-
1
-
-
0017986411
-
Sterol content of foods of plant origin
-
Weihrauch JL & Gardner JM (1978) Sterol content of foods of plant origin. J Am Diet Assoc 73, 39-47.
-
(1978)
J Am Diet Assoc
, vol.73
, pp. 39-47
-
-
Weihrauch, J.L.1
Gardner, J.M.2
-
4
-
-
0032763577
-
Effects of dietary phy-tosterols on cholesterol metabolism and atherosclerosis: Clinical and experimental evidence
-
Moghadasian MH & Frohlich JJ (1999) Effects of dietary phy-tosterols on cholesterol metabolism and atherosclerosis: clinical and experimental evidence. Am J Med 107, 588-594.
-
(1999)
Am J Med
, vol.107
, pp. 588-594
-
-
Moghadasian, M.H.1
Frohlich, J.J.2
-
6
-
-
4344624966
-
Phytosterols and cholesterol metabolism
-
Ostlund RE Jr (2004) Phytosterols and cholesterol metabolism. Curr Opin Lipidol 15, 37-41.
-
(2004)
Curr Opin Lipidol
, vol.15
, pp. 37-41
-
-
Ostlund Jr., R.E.1
-
7
-
-
20444398521
-
Changes in intestinal and liver global gene expression in response to a phytosterol-enriched diet
-
Calpe-Berdiel L, Escola-Gil JC, Ribas V, et al. (2005) Changes in intestinal and liver global gene expression in response to a phytosterol-enriched diet. Atherosclerosis 181, 75-85.
-
(2005)
Atherosclerosis
, vol.181
, pp. 75-85
-
-
Calpe-Berdiel, L.1
Escola-Gil, J.C.2
Ribas, V.3
-
8
-
-
60949112151
-
New insights into the molecular actions of plant sterols and stanols in cholesterol metabolism
-
Calpe-Berdiel L, Escola-Gil JC & Blanco-Vaca F (2008) New insights into the molecular actions of plant sterols and stanols in cholesterol metabolism. Atherosclerosis 203, 18-31.
-
(2008)
Atherosclerosis
, vol.203
, pp. 18-31
-
-
Calpe-Berdiel, L.1
Escola-Gil, J.C.2
Blanco-Vaca, F.3
-
9
-
-
0035897696
-
Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP). Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
-
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
-
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (2001) Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA 285, 2486-2497.
-
(2001)
JAMA
, vol.285
, pp. 2486-2497
-
-
-
10
-
-
33750138814
-
Cholesterol absorption inhibitors as a therapeutic option for hypercholesterolaemia
-
Burnett JR & Huff MW (2006) Cholesterol absorption inhibitors as a therapeutic option for hypercholesterolaemia. Expert Opin Investig Drugs 15, 1337-1351.
-
(2006)
Expert Opin Investig Drugs
, vol.15
, pp. 1337-1351
-
-
Burnett, J.R.1
Huff, M.W.2
-
11
-
-
0035735021
-
Assessing the plasma pharmacokinetics, tissue distribution, excretion and effects on cholesterol pharmacokinetics of a novel hydrophilic compound, FM-VP4, following administration to rats
-
Wasan KM, Peteherych KD, Najafi S, et al. (2001) Assessing the plasma pharmacokinetics, tissue distribution, excretion and effects on cholesterol pharmacokinetics of a novel hydrophilic compound, FM-VP4, following administration to rats. J Pharm Pharm Sci 4, 207-216.
-
(2001)
J Pharm Pharm Sci
, vol.4
, pp. 207-216
-
-
Wasan, K.M.1
Peteherych, K.D.2
Najafi, S.3
-
12
-
-
0037309796
-
Influence of phytostanol phosphoryl ascorbate (FM-VP4) on insulin resistance, hyperglycemia, plasma lipid levels, and gastrointestinal absorption of exogenous cholesterol in Zucker (fa/fa) fatty and lean rats
-
Wasan KM, Zamfir C, Pritchard PH, et al. (2003) Influence of phytostanol phosphoryl ascorbate (FM-VP4) on insulin resistance, hyperglycemia, plasma lipid levels, and gastrointestinal absorption of exogenous cholesterol in Zucker (fa/fa) fatty and lean rats. J Pharm Sci 92, 281-288.
