Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions

Reproduction

Volumn 139, Issue 1, 2010, Pages 85-97

  Forristal, Catherine E ^a,b   Wright, Kate L ^a,b   Hanley, Neil A ^a,b,c   Oreffo, Richard O C ^a,b   Houghton, Franchesca D ^a,b  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; HYPOXIA INDUCIBLE FACTOR 3ALPHA; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; OXYGEN; STAGE SPECIFIC EMBRYO ANTIGEN 1; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ARTICLE; CELL FUNCTION; CELL HYPOXIA; CELL NUCLEUS; CELL PROLIFERATION; CELL STRUCTURE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CYTOPLASM; EMBRYONIC STEM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; OXYGEN TENSION; PLURIPOTENCY; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; UPREGULATION;

ANTIGENS, CD15; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BIOLOGICAL MARKERS; CELL DEDIFFERENTIATION; CELL HYPOXIA; CELL LINE; CELL PROLIFERATION; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; INDUCED PLURIPOTENT STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; OXYGEN; PROTEIN TRANSPORT; RNA, MESSENGER; RNA, SMALL INTERFERING; SOXB1 TRANSCRIPTION FACTORS; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 75149117810     PISSN: 14701626     EISSN: 17417899     Source Type: Journal    
DOI: 10.1530/REP-09-0300     Document Type: Article

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