Rapamycin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and induction of apoptosis

International Journal of Cancer

Volumn 126, Issue 5, 2010, Pages 1144-1154

  Shafer, Aaron ^a   Zhou, Chunxiao ^a   Gehrig, Paola A ^a   Boggess, John F ^a   Bae Jump, Victoria L ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Endometrial cancer; mTOR pathway; Paclitaxel; Rapamycin; Telomerase

Indexed keywords

INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; PACLITAXEL; PROTEIN S6; RAPAMYCIN; TELOMERASE; TUBULIN;

ACETYLATION; APOPTOSIS; ARTICLE; CANCER CELL; CANCER COMBINATION CHEMOTHERAPY; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; ENDOMETRIUM CANCER; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN POLYMERIZATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; PACLITAXEL; PROTEIN KINASES; SIGNAL TRANSDUCTION; SIROLIMUS; TELOMERASE; TUBULIN;

EID: 74049128836     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24837     Document Type: Article

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