Sexual dysfunction in women: What can urologists contribute?

Current Urology Reports

Volumn 9, Issue 6, 2008, Pages 475-482

  Goldstein, Irwin ^a  

^a ALVARADO HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREMELANOTIDE;

ANDROGEN THERAPY; FEMALE; FEMALE INFERTILITY; FEMALE SEXUAL DYSFUNCTION; HEALTH CARE DELIVERY; HEALTH CARE PERSONNEL; HUMAN; MALE SEXUAL DYSFUNCTION; MARITAL THERAPY; NONHUMAN; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; REVIEW; SEXUAL HEALTH; URINARY TRACT DISEASE; VAGINA RECONSTRUCTION;

ANIMALS; FEMALE; HUMANS; SEXUAL DYSFUNCTION, PHYSIOLOGICAL; UROLOGY;

EID: 57749110444     PISSN: 15272737     EISSN: 15346285     Source Type: Journal    
DOI: 10.1007/s11934-008-0081-5     Document Type: Review

References (46)

1. Goldstein I: Female sexual dysfunction and the central nervous system. J Sex Med 2007, 4(Suppl 4):255-256.
2. Kingsberg S, Goldstein I: The journal of sexual medicine supports research and choice in women's sexual health management. J Sex Med 2007, 4(Suppl 3):209-210.
3. Goldstein I: Addressing both genders in sexual medicine diagnosis and treatment. J Sex Med 2006, 3:949-951.
4. Greenstein A, Ben-Aroya Z, Fass O, et al.: Vulvar vestibulitis syndrome and estrogen dose of oral contraceptive pills. J Sex Med 2007, 4:1679-1683. This study assessed the relationship between estrogen dose of oral contraceptives and prevalence of the sexual pain disorder, vulvar vestibulitis syndrome. In women with vulvar vestibulitis syndrome, significantly more used low-dose estrogen oral contraceptives. Although more research is needed related to the relationship of hormones to vulvar vestibulitis syndrome, hormones are critical for genital structure and function, including minor vestibular glands.
5. Wimpissinger F, Stifter K, Grin W, Stackl W: The female prostate revisited: perineal ultrasound and biochemical studies of female ejaculate. J Sex Med 2007, 4:1388-1393. In two women who ejaculated during orgasm, ultrasound images revealed gland tissue surrounding the female urethra, urethroscopy revealed an orifice to a duct and biochemical analysis of the ejaculate revealed high levels of prostate-specific antigen and low levels of creatinine and blood urea nitrogen. In these women, evidence of a female prostate gland was suggested.
6. Salonia A, Fabbri F, Zanni G, et al.: Chocolate and women's sexual health: an intriguing correlation. J Sex Med 2006, 3:476-482.
7. Scott FB, Bradley WE, Timm GW: Management of erectile impotence. Use of implantable inflatable prosthesis. Urology 1973, 2:80-82.
8. Small MP, Carrion HM, Gordon JA: Small-carrion penile prosthesis. New implant for management of impotence. Urology 1975, 5:479-486.
9. Lewis R, Wagner G: History of the International Society of Sexual Medicine (ISSM) - the beginnings. J Sex Med 2008, 5:740-745.
10. Coyne KS, Margolis MK, Jumadilova Z, et al.: Overactive bladder and women's sexual health: what is the impact? J Sex Med 2007, 4:656-666. A descriptive and qualitative study was conducted to assess sexual health using focus groups of women with overactive bladder, some continent and some incontinent. Overactive bladder with or without incontinence was found to negatively affect women's sexual health, lowering sexual desire and diminishing orgasm.
11. Whitmore K, Siegel JF, Kellogg-Spadt S: Interstitial cystitis/painful bladder syndrome as a cause of sexual pain in women: a diagnosis to consider. J Sex Med 2007, 4:720-727. The symptoms of interstitial cystitis/painful bladder syndrome are urinary urgency, frequency, dyspareunia, nocturia, and pelvic pain. Based on a review of the medical literature, many women with interstitial cystitis/painful bladder syndrome were found to experience dyspareunia. Interstitial cystitis/painful bladder syndrome is one potential cause of dyspareunia that may frequently be overlooked by clinicians.
