The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signalling

Nature

Volumn