-
1
-
-
0035735021
-
Assessing the plasma pharmacokinetics, tissue distribution, excretion and effects on cholesterol pharmacokinetics of a novel hydrophilic compound, FM-VP4, following administration to rats
-
Wasan KM, Peteherych KD, Najafi S, Zamfir C, Pritchard PH. 2001. Assessing the plasma pharmacokinetics, tissue distribution, excretion and effects on cholesterol pharmacokinetics of a novel hydrophilic compound, FM-VP4, following administration to rats. J Pharm Pharmaceut Sci 4:207-216.
-
(2001)
J Pharm Pharmaceut Sci
, vol.4
, pp. 207-216
-
-
Wasan, K.M.1
Peteherych, K.D.2
Najafi, S.3
Zamfir, C.4
Pritchard, P.H.5
-
2
-
-
0035163223
-
Assessing plasma pharmacokinetics of cholesterol following oral coadministration with a novel vegetable stanol mixture to fasting rats
-
Wasan KM, Holtorf L, Subramanian R, Cassidy SM, Pritchard PH, Stewart DJ, Novak E, Moghadasian MH. 2001. Assessing plasma pharmacokinetics of cholesterol following oral coadministration with a novel vegetable stanol mixture to fasting rats. J Pharm Sci 90:23-28.
-
(2001)
J Pharm Sci
, vol.90
, pp. 23-28
-
-
Wasan, K.M.1
Holtorf, L.2
Subramanian, R.3
Cassidy, S.M.4
Pritchard, P.H.5
Stewart, D.J.6
Novak, E.7
Moghadasian, M.H.8
-
3
-
-
0035735017
-
Assessing plasma lipid levels, body weight and hepatic and renal toxicity following chronic oral administration of a water soluble phytostanol compound, FM-VP4, to gerbils
-
Wasan KM, Najafi S, Wong J, Kwong M, Pritchard PH. 2001. Assessing plasma lipid levels, body weight and hepatic and renal toxicity following chronic oral administration of a water soluble phytostanol compound, FM-VP4, to gerbils. J Pharm Pharmaceut Sci 4:228-234.
-
(2001)
J Pharm Pharmaceut Sci
, vol.4
, pp. 228-234
-
-
Wasan, K.M.1
Najafi, S.2
Wong, J.3
Kwong, M.4
Pritchard, P.H.5
-
4
-
-
0035155436
-
Effects of a novel hydrophilic phytostanol analog on plasma lipid concentrations in gerbils
-
Wasan KM, Najafi S, Peteherych KD, Pritchard PH. 2001. Effects of a novel hydrophilic phytostanol analog on plasma lipid concentrations in gerbils. J Pharm Sci 90:1795-1799.
-
(2001)
J Pharm Sci
, vol.90
, pp. 1795-1799
-
-
Wasan, K.M.1
Najafi, S.2
Peteherych, K.D.3
Pritchard, P.H.4
-
5
-
-
0032763577
-
Effects of dietary phytosterols on cholesterol metabolism and atherosclerosis: Clinical and experimental evidence
-
Moghadasian MH, Frohlich JJ. 1999. Effects of dietary phytosterols on cholesterol metabolism and atherosclerosis: Clinical and experimental evidence. Am J Med 107:588-594.
-
(1999)
Am J Med
, vol.107
, pp. 588-594
-
-
Moghadasian, M.H.1
Frohlich, J.J.2
-
7
-
-
0027729980
-
Comparison of intestinal absorption of cholesterol with different plant sterols in man
-
Heinemann T, Axtmann G, von Bergmann K. 1993. Comparison of intestinal absorption of cholesterol with different plant sterols in man. Eur J Clin Invest 23:827-831.
-
(1993)
Eur J Clin Invest
, vol.23
, pp. 827-831
-
-
Heinemann, T.1
Axtmann, G.2
Von Bergmann, K.3
-
8
-
-
0024210833
-
Inhibition of cholesterol absorption in rats by plant sterols
-
Ikeda I, Tanaka K, Sugano M, Vahouny GV, Gallo LL. 1988. Inhibition of cholesterol absorption in rats by plant sterols. J Lipid Res 29:1573-1582.
