Differential modulation of mu-opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Gα subtype dependent

Journal of Neurochemistry

Volumn 112, Issue 4, 2010, Pages 1026-1034

  Talbot, Jeffery N ^a,b   Roman, David L ^a   Clark, Mary J ^a   Roof, Rebecca A ^a   Tesmer, John J G ^a,c   Neubig, Richard R ^a,c   Traynor, John R ^a,c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b OHIO NORTHERN UNIVERSITY   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Adenylyl cyclase; G proteins; Mu opioid; Permeabilization; Regulators of G protein signaling proteins

Indexed keywords

ADENYLATE CYCLASE; DIGITONIN; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FORSKOLIN; MU OPIATE RECEPTOR; REGULATOR OF G PROTEIN SIGNALING 7; REGULATOR OF G PROTEIN SIGNALING 8; RGS PROTEIN; RGS4 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GLIOMA CELL; NEUROMODULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RAT; SIGNAL TRANSDUCTION; STABLE EXPRESSION;

ADENYLATE CYCLASE; ANALGESICS, OPIOID; ANIMALS; CELL LINE, TUMOR; CYCLIC AMP; DIGITONIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; FLOW CYTOMETRY; FORSKOLIN; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); PROTEIN BINDING; RATS; RECEPTORS, OPIOID, MU; RGS PROTEINS; SIGNAL TRANSDUCTION;

EID: 75149115424     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06519.x     Document Type: Article

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