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Volumn 7, Issue 4, 2009, Pages 260-269

Female sexual dysfunction: Therapeutic options and experimental challenges

Author keywords

Clitoris; Female sexual dysfunction; Pudendal arteries; Vagina

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; 3 [2 (4 CHLOROPHENYLTHIO)PHENYL] N (4 DIMETHYLAMINOBUTYL)ACRYLAMIDE; 4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE; AMFEBUTAMONE; ANTIDEPRESSANT AGENT; APOMORPHINE; ARGININE; ARGINMAX; BREMELANOTIDE; CANDOXATRILAT; CONJUGATED ESTROGEN; DOPAMINE RECEPTOR STIMULATING AGENT; ESTRADIOL; ESTROGEN; INTRENSA; NITRIC OXIDE DONOR; NMI 870; PALATIN; PHENTOLAMINE; PHOSPHODIESTERASE V INHIBITOR; PLACEBO; PROSTAGLANDIN E1; SENSUA!; SILDENAFIL; TADALAFIL; TESTOSTERONE; TIBOLONE; UNCLASSIFIED DRUG; VARDENAFIL; VASOACTIVE INTESTINAL POLYPEPTIDE; YOHIMBINE;

EID: 74049162059     PISSN: 18715257     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152509789541882     Document Type: Review
Times cited : (67)

References (70)
  • 1
    • 51849158622 scopus 로고    scopus 로고
    • Women's sexual function and dysfunction: Current uncertainties, future directions
    • Basson, R. Women's sexual function and dysfunction: current uncertainties, future directions. Int. J. Impot. Res., 2008, 20, 466.
    • (2008) Int. J. Impot. Res , vol.20 , pp. 466
    • Basson, R.1
  • 2
    • 34548389238 scopus 로고    scopus 로고
    • Designing drugs for the treatment of female sexual dysfunction
    • Brown, A.D.; Blagg, J.; Reynolds, D.S. Designing drugs for the treatment of female sexual dysfunction. Drug Discov. Today, 2007, 12, 757.
    • (2007) Drug Discov. Today , vol.12 , pp. 757
    • Brown, A.D.1    Blagg, J.2    Reynolds, D.S.3
  • 3
    • 57749110444 scopus 로고    scopus 로고
    • Sexual dysfunction in women: What can urologists contribute?
    • Goldstein, I. Sexual dysfunction in women: what can urologists contribute? Curr. Urol. Rep., 2008, 9, 475.
    • (2008) Curr. Urol. Rep , vol.9 , pp. 475
    • Goldstein, I.1
  • 4
    • 0035097995 scopus 로고    scopus 로고
    • Measurement of vaginal and minor labial oxygen tension for the evaluation of female sexual function
    • Sommer, F.; Caspers, H.P.; Esders, K.; Klotz, T.; Engelmann, U. Measurement of vaginal and minor labial oxygen tension for the evaluation of female sexual function. J. Urol., 2001, 165, 1181.
    • (2001) J. Urol , vol.165 , pp. 1181
    • Sommer, F.1    Caspers, H.P.2    Esders, K.3    Klotz, T.4    Engelmann, U.5
  • 5
    • 47949098768 scopus 로고    scopus 로고
    • Magnetic resonance imaging and the female sexual response: Overview of techniques, results, and future directions
    • Maravilla, K.R.; Yang, C.C. Magnetic resonance imaging and the female sexual response: overview of techniques, results, and future directions. J. Sex Med., 2008, 5, 1559.
    • (2008) J. Sex Med , vol.5 , pp. 1559
    • Maravilla, K.R.1    Yang, C.C.2
  • 6
    • 84942949401 scopus 로고    scopus 로고
    • NIH Consensus Conference. Impotence. NIH Consensus Development Panel on Impotence. JAMA, 1993, 270, 83.
    • NIH Consensus Conference. Impotence. NIH Consensus Development Panel on Impotence. JAMA, 1993, 270, 83.
  • 8
    • 0018184279 scopus 로고
    • Frequency of sexual dysfunction in "normal" couples
    • Frank, E.; Anderson, C.; Rubinstein, D. Frequency of sexual dysfunction in "normal" couples. N. Engl. J. Med., 1978, 299, 111.
    • (1978) N. Engl. J. Med , vol.299 , pp. 111
    • Frank, E.1    Anderson, C.2    Rubinstein, D.3
  • 9
    • 0033540646 scopus 로고    scopus 로고
    • Sexual dysfunction in the United States: Prevalence and predictors
    • Laumann, E.O.; Paik, A.; Rosen, R.C. Sexual dysfunction in the United States: prevalence and predictors. JAMA, 1999, 281, 537.