-
(1988)
J Lipid Res
, vol.29
, pp. 1573-1582
-
-
Ikeda, I.1
Tanaka, K.2
Sugano, M.3
Vahouny, G.V.4
Gallo, L.L.5
-
9
-
-
0031870418
-
Improved glucose tolerance in Zucker Fatty rats by oral administration of the dipeptidyl peptidase IV inhibitor Isoleucine Thiazolidide
-
Pederson RA, White HA, Schlenzeg D, Pauly RP, McIntosh CHS, Demuth H-U. 1998. Improved glucose tolerance in Zucker Fatty rats by oral administration of the dipeptidyl peptidase IV inhibitor Isoleucine Thiazolidide. Diabetes 47:1253-1258.
-
(1998)
Diabetes
, vol.47
, pp. 1253-1258
-
-
Pederson, R.A.1
White, H.A.2
Schlenzeg, D.3
Pauly, R.P.4
McIntosh, C.H.S.5
Demuth, H.-U.6
-
10
-
-
0032821965
-
Insulin sensitivity indices obtained from oral glucose tolerance testing
-
Matsuda M, Defronzo RA. 1999. Insulin sensitivity indices obtained from oral glucose tolerance testing. Diabetes Care 22:1462-1467.
-
(1999)
Diabetes Care
, vol.22
, pp. 1462-1467
-
-
Matsuda, M.1
Defronzo, R.A.2
-
11
-
-
0026021161
-
Insulin resistance: A multifaceted syndrome response for NIDDM, obesity, hypertension, dyslipidemia and atherolsclerotic cardiovascular disease
-
De Fronzo RA, Ferrannini E. 1991. Insulin resistance: A multifaceted syndrome response for NIDDM, obesity, hypertension, dyslipidemia and atherolsclerotic cardiovascular disease. Diabetes Care 14:173-178.
-
(1991)
Diabetes Care
, vol.14
, pp. 173-178
-
-
De Fronzo, R.A.1
Ferrannini, E.2
-
12
-
-
0018833234
-
Effects of dietary changes on cellular insulin binding and in vivo insulin sensitivity
-
Beck-Nielsen H, Pedersen O, Sorensen NS. 1994. Effects of dietary changes on cellular insulin binding and in vivo insulin sensitivity. Metabolism 29:482-488.
-
(1994)
Metabolism
, vol.29
, pp. 482-488
-
-
Beck-Nielsen, H.1
Pedersen, O.2
Sorensen, N.S.3
-
13
-
-
0029855969
-
Comparison between permeability coefficients in rat and human jejunum
-
Fagerholm U, Johansson M, Lennernas H. 1996. Comparison between permeability coefficients in rat and human jejunum. Pharm Res 13:1336-1342.
-
(1996)
Pharm Res
, vol.13
, pp. 1336-1342
-
-
Fagerholm, U.1
Johansson, M.2
Lennernas, H.3
-
14
-
-
0029055473
-
Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals
-
Kararli TT. 1995. Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals. Biopharm Drug Dispos 16:351-380.
-
(1995)
Biopharm Drug Dispos
, vol.16
, pp. 351-380
-
-
Kararli, T.T.1
-
15
-
-
0029972886
-
Estimation of oral drug absorption in man based on intestine permeability in rats
-
Levet-Trafit B, Gruyer MS, Marjanovic M, Chou RC. 1996. Estimation of oral drug absorption in man based on intestine permeability in rats. Life Sci 58:PL359-PL363.
-
(1996)
Life Sci
, vol.58
-
-
Levet-Trafit, B.1
Gruyer, M.S.2
Marjanovic, M.3
Chou, R.C.4
-
16
-
-
0030346358
-
The validation of the intestinal permeability approach to predict oral fraction of dose absorbed in humans and rats
-
Soria I, Zimmerman CL. 1996. The validation of the intestinal permeability approach to predict oral fraction of dose absorbed in humans and rats. Biopharm Drug Dispos 17:817-818.
