Neuronal activity regulates diffusion across the neck of dendritic spines

Science

Volumn 310, Issue 5749, 2005, Pages 866-869

  Bloodgood, Brenda L ^a   Sabatini, Bernardo L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; DIFFUSION; NATURAL SCIENCES;

DENDRITES; ELECTRICAL ISOLATION; NEURONS; SPINE;

NEUROLOGY;

BIOLOGY;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DENDRITE; DENDRITIC SPINE; DIFFUSION; MAMMAL; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; SYNAPSE;

ACTION POTENTIALS; ANIMALS; CYTOPLASM; DENDRITES; DENDRITIC SPINES; DIFFUSION; EXCITATORY POSTSYNAPTIC POTENTIALS; FLUORESCENCE; GLUTAMIC ACID; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; NEURONS; ORGAN CULTURE TECHNIQUES; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, GABA-A; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES; SYNAPTIC TRANSMISSION; TRANSFECTION; VISCOSITY;

ANIMALIA; MAMMALIA;

EID: 27644561757     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1114816     Document Type: Article

References (28)

1. R. C. Malenka, M. F. Bear, Neuron 44, S (2004).
2. R. J. Colbran, A. M. Brown, Curr. Opin. Neurobiol. 14, 318 (2004).
3. R. Malinow, H. Schulman, R. W. Tsien, Science 245, 862 (1989).
4. R. S. Zucker, Curr. Opin. Neurobiol. 9, 30S (1999).
5. K. Shen, M. N. Teruel, J. H. Connor, S. Shenolikar, T. Meyer, Nat. Neurosci. 3, 881 (2000).
6. S. Murase, E. Mosser, E. M. Schuman, Neuron 35, 91 (2002).
7. G. H. Patterson, J. Lippincott-Schwartz, Science 297, 1873 (2002).
8. J. N. Post, K. A. Lidke, B. Rieger, D. J. Arndt-Jovin, FEBS Lett. 579, 325 (2005).
9. K. Svoboda, D. W. Tank, W. Denk, Science 272, 716 (1996).
10. G. G. Turrigiano, K. R. Leslie, N. S. Desai, L. C. Rutherford, S. B. Nelson, Nature 391, 892 (1998).
11. T. C. Thiagarajan, E. S. Piedras-Renteria, R. W. Tsien, Neuron 36, 1103 (2002).
12. B. L. Bloodgood, B. L. Sabatini, data not shown.
13. R. Swaminathan, C. P. Hoang, A. S. Verkman, Blophys. J. 72, 1900 (1997).
14. E. N. Star, D. J. Kwiatkowski, V. N. Murthy, Nat. Neurosci. 5, 239 (2002).
15. M. Fischer, S. Kaech, U. Wagner, H. Brinkhaus, A. Matus, Nat. Neurosci. 3, 887 (2000).
16. F. Capani, M. E. Martone, T. J. Deerinck, M. H. Ellisman, J. Comp. Neurol. 435, 156 (2001).
17. Z. Li, K.-I. Okamoto, Y. Hayashi, M. Sheng, Cell 119, 873 (2004).
18. N. I. Kiskin, R. Chillingworth, J. A. McCray, D. Piston, D. Ogden, Eur. Biophys. J. 30, 588 (2002).
19. M. Canepari, L. Nelson, G. Papageorgiou, J. E. Corrie, D. Ogden, J. Neurosci. Methods 112, 29 (2001).
20. D. E. Feldman, Neuron 27, 45 (2000).
21. R. C. Froemke, M.-m. Poo, Y. Dan, Nature 434, 221 (2005).
22. G.-q. Bi, M.-m. Poo, J. Neurosci. 18, 10464 (1998).
23. S. M. Dudek, M. F. Bear, J. Neurosci. 13, 2910 (1993).
24. T. V. Bliss, T. Lomo, J. Physiol. 232, 331 (1973).
25. B. K. Andrasfalvy, J. C. Magee, J. Physiol. 559, 543 (2004).
26. C. Koch, A. Zador, J. Neurosci. 13, 413 (1993).
27. I. Segev, W. Rall, J. Neurophysiol. 60, 499 (1988).
28. We thank members of the Sabatini lab and B. Datta for helpful comments, suggestions, and critical reading of the manuscript. We thank J. Lippincott-Schwartz and J. Corrie and D. Ogden for the generous gifts of PAGFP and NPE-HPTS, respectively. This work was funded by the Searle Scholars Program, a McKnight Technological Innovations Award, the Hellman Family Faculty Fund, and the Whitaker Foundation. The authors declare that they have no competing financial interests.