Comparison of oral absorption and bioavailability of drugs between monkey and human

Pharmaceutical Research

Volumn 19, Issue 6, 2002, Pages 868-874

  Chiou, Win L ^a   Buehler, Paul W ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Drug absorption; Drug bioavailability; First pass metabolism; Monkey; Pharmacokinetics; Plasma clearance

Indexed keywords

BISOPROLOL; CAFFEINE; CARBAMAZEPINE; COUMARIN; CYCLOBENZAPRINE; DROLOXIFENE; FLUINDOSTATIN; FLUNISOLIDE; GUANABENZ; IRBESARTAN; LATANOPROST; LISURIDE; LIVER ENZYME; LORMETAZEPAM; METOPROLOL; MOXESTROL; NALTREXONE; NISOLDIPINE; PINDOLOL; PIRMENOL; PROPANOL; RECAINAM; RIFAPENTINE; ROLIPRAM; ROPINIROLE; UNINDEXED DRUG; VALACICLOVIR; VILOXAZINE; ZOLPIDEM; ZOMEPIRAC;

ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG FORMULATION; DRUG METABOLISM; ENZYME ACTIVITY; FIRST PASS EFFECT; MEDLINE; MONKEY; PRIORITY JOURNAL;

EID: 0036296060     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016169202830     Document Type: Article

References (33)

1. Pharmacokinetics and toxicity testing
2. Species similarities and differences in pharmacokinetics
3. Allometric pharmacokinetic scaling: Towards the prediction of human oral pharmacokinetics
4. Commentary: The rate and extent of oral bioavailability vs. the rate and extent of oral absorption: Classification and recommendation of terminology
5. Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats
6. Similarity in the linear and non-linear oral absorption of drugs between human and rat
7. Evaluation of dog as an animal model to study the fraction of oral dose absorbed for 43 drugs in humans
8. Comparison of human and rhesus monkey in vitro phase I and phase II hepatic drug metabolism activities
9. Comparison of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey
10. The absolute oral bioavailability of selected drugs
11. Design and optimization of dosage regimines: Pharmacokinetic data
12. Commentary: We may not measure the correct wall permeability coefficient of drugs: Alternative absorptive clearance concept
13. Commentary: New perspectives on the theory of of permeability and resistance in the study of drug absorption and transport
14. Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals
15. Prediction of oral absorption rate constant in human from in vivo rat data - Applications to interspecies scaling and first-dose in man study optimization
16. Allometric analysis of organ extraction ratios
17. The absorption of disopyramide in animals determined using a stable isotope co-administration technique
18. Metabolic disposition of 14C-venlafaxine in mouse, rat, dog, rhesus monkey and man
19. Pharmacokinetics of venlafaxine and O-desmethylvenlafaxine in laboratory animals
20. Species differences in oral bioavailability of methotrexate between rats and monkeys
21. Comparative pharmacokinetic profile of two imidazopyridine drugs: Zolpidem and alpidem
22. Pharmacokinetics of rolipram in the rhesus and cynomolgus monkeys, the rat and the rabbit. Studies on species differences
23. Biotransformation of the antidepressant D,L-rolipram. I. Isolation and identification of metabolites from rat, monkey, and human urine
24. Biotransformation of the antidepressant D,L-rolipram. II. Metabolite patterns in man, rat, rabbit, rhesus and cynomolgus monkey
25. Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys and humans
26. Species differences in the pharmacokinetics and metabolism of indinavir, a potent human immunodeficiency virus protease inhibitor
27. Oxidative metabolism of zolpidem by human liver cytochrome P450s
28. Comparative in vitro metabolism of indinavir in primates - A unique stereoselective hydroxylation in monkey
29. Pharmacokinetics of coumarin upon i.v. administration in man
30. Pharmacokinetics of coumarin and 7-hydroxycoumarin in the rhesus monkey after intravenous and peroral administration
31. Interspecies scaling of the pharmacokinetic parameters of coumarin among six different mammalian species