Activation of MTK1/MEKK4 induces cardiomyocyte death and heart failure

Journal of Molecular and Cellular Cardiology

Volumn 48, Issue 2, 2010, Pages 302-309

  Mizote, Isamu ^a   Yamaguchi, Osamu ^a   Hikoso, Shungo ^a   Takeda, Toshihiro ^a   Taneike, Manabu ^a   Oka, Takafumi ^a   Tamai, Takahito ^a   Oyabu, Jota ^a   Matsumura, Yasushi ^a   Nishida, Kazuhiko ^a   Komuro, Issei ^a   Hori, Masatsugu ^a   Otsu, Kinya ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Heart failure; JNK; MTK1; p38

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADENOVIRUS VECTOR; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; MUTANT PROTEIN; PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ISOLATION; CELL SURVIVAL; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENZYME ACTIVATION; ENZYME DEGRADATION; GENE OVEREXPRESSION; HEART FAILURE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE CELL; HEART PROTECTION; HEART STRESS; IN VITRO STUDY; IN VIVO STUDY; LUNG WEIGHT; MALE; MORTALITY; NEWBORN; NICK END LABELING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; RAT; SYSTOLIC BLOOD PRESSURE; TRANSGENIC MOUSE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; CELL DEATH; ENZYME ACTIVATION; HEART FAILURE; HYDROGEN PEROXIDE; MAP KINASE KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MICE; MICE, TRANSGENIC; MUTANT PROTEINS; MYOCARDIUM; MYOCYTES, CARDIAC; ORGAN SPECIFICITY; RATS;

MUS; MUS MUSCULUS; RATTUS;

EID: 74149085805     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.10.010     Document Type: Article

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