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Volumn 3, Issue 10, 2004, Pages 1281-1288

BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 CHLORO 4 IODOANILINO) N CYCLOPROPYLMETHOXY 3,4 DIFLUOROBENZAMIDE; BH3 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN ANTIBODY; SERINE;

EID: 7444233268     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (40)

References (42)
  • 2
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • Frisch SM, Francis H. Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 1994;124:619-26.
    • (1994) J. Cell Biol. , vol.124 , pp. 619-626
    • Frisch, S.M.1    Francis, H.2
  • 4
    • 0012366019 scopus 로고    scopus 로고
    • Mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors restore anoikis sensitivity in human breast cancer cell lines with a constitutively activated extracellular-regulated kinase (ERK) pathway
    • Fukazawa H, Noguchi K, Murakami Y, Uehara Y. Mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors restore anoikis sensitivity in human breast cancer cell lines with a constitutively activated extracellular-regulated kinase (ERK) pathway. Mol Cancer Ther 2002;1:303-9.
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 303-309
    • Fukazawa, H.1    Noguchi, K.2    Murakami, Y.3    Uehara, Y.4
  • 5
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • Cory S, Adams JM. The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2002;2:647-56.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 6
    • 0142117313 scopus 로고    scopus 로고
    • The Bcl-2 family: Roles in cell survival and oncogenesis
    • Cory S, Huang DC, Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 2003;22:8590-607.
    • (2003) Oncogene , vol.22 , pp. 8590-8607
    • Cory, S.1    Huang, D.C.2    Adams, J.M.3
  • 7
    • 0033104996 scopus 로고    scopus 로고
    • The proapoptotic activity of the Bcl-2 family member Bif: Is regulated by interaction with the dynein motor complex
    • Puthalakath H, Huang DC, O'Reilly LA, King SM, Strasser A. The proapoptotic activity of the Bcl-2 family member Bif: is regulated by interaction with the dynein motor complex. Mol Cell 1999;3:287-96.
    • (1999) Mol. Cell , vol.3 , pp. 287-296
    • Puthalakath, H.1    Huang, D.C.2    O'Reilly, L.A.3    King, S.M.4    Strasser, A.5
  • 8
    • 0035823238 scopus 로고    scopus 로고
    • Bmf: A proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
    • Puthalakath H, Villunger A, O'Reilly LA, et al. Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science 2001;293:1829-32.
    • (2001) Science , vol.293 , pp. 1829-1832
    • Puthalakath, H.1    Villunger, A.2    O'Reilly, L.A.3
  • 9
    • 0032518787 scopus 로고    scopus 로고
    • Bim: A novel member of the Bcl-2 family that promotes apoptosis
    • O'Connor L, Strasser A, O'Reilly LA, et al. Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J 1998;17:384-95.
    • (1998) EMBO J. , vol.17 , pp. 384-395
    • O'Connor, L.1    Strasser, A.2    O'Reilly, L.A.3
  • 10
    • 0032161337 scopus 로고    scopus 로고
    • BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members
    • Hsu SY, Lin P, Hsueh AJ. BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members. Mol Endocrinol 1998;12:1432-40.
    • (1998) Mol. Endocrinol. , vol.12 , pp. 1432-1440
    • Hsu, S.Y.1    Lin, P.2    Hsueh, A.J.3
  • 11
    • 0035977077 scopus 로고    scopus 로고
    • Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family
    • U M, Miyashita T, Shikama Y, Tadokoro K, Yamada M. Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family. FEBS Lett 2001;509:135-41.
    • (2001) FEBS Lett. , vol.509 , pp. 135-141
    • U, M.1    Miyashita, T.2    Shikama, Y.3    Tadokoro, K.4    Yamada, M.5
  • 12
    • 0036091728 scopus 로고    scopus 로고
    • Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis
    • Marani M, Tenev T, Hancock D, Downward J, Lemoine NR. Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis. Mol Cell Biol 2002;22:3577-89.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 3577-3589
    • Marani, M.1    Tenev, T.2    Hancock, D.3    Downward, J.4    Lemoine, N.R.5
  • 13
    • 0037092570 scopus 로고    scopus 로고
    • Identification and characterization of Bimγ, a novel proapoptotic BH3-only splice variant of Bim
    • Liu JW, Chandra D, Tang SH, Chopra D, Tang DG. Identification and characterization of Bimγ, a novel proapoptotic BH3-only splice variant of Bim. Cancer Res 2002;62:2976-81.