12. Coyne KS, Margolis MK, Brewster-Jordan J, et al.: Evaluating the impact of overactive bladder on sexual health in women: what is relevant? J Sex Med 2007, 4:124-136.
13. Smith KB, Tripp D, Pukall C, Nickel JC: Predictors of sexual and relationship functioning in couples with chronic prostatitis/chronic pelvic pain syndrome. J Sex Med 2007, 4:734-744.
14. Garos S, Kluck A, Aronoff D: Prostate cancer patients and their partners: differences in satisfaction indices and psychological variables. J Sex Med 2007, 4:1394-1403.
15. Shindel A, Quayle S, Yan Y, et al.: Sexual dysfunction in female partners of men who have undergone radical prostatectomy correlates with sexual dysfunction of the male partner. J Sex Med 2005, 2:833-841.
16. Perelman MA: A new combination treatment for premature ejaculation: a sex therapist's perspective. J Sex Med 2006, 3:1004-1012.
17. Goldstein I, Fisher WA, Sand M, et al.: Women's sexual function improves when partners are administered vardenafil for erectile dysfunction: a prospective, randomized, double-blind, placebo-controlled trial. J Sex Med 2005, 2:819-832. A randomized, double-blind, placebo-controlled, multi-institutional comparison of vardenafil versus placebo was performed in 229 couples (treated men with ED > 6 months and untreated women partners). Compared with placebo, vardenafil use in men with ED significantly increased total FSFI and sexual desire, subjective arousal, lubrication, orgasm, and satisfaction domains in untreated women partners. Treatment-related improvement in erectile function was correlated reliably with improvement in women partners' FSFI total and individual domain scores.
18. Edwards D, Hackett G, Collins O, Curram J: Vardenafil improves sexual function and treatment satisfaction in couples affected by erectile dysfunction (ED): a randomized, double-blind, placebo-controlled trial in PDE5 inhibitor-naïve men with ED and their partners. J Sex Med 2006, 3:1028-1036.
19. Bain J, Brock G, Kuzmarov I, International Consulting Group: Canadian Society for the Study of the Aging Male: response to Health Canada's position paper on testosterone treatment. J Sex Med 2007, 4:558-566.
20. Panzer C, Wise S, Fantini G, et al.: Impact of oral contraceptives on sex hormone-binding globulin and androgen levels: a retrospective study in women with sexual dysfunction. J Sex Med 2006, 3:104-113. Women who take oral contraceptive pills have high values of SHBG (about five times those who have never used them) and are thus likely to have testosterone deficiency. Women who used oral contraceptives and then discontinued had their SHBG levels fall compared with when they were on these pills. The values of SHGB in women who discontinued oral contraceptives, however, were two times higher than in those women who never used oral contraceptives. The possibility of ethinyl estradiol imprinting a new and chronic message to the liver to synthesize higher levels of SHBG needs further investigation.
21. Lue TF, Giuliano F, Montorsi F, et al.: Summary of the recommendations on sexual dysfunctions in men. J Sex Med 2004, 1:6-23.
22. Goldstein I: Current management strategies of the postmenopausal patient with sexual health problems. J Sex Med 2007, 4:235-253.
23. Goddard JC, Vickery RM, Terry TR: Development of feminizing genitoplasty for gender dysphoria. J Sex Med 2007, 4:981-989.
24. Sohn M, Bosinski HA: Gender identity disorders: diagnostic and surgical aspects. J Sex Med 2007, 4:1193-1207.
25. Onol FF, Ercan F, Tarcan T: The effect of ovariectomy on rat vaginal tissue contractility and histomorphology. J Sex Med 2006, 3:233-241.