-
(2003)
J Pharm Sci
, vol.92
, pp. 281-288
-
-
Wasan, K.M.1
Zamfir, C.2
Pritchard, P.H.3
-
13
-
-
17244381308
-
Effects of a water-soluble phytostanol ester on plasma cholesterol levels and red blood cell fragility in hamsters
-
Ebine N, Jia X, Demonty I, et al. (2005) Effects of a water-soluble phytostanol ester on plasma cholesterol levels and red blood cell fragility in hamsters. Lipids 40, 175-180.
-
(2005)
Lipids
, vol.40
, pp. 175-180
-
-
Ebine, N.1
Jia, X.2
Demonty, I.3
-
14
-
-
0038413736
-
Disodium ascorbyl phytostanyl phosphate reduces plasma cholesterol concentrations and atherosclerotic lesion formation in apolipoprotein E-deficient mice
-
Lukic T, Wasan KM, Zamfir D, et al. (2003) Disodium ascorbyl phytostanyl phosphate reduces plasma cholesterol concentrations and atherosclerotic lesion formation in apolipoprotein E-deficient mice. Metabolism 52, 425-431.
-
(2003)
Metabolism
, vol.52
, pp. 425-431
-
-
Lukic, T.1
Wasan, K.M.2
Zamfir, D.3
-
15
-
-
0035155436
-
Effects of a novel hydrophilic phytostanol analog on plasma lipid concentrations in gerbils
-
Wasan KM, Najafi S, Peteherych KD, et al. (2001) Effects of a novel hydrophilic phytostanol analog on plasma lipid concentrations in gerbils. J Pharm Sci 90, 1795-1799.
-
(2001)
J Pharm Sci
, vol.90
, pp. 1795-1799
-
-
Wasan, K.M.1
Najafi, S.2
Peteherych, K.D.3
-
16
-
-
0035735017
-
Assessing plasma lipid levels, body weight, and hepatic and renal toxicity following chronic oral administration of a water soluble phytostanol compound, FM-VP4, to gerbils
-
Wasan KM, Najafi S, Wong J, et al. (2001) Assessing plasma lipid levels, body weight, and hepatic and renal toxicity following chronic oral administration of a water soluble phytostanol compound, FM-VP4, to gerbils. J Pharm Pharm Sci 4, 228-234.
-
(2001)
J Pharm Pharm Sci
, vol.4
, pp. 228-234
-
-
Wasan, K.M.1
Najafi, S.2
Wong, J.3
-
17
-
-
44449137540
-
Efficacy and safety of disodium ascorbyl phytostanol phosphates in men with moderate dyslipidemia
-
Vissers MN, Trip MD, Pritchard PH, et al. (2008) Efficacy and safety of disodium ascorbyl phytostanol phosphates in men with moderate dyslipidemia. Eur J Clin Pharmacol 64, 649-650.
-
(2008)
Eur J Clin Pharmacol
, vol.64
, pp. 649-650
-
-
Vissers, M.N.1
Trip, M.D.2
Pritchard, P.H.3
-
18
-
-
27444439374
-
Disodium ascorbyl phytostanyl phosphates (FM-VP4) reduces plasma cholesterol concentration, body weight and abdominal fat gain within a dietary-induced obese mouse model
-
Looije NA, Risovic V, Stewart DJ, et al. (2005) Disodium ascorbyl phytostanyl phosphates (FM-VP4) reduces plasma cholesterol concentration, body weight and abdominal fat gain within a dietary-induced obese mouse model. J Pharm Pharm Sci 8, 400-408.
-
(2005)
J Pharm Pharm Sci
, vol.8
, pp. 400-408
-
-
Looije, N.A.1
Risovic, V.2
Stewart, D.J.3
-
19
-
-
35649006931
-
Treatment with a cholesterol absorption inhibitor (FM-VP4) reduces body mass and adipose accumulation in developing and pre-obese mice
-
Thornton SJ, Warburton C, Wasan KM, et al. (2007) Treatment with a cholesterol absorption inhibitor (FM-VP4) reduces body mass and adipose accumulation in developing and pre-obese mice. Drug Dev Ind Pharm 33, 1058-1069.
-
(2007)
Drug Dev Ind Pharm
, vol.33
, pp. 1058-1069
-
-
Thornton, S.J.1
Warburton, C.2
Wasan, K.M.3
-
20
-
-
0024452728
-
Effects of sitosterol and sitostanol on micellar solubility of cholesterol
-
Ikeda I, Tanabe Y & Sugano M (1989) Effects of sitosterol and sitostanol on micellar solubility of cholesterol. J Nutr Sci Vitaminol (Tokyo) 35, 361-369.