    • (2002) Cancer Res. , vol.62 , pp. 2976-2981
    • Liu, J.W.1    Chandra, D.2    Tang, S.H.3    Chopra, D.4    Tang, D.G.5
  • 14
    • 0032984348 scopus 로고    scopus 로고
    • Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
    • Sebolt-Leopold JS, Dudley DT, Herrera R, et al. Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nat Med 1999;5:810-6.
    • (1999) Nat. Med. , vol.5 , pp. 810-816
    • Sebolt-Leopold, J.S.1    Dudley, D.T.2    Herrera, R.3
  • 15
    • 0035135349 scopus 로고    scopus 로고
    • Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors
    • Shinjyo T, Kuribara R, Inukai T, et al. Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors. Mol Cell Biol 2001;21: 854-64.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 854-864
    • Shinjyo, T.1    Kuribara, R.2    Inukai, T.3
  • 16
    • 0034682783 scopus 로고    scopus 로고
    • Hypoxia inducible factor-α binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
    • Cockman ME, Masson N, Mole DR, et al. Hypoxia inducible factor-α binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein. J Biol Chem 2000;275:25733-41.
    • (2000) J. Biol. Chem. , vol.275 , pp. 25733-25741
    • Cockman, M.E.1    Masson, N.2    Mole, D.R.3
  • 17
    • 0029078999 scopus 로고
    • A microplate assay for quantitation of anchorage-independent growth of transformed cells
    • Fukazawa H, Mizuno S, Uehara Y. A microplate assay for quantitation of anchorage-independent growth of transformed cells. Anal Biochem 1995;228:83-90.
    • (1995) Anal. Biochem. , vol.228 , pp. 83-90
    • Fukazawa, H.1    Mizuno, S.2    Uehara, Y.3
  • 18
    • 0034655220 scopus 로고    scopus 로고
    • U0126 reverses Ki-ras-mediated transformation by blocking both mitogen-activated protein kinase and p70 S6 kinase pathways
    • Fukazawa H, Uehara Y. U0126 reverses Ki-ras-mediated transformation by blocking both mitogen-activated protein kinase and p70 S6 kinase pathways. Cancer Res 2000;60:2104-7.
    • (2000) Cancer Res. , vol.60 , pp. 2104-2107
    • Fukazawa, H.1    Uehara, Y.2
  • 19
    • 0034609737 scopus 로고    scopus 로고
    • Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
    • Dijkers PF, Madame RH, Lammers JW, Koenderman L, Coffer PJ. Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr Biol 2000;10:1201-4.
    • (2000) Curr. Biol. , vol.10 , pp. 1201-1204
    • Dijkers, P.F.1    Madame, R.H.2    Lammers, J.W.3    Koenderman, L.4    Coffer, P.J.5
  • 20
    • 0037017396 scopus 로고    scopus 로고
    • FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: Protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity
    • Dijkers PF, Birkenkamp KU, Lam EW, et al. FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity. J Cell Biol 2002;156:531-42.
    • (2002) J. Cell Biol. , vol.156 , pp. 531-542
    • Dijkers, P.F.1    Birkenkamp, K.U.2    Lam, E.W.3
  • 21
    • 0037094096 scopus 로고    scopus 로고
    • The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2
    • Stahl M, Dijkers PF, Kops GJ, et al. The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2. J Immunol 2002;168:5024-31.
    • (2002) J. Immunol. , vol.168 , pp. 5024-5031
    • Stahl, M.1    Dijkers, P.F.2    Kops, G.J.3
  • 22
    • 0035851204 scopus 로고    scopus 로고
    • BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons
    • Harris CA, Johnson EM Jr. BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons. J Biol Chem 2001;276:37754-60.
