Enhanced osteoclastogenesis causes osteopenia in twisted gastrulation-deficient mice through increased BMP signaling

Journal of Bone and Mineral Research

Volumn 24, Issue 11, 2009, Pages 1917-1926

  Sotillo Rodriguez, Julio E ^a   Mansky, Kim C ^a   Jensen, Eric D ^a   Carlson, Ann E ^a   Schwarz, Toni ^a   Pham, Lan ^a   MacKenzie, Breanne ^b   Prasad, Hari ^a   Rohrer, Michael D ^a   Petryk, Anna ^b,c   Gopalakrishnan, Rajaram ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Bone; Bone morphogenetic protein; Osteoblast; Osteoclast; Osteopenia; Resorption; Twisted gastrulation

Indexed keywords

BONE MORPHOGENETIC PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PROTEIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; SMAD PROTEIN; TWISTED GASTRULATION 1; UNCLASSIFIED DRUG; TWISTED GASTRULATION PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MINERAL; BONE RADIOGRAPHY; CELL DIFFERENTIATION; CELL FUSION; CONTROLLED STUDY; GASTRULATION; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; OSTEOPENIA; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; BONE DEVELOPMENT; CELL CULTURE; DRUG EFFECT; GENETICS; METABOLIC BONE DISEASE; METABOLISM; PATHOLOGY; PHENOTYPE;

ANIMALS; BONE DISEASES, METABOLIC; BONE MORPHOGENETIC PROTEINS; CELL FUSION; CELLS, CULTURED; MICE; OSTEOBLASTS; OSTEOCLASTS; OSTEOGENESIS; OSTEOPROTEGERIN; PHENOTYPE; PROTEINS; RANK LIGAND; SIGNAL TRANSDUCTION; SMAD PROTEINS;

EID: 73949155251     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.090507     Document Type: Article

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