-
(1996)
Biopharm Drug Dispos
, vol.17
, pp. 817-818
-
-
Soria, I.1
Zimmerman, C.L.2
-
17
-
-
0031801066
-
Intestinal absorption and biliary secretion of cholesterol in rats with nephrotic syndrome
-
Pahl MV, Oveisi F, Khamiseh G, Vaziri ND. 1998. Intestinal absorption and biliary secretion of cholesterol in rats with nephrotic syndrome. Nephrol Dial Transplant 13:1446-1454.
-
(1998)
Nephrol Dial Transplant
, vol.13
, pp. 1446-1454
-
-
Pahl, M.V.1
Oveisi, F.2
Khamiseh, G.3
Vaziri, N.D.4
-
18
-
-
0021868137
-
Cholesterol metabolism in lean and obese Zucker rats: Effects of portacaval anastomosis
-
Bendjellit S, Mathe D, Castaing D, Bismuth H, Lutton C. 1985. Cholesterol metabolism in lean and obese Zucker rats: Effects of portacaval anastomosis. Int J Obes 9:1-9.
-
(1985)
Int J Obes
, vol.9
, pp. 1-9
-
-
Bendjellit, S.1
Mathe, D.2
Castaing, D.3
Bismuth, H.4
Lutton, C.5
-
19
-
-
0035376816
-
Diet enrichment with calcium and magnesium enhances the cholesterol-lowering effect of plant sterols in obese Zucker rats
-
Vaskonen T, Mervaala E, Seppanen-Laakso T, Karppanen H. 2001. Diet enrichment with calcium and magnesium enhances the cholesterol-lowering effect of plant sterols in obese Zucker rats. Nutr Metab Cardiovasc Dis 11:158-167.
-
(2001)
Nutr Metab Cardiovasc Dis
, vol.11
, pp. 158-167
-
-
Vaskonen, T.1
Mervaala, E.2
Seppanen-Laakso, T.3
Karppanen, H.4
-
21
-
-
0032239319
-
Assays of lecithin cholesterol acyltransferase (LCAT)
-
Ordovas JM, editor. Totowa, NJ: Humana Press Inc
-
Dobiasova M, Frohlich JJ. 1998. Assays of lecithin cholesterol acyltransferase (LCAT). In: Ordovas JM, editor. Methods in molecular biology, vol. 110: Lipoprotein protocols. Totowa, NJ: Humana Press Inc., pp 217-230.
-
(1998)
Methods in Molecular Biology, Vol. 110: Lipoprotein Protocols
, vol.110
, pp. 217-230
-
-
Dobiasova, M.1
Frohlich, J.J.2
-
23
-
-
0033528702
-
Proatherogenic and antiatherogenic effects of probucol and phytosterols in apoE-deficient mice: Possible mechanisms of action
-
Moghadasian MH, McManus BM, Godin DV, Rodrigues B, Frohlich JJ. 1999. Proatherogenic and antiatherogenic effects of probucol and phytosterols in apoE-deficient mice: Possible mechanisms of action. Circulation 99:1733-1799.
-
(1999)
Circulation
, vol.99
, pp. 1733-1799
-
-
Moghadasian, M.H.1
McManus, B.M.2
Godin, D.V.3
Rodrigues, B.4
Frohlich, J.J.5
-
24
-
-
0021248423
-
Serum lipoproteins and lecithin:cholesterol acyltransferase (LCAT) activity in hypercholesterolemic subjects given β-sitosterol
-
Weisweller P, Heinemann V, Schwandt P. 1984. Serum lipoproteins and lecithin:cholesterol acyltransferase (LCAT) activity in hypercholesterolemic subjects given β-sitosterol. Int J Clin Pharmacol 22:204-206.