    • (1999) JAMA , vol.281 , pp. 537
    • Laumann, E.O.1    Paik, A.2    Rosen, R.C.3
  • 10
    • 0028036149 scopus 로고
    • Impotence and its medical and psychosocial correlates: Results of the Massachusetts male aging study
    • Feldman, H.A.; Goldstein, I.; Hatzichristou, D.G.; Krane, R.J.; McKinlay, J.B. Impotence and its medical and psychosocial correlates: results of the Massachusetts male aging study. J. Urol., 1994, 151, 54.
    • (1994) J. Urol , vol.151 , pp. 54
    • Feldman, H.A.1    Goldstein, I.2    Hatzichristou, D.G.3    Krane, R.J.4    McKinlay, J.B.5
  • 11
    • 33845807862 scopus 로고    scopus 로고
    • Sexual dysfunctions: Classifications and definitions
    • Hatzimouratidis, K.; Hatzichristou, D. Sexual dysfunctions: classifications and definitions. J. Sex Med., 2007, 4, 241.
    • (2007) J. Sex Med , vol.4 , pp. 241
    • Hatzimouratidis, K.1    Hatzichristou, D.2
  • 12
    • 0032847368 scopus 로고    scopus 로고
    • Sexual dysfunction and the cardiac patient - no room for gender bias
    • Jackson, G. Sexual dysfunction and the cardiac patient - no room for gender bias. Int. J. Clin. Pract., 1999, 53, 411.
    • (1999) Int. J. Clin. Pract , vol.53 , pp. 411
    • Jackson, G.1
  • 13
    • 29544443156 scopus 로고    scopus 로고
    • Kostis, J.B.; Jackson, G.; Rosen, R.; Barrett-Connor, E.; Billups, K.; Burnett, A.L.; Carson, C., 3rd; Cheitlin, M.; Debusk, R.; Fonseca, V.; Ganz, P.; Goldstein, I.; Guay, A.; Hatzichristou, D.; Hollander, J.E.; Hutter, A.; Katz, S.; Kloner, R.A.; Mittleman, M.; Montorsi, F.; Montorsi, P.; Nehra, A.; Sadovsky, R.; Shabsigh, R. Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference). Am. J. Cardiol., 2005, 96, 85M.
    • Kostis, J.B.; Jackson, G.; Rosen, R.; Barrett-Connor, E.; Billups, K.; Burnett, A.L.; Carson, C., 3rd; Cheitlin, M.; Debusk, R.; Fonseca, V.; Ganz, P.; Goldstein, I.; Guay, A.; Hatzichristou, D.; Hollander, J.E.; Hutter, A.; Katz, S.; Kloner, R.A.; Mittleman, M.; Montorsi, F.; Montorsi, P.; Nehra, A.; Sadovsky, R.; Shabsigh, R. Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference). Am. J. Cardiol., 2005, 96, 85M.
  • 14
    • 38149087468 scopus 로고    scopus 로고
    • The prevalence and clinical relevance of sexual dysfunction in women and men with chronic heart failure
    • Schwarz, E.R.; Kapur, V.; Bionat, S.; Rastogi, S.; Gupta, R.; Rosanio, S. The prevalence and clinical relevance of sexual dysfunction in women and men with chronic heart failure. Int. J. Impot. Res., 2008, 20, 85.
    • (2008) Int. J. Impot. Res , vol.20 , pp. 85
    • Schwarz, E.R.1    Kapur, V.2    Bionat, S.3    Rastogi, S.4    Gupta, R.5    Rosanio, S.6
  • 15
    • 65149087305 scopus 로고    scopus 로고
    • Rosen, R.C.; Wing, R.R.; Schneider, S.; Wadden, T.A.; Foster, G.D.; West, D.S.; Kitabchi, A.E.; Brancati, F.L.; Maschak-Carey, B.J.; Bahnson, J.L.; Lewis, C.E.; Gendrano, I.N., 3rd. Erectile Dysfunction in type 2 diabetic men: relationship to exercise fitness and cardiovascular risk factors in the look AHEAD trial. J Sex Med., 2009, 6(5), 1414.
