Investigation of the intestinal permeability and first-pass metabolism of drugs in cynomolgus monkeys using single-pass intestinal perfusion

Biological and Pharmaceutical Bulletin

Volumn 33, Issue 1, 2010, Pages 111-116

  Takahashi, Masayuki ^a   Washio, Takuo ^a   Suzuki, Norio ^a   Igeta, Katsuhiro ^a   Yamashita, Shinji ^b  

^a DAIICHI SANKYO CO   (Japan)

^b SETSUNAN UNIVERSITY   (Japan)

Author keywords

Bioavailability; Cynomolgus monkey; First pass metabolism; Intestinal absorption; Intestinal perfusion

Indexed keywords

1 AMINOBENZOTRIAZOLE; ATENOLOL; MIDAZOLAM; PARACETAMOL; PHENAZONE; PIROXICAM; PROPRANOLOL; VERAPAMIL;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG METABOLISM; EXPERIMENTAL MONKEY; FIRST PASS EFFECT; GASTROINTESTINAL TRACT; IN VIVO STUDY; INTESTINE MUCOSA PERMEABILITY; INTESTINE PERFUSION; MALE; NONHUMAN; PERIPHERAL VEIN; PORTAL VEIN; PORTAL VEIN BLOOD FLOW; SPECIES DIFFERENCE;

ADMINISTRATION, ORAL; ANIMALS; ANTIPYRINE; BIOLOGICAL AVAILABILITY; CYTOCHROME P-450 ENZYME SYSTEM; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; INTESTINES; MACACA FASCICULARIS; METABOLIC DETOXICATION, DRUG; PERFUSION; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; REFERENCE VALUES; TRIAZOLES;

EID: 75149184999     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.33.111     Document Type: Article

References (37)

1. Sakuda S., Akabane T., Teramura T., Xenobiotica, 36, 331-340 (2006).
2. Nishimura T., Amano N., Kubo Y., Ono M., Kato Y., Fujita H., Kimura Y., Tsuji A., Drug Metab. Dispos., 35, 1275-1284 (2007).
3. Takahashi M., Washio T., Suzuki N., Igeta K., Fujii Y., Hayashi M., Shirasaka Y., Yamashita S., Mol. Pharm., 5, 340-348 (2008).
4. Takahashi M., Washio T., Suzuki N., Igeta K., Yamashita S., J. Pharm. Sci., 98, 4343-4353 (2009).
5. Tamura S., Tokunaga Y., Ibuki R., Amidon G. L., Sezaki H., Yamashita, S., J. Pharmacol. Exp. Ther., 306, 310-316 (2003).
6. Mihara K., Matsumura M., Yoshioka E., Hanada K., Nakasa H., Ohmori S., Kitada M., Ogata H., Pharm. Res., 18, 1131-1137 (2001).
7. Kasim N. A., Whitehouse M., Ramachandran C., Bermejo M., Lennernäs H., Hussain A. S., Junginger H. E., Stavchansky S. A., Midha K. K., Shah V. P., Amidon, G. L., Mol. Pharm., 1, 85-96 (2004).
8. Balimane P. V., Chong S., Morrison R. A., J. Pharmacol. Toxicol. Methods, 44, 301-312 (2000).
9. Hidalgo I. J., Curr. Top. Med. Chem., 1, 385-401 (2001).
10. Hidalgo I. J., Raub T. J., Borchardt R. T., Gastroenterology, 96, 736-749 (1989).
11. Artursson P., Karlsson J., Biochem. Biophys. Res. Commun., 175, 880-885 (1991).
12. Yamashita S., Furubayashi T., Kataoka M.. Sakane T., Sezaki H., Tokuda H., Eur. J. Pharm. Sci., 10, 195-204 (2000).
13. Yee S., Pharm. Res., 14, 763-766 (1997).
14. Irvine J. D., Takahashi L., Lockhart K., Cheong J., Tolan J. W., Selick H. E., Grove J. R., J. Pharm. Sci., 88, 28-33 (1999).
15. Volpe D. A., J. Pharm. Sci., 97, 712-725 (2008).
16. Sugano K., Hamada H., Machida M., Ushio H., Saitoh K., Terada K., Int. J. Pharm., 228, 181-188 (2001).
17. Avdeef A., Bendels S., Faller B., Kansy M., Sugano K., Yamauchi Y., J. Pharm. Sci., 96, 2893-2909 (2007).
18. Fagerholm U., Johansson M., Linnernäs H., Pharm. Res., 13, 1336-1342 (1996).
19. Linnernäs H., J. Pharm. Sci., 87, 403-410 (1998).
20. Takamatsu N., Welage L. S., Idkaidek N. M., Liu D. Y., Lee P. I., Hayashi Y., Rhie J. K., Linnernäs H., Barnett J. L., Shah V. P., Lesko L., Amidon G. L., Pharm. Res., 14, 1127-1132 (1997).
21. Pang K. S., Cherry W. F. Ulm E. H., J. Pharmacol. Exp. Ther., 233, 788-795 (1985).
22. Iwao T., Inoue K., Hayashi Y., Yuasa H., Watanabe J., Drug Metab. Pharmacokinet., 17, 546-553 (2002).
23. Ungell A. L., Nylander S., Bergstrand S., Sjöberg Å., Linnernäs H., J. Pharm. Sci., 87, 360-366 (1998).
24. Paine M. F., Khalighi M., Fisher J. M., Shen D. D., Hunze K. L., Marsh C. L., Perkins J. D., Thummel K. E., J. Pharmacol. Exp. Ther., 283, 1552-1562 (1997).
25. Kararli T. T., Biopharm. Drug Dispos., 16, 351-380 (1995).
26. Chiou W. L., Buehler P. W., Pharm. Res., 19, 868-874 (2002).
27. Kroemer H. K., Gautier J. C., Beaune P., Henderson C., Wolf C. R., Eichelbaum M., Naunyn. Schmiedebergs Arch. Pharmacol., 348, 332-337 (1993).
28. Busse D., Cosme J., Beaune P., Kroemer H. K., Eichelbaum M., Naunyn. Schmiedebergs Arch. Pharmacol., 353, 116-121 (1995).
29. Sandström R., Karlsson A., Knutson L., Linnernäs H., Pharm. Res., 15, 856-862 (1998).
30. van de Kerkhof E. G., de Graaf I. A., Groothuis M. M., Curr. Drug Metab., 8, 658-675 (2007).
31. Komura H., Iwaki M., J. Pharm. Sci., 97, 1775-1800 (2008).
32. Yang J., Jamei M., Yeo K. R., Tucker G. T., Rostami-Hodjegan A., Curr. Drug Metab., 8, 676-684 (2007).
33. Kato M., Drug Metab. Pharmacokinet., 23, 87-94 (2008).
34. Davies B., Morris T., Pharm. Res., 10, 1093-1095 (1993).
35. Uhing M. R., Beno D. W., Jiyamapa-Serna V. A., Chen Y., Galinsky R. E., Hall S. D., Kimura R. E., Drug Metab. Dispos., 32, 1325-1330 (2004)
36. Reilly C. S., Merrell J., Wood A. J., Koshakji R. P., Wood M., Br. J. Anaesth., 60, 791-796 (1988).
37. Kanazu T., Yamaguchi Y., Okamura N., Baba T., Koike M., Xenobioteca, 34, 391-402 (2004).