Identification of a functional nuclear export sequence in diacylglycerol kinase-ζ

Cell Cycle

Volumn 9, Issue 2, 2010, Pages 384-388

  Evangelisti, Camilla ^a   Gaboardi, Gian Carlo ^a   Billi, Anna Maria ^a   Ognibene, Andrea ^b   Goto, Kaoru ^c   Tazzari, Pier Luigi ^d   McCubrey, James A ^e   Martelli, Alberto M ^a,f  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^c YAMAGATA UNIVERSITY   (Japan)

^d UNIVERSITY OF BOLOGNA   (Italy)

^e EAST CAROLINA UNIVERSITY   (United States)

^f CNR   (Italy)

Author keywords

Cell cycle; CRM1; Diacylglycerol kinase; NES; Nucleus

Indexed keywords

DIACYLGLYCEROL KINASE; EXPORTIN 1; LEUCINE;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL LINE; CELL NUCLEUS; CYTOPLASM; MOUSE; MYOBLAST; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PROTEIN FUNCTION;

EID: 74949123708     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.2.10469     Document Type: Article

References (34)

1. Martelli AM, Bortul R, Tabellini G, Bareggi R, Manzoli L, Narducci P, et al. Diacylglycerol kinases in nuclear lipid-dependent signal transduction pathways. Cell Mol Life Sci 2002; 59:1129-37.
2. Hozumi Y, Ito T, Nakano T, Nakagawa T, Aoyagi M, Kondo H, et al. Nuclear localization of diacylglycerol kinase ζ in neurons. Eur J Neurosci 2003; 18:1448-57.
3. Goto K, Hozumi Y, Kondo H. Diacylglycerol, phosphatidic acid, and the converting enzyme, diacylglycerol kinase, in the nucleus. Biochim Biophys Acta 2006; 1761:535-41.
4. Topham MK, Bunting M, Zimmerman GA, McIntyre TM, Blackshear PJ, Prescott SM. Protein kinase C regulates the nuclear localization of diacylglycerol kinase-ζ. Nature 1998; 394:697-700.
5. Evangelisti C, Riccio M, Faenza I, Zini N, Hozumi Y, Goto K, et al. Subnuclear localization and differentiation-dependent increased expression of DGK-ζ in C2C12 mouse myoblasts. J Cell Physiol 2006; 209:370-8.
6. Evangelisti C, Tazzari PL, Riccio M, Fiume R, Hozumi Y, Fala F, et al. Nuclear diacylglycerol kinase-ζ is a negative regulator of cell cycle progression in C2C12 mouse myoblasts. FASEB J 2007; 21:3297-307.
7. Giacinti C, Giordano A. RB and cell cycle progression. Oncogene 2006; 25:5220-7.
8. Ji P, Zhu L. Using kinetic studies to uncover new Rb functions in inhibiting cell cycle progression. Cell Cycle 2005; 4:373-5.
9. Assoian RK, Yung Y. A reciprocal relationship between Rb and Skp2: implications for restriction point control, signal transduction to the cell cycle and cancer. Cell Cycle 2008; 7:24-7.
10. Kohrt DM, Crary JI, Gocheva V, Hinds PW, Grossel MJ. Distinct subcellular distribution of cyclin dependent kinase 6. Cell Cycle 2009; 8:2837-43.
11. Blain SW. Switching cyclin D-Cdk4 kinase activity on and off. Cell Cycle 2008; 7:892-8.
12. Mullany LK, White P, Hanse EA, Nelsen CJ, Goggin MM, Mullany JE, et al. Distinct proliferative and transcriptional effects of the D-type cyclins in vivo. Cell Cycle 2008; 7:2215-24.
13. Lim IK. TIS21 (/BTG2/PC3) as a link between ageing and cancer: cell cycle regulator and endogenous cell death molecule. J Cancer Res Clin Oncol 2006; 132:417-26.
14. Tamamori-Adachi M, Goto I, Yamada K, Kitajima S. Differential regulation of cyclin D1 and D2 in protecting against cardiomyocyte proliferation. Cell Cycle 2008; 7:3768-74.
