Synthesis, antimicrobial evaluation and QSAR study of some 3-hydroxypyridine-4-one and 3-hydroxypyran-4-one derivatives

European Journal of Medicinal Chemistry

Volumn 44, Issue 5, 2009, Pages 2145-2157

  Fassihi, Afshin ^a   Abedi, Daryoush ^a   Saghaie, Lotfollah ^a   Sabet, Razieh ^a   Fazeli, Hossein ^a   Bostaki, Ghasem ^a   Deilami, Omid ^a   Sadinpour, Hekmatollah ^a  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

3 Hydroxypyran 4 ones; 3 Hydroxypyridin 4 ones; Antimicrobial activity; QSAR

Indexed keywords

1 (3 HYDROXYPHENYL) 2 METHYL 3 HYDROXY PYRIDINE 4 ONE; 1 PHENYL 2 METHYL 3 HYDROXYPYRIDINE 4 ONE; 2 ETHYL 3 HYDROXY 5 N PIPERIDYLMETHYL PYRIDINE 4 ONE; 2 ETHYL 3 HYDROXY 5(N,N DIETHYL)AMINOMETHYL PYRIDINE 4 ONE; 2 ETHYL 3 HYDROXY 5(N,N DIMETHYL)AMINOMETHYL PYRIDINE 4 ONE; 2 METHYL 3 HYDROXY 5 N PIPERIDYLMETHYL PYRIDINE 4 ONE; 2 METHYL 3 HYDROXY 5(N,N DIMETHYL)AMINOMETHYL PYRIDINE 4 ONE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; PYRIDONE DERIVATIVE; PYRONE DERIVATIVE; REAGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; ASSAY; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; MULTIPLE LINEAR REGRESSION ANALYSIS; NONHUMAN; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; MICROBIAL SENSITIVITY TESTS; PYRIDONES; PYRONES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; STAPHYLOCOCCUS AUREUS;

EID: 62549089138     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.10.022     Document Type: Article

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