General method for the preparation of substituted 2-amino-4H,5H-pyrano[4,3- b]pyran-5-ones and 2-Amino-4H-pyrano[3,2-c]pyridine-5-ones

Molecules

Volumn 5, Issue 1, 2000, Pages 19-32

  Stoyanov, Edmont V ^a   Ivanov, Ivo C ^a   Heber, Dieter ^b  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^b UNIVERSITY OF KIEL   (Germany)

Author keywords

Aryl methylene cyanoacetate; Arylmethylene malononitrile; Michael addition; Pyrano 3,2 c pyridine; Pyrano 4,3 b pyran

Indexed keywords

4 HYDROXY 6 METHYL 2 PYRONE; NITRILE; PYRAN DERIVATIVE; PYRIDINE DERIVATIVE; PYRIDONE DERIVATIVE; PYRONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; MICHAEL ADDITION;

EID: 0002116611     PISSN: 14203049     EISSN: None     Source Type: Journal    
DOI: 10.3390/50100019     Document Type: Article

References (8)

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2. Junek, H.; Aigner, H. Synthesen mit Nitrilen, XXXV. Reaktionen von Tetracyanäthylen mit Heterocyclen. Chem. Ber. 1973, 106, 914-921.
3. Shaker, R. M. Synthesis and reactions of some new 4H-Pyrano[3,2-c] benzopyran-5-one derivatives and their potential biological activities. Pharmazie 1996, 51, 148-151.
4. Ivanov, I. C.; Stoyanov, E. V.; Denkova, P. S.; Dimitrov, V. S. Synthesis of Substituted 1,2-Dihydro-2-imino-7-methyl-1,6(6H)-naphthyridin-5-ones. Liebigs Ann. / Recueil 1997, 8, 1777-1781.
5. Stoyanov, E. V.; Ivanov, I. C. Synthesis of Some Substituted 2H-Pyrano[3,2-c]pyridine-2,5(6H)-diones. Reaction of Their 3-Acetyl Derivatives with Methyl 3-Amino-2-butenoate. Synth. Commun. 1998, 28 (10), 1755-1767.
6. Mekheimer, R. A.; Mohamed, N. H.; Sadek, K. U. Synthesis of Functionalized 4H-Pyrano-[3,2-c]pyridines from 4-Hydroxy-6-methyl-2-pyridone and Their Reactions. Unexpected New Routes to 3,3′-Benzylidene-bis[4-hydroxy- 6-methyl-2(1H)-3-pyridinones]. Bull. Chem. Soc. Japan 1997, 70, 1625-1630.
7. Piao, M.-Z.; Imafuku K. Convenient Synthesis of Amino-substituted Pyranopyranones. Tetrahedron Lett. 1997, 38, 5301-5302.
8. Prepared according to the general procedure C in Organicum; 17. Auflage, VEB Deutscher Verlag der Wissenschaften: Berlin, 1988, pp 460-461.