    • Rosen, R.C.; Wing, R.R.; Schneider, S.; Wadden, T.A.; Foster, G.D.; West, D.S.; Kitabchi, A.E.; Brancati, F.L.; Maschak-Carey, B.J.; Bahnson, J.L.; Lewis, C.E.; Gendrano, I.N., 3rd. Erectile Dysfunction in type 2 diabetic men: relationship to exercise fitness and cardiovascular risk factors in the look AHEAD trial. J Sex Med., 2009, 6(5), 1414.
  • 16
    • 59149085504 scopus 로고    scopus 로고
    • Evaluation of sexual function in women with type 2 diabetes mellitus
    • Fatemi, S.S.; Taghavi, S.M. Evaluation of sexual function in women with type 2 diabetes mellitus. Diab. Vasc. Dis. Res., 2009, 6, 38.
    • (2009) Diab. Vasc. Dis. Res , vol.6 , pp. 38
    • Fatemi, S.S.1    Taghavi, S.M.2
  • 17
    • 41549156061 scopus 로고    scopus 로고
    • Determinants of sexual function among women with type 2 diabetes in a Nigerian population
    • Olarinoye, J.; Olarinoye, A. Determinants of sexual function among women with type 2 diabetes in a Nigerian population. J. Sex Med., 2008, 5, 878.
    • (2008) J. Sex Med , vol.5 , pp. 878
    • Olarinoye, J.1    Olarinoye, A.2
  • 18
    • 28844479056 scopus 로고    scopus 로고
    • Sexual dysfunction in women with diabetes mellitus
    • Rutherford, D.; Collier, A. Sexual dysfunction in women with diabetes mellitus. Gynecol. Endocrinol., 2005, 21, 189.
    • (2005) Gynecol. Endocrinol , vol.21 , pp. 189
    • Rutherford, D.1    Collier, A.2
  • 19
    • 0022971169 scopus 로고
    • Sexual dysfunction in diabetic women
    • Newman, A.S.; Bertelson, A.D. Sexual dysfunction in diabetic women. J. Behav. Med., 1986, 9, 261.
    • (1986) J. Behav. Med , vol.9 , pp. 261
    • Newman, A.S.1    Bertelson, A.D.2
  • 21
    • 0035341458 scopus 로고    scopus 로고
    • The role of dopamine in the nucleus accumbens and striatum during sexual behavior in the female rat
    • Becker, J.B.; Rudick, C.N.; Jenkins, W.J. The role of dopamine in the nucleus accumbens and striatum during sexual behavior in the female rat. J. Neurosci., 2001, 21, 3236.
    • (2001) J. Neurosci , vol.21 , pp. 3236
    • Becker, J.B.1    Rudick, C.N.2    Jenkins, W.J.3
  • 22
    • 0038547816 scopus 로고    scopus 로고
    • Female rats develop conditioned place preferences for sex at their preferred interval
    • Jenkins, W.J.; Becker, J.B. Female rats develop conditioned place preferences for sex at their preferred interval. Horm. Behav., 2003, 43, 503.
    • (2003) Horm. Behav , vol.43 , pp. 503
    • Jenkins, W.J.1    Becker, J.B.2
  • 23
    • 0035099540 scopus 로고    scopus 로고
    • Role of the striatum and nucleus accumbens in paced copulatory behavior in the female rat
    • Jenkins, W.J.; Becker, J.B. Role of the striatum and nucleus accumbens in paced copulatory behavior in the female rat. Behav. Brain Res., 2001, 121, 119.
    • (2001) Behav. Brain Res , vol.121 , pp. 119
    • Jenkins, W.J.1    Becker, J.B.2
  • 24
    • 0028908661 scopus 로고
    • Increased extracellular dopamine in the nucleus accumbens and striatum of the female rat during paced copulatory behavior
    • Mermelstein, P.G.; Becker, J.B. Increased extracellular dopamine in the nucleus accumbens and striatum of the female rat during paced copulatory behavior. Behav. Neurosci., 1995, 109, 354.
    • (1995) Behav. Neurosci , vol.109 , pp. 354
    • Mermelstein, P.G.1    Becker, J.B.2
  • 25
    • 33750455847 scopus 로고    scopus 로고
    • Antidepressant-induced inhibition of genital vascular responses is reversed by vardenafil in female rabbits
    • Angulo, J.; Cuevas, P.; Cuevas, B.; Bischoff, E.; de Tejada, I.S. Antidepressant-induced inhibition of genital vascular responses is reversed by vardenafil in female rabbits. J. Sex Med., 2006, 3, 988.