-
(1989)
J Nutr Sci Vitaminol (Tokyo)
, vol.35
, pp. 361-369
-
-
Ikeda, I.1
Tanabe, Y.2
Sugano, M.3
-
21
-
-
0036482333
-
Effects of plant stanol esters on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase mRNA expression in mononuclear blood cells of healthy men and women
-
Plat J & Mensink RP (2002) Effects of plant stanol esters on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase mRNA expression in mononuclear blood cells of healthy men and women. FASEB J 16, 258-260.
-
(2002)
FASEB J
, vol.16
, pp. 258-260
-
-
Plat, J.1
Mensink, R.P.2
-
22
-
-
0035717056
-
Dietary plant stanol esters reduce VLDL cholesterol secretion and bile saturation in apolipoprotein E*3-Leiden transgenic mice
-
Volger OL, van der Boom H, de Wit EC, et al. (2001) Dietary plant stanol esters reduce VLDL cholesterol secretion and bile saturation in apolipoprotein E*3-Leiden transgenic mice. Arterioscler Thromb Vasc Biol 21, 1046-1052.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1046-1052
-
-
Volger, O.L.1
Van Der Boom, H.2
De Wit, E.C.3
-
23
-
-
0032920384
-
Dietary sitostanol reciprocally influences cholesterol absorption and biosynthesis in hamsters and rabbits
-
Ntanios FY & Jones PJ (1999) Dietary sitostanol reciprocally influences cholesterol absorption and biosynthesis in hamsters and rabbits. Atherosclerosis 143, 341-351.
-
(1999)
Atherosclerosis
, vol.143
, pp. 341-351
-
-
Ntanios, F.Y.1
Jones, P.J.2
-
24
-
-
46749113137
-
Long-term phytosterol treatment alters gene expression in the liver of apo E-deficient mice
-
Xu Z, Le K & Moghadasian MH (2007) Long-term phytosterol treatment alters gene expression in the liver of apo E-deficient mice. J Nutr Biochem 19, 545-554.
-
(2007)
J Nutr Biochem
, vol.19
, pp. 545-554
-
-
Xu Le Z, K.1
Moghadasian, M.H.2
-
25
-
-
0024269775
-
Competitive inhibition of bile acid synthesis by endogenous cholestanol and sitosterol in sitosterolemia with xanthomatosis. Effect on cholesterol 7 a-hydroxylase
-
Shefer S, Salen G, Nguyen L, et al. (1988) Competitive inhibition of bile acid synthesis by endogenous cholestanol and sitosterol in sitosterolemia with xanthomatosis. Effect on cholesterol 7 a-hydroxylase. J Clin Invest 82, 1833-1839.
-
(1988)
J Clin Invest
, vol.82
, pp. 1833-1839
-
-
Shefer, S.1
Salen, G.2
Nguyen, L.3
-
26
-
-
1242342236
-
Selective sterol accumulation in ABCG5/ABCG8-deficient mice
-
Yu L, von Bergmann K, Lutjohann D, et al. (2004) Selective sterol accumulation in ABCG5/ABCG8-deficient mice. J Lipid Res 45, 301-307.
-
(2004)
J Lipid Res
, vol.45
, pp. 301-307
-
-
Yu, L.1
Von Bergmann, K.2
Lutjohann, D.3
-
27
-
-
9644281617
-
Disruption of cholesterol homeostasis by plant sterols
-
Yang C, Yu L, Li W, et al. (2004) Disruption of cholesterol homeostasis by plant sterols. J Clin Invest 114, 813-822.
-
(2004)
J Clin Invest
, vol.114
, pp. 813-822
-
-
Yang, C.1
Yu, L.2
Li, W.3
-
28
-
-
0025132445
-
A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis
-
Nguyen LB, Shefer S, Salen G, et al. (1990) A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis. J Clin Invest 86, 923-931.
-
(1990)
J Clin Invest
, vol.86
, pp. 923-931
-
-
Nguyen, L.B.1
Shefer, S.2
Salen, G.3
-
29
-
-
0032941410
-
Serum sterols during stanol ester feeding in a mildly hypercholesterolemic population
-
Gylling H, Puska P, Vartiainen E, et al. (1999) Serum sterols during stanol ester feeding in a mildly hypercholesterolemic population. J Lipid Res 40, 593-600.
