Synthesis and anticonvulsant activity of new kojic acid derivatives

Arzneimittel-Forschung/Drug Research

Volumn 60, Issue 1, 2010, Pages 22-29

  Aytemir, Mutlu Dilsiz ^a   Septioǧlu, Ebubekir ^a   Çaliş, Ünsal ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Kojic acid derivatives, anticonvulsant activity, neurotoxicity; Mannich reaction

Indexed keywords

2 (4 ACETYLPIPERAZIN 1 YL METHYL) 3 HYDROXY 6 HYDROXYMETHYL 4H PYRAN 4 ONE; 2 [4 (2 CHLOROPHENYL)PIPERAZIN 1 YLMETHYL] 3 HYDROXY 6 HYDROXYMETHYL 4H PYRAN 4 ONE; 2 [4 (3 CHLOROPHENYL)PIPERAZIN 1 YLMETHYL] 3 HYDROXY 6 HYDROXYMETHYL 4H PYRAN 4 ONE; 2 [4 (4 CHLOROPHENYL)PIPERAZIN 1 YLMETHYL] 3 HYDROXY 6 HYDROXYMETHYL 4H PYRAN 4 ONE; 2 [4 (4 FLUOROPHENYL)PIPERAZIN 1 YL METHYL] 3 HYDROXY 6 HYDROXYMETHYL 4H PYRAN 4 ONE; 3 HYDROXY 6 HYDROXYMETHYL 2 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YLMETHYL] 4H PYRAN 4 ONE; 3 HYDROXY 6 HYDROXYMETHYL 2 [4 (3 TRIFLUOROMETHYLPHENYL)PIPERAZIN 1 YLMETHYL] 4H PYRAN 4 ONE; KOJIC ACID; TERT BUTYL 4 [[3 HYDROXY 6 (HYDROXYMETHYL) 4 OXO 4H PYRAN 2 YL]METHYL]PIPERAZINE 1 CARBOXYLATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SEIZURE;

EID: 74949142323     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296244     Document Type: Article

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