    • (2006) J. Sex Med , vol.3 , pp. 988
    • Angulo, J.1    Cuevas, P.2    Cuevas, B.3    Bischoff, E.4    de Tejada, I.S.5
  • 26
    • 0030903202 scopus 로고    scopus 로고
    • Vasculogenic female sexual dysfunction: The hemodynamic basis for vaginal engorgement insufficiency and clitoral erectile insufficiency
    • Park, K.; Goldstein, I.; Andry, C.; Siroky, M.B.; Krane, R.J.; Azadzoi, K.M. Vasculogenic female sexual dysfunction: the hemodynamic basis for vaginal engorgement insufficiency and clitoral erectile insufficiency. Int. J. Impot. Res., 1997, 9, 27.
    • (1997) Int. J. Impot. Res , vol.9 , pp. 27
    • Park, K.1    Goldstein, I.2    Andry, C.3    Siroky, M.B.4    Krane, R.J.5    Azadzoi, K.M.6
  • 30
    • 42949090497 scopus 로고    scopus 로고
    • Contractile changes of the clitoral cavernous smooth muscle in female rabbits with experimentally induced overactive bladder
    • Myung, S.C.; Lee, M.Y.; Lee, S.Y.; Yum, S.H.; Park, S.H.; Kim, S.C. Contractile changes of the clitoral cavernous smooth muscle in female rabbits with experimentally induced overactive bladder. J. Sex Med., 2008, 5, 1088.
    • (2008) J. Sex Med , vol.5 , pp. 1088
    • Myung, S.C.1    Lee, M.Y.2    Lee, S.Y.3    Yum, S.H.4    Park, S.H.5    Kim, S.C.6
  • 31
    • 3342962358 scopus 로고    scopus 로고
    • Mechanisms of action of PDE5 inhibition in erectile dysfunction
    • Corbin, J.D. Mechanisms of action of PDE5 inhibition in erectile dysfunction. Int. J. Impot. Res., 2004, 16(Suppl. 1), S4.
    • (2004) Int. J. Impot. Res , vol.16 , Issue.SUPPL. 1
    • Corbin, J.D.1
  • 32
    • 63849246674 scopus 로고    scopus 로고
    • Discovery of the nitric oxide signaling pathway and targets for drug development
    • Bryan, N.S.; Bian, K.; Murad, F. Discovery of the nitric oxide signaling pathway and targets for drug development. Front. Biosci., 2009, 14, 1.
    • (2009) Front. Biosci , vol.14 , pp. 1
    • Bryan, N.S.1    Bian, K.2    Murad, F.3
  • 33
    • 33846863589 scopus 로고    scopus 로고
    • Nitric oxide and peroxynitrite in health and disease
    • Pacher, P.; Beckman, J.S.; Liaudet, L. Nitric oxide and peroxynitrite in health and disease. Physiol. Rev., 2007, 87, 315.
    • (2007) Physiol. Rev , vol.87 , pp. 315
    • Pacher, P.1    Beckman, J.S.2    Liaudet, L.3
  • 34
    • 0034861167 scopus 로고    scopus 로고
    • Effect of sildenafil on subjective and physiologic parameters of the female sexual response in women with sexual arousal disorder
    • Berman, J.R.; Berman, L.A.; Lin, H.; Flaherty, E.; Lahey, N.; Goldstein, I.; Cantey-Kiser, J. Effect of sildenafil on subjective and physiologic parameters of the female sexual response in women with sexual arousal disorder. J. Sex Marital. Ther., 2001, 27, 411.
    • (2001) J. Sex Marital. Ther , vol.27 , pp. 411
    • Berman, J.R.1    Berman, L.A.2    Lin, H.3    Flaherty, E.4    Lahey, N.5    Goldstein, I.6    Cantey-Kiser, J.7
  • 35
    • 0035380684 scopus 로고    scopus 로고
    • Premenopausal women affected by sexual arousal disorder treated with sildenafil: A double-blind, cross-over, placebo-controlled study
    • Caruso, S.; Intelisano, G.; Lupo, L.; Agnello, C. Premenopausal women affected by sexual arousal disorder treated with sildenafil: a double-blind, cross-over, placebo-controlled study. BJOG., 2001, 108, 623.
    • (2001) BJOG , vol.108 , pp. 623
    • Caruso, S.1    Intelisano, G.2    Lupo, L.3    Agnello, C.4
  • 37
    • 0036014125 scopus 로고    scopus 로고
    • Efficacy and safety of sildenafil citrate in women with sexual dysfunction associated with female sexual arousal disorder
    • Basson, R.; McInnes, R.; Smith, M.D.; Hodgson, G.; Koppiker, N. Efficacy and safety of sildenafil citrate in women with sexual dysfunction associated with female sexual arousal disorder. J. Womens Health Gend. Based Med., 2002, 11, 367.