26. Pessina MA, Hoyt RF Jr, Goldstein I, Traish AM: Differential regulation of the expression of estrogen, progesterone, and androgen receptors by sex steroid hormones in the vagina: immunohistochemical studies. J Sex Med 2006, 3:804-814.
27. Traish AM, Kim SW, Stankovic M, et al.: Testosterone increases blood flow and expression of androgen and estrogen receptors in the rat vagina. J Sex Med 2007, 4:609-619.
28. Uckert S, Ellinghaus P, Albrecht K, et al.: Expression of messenger ribonucleic acid encoding for phosphodiesterase isoenzymes in human female genital tissues. J Sex Med 2007, 4:1604-1609.
29. Uckert S, Oelke M, Albrecht K, et al.: Immunohistochemical description of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human labia minora. J Sex Med 2007, 4:602-608.
30. Angulo J, Cuevas P, Cuevas B, et al.: Antidepressant-induced inhibition of genital vascular responses is reversed by vardenafil in female rabbits. J Sex Med 2006, 3:988-995.
31. Hatzimouratidis K, Hatzichristou D: Sexual dysfunctions: classifications and definitions. J Sex Med 2007, 4:241-250.
32. Smith LJ, Mulhall JP, Deveci S, et al.: Sex after seventy: a pilot study of sexual function in older persons. J Sex Med 2007, 4:1247-1253.
33. Shindel AW, Ferguson GG, Nelson CJ, Brandes SB: The sexual lives of medical students: a single institution survey. J Sex Med 2008, 5:796-803.
34. Bae JH, Han CS, Kang SH, et al.: Development of a Korean version of the female sexual distress scale. J Sex Med 2006, 3:1013-1017.
35. Kukkonen TM, Binik YM, Amsel R, Carrier S: Thermography as a physiological measure of sexual arousal in both men and women. J Sex Med 2007, 4:93-105.
36. Gruenwald I, Lowenstein L, Gartman I, Vardi Y: Physiological changes in female genital sensation during sexual stimulation. J Sex Med 2007, 4:390-394.
37. Toblli JE, Cao G, Casabé AR, Bechara AJ: Effects of ACE inhibition and beta-blockade on female genital structures in spontaneously hypertensive rats. J Sex Med 2007, 4:1593-1603.
38. Guess MK, Connell K, Schrader S, et al.: Genital sensation and sexual function in women bicyclists and runners: are your feet safer than your seat? J Sex Med 2006, 3:1018-1027.
39. Elzevier HW, Nieuwkamer BB, Pelger RC, et al.: Female sexual function and activity following cystectomy and continent urinary tract diversion for benign indications: a clinical pilot study and review of literature. J Sex Med 2007, 4:406-416.
40. Elzevier HW, Putter H, Delaere KP, et al.: Female sexual function after surgery for stress urinary incontinence: transobturator suburethral tape vs. tension-free vaginal tape obturator. J Sex Med 2008, 5:400-406.
41. Traish A, Guay AT, Spark RF, Testosterone Therapy in Women Study Group: Are the Endocrine Society's Clinical Practice Guidelines on Androgen Therapy in Women misguided? A commentary. J Sex Med 2007, 4:1223-1234.
42. Pfaus J, Giuliano F, Gelez H: Bremelanotide: an overview of preclinical CNS effects on female sexual function. J Sex Med 2007, 4(Suppl 4):269-279.
43. Song SH, Jeon H, Kim SW, et al.: The prevalence and risk factors of female sexual dysfunction in young Korean women: an internet-based survey. J Sex Med 2008 Apr 15 (Epub ahead of print).
44. Hayes RD, Dennerstein L, Bennett CM, et al.: Risk factors for female sexual dysfunction in the general population: exploring factors associated with low sexual function and sexual distress. J Sex Med 2008 Apr 11 (Epub ahead of print).
45. Mulhall J, King R, Glina S, Hvidsten K: Importance of and satisfaction with sex among men and women worldwide: results of the global better sex survey. J Sex Med 2008, 5:788-795.
46. Hayes RD, Dennerstein L, Bennett CM, Fairley CK: What is the "true" prevalence of female sexual dysfunctions and does the way we assess these conditions have an impact? J Sex Med 2008, 5:777-787.