Practical and efficient synthesis of pyrano[3,2-c]pyridone, pyrano[4,3-b]pyran and their hybrids with nucleoside as potential antiviral and antileishmanial agents

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 3, 2010, Pages 809-813

  Fan, Xuesen ^a   Feng, Dong ^a   Qu, Yingying ^a   Zhang, Xinying ^a   Wang, Jianji ^a   Loiseau, Philippe M ^b   Andrei, Graciela ^c   Snoeck, Robert ^c   Clercq, Erik De ^c  

^a HENAN NORMAL UNIVERSITY   (China)

^b UNIVERSITÉ PARIS SUD   (France)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Antileishmanial agents; Antivirals; Hybrid compounds; Ionic liquids; Pyrano 3,2 c pyridone; Pyrano 4,3 b pyran; Pyrimidine nucleoside

Indexed keywords

ALDEHYDE; ANTILEISHMANIAL AGENT; ANTIVIRUS AGENT; NITRILE; PYRAN DERIVATIVE; PYRANO[3,2 C]PYRIDONE; PYRANO[4,3 B]PYRAN DERIVATIVE; PYRIDINE DERIVATIVE; PYRIDONE DERIVATIVE; PYRIMIDINE NUCLEOSIDE; UNCLASSIFIED DRUG; ANTIPROTOZOAL AGENT; NUCLEOSIDE;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG SYNTHESIS; EMBRYO; HUMAN; HUMAN CELL; HYBRID; LEISHMANIA; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; CELL LINE; COMPARATIVE STUDY; DRUG EFFECTS; LEISHMANIA DONOVANI; PHYSIOLOGY; SYNTHESIS;

ANTIPROTOZOAL AGENTS; ANTIVIRAL AGENTS; CELL LINE; HUMANS; LEISHMANIA DONOVANI; NUCLEOSIDES; PYRANS; PYRIDONES; PYRIMIDINE NUCLEOSIDES;

EID: 74049100572     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.12.102     Document Type: Article

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