-
(1999)
J Lipid Res
, vol.40
, pp. 593-600
-
-
Gylling, H.1
Puska, P.2
Vartiainen, E.3
-
30
-
-
0034107086
-
Soy sterol esters and b-sitostanol ester as inhibitors of cholesterol absorption in human small bowel
-
Normen L, Dutta P, Lia A, et al. (2000) Soy sterol esters and b-sitostanol ester as inhibitors of cholesterol absorption in human small bowel. Am J Clin Nutr 71, 908-913.
-
(2000)
Am J Clin Nutr
, vol.71
, pp. 908-913
-
-
Normen, L.1
Dutta, P.2
Lia, A.3
-
31
-
-
0032751415
-
Safety evaluation of phytosterol esters. Part 4. Faecal concentrations of bile acids and neutral sterols in healthy normolipidaemic volunteers consuming a controlled diet either with or without a phytosterol ester-enriched margarine
-
Weststrate JA, Ayesh R, Bauer-Plank C, et al. (1999) Safety evaluation of phytosterol esters. Part 4. Faecal concentrations of bile acids and neutral sterols in healthy normolipidaemic volunteers consuming a controlled diet either with or without a phytosterol ester-enriched margarine. Food Chem Toxicol 37, 1063-1071.
-
(1999)
Food Chem Toxicol
, vol.37
, pp. 1063-1071
-
-
Weststrate, J.A.1
Ayesh, R.2
Bauer-Plank, C.3
-
32
-
-
33746660272
-
Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the ABCG5/8 transporter
-
Plosch T, Kruit JK, Bloks VW, et al. (2006) Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the ABCG5/8 transporter. J Nutr 136, 2135-2140.
-
(2006)
J Nutr
, vol.136
, pp. 2135-2140
-
-
Plosch, T.1
Kruit, J.K.2
Bloks, V.W.3
-
33
-
-
4744372778
-
Development and characterization of liposomal disodium ascorbyl phytostanyl phosphates (FM-VP4)
-
Ng AW, Lukic T, Pritchard PH, et al. (2004) Development and characterization of liposomal disodium ascorbyl phytostanyl phosphates (FM-VP4). Drug Dev Ind Pharm 30, 739-758.
-
(2004)
Drug Dev Ind Pharm
, vol.30
, pp. 739-758
-
-
Ng, A.W.1
Lukic, T.2
Pritchard, P.H.3
-
35
-
-
28444484300
-
Paradoxical exacerbation of combined hyperlipidemia in human apolipopro-tein A-II transgenic mice treated with fenofibrate
-
Ribas V, Palomer X, Roglans N, et al. (2005) Paradoxical exacerbation of combined hyperlipidemia in human apolipopro-tein A-II transgenic mice treated with fenofibrate. Biochim Biophys Acta 1737, 130-137.
-
(2005)
Biochim Biophys Acta
, vol.1737
, pp. 130-137
-
-
Ribas, V.1
Palomer, X.2
Roglans, N.3
-
36
-
-
0036845043
-
Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte
-
Repa JJ, Dietschy JM & Turley SD (2002) Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte. J Lipid Res 43, 1864-1874.
-
(2002)
J Lipid Res
, vol.43
, pp. 1864-1874
-
-
Repa, J.J.1
Dietschy, J.M.2
Turley, S.D.3
-
37
-
-
33645534069
-
Phytosterol-mediated inhibition of intestinal cholesterol absorption is independent of ATP-binding cassette transporter A1
-
Calpe-Berdiel L, Escola-Gil JC & Blanco-Vaca F (2006) Phytosterol-mediated inhibition of intestinal cholesterol absorption is independent of ATP-binding cassette transporter A1. Br J Nutr 95, 618-622.
-
(2006)
Br J Nutr
, vol.95
, pp. 618-622
-
-
Calpe-Berdiel, L.1
Escola-Gil, J.C.2
Blanco-Vaca, F.3
-
38
-
-
0036733630
-
Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
-
Yu L, Li-Hawkins J, Hammer RE, et al. (2002) Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J Clin Invest 110, 671-680.
-
(2002)
J Clin Invest
, vol.110
, pp. 671-680
-
-
Yu, L.1
Li-Hawkins, J.2
Hammer, R.E.3
-
39
-
-
0037072809
-
Increased hepatobili-ary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1
-
Plosch T, Kok T, Bloks VW, et al. (2002) Increased hepatobili-ary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1. J Biol Chem 277, 33870-33877.