    • (2002) J. Womens Health Gend. Based Med , vol.11 , pp. 367
    • Basson, R.1    McInnes, R.2    Smith, M.D.3    Hodgson, G.4    Koppiker, N.5
  • 38
    • 34249102899 scopus 로고    scopus 로고
    • Immunohistochemical description of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human labia minora
    • Uckert, S.; Oelke, M.; Albrecht, K.; Stief, C.; Jonas, U.; Hedlund, P. Immunohistochemical description of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human labia minora. J. Sex Med., 2007, 4, 602.
    • (2007) J. Sex Med , vol.4 , pp. 602
    • Uckert, S.1    Oelke, M.2    Albrecht, K.3    Stief, C.4    Jonas, U.5    Hedlund, P.6
  • 39
    • 0028183018 scopus 로고
    • International Union of Pharmacology classification of prostanoid receptors: Properties, distribution, and structure of the receptors and their subtypes
    • Coleman, R.A.; Smith, W.L.; Narumiya, S. International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol. Rev., 1994, 46, 205.
    • (1994) Pharmacol. Rev , vol.46 , pp. 205
    • Coleman, R.A.1    Smith, W.L.2    Narumiya, S.3
  • 40
    • 0038443357 scopus 로고    scopus 로고
    • Female sexual dysfunction: Potential for pharmacotherapy
    • Fourcroy, J.L. Female sexual dysfunction: potential for pharmacotherapy. Drugs, 2003, 63, 1445.
    • (2003) Drugs , vol.63 , pp. 1445
    • Fourcroy, J.L.1
  • 41
    • 33747018230 scopus 로고    scopus 로고
    • Topical alprostadil treatment of female sexual arousal disorder
    • Kielbasa, L.A.; Daniel, K.L. Topical alprostadil treatment of female sexual arousal disorder. Ann. Pharmacother., 2006, 40, 1369.
    • (2006) Ann. Pharmacother , vol.40 , pp. 1369
    • Kielbasa, L.A.1    Daniel, K.L.2
  • 42
    • 48749123439 scopus 로고    scopus 로고
    • Efficacy and safety of alprostadil cream for the treatment of female sexual arousal disorder: A double-blind, placebo-controlled study in chinese population
    • Liao, Q.; Zhang, M.; Geng, L.; Wang, X.; Song, X.; Xia, P.; Lu, T.; Lu, M.; Liu, V. Efficacy and safety of alprostadil cream for the treatment of female sexual arousal disorder: a double-blind, placebo-controlled study in chinese population. J. Sex Med., 2008, 5, 1923.
    • (2008) J. Sex Med , vol.5 , pp. 1923
    • Liao, Q.1    Zhang, M.2    Geng, L.3    Wang, X.4    Song, X.5    Xia, P.6    Lu, T.7    Lu, M.8    Liu, V.9
  • 43
    • 0347133468 scopus 로고    scopus 로고
    • Topical administration of a novel nitric oxide donor, linear polyethylenimine-nitric oxide/nucleophile adduct (DS1), selectively increases vaginal blood flow in anesthetized rats
    • Pacher, P.; Mabley, J.G.; Liaudet, L.; Evgenov, O.V.; Southan, G.J.; Abdelkarim, G.E.; Szabo, C.; Salzman, A.L. Topical administration of a novel nitric oxide donor, linear polyethylenimine-nitric oxide/nucleophile adduct (DS1), selectively increases vaginal blood flow in anesthetized rats. Int. J. Impot. Res., 2003, 15, 461.
    • (2003) Int. J. Impot. Res , vol.15 , pp. 461
    • Pacher, P.1    Mabley, J.G.2    Liaudet, L.3    Evgenov, O.V.4    Southan, G.J.5    Abdelkarim, G.E.6    Szabo, C.7    Salzman, A.L.8
  • 44
    • 33748312096 scopus 로고    scopus 로고
    • NO-independent stimulators and activators of soluble guanylate cyclase: Discovery and therapeutic potential
    • Evgenov, O.V.; Pacher, P.; Schmidt, P.M.; Hasko, G.; Schmidt, H.H.; Stasch, J.P. NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential. Nat. Rev. Drug Discov., 2006, 5, 755.
