental blood vessel formation by modulating endothelial cell division
-
Kearney JB, Ambler CA, Monaco KA, Johnson N, Rapoport RG, Bautch VL: Vascular endothelial growth factor receptor Flt-1 negatively regulates developmental blood vessel formation by modulating endothelial cell division. Blood 99: 2397-2407, 2002
-
(2002)
Blood
, vol.99
, pp. 2397-2407
-
-
Kearney, J.B.1
Ambler, C.A.2
Monaco, K.A.3
Johnson, N.4
Rapoport, R.G.5
Bautch, V.L.6
-
43
-
-
0033604557
-
New insights into the control of MAP kinase pathways
-
English J, Pearson G, Wilsbacher J, Swantek J, Karandikar M, Xu S, Cobb MH: New insights into the control of MAP kinase pathways. Exp Cell Res 253: 255-270, 1999
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 255-270
-
-
English, J.1
Pearson, G.2
Wilsbacher, J.3
Swantek, J.4
Karandikar, M.5
Xu, S.6
Cobb, M.H.7
-
45
-
-
0035920244
-
Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) peceptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways
-
Zeng H, Dvorak HF, Mukhopadhyay D: Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) peceptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways. J Biol Chem 276: 26969-26979, 2001
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 26969-26979
-
-
Zeng, H.1
Dvorak, H.F.2
Mukhopadhyay, D.3
-
46
-
-
0035980051
-
Tyrosine residues 951 and 1059 of vascular endothelial growth factor receptor-2 (KDR) are essential for vascular permeability factor/vascular endothelial growth factor-induced endothelium migration and proliferation, respectively
-
Zeng H, Sanyal S, Mukhopadhyay D: Tyrosine residues 951 and 1059 of vascular endothelial growth factor receptor-2 (KDR) are essential for vascular permeability factor/vascular endothelial growth factor-induced endothelium migration and proliferation, respectively. J Biol Chem 276: 32714-32719, 2001
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32714-32719
-
-
Zeng, H.1
Sanyal, S.2
Mukhopadhyay, D.3
-
47
-
-
0034051161
-
VRAP is an adaptor protein that binds KDR, a receptor for vascular endothelial cell growth factor
-
Wu LW, Mayo LD, Dunbar JD, Kessler KM, Ozes ON, Warren RS, Donner DB: VRAP is an adaptor protein that binds KDR, a receptor for vascular endothelial cell growth factor. J Biol Chem 275: 6059-6062, 2000
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6059-6062
-
-
Wu, L.W.1
Mayo, L.D.2
Dunbar, J.D.3
Kessler, K.M.4
Ozes, O.N.5
Warren, R.S.6
Donner, D.B.7
-
48
-
-
0028899424
-
Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation
-
Guo D, Jia Q, Song HY, Warren RS, Donner DB: Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation. J Biol Chem 270: 6729-6733, 1995
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 6729-6733
-
-
Guo, D.1
Jia, Q.2
Song, H.Y.3
Warren, R.S.4
Donner, D.B.5
-
49
-
-
0030995012
-
Regulation of phosphoinositide-specific phospholipase C isozymes
-
Rhee SG, Bae YS: Regulation of phosphoinositide-specific phospholipase C isozymes. J Biol Chem 272: 15045-15048, 1997
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15045-15048
-
-
Rhee, S.G.1
Bae, Y.S.2
-
50
-
-
0026728169
-
G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding
-
Mukai H, Munekata E, Higashijima T: G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J Biol Chem 267: 16237-16243, 1992
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 16237-16243
-
-
Mukai, H.1
Munekata, E.2
Higashijima, T.3
-
51
-
-
0032721216
-
Angiotensin II-stimulated induction of sis-inducing factor is mediated by pertussis toxin-insensitive G(q) proteins in cardiac myocytes
-
Hunt RA, Bhat GJ, Baker KM: Angiotensin II-stimulated induction of sis-inducing factor is mediated by pertussis toxin-insensitive G(q) proteins in cardiac myocytes. Hypertension 34: 603-608, 1999
-
(1999)
Hypertension
, vol.34
, pp. 603-608
-
-
Hunt, R.A.1
Bhat, G.J.2
Baker, K.M.3
-
52
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse
-
Schwarze SR, Ho A, Vocero-Akbani A, Dowdy SF: In vivo protein transduction: Delivery of a biologically active protein into the mouse. Science 285: 1569-1572, 1999
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
53
-
-
0035266403
-
The 104-123 amino acid sequence of the beta-domain of von Hippel-Lindau gene product is sufficient to inhibit renal tumor growth and invasion
-
Datta K, Sundberg C, Karumanchi SA, Mukhopadhyay D: The 104-123 amino acid sequence of the beta-domain of von Hippel-Lindau gene product is sufficient to inhibit renal tumor growth and invasion. Cancer Res 61: 1768-1775, 2001
-
(2001)
Cancer Res.
