Jab1 regulates levels of endothelin type A and B receptors by promoting ubiquitination and degradation

Biochemical and Biophysical Research Communications

Volumn 391, Issue 4, 2010, Pages 1616-1622

  Nishimoto, Arata ^a   Lu, Lingyun ^a   Hayashi, Misato ^a   Nishiya, Tadashi ^a   Horinouchi, Takahiro ^a   Miwa, Soichi ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

G protein coupled receptor (GPCR); GPCR interacting protein (GIP); Jun activation domain binding protein 1 (Jab1); Protein degradation; Ubiquitination; Yeast two hybrid screening

Indexed keywords

BINDING PROTEIN; COMPLEMENTARY DNA; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; GLUTATHIONE TRANSFERASE; JUN ACTIVATION DOMAIN BINDING PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYC PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CELL SURFACE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA LIBRARY; EMBRYO; ENZYME ASSAY; ENZYME PHOSPHORYLATION; HEART; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; REGULATORY MECHANISM; TWO HYBRID SYSTEM; UBIQUITINATION; YEAST;

CELL LINE; GENE KNOCKDOWN TECHNIQUES; GENE LIBRARY; HUMANS; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MYOCARDIUM; PEPTIDE HYDROLASES; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITINATION;

EID: 74449092397     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.12.087     Document Type: Article

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