    • (2006) Nat. Rev. Drug Discov , vol.5 , pp. 755
    • Evgenov, O.V.1    Pacher, P.2    Schmidt, P.M.3    Hasko, G.4    Schmidt, H.H.5    Stasch, J.P.6
  • 45
    • 0036674514 scopus 로고    scopus 로고
    • The effects of yohimbine plus L-arginine glutamate on sexual arousal in postmenopausal women with sexual arousal disorder
    • Meston, C.M.; Worcel, M. The effects of yohimbine plus L-arginine glutamate on sexual arousal in postmenopausal women with sexual arousal disorder. Arch. Sex Behav., 2002, 31, 323.
    • (2002) Arch. Sex Behav , vol.31 , pp. 323
    • Meston, C.M.1    Worcel, M.2
  • 46
    • 3042741857 scopus 로고    scopus 로고
    • What can animal models tell us about human sexual response?
    • Pfaus, J.G.; Kippin, T.E.; Coria-Avila, G. What can animal models tell us about human sexual response? Annu. Rev. Sex Res., 2003, 14, 1.
    • (2003) Annu. Rev. Sex Res , vol.14 , pp. 1
    • Pfaus, J.G.1    Kippin, T.E.2    Coria-Avila, G.3
  • 47
    • 33748509086 scopus 로고    scopus 로고
    • The enhancement of female sexual function with ArginMax, a nutritional supplement, among women differing in menopausal status
    • Ito, T.Y.; Polan, M.L.; Whipple, B.; Trant, A.S. The enhancement of female sexual function with ArginMax, a nutritional supplement, among women differing in menopausal status. J. Sex Marital. Ther., 2006, 32, 369.
    • (2006) J. Sex Marital. Ther , vol.32 , pp. 369
    • Ito, T.Y.1    Polan, M.L.2    Whipple, B.3    Trant, A.S.4
  • 48
    • 0034861367 scopus 로고    scopus 로고
    • A double-blind placebocontrolled study of ArginMax, a nutritional supplement for enhancement of female sexual function
    • Ito, T.Y.; Trant, A.S.; Polan, M.L. A double-blind placebocontrolled study of ArginMax, a nutritional supplement for enhancement of female sexual function. J. Sex Marital. Ther., 2001, 27, 541.
    • (2001) J. Sex Marital. Ther , vol.27 , pp. 541
    • Ito, T.Y.1    Trant, A.S.2    Polan, M.L.3
  • 50
    • 0020565661 scopus 로고
    • Vasoactive intestinal polypeptide (VIP) increases vaginal blood flow and inhibits uterine smooth muscle activity in women
    • Ottesen, B.; Gerstenberg, T.; Ulrichsen, H.; Manthorpe, T.; Fahrenkrug, J.; Wagner, G. Vasoactive intestinal polypeptide (VIP) increases vaginal blood flow and inhibits uterine smooth muscle activity in women. Eur. J. Clin. Invest., 1983, 13, 321.
    • (1983) Eur. J. Clin. Invest , vol.13 , pp. 321
    • Ottesen, B.1    Gerstenberg, T.2    Ulrichsen, H.3    Manthorpe, T.4    Fahrenkrug, J.5    Wagner, G.6
  • 51
    • 0030845208 scopus 로고    scopus 로고
    • Formation and pharmacokinetics of the active drug candoxatrilat in mouse, rat, rabbit, dog and man following administration of the prodrug candoxatril
    • Kaye, B.; Brearley, C.J.; Cussans, N.J.; Herron, M.; Humphrey, M.J.; Mollatt, A.R. Formation and pharmacokinetics of the active drug candoxatrilat in mouse, rat, rabbit, dog and man following administration of the prodrug candoxatril. Xenobiotica, 1997, 27, 1091.
    • (1997) Xenobiotica , vol.27 , pp. 1091
    • Kaye, B.1    Brearley, C.J.2    Cussans, N.J.3    Herron, M.4    Humphrey, M.J.5    Mollatt, A.R.6
  • 52
    • 77149121584 scopus 로고    scopus 로고
    • Ziegler, D.; Witte, K.; Straub, M.; Weske, M. Medicaments containing dually acting inhibitors of neutral endopeptidase and of human soluble endopeptidase for the treatment of sexual dysfunction. (WO/2005/112939). 2005. Available from http://www.wipo.int/pctdb/en/wo.jsp?wo=2005112939
    • Ziegler, D.; Witte, K.; Straub, M.; Weske, M. Medicaments containing dually acting inhibitors of neutral endopeptidase and of human soluble endopeptidase for the treatment of sexual dysfunction. (WO/2005/112939). 2005. Available from http://www.wipo.int/pctdb/en/wo.jsp?wo=2005112939
  • 53
    • 26044461651 scopus 로고    scopus 로고
    • The endocrinology of sexual arousal
    • Bancroft, J. The endocrinology of sexual arousal. J. Endocrinol., 2005, 186, 411.
