Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus

Hippocampus

Volumn 20, Issue 2, 2010, Pages 305-322

  Dahlhaus, Regina ^a   Hines, Rochelle M ^a   Eadie, Brennan D ^a,b   Kannangara, Timal S ^a,b   Hines, Dustin J ^a   Brown, Craig E ^a,b,c   Christie, Brian R ^a,b,c   El Hussefini, Alaa ^a,c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF VICTORIA   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Hippocampus; Learning and memory; Neuroligin; Synaptic plasticity; Synaptogenesis

Indexed keywords

ACTIN; CELL ADHESION MOLECULE; GEPHYRIN; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; GLUTAMATE RECEPTOR 3; NEUREXIN; NEUROLIGIN 1; NEUROLIGIN 2; NEUROLIGIN 3; POSTSYNAPTIC DENSITY PROTEIN 95; UNCLASSIFIED DRUG; VESICULAR GLUTAMATE TRANSPORTER; VESICULAR INHIBITORY AMINO ACID TRANSPORTER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ELECTRON MICROSCOPY; ELECTROPHYSIOLOGY; GOLGI COMPLEX; HIPPOCAMPUS; IN VIVO STUDY; LEARNING; LEARNING DISORDER; LONG TERM POTENTIATION; MEMORY CONSOLIDATION; MORPHOLOGY; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; SYNAPTOGENESIS; TRANSGENIC MOUSE;

ANIMALS; BRAIN; DENDRITIC SPINES; HIPPOCAMPUS; LEARNING DISORDERS; LONG-TERM POTENTIATION; MEMBRANE POTENTIALS; MEMORY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURAL CELL ADHESION MOLECULES; NEURAL INHIBITION; NEURONAL PLASTICITY; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 75149113269     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.20630     Document Type: Article

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