Ca2+-sensitive tyrosine kinase Pyk2/CAK β-dependent signaling is essential for G-protein-coupled receptor agonist-induced hypertrophy

Journal of Molecular and Cellular Cardiology

Volumn 36, Issue 6, 2004, Pages 799-807

  Hirotani, Shinichi ^a   Higuchi, Yoshiharu ^a   Nishida, Kazuhiko ^a   Nakayama, Hiroyuki ^a   Yamaguchi, Osamu ^a   Hikoso, Shungo ^a   Takeda, Toshihiro ^a   Kashiwase, Kazunori ^a   Watanabe, Tetsuya ^a   Asahi, Michio ^a   Taniike, Masayuki ^a   Tsujimoto, Ikuko ^b   Matsumura, Yasushi ^a   Sasaki, Terukatsu ^c   Hori, Masatsugu ^a   Otsu, Kinya ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Ca2+; Cardiomyocyte hypertrophy; GPCR; Pyk2; RAC1

Indexed keywords

ADENOVIRUS VECTOR; ATRIAL NATRIURETIC FACTOR; CALCIUM; ENDOTHELIN 1; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FOCAL ADHESION KINASE 2; G PROTEIN COUPLED RECEPTOR; IONOMYCIN; LEUCINE; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; TRITIUM; TYROSINE;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; EXPERIMENTAL INFECTION; HEART HYPERTROPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS REGULATION; RAT; RECEPTOR INTRINSIC ACTIVITY; SARCOMERE; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; CARDIOMEGALY; CELLS, CULTURED; ENDOTHELIN-1; ENZYME ACTIVATION; FOCAL ADHESION KINASE 2; MUTATION; MYOCYTES, CARDIAC; PHENYLEPHRINE; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN-TYROSINE KINASES; RAC1 GTP-BINDING PROTEIN; RATS; REACTIVE OXYGEN SPECIES; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TRANSFECTION;

ADENOVIRIDAE;

EID: 2442609741     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2004.03.002     Document Type: Article

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