    • (2005) J. Endocrinol , vol.186 , pp. 411
    • Bancroft, J.1
  • 54
    • 0036255112 scopus 로고    scopus 로고
    • Sexual effects of androgens in women: Some theoretical considerations
    • Bancroft, J. Sexual effects of androgens in women: some theoretical considerations. Fertil. Steril., 2002, 77(Suppl. 4), S55.
    • (2002) Fertil. Steril , vol.77 , Issue.SUPPL. 4
    • Bancroft, J.1
  • 55
    • 0033765498 scopus 로고    scopus 로고
    • Androgens and female sexuality
    • Davis, S.R. Androgens and female sexuality. J. Gend. Specif. Med., 2000, 3, 36.
    • (2000) J. Gend. Specif. Med , vol.3 , pp. 36
    • Davis, S.R.1
  • 58
    • 33745231170 scopus 로고    scopus 로고
    • Efficacy and safety of a testosterone patch for the treatment of hypoactive sexual desire disorder in surgically menopausal women: A randomized, placebo-controlled trial
    • Davis, S.R.; van der Mooren, M.J.; van Lunsen, R.H.; Lopes, P.; Ribot, C.; Rees, M.; Moufarege, A.; Rodenberg, C.; Buch, A.; Purdie, D.W. Efficacy and safety of a testosterone patch for the treatment of hypoactive sexual desire disorder in surgically menopausal women: a randomized, placebo-controlled trial. Menopause, 2006, 13, 387.
    • (2006) Menopause , vol.13 , pp. 387
    • Davis, S.R.1    van der Mooren, M.J.2    van Lunsen, R.H.3    Lopes, P.4    Ribot, C.5    Rees, M.6    Moufarege, A.7    Rodenberg, C.8    Buch, A.9    Purdie, D.W.10
  • 59
    • 23744435191 scopus 로고    scopus 로고
    • Goldilocks and menopause
    • Vigersky, R.A. Goldilocks and menopause. Arch. Intern. Med., 2005, 165, 1571.
    • (2005) Arch. Intern. Med , vol.165 , pp. 1571
    • Vigersky, R.A.1
  • 60
    • 30044441385 scopus 로고    scopus 로고
    • Physiology of female sexual function and dysfunction
    • Berman, J.R. Physiology of female sexual function and dysfunction. Int. J. Impot. Res., 2005, 17(Suppl. 1), S44.
    • (2005) Int. J. Impot. Res , vol.17 , Issue.SUPPL. 1
    • Berman, J.R.1
  • 61
    • 64049083020 scopus 로고    scopus 로고
    • Effect of one-week treatment with vaginal estrogen preparations on serum estrogen levels in postmenopausal women
    • Labrie, F.; Cusan, L.; Gomez, J.L.; Cote, I.; Berube, R.; Belanger, P.; Martel, C.; Labrie, C. Effect of one-week treatment with vaginal estrogen preparations on serum estrogen levels in postmenopausal women. Menopause, 2009, 16, 30.
    • (2009) Menopause , vol.16 , pp. 30
    • Labrie, F.1    Cusan, L.2    Gomez, J.L.3    Cote, I.4    Berube, R.5    Belanger, P.6    Martel, C.7    Labrie, C.8
  • 63
    • 0034916235 scopus 로고    scopus 로고
    • Double-blind, crossover comparison of 3 mg apomorphine SL with placebo and with 4 mg apomorphine SL in male erectile dysfunction
    • Dula, E.; Bukofzer, S.; Perdok, R.; George, M. Double-blind, crossover comparison of 3 mg apomorphine SL with placebo and with 4 mg apomorphine SL in male erectile dysfunction. Eur. Urol., 2001, 39, 558.