-
(1984)
Int J Clin Pharmacol
, vol.22
, pp. 204-206
-
-
Weisweller, P.1
Heinemann, V.2
Schwandt, P.3
-
25
-
-
0027271933
-
Dietary olive oil reduces low-density lipoprotein uptake by macrophages and decreases the susceptibility of the lipoprotein to undergo lipid peroxidation
-
Aviram M, Eias K. 1993. Dietary olive oil reduces low-density lipoprotein uptake by macrophages and decreases the susceptibility of the lipoprotein to undergo lipid peroxidation. Ann Nutr Metab 37:75-84.
-
(1993)
Ann Nutr Metab
, vol.37
, pp. 75-84
-
-
Aviram, M.1
Eias, K.2
-
26
-
-
0026356722
-
Incorporation of liposomal phytosterols into human cells in culture: A potential in vitro model for investigating pathological effects of phytosterolemia
-
Bhadra S, Subbiah MT. 1991. Incorporation of liposomal phytosterols into human cells in culture: A potential in vitro model for investigating pathological effects of phytosterolemia. Biochem Med Met Biol 46:119-124.
-
(1991)
Biochem Med Met Biol
, vol.46
, pp. 119-124
-
-
Bhadra, S.1
Subbiah, M.T.2
-
27
-
-
34247554352
-
Influence of a novel phytostanol compound, FM-VP4, on pancreatic lipase activity and cholesterol accumulation within Caco-2 cells
-
Ramaswamy M, Peteherych KD, Li M, Yau E, Pritchard PH, Wasan KM. 2002. Influence of a novel phytostanol compound, FM-VP4, on pancreatic lipase activity and cholesterol accumulation within Caco-2 cells. J Pharm Pharmaceut Sci, 5:29-38.
-
(2002)
J Pharm Pharmaceut Sci
, vol.5
, pp. 29-38
-
-
Ramaswamy, M.1
Peteherych, K.D.2
Li, M.3
Yau, E.4
Pritchard, P.H.5
Wasan, K.M.6
-
28
-
-
12244262441
-
Effects of phytostanol phosphoryl ascorbate (FM-VP4) on cholesterol accumulation within rat intestinal cells
-
submitted
-
Wasan KM, Yau E, Boulanger KD, Ramaswamy M, Pritchard PH. 2002. Effects of phytostanol phosphoryl ascorbate (FM-VP4) on cholesterol accumulation within rat intestinal cells. Int J Pharm, submitted.
-
(2002)
Int J Pharm
-
-
Wasan, K.M.1
Yau, E.2
Boulanger, K.D.3
Ramaswamy, M.4
Pritchard, P.H.5
-
29
-
-
17744390348
-
Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters
-
Berge KE, Tian H, Graf GA, Yu L, Grishin NV, Schultz J, Kwiterovich P, Shan B, Barnes R, Hobbs HH. 2000. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 290:1771-1775.
-
(2000)
Science
, vol.290
, pp. 1771-1775
-
-
Berge, K.E.1
Tian, H.2
Graf, G.A.3
Yu, L.4
Grishin, N.V.5
Schultz, J.6
Kwiterovich, P.7
Shan, B.8
Barnes, R.9
Hobbs, H.H.10
-
30
-
-
0034284918
-
Regulation of absorption and ABC1-mediated efflux of cholesterol of RXR heterodimers
-
Repa JJ, Turley SD, Lobaccaro JMA, Medina J, Li L, Lustig K, Shan B, Heyman RA, Dietschy JM, Mangelsdorf DJ. 2000. Regulation of absorption and ABC1-mediated efflux of cholesterol of RXR Heterodimers. Science 289:1524-1529.
-
(2000)
Science
, vol.289
, pp. 1524-1529
-
-
Repa, J.J.1
Turley, S.D.2
Lobaccaro, J.M.A.3
Medina, J.4
Li, L.5
Lustig, K.6
Shan, B.7
Heyman, R.A.8
Dietschy, J.M.9
Mangelsdorf, D.J.10
-
31
-
-
0034529050
-
How cells handle cholesterol
-
Simons K, Ikonen E. 2000. How cells handle cholesterol. Science 290:1721-1725.
-
(2000)
Science
, vol.290
, pp. 1721-1725
-
-
Simons, K.1
Ikonen, E.2
|