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Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 12, 2006, Pages 3224-3228

A pyrimidine-pyrazolone nucleoside chimera with potent in vitro anti-orthopoxvirus activity

(6) Fan, Xuesen a Zhang, Xinying a Zhou, Longhu a Keith, Kathy A b Kern, Earl R b Torrence, Paul F a

a NORTHERN ARIZONA UNIVERSITY (United States)

b UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE (United States)

Author keywords

5 Formyl 2 deoxyuridine; Cowpox virus; Privileged drug scaffold; Smallpox; Vaccinia virus

Indexed keywords

CIDOFOVIR; PYRAZOLONE; PYRIMIDINE NUCLEOSIDE; ANTIVIRUS AGENT; NUCLEOSIDE; PYRAZOLONE DERIVATIVE; PYRIMIDINE; PYRIMIDINE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; COWPOX VIRUS; HYBRIDIZATION; NONHUMAN; ORTHOPOXVIRUS; SUBSTITUTION REACTION; VACCINIA VIRUS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; VIRUS REPLICATION;

COWPOX VIRUS; ORTHOPOXVIRUS; VACCINIA VIRUS; VARIOLA VIRUS;

ANTIVIRAL AGENTS; MOLECULAR STRUCTURE; NUCLEOSIDES; ORTHOPOXVIRUS; PYRAZOLONES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

EID: 33747095922 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2006.03.043 Document Type: Article

Times cited : (79)

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