    • (2001) Eur. Urol , vol.39 , pp. 558
    • Dula, E.1    Bukofzer, S.2    Perdok, R.3    George, M.4
  • 64
    • 57649129152 scopus 로고    scopus 로고
    • An open-label, randomized, flexible-dose, crossover study to assess the comparative efficacy and safety of sildenafil citrate and apomorphine hydrochloride in men with erectile dysfunction
    • Giammusso, B.; Colpi, G.M.; Cormio, L.; Ludovico, G.; Soli, M.; Ponchietti, R.; Montorsi, F.; Panzironi, C.; Guastella, B. An open-label, randomized, flexible-dose, crossover study to assess the comparative efficacy and safety of sildenafil citrate and apomorphine hydrochloride in men with erectile dysfunction. Urol. Int., 2008, 81, 409.
    • (2008) Urol. Int , vol.81 , pp. 409
    • Giammusso, B.1    Colpi, G.M.2    Cormio, L.3    Ludovico, G.4    Soli, M.5    Ponchietti, R.6    Montorsi, F.7    Panzironi, C.8    Guastella, B.9
  • 65
    • 0033948455 scopus 로고    scopus 로고
    • Effect of bupropion-SR on orgasmic dysfunction in nondepressed subjects: A pilot study
    • Modell, J.G.; May, R.S.; Katholi, C.R. Effect of bupropion-SR on orgasmic dysfunction in nondepressed subjects: a pilot study. J. Sex Marital. Ther., 2000, 26, 231.
    • (2000) J. Sex Marital. Ther , vol.26 , pp. 231
    • Modell, J.G.1    May, R.S.2    Katholi, C.R.3
  • 66
    • 15844425802 scopus 로고    scopus 로고
    • A double-blind randomized placebo control study comparing the objective and subjective changes in female sexual response using sublingual apomorphine
    • Bechara, A.; Bertolino, M.V.; Casabe, A.; Fredotovich, N.A double-blind randomized placebo control study comparing the objective and subjective changes in female sexual response using sublingual apomorphine. J. Sex Med., 2004, 1, 209.
    • (2004) J. Sex Med , vol.1 , pp. 209
    • Bechara, A.1    Bertolino, M.V.2    Casabe, A.3    Fredotovich, N.4
  • 67
    • 2342563100 scopus 로고    scopus 로고
    • Placebo-controlled study on efficacy and safety of daily apomorphine SL intake in premenopausal women affected by hypoactive sexual desire disorder and sexual arousal disorder
    • Caruso, S.; Agnello, C.; Intelisano, G.; Farina, M.; Di Mari, L.; Cianci, A. Placebo-controlled study on efficacy and safety of daily apomorphine SL intake in premenopausal women affected by hypoactive sexual desire disorder and sexual arousal disorder. Urology, 2004, 63, 955.
    • (2004) Urology , vol.63 , pp. 955
    • Caruso, S.1    Agnello, C.2    Intelisano, G.3    Farina, M.4    Di Mari, L.5    Cianci, A.6
  • 68
    • 37349065765 scopus 로고    scopus 로고
    • Modulation of brain delivery and copulation by intranasal apomorphine hydrochloride
    • Lu, W.; Jiang, W.; Chen, J.; Yin, M.; Wang, Z.; Jiang, X. Modulation of brain delivery and copulation by intranasal apomorphine hydrochloride. Int. J. Pharm., 2008, 349, 196.
    • (2008) Int. J. Pharm , vol.349 , pp. 196
    • Lu, W.1    Jiang, W.2    Chen, J.3    Yin, M.4    Wang, Z.5    Jiang, X.6
  • 69
    • 51349164299 scopus 로고    scopus 로고
    • Pharmacological profiling of neuropeptides on rabbit vaginal wall and vaginal artery smooth muscle in vitro
    • Aughton, K.L.; Hamilton-Smith, K.; Gupta, J.; Morton, J.S.; Wayman, C.P.; Jackson, V.M. Pharmacological profiling of neuropeptides on rabbit vaginal wall and vaginal artery smooth muscle in vitro. Br. J. Pharmacol., 2008, 155, 236.
    • (2008) Br. J. Pharmacol , vol.155 , pp. 236
    • Aughton, K.L.1    Hamilton-Smith, K.2    Gupta, J.3    Morton, J.S.4    Wayman, C.P.5    Jackson, V.M.6
  • 70
    • 35648981057 scopus 로고    scopus 로고
    • Clinical application of CNS-acting agents in FSD
    • Perelman, M.A. Clinical application of CNS-acting agents in FSD. J. Sex Med., 2007, 4(Suppl. 4), 280.
    • (2007) J. Sex Med , vol.4 , Issue.SUPPL. 4 , pp. 280
    • Perelman, M.A.1


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