, vol.61
, pp. 1768-1775
-
-
Datta, K.1
Sundberg, C.2
Karumanchi, S.A.3
Mukhopadhyay, D.4
-
54
-
-
0026059418
-
Thrombin inhibits the pertussis-toxin-dependent ADP-ribosylation of a novel soluble Gi-protein in human platelets
-
Gennity J, Siess W: Thrombin inhibits the pertussis-toxin-dependent ADP-ribosylation of a novel soluble Gi-protein in human platelets. Biochem J 279: 643-650, 1991
-
(1991)
Biochem. J.
, vol.279
, pp. 643-650
-
-
Gennity, J.1
Siess, W.2
-
55
-
-
0030018304
-
A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2
-
Takata M, Kurosaki T: A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2. J Exp Med 184: 31-40, 1996
-
(1996)
J. Exp. Med.
, vol.184
, pp. 31-40
-
-
Takata, M.1
Kurosaki, T.2
-
56
-
-
0033118228
-
VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells
-
Takahashi T, Ueno H, Shibuya M: VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells. Oncogene 18: 2221-2230, 1999
-
(1999)
Oncogene
, vol.18
, pp. 2221-2230
-
-
Takahashi, T.1
Ueno, H.2
Shibuya, M.3
-
57
-
-
0032562289
-
Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy
-
Akhter SA, Luttrell LM, Rockman HA, Iaccarino G, Lefkowitz RJ, Koch WJ: Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science 280: 574-577, 1998
-
(1998)
Science
, vol.280
, pp. 574-577
-
-
Akhter, S.A.1
Luttrell, L.M.2
Rockman, H.A.3
Iaccarino, G.4
Lefkowitz, R.J.5
Koch, W.J.6
-
58
-
-
0028085776
-
Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling
-
Koch WJ, Hawes BE, Inglese J, Luttrel LM, Lefkowitz RJ: Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling. J Biol Chem 269: 6193-6197, 1994
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 6193-6197
-
-
Koch, W.J.1
Hawes, B.E.2
Inglese, J.3
Luttrel, L.M.4
Lefkowitz, R.J.5
-
59
-
-
0034690028
-
Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells
-
Kanno S, Oda N, Abe M, Terai Y, Ito M, Shitara K, Tabayashi K, Shibuya M, Sato Y: Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells. Oncogene 19: 2138-2146, 2000
-
(2000)
Oncogene
, vol.19
, pp. 2138-2146
-
-
Kanno, S.1
Oda, N.2
Abe, M.3
Terai, Y.4
Ito, M.5
Shitara, K.6
Tabayashi, K.7
Shibuya, M.8
Sato, Y.9
-
60
-
-
0032720628
-
Vascular endothelial growth factor effect on endothelial cell proliferation, migration, and platelet-activating factor synthesis is Flk-1-dependent
-
Bernatchez PN, Soker S, Sirois MG: Vascular endothelial growth factor effect on endothelial cell proliferation, migration, and platelet-activating factor synthesis is Flk-1-dependent. J Biol Chem 274: 31047-31054, 1999
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31047-31054
-
-
Bernatchez, P.N.1
Soker, S.2
Sirois, M.G.3
-
61
-
-
0034254273
-
A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3′-kinase activation and endothelial cell migration
-
Gille H, Kowalski J, Yu L, Chen H, Pisabarro MT, Davis-Smyth T, Ferrara N: A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3′-kinase activation and endothelial cell migration. EMBO J 19: 4064-4073, 2000
-
(2000)
EMBO J.
, vol.19
, pp. 4064-4073
-
-
Gille, H.1
Kowalski, J.2
Yu, L.3
Chen, H.4
Pisabarro, M.T.5
Davis-Smyth, T.6
Ferrara, N.7
-
62
-
-
0035793623
-
Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants
-
Gille H, Kowalski J, Li B, LeCouter J, Moffat B, Zioncheck TF, Pelletier N, Ferrara N: Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants. J Biol Chem 276: 3222-3230, 2001
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3222-3230
-
-
Gille, H.1
Kowalski, J.2
Li, B.3
LeCouter, J.4
Moffat, B.5
Zioncheck, T.F.6
Pelletier, N.7
Ferrara, N.8
-
63
-
-
0029047382
-
Interaction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding
-
Cunningham SA, Waxham MN, Arrate PM, Brock TA: Interaction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding. J Biol Chem 270: 20254-20257, 1995
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20254-20257
-
-
Cunningham, S.A.1
Waxham, M.N.2
Arrate, P.M.3
Brock, T.A.4
-
64
-
-
0033574429
-
Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110 alpha submit of phosphoinositide 3-kinase
-
Bi L, Okabe I, Bernard DJ, Wynshaw-Boris A, Nussbaum RL: Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110 alpha submit of phosphoinositide 3-kinase. J Biol Chem 274: 10963-10968, 1999
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10963-10968
-
-
Bi, L.1
Okabe, I.2
Bernard, D.J.3
Wynshaw-Boris, A.4
Nussbaum, R.L.5
-
65
-
-
0032482978
-
Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
-
Hiratsuka S, Minowa O, Kuno J, Noda T, Shibuya M: Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc Natl Acad Sci USA 95: 9349-9354, 1998
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9349-9354
-
-
Hiratsuka, S.1
Minowa, O.2
Kuno, J.3
Noda, T.4
Shibuya, M.5
-
66
-
-
0037040225
-
Flt-1-mediated down-regulation of endothelial cell proliferation through pertussis toxin-sensitive G proteins, beta gamma subunits, small GTPase CDC42, and partly by Rac-1
-
Zeng H, Zhao D, Mukhopadhyay D: Flt-1-mediated down-regulation of endothelial cell proliferation through pertussis toxin-sensitive G proteins, beta gamma subunits, small GTPase CDC42, and partly by Rac-1. J Biol Chem 277: 4003-4009, 2002
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4003-4009
-
-
Zeng, H.1
Zhao, D.2
Mukhopadhyay, D.3
-
67
-
-
0036076137
-
EGF receptor transactivation is obligatory for protein synthesis stimulation by G protein-coupled receptors
-
Voisin L, Foisy S, Giasson E, Lambert C, Moreau P, Meloche S: EGF receptor transactivation is obligatory for protein synthesis stimulation by G protein-coupled receptors. Am J Physiol Cell Physiol 283: C446-C455, 2002
-
(2002)
Am. J. Physiol. Cell Physiol.