    • (2001) J. Biol. Chem. , vol.276 , pp. 37754-37760
    • Harris, C.A.1    Johnson Jr., E.M.2
  • 23
    • 0035053624 scopus 로고    scopus 로고
    • Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis
    • Putcha GV, Moulder KL, Golden JP, et al. Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron 2001;29:615-28.
    • (2001) Neuron , vol.29 , pp. 615-628
    • Putcha, G.V.1    Moulder, K.L.2    Golden, J.P.3
  • 24
    • 0035049449 scopus 로고    scopus 로고
    • Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release
    • Whitfield J, Neame SJ, Paquet L, Bernard O, Ham J. Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Neuron 2001;29:629-43.
    • (2001) Neuron , vol.29 , pp. 629-643
    • Whitfield, J.1    Neame, S.J.2    Paquet, L.3    Bernard, O.4    Ham, J.5
  • 25
    • 0042477712 scopus 로고    scopus 로고
    • FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
    • Gilley J, Coffer PJ, Ham J. FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J Cell Biol 2003;162:613-22.
    • (2003) J. Cell Biol. , vol.162 , pp. 613-622
    • Gilley, J.1    Coffer, P.J.2    Ham, J.3
  • 26
    • 10744230034 scopus 로고    scopus 로고
    • FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines
    • Sunters A, Fernandez de Mattos S, Stahl M, et al. FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines. J Biol Chem 2003;278:49795-805.
    • (2003) J. Biol. Chem. , vol.278 , pp. 49795-49805
    • Sunters, A.1    Fernandez de Mattos, S.2    Stahl, M.3
  • 27
    • 0042696985 scopus 로고    scopus 로고
    • Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis
    • Reginato MJ, Mills KR, Paulus JK, et al. Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nat Cell Biol 2003;5:733-40.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 733-740
    • Reginato, M.J.1    Mills, K.R.2    Paulus, J.K.3
  • 29
    • 0037422172 scopus 로고    scopus 로고
    • Activation of ERK 1/2 by δRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways
    • Weston CR, Balmanno K, Chalmers C, et al. Activation of ERK 1/2 by δRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways. Oncogene 2003;22:1281-93.
    • (2003) Oncogene , vol.22 , pp. 1281-1293
    • Weston, C.R.1    Balmanno, K.2    Chalmers, C.3
  • 30
    • 0037147122 scopus 로고    scopus 로고
    • Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation
    • Biswas SC, Greene LA. Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation. J Biol Chem 2002;277:49511-6.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49511-49516
    • Biswas, S.C.1    Greene, L.A.2
  • 31
    • 0037418238 scopus 로고    scopus 로고
    • JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
    • Lei K, Davis RJ. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc Natl Acad Sci U S A 2003;100:2432-7.
    • (2003) Proc. Natl. Acad. Sci. U S A , vol.100 , pp. 2432-2437
    • Lei, K.1    Davis, R.J.2
  • 32
    • 0242521470 scopus 로고    scopus 로고
    • Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function
    • Luciano F, Jacquel A, Colosetti P, et al. Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. Oncogene 2003;22: 6785-93.
    • (2003) Oncogene , vol.22 , pp. 6785-6793
    • Luciano, F.1    Jacquel, A.2    Colosetti, P.3
  • 33
    • 1542275411 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases 1/2 are serum-stimulated "BimEL-kinases" that bind to the BH3-only protein BimEL causing its phosphorylation and turnover
    • Ley R, Ewings KE, Hadfield K, Howes E, Balmanno K, Cook SJ. Extracellular signal-regulated kinases 1/2 are serum-stimulated "BimEL-kinases" that bind to the BH3-only protein BimEL causing its phosphorylation and turnover. J Biol Chem 2004;279:8837-47.