-
(2002)
J Biol Chem
, vol.277
, pp. 33870-33877
-
-
Plosch, T.1
Kok, T.2
Bloks, V.W.3
-
40
-
-
3442902180
-
High-level expression of ABCG5 and ABCG8 attenuates diet-induced hypercholester-olemia and atherosclerosis in Ldlr 2/2 mice
-
Wilund KR, Yu L, Xu F, et al. (2004) High-level expression of ABCG5 and ABCG8 attenuates diet-induced hypercholester-olemia and atherosclerosis in Ldlr 2/2 mice. J Lipid Res 45, 1429-1436.
-
(2004)
J Lipid Res
, vol.45
, pp. 1429-1436
-
-
Wilund, K.R.1
Yu, L.2
Xu, F.3
-
41
-
-
0030960169
-
Over-expression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels
-
Kozarsky KF, Donahee MH, Rigotti A, et al. (1997) Over-expression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels. Nature 387, 414-417.
-
(1997)
Nature
, vol.387
, pp. 414-417
-
-
Kozarsky, K.F.1
Donahee, M.H.2
Rigotti, A.3
-
42
-
-
0034060299
-
Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse
-
Kozarsky KF, Donahee MH, Glick JM, et al. (2000) Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse. Arterioscler Thromb Vasc Biol 20, 721-727.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 721-727
-
-
Kozarsky, K.F.1
Donahee, M.H.2
Glick, J.M.3
-
43
-
-
33644865172
-
Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo
-
Naik SU, Wang X, Da Silva JS, et al. (2006) Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo. Circulation 113, 90-97.
-
(2006)
Circulation
, vol.113
, pp. 90-97
-
-
Naik, S.U.1
Wang, X.2
Da Silva, J.S.3
-
44
-
-
10044226295
-
Stanol esters decrease plasma cholesterol independently of intestinal ABC sterol transporters and Niemann-Pick C1-like 1 protein gene expression
-
Field FJ, Born E & Mathur SN (2004) Stanol esters decrease plasma cholesterol independently of intestinal ABC sterol transporters and Niemann-Pick C1-like 1 protein gene expression. J Lipid Res 45, 2252-2259.
-
(2004)
J Lipid Res
, vol.45
, pp. 2252-2259
-
-
Field, F.J.1
Born, E.2
Mathur, S.N.3
-
45
-
-
0036668184
-
Bile acid regulation of gene expression: Roles of nuclear hormone receptors
-
Chiang JY (2002) Bile acid regulation of gene expression: roles of nuclear hormone receptors. Endocr Rev 23, 443-463.
-
(2002)
Endocr Rev
, vol.23
, pp. 443-463
-
-
Chiang, J.Y.1
-
46
-
-
0037790917
-
The enzymes, regulation, and genetics of bile acid synthesis
-
Russell DW (2003) The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem 72, 137-174.
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 137-174
-
-
Russell, D.W.1
-
47
-
-
1242269851
-
Regulation of bile acid synthesis: Pathways, nuclear receptors, and mechanisms
-
Chiang JY (2004) Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms. J Hepatol 40, 539-551.
-
(2004)
J Hepatol
, vol.40
, pp. 539-551
-
-
Chiang, J.Y.1
-
48
-
-
33746605104
-
Benefit of farnesoid X receptor inhibition in obstructive cholestasis
-
Stedman C, Liddle C, Coulter S, et al. (2006) Benefit of farnesoid X receptor inhibition in obstructive cholestasis. Proc Natl Acad Sci USA 103, 11323-11328.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 11323-11328
-
-
Stedman, C.1
Liddle, C.2
Coulter, S.3
-
49
-
-
34548572892
-
Bile acid transporters: Structure, function, regulation and pathophysiological implications
-
Alrefai WA & Gill RK (2007) Bile acid transporters: structure, function, regulation and pathophysiological implications. Pharm Res 24, 1803-1823.
-
(2007)
Pharm Res
, vol.24
, pp. 1803-1823
-
-
Alrefai, W.A.1
Gill, R.K.2
-
50
-
-
34249747403
-
Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis
-
Teng S & Piquette-Miller M (2007) Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis. Br J Pharmacol 151, 367-376.
-
(2007)
Br J Pharmacol
, vol.151
, pp. 367-376
-
-
Teng, S.1
Piquette-Miller, M.2
|