Properties of drug-containing spherical pellets produced by a hot-melt extrusion and spheronization process

Journal of Microencapsulation

Volumn 20, Issue 5, 2003, Pages 613-625

  Young, Chris R ^a   Koleng, J J ^b   McGinity, J W ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b LLC   (United States)

Author keywords

Eudragit preparation 4135F; Hot melt extrusion; Spheronization; Theopylline; Wet mass extrusion

Indexed keywords

MACROGOL; MICROCRYSTALLINE CELLULOSE; SOLVENT; THEOPHYLLINE; WATER;

ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DISSOLUTION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PELLET; HEAT TREATMENT; MEASUREMENT; MICROENCAPSULATION; PARTICLE SIZE; PH; POROSITY; SCANNING ELECTRON MICROSCOPY; STRUCTURE ANALYSIS; TEMPERATURE; X RAY DIFFRACTION;

BIOCOMPATIBLE MATERIALS; CELLULOSE; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG COMPOUNDING; DRUG IMPLANTS; GELS; HEAT; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYMETHACRYLIC ACIDS; POROSITY; THEOPHYLLINE; X-RAY DIFFRACTION;

EID: 0041856220     PISSN: 02652048     EISSN: None     Source Type: Journal    
DOI: 10.1080/0265204031000148004     Document Type: Article

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