    • (2004) J. Biol. Chem. , vol.279 , pp. 8837-8847
    • Ley, R.1    Ewings, K.E.2    Hadfield, K.3    Howes, E.4    Balmanno, K.5    Cook, S.J.6
  • 34
    • 0033590636 scopus 로고    scopus 로고
    • Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors
    • Hoshino R, Chatani Y, Yamori T, et al. Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors. Oncogene 1999;18:813-22.
    • (1999) Oncogene , vol.18 , pp. 813-822
    • Hoshino, R.1    Chatani, Y.2    Yamori, T.3
  • 35
    • 0037860975 scopus 로고    scopus 로고
    • JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
    • Putcha GV, Le S, Frank S, et al. JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron 2003;38:899-914.
    • (2003) Neuron , vol.38 , pp. 899-914
    • Putcha, G.V.1    Le, S.2    Frank, S.3
  • 36
    • 0038482050 scopus 로고    scopus 로고
    • Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim
    • Ley R, Balmanno K, Hadfield K, Weston C, Cook SJ. Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J Biol Chem 2003; 278:18811-6.
    • (2003) J. Biol. Chem. , vol.278 , pp. 18811-18816
    • Ley, R.1    Balmanno, K.2    Hadfield, K.3    Weston, C.4    Cook, S.J.5
  • 37
    • 0038056194 scopus 로고    scopus 로고
    • Phosphorylation of the pro-apoptotic protein Bim in lymphocytes is associated with protection from apoptosis
    • Seward RJ, von Haller PD, Aebersold R, Huber BT. Phosphorylation of the pro-apoptotic protein Bim in lymphocytes is associated with protection from apoptosis. Mol Immunol 2003;39:983-93.
    • (2003) Mol. Immunol. , vol.39 , pp. 983-993
    • Seward, R.J.1    von Haller, P.D.2    Aebersold, R.3    Huber, B.T.4
  • 38
    • 0442279251 scopus 로고    scopus 로고
    • B cell receptor-mediated apoptosis of human lymphocytes is associated with a new regulatory pathway of birn isoform expression
    • Mouhamad S, Besnault L, Auffredou MT, et al. B cell receptor-mediated apoptosis of human lymphocytes is associated with a new regulatory pathway of birn isoform expression. J Immunol 2004;172:2084-91.
    • (2004) J. Immunol. , vol.172 , pp. 2084-2091
    • Mouhamad, S.1    Besnault, L.2    Auffredou, M.T.3
  • 39
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet P, Metcalf D, Huang DC, et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999;286:1735-8.
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1    Metcalf, D.2    Huang, D.C.3
  • 40
    • 0034671527 scopus 로고    scopus 로고
    • MEK inhibition enhances paclitaxel-induced tumor apoptosis
    • MacKeigan JP, Collins TS, Ting JP. MEK inhibition enhances paclitaxel-induced tumor apoptosis. J Biol Chem 2000;275:38953-6.
    • (2000) J. Biol. Chem. , vol.275 , pp. 38953-38956
    • MacKeigan, J.P.1    Collins, T.S.2    Ting, J.P.3
  • 41
    • 0034920013 scopus 로고    scopus 로고
    • Selective potentiation of paclitaxel (taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell lines
    • McDaid HM, Horwitz SB. Selective potentiation of paclitaxel (taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell lines. Mol Pharmacol 2001;60:290-301.
    • (2001) Mol. Pharmacol. , vol.60 , pp. 290-301
    • McDaid, H.M.1    Horwitz, S.B.2
  • 42
    • 0035425774 scopus 로고    scopus 로고
    • The role of ERK 1/2 and p38 MAP-kinase pathways in taxol-induced apoptosis in human ovarian carcinoma cells
    • Seidman R, Gitelman I, Sagi O, Horwitz SB, Wolfson M. The role of ERK 1/2 and p38 MAP-kinase pathways in taxol-induced apoptosis in human ovarian carcinoma cells. Exp Cell Res 2001;268:84-92.
    • (2001) Exp. Cell Res. , vol.268 , pp. 84-92
    • Seidman, R.1    Gitelman, I.2    Sagi, O.3    Horwitz, S.B.4    Wolfson, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.