, vol.283
-
-
Voisin, L.1
Foisy, S.2
Giasson, E.3
Lambert, C.4
Moreau, P.5
Meloche, S.6
-
68
-
-
0037738524
-
Transactivation of KDR/Flk-1 by the B2 receptor induces tube formation in human coronary endothelial cells
-
Miura S, Matsuo Y, Saku K: Transactivation of KDR/Flk-1 by the B2 receptor induces tube formation in human coronary endothelial cells. Hypertension 41: 1118-1123, 2003
-
(2003)
Hypertension
, vol.41
, pp. 1118-1123
-
-
Miura, S.1
Matsuo, Y.2
Saku, K.3
-
69
-
-
0038757626
-
Heterotrimeric G alpha q/G alpha 11 proteins function upstream of vascular endothelial growth factor (VEGF) receptor-2 (KDR) phosphorylation in vascular permeability factor/VEGF signaling
-
Zeng H, Zhao D, Yang S, Datta K, Mukhopadhyay D: Heterotrimeric G alpha q/G alpha 11 proteins function upstream of vascular endothelial growth factor (VEGF) receptor-2 (KDR) phosphorylation in vascular permeability factor/VEGF signaling. J Biol Chem 278: 20738-20745, 2003
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 20738-20745
-
-
Zeng, H.1
Zhao, D.2
Yang, S.3
Datta, K.4
Mukhopadhyay, D.5
-
70
-
-
0029867554
-
Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
-
Barleon B, Sozzani S, Zhou D, Weich HA, Mantovani A, Marme D: Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 87: 3336-3343, 1996
-
(1996)
Blood
, vol.87
, pp. 3336-3343
-
-
Barleon, B.1
Sozzani, S.2
Zhou, D.3
Weich, H.A.4
Mantovani, A.5
Marme, D.6
-
71
-
-
0030683639
-
Signal characteristics of G protein-transactivated EGF receptor
-
Daub H, Wallasch C, Lankenau A, Herrlich A, Ullrich A: Signal characteristics of G protein-transactivated EGF receptor. EMBO J 16: 7032-7044, 1997
-
(1997)
EMBO J.
, vol.16
, pp. 7032-7044
-
-
Daub, H.1
Wallasch, C.2
Lankenau, A.3
Herrlich, A.4
Ullrich, A.5
-
72
-
-
0037044854
-
Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS)
-
Tanimoto T, Jin ZG, Berk BC: Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS). J Biol Chem 277: 42997-43001, 2002
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42997-43001
-
-
Tanimoto, T.1
Jin, Z.G.2
Berk, B.C.3
-
73
-
-
0037127297
-
Rapid transactivation of the vascular endothelial growth factor receptor KDR/Flk-1 by the bradykinin B2 receptor contributes to endothelial nitric-oxide synthase activation in cardiac capillary endothelial cells
-
Thuringer D, Maulon L, Frelin C: Rapid transactivation of the vascular endothelial growth factor receptor KDR/Flk-1 by the bradykinin B2 receptor contributes to endothelial nitric-oxide synthase activation in cardiac capillary endothelial cells. J Biol Chem 277: 2028-2032, 2002
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2028-2032
-
-
Thuringer, D.1
Maulon, L.2
Frelin, C.3
-
74
-
-
0037068833
-
A D2 class dopamine receptor transactivates a receptor tyrosine kinase to inhibit NMDA receptor transmission
-
Kotecha SA, Oak JN, Jackson MF, Perez Y, Orser BA, Van Tol HH, MacDonald JF: A D2 class dopamine receptor transactivates a receptor tyrosine kinase to inhibit NMDA receptor transmission. Neuron 35: 1111-1122, 2002
-
(2002)
Neuron
, vol.35
, pp. 1111-1122
-
-
Kotecha, S.A.1
Oak, J.N.2
Jackson, M.F.3
Perez, Y.4
Orser, B.A.5
Van Tol, H.H.6
MacDonald, J.F.7
|