15. 1 progression in untransformed human cells. Cell Cycle 2009; 8:125-36.
16. Evangelisti C, Astolfi A, Gaboardi GC, Tazzari P, Pession A, Goto K, et al. TIS21/BTG2/PC3 and cyclin D1 are key determinants of nuclear diacylglycerol kinase-ζ-dependent cell cycle arrest. Cell Signal 2009; 21:801-9.
17. Ali H, Nakano T, Saino-Saito S, Hozumi Y, Katagiri Y, Kamii H, et al. Selective translocation of diacylglycerol kinase ζ in hippocampal neurons under transient forebrain ischemia. Neurosci Lett 2004; 372:190-5.
18. Goto K, Kondo H. Heterogeneity of diacylglycerol kinase in terms of molecular structure, biochemical characteristics and gene expression localization in the brain. J Lipid Mediat Cell Signal 1996; 14:251-7.
19. Hamamoto T, Seto H, Beppu T. Leptomycins A and B, new antifungal antibiotics II. Structure elucidation. J Antibiot 1983; 36:646-50.
20. Yoshida M, Nishikawa M, Nishi K, Abe K, Horinouchi S, Beppu T. Effects of leptomycin B on the cell cycle of fibro-blasts and fission yeast cells. Exp Cell Res 1990; 187:150-6.
21. Kudo N, Wolff B, Sekimoto T, Schreiner EP, Yoneda Y, Yanagida M, et al. Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1. Exp Cell Res 1998; 242:540-7.
22. Nishi K, Yoshida M, Fujiwara D, Nishikawa M, Horinouchi S, Beppu T. Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression. J Biol Chem 1994; 269:6320-4.
23. Fornerod M, Ohno M, Yoshida M, Mattaj IW. CRM1 is an export receptor for leucine-rich nuclear export signals. Cell 1997; 90:1051-60.
24. Stade K, Ford CS, Guthrie C, Weis K. Exportin 1 (Crm1p) is an essential nuclear export factor. Cell 1997; 90:1041-50.
25. Ossareh-Nazari B, Bachelerie F, Dargemont C. Evidence for a role of CRM1 in signal-mediated nuclear protein export. Science 1997; 278:141-4.
26. Moroianu J. Nuclear import and export pathways. J Cell Biochem 1999; 33:76-83.
27. Kutay U, Guttinger S. Leucine-rich nuclear-export signals: born to be weak. Trends Cell Biol 2005; 15:121-4.
28. Fornerod M, Ohno M. Exportin-mediated nuclear export of proteins and ribonucleoproteins. Results Probl Cell Differ 2002; 35:67-91.
29. Ivanova IA, Vespa A, Dagnino L. A novel mechanism of E2F1 regulation via nucleocytoplasmic shuttling: determinants of nuclear import and export. Cell Cycle 2007; 6:2186-95.
30. Slattery SD, Mancini MA, Brinkley BR, Hall RM. Aurora-C kinase supports mitotic progression in the absence of Aurora-B. Cell Cycle 2009; 8:2984-94.
31. Stubbert LJ, Spronck JC, Hamill JD, McKay BC. Ultraviolet light induces the sustained unscheduled expression of cyclin E in the absence of functional p53. Cell Cycle 2009; 8:2995-3002.
32. Lindsay CR, Giovinazzi S, Ishov AM. Daxx is a pre-dominately nuclear protein that does not translocate to the cytoplasm in response to cell stress. Cell Cycle 2009; 8:1544-51.
33. Gaundar SS, Bradstock KF, Bendall LJ. p38MAPK inhibitors attenuate cytokine production by bone marrow stromal cells and reduce stroma-mediated proliferation of acute lymphoblastic leukemia cells. Cell Cycle 2009; 8:2975-83.
34. Cruet-Hennequart S, Villalan S, Kaczmarczyk A, O'Meara E, Sokol AM, Carty MP. Characterization of the effects of cisplatin and carboplatin on cell cycle progression and DNA damage response activation in DNA polymeraseη-deficient human cells. Cell Cycle 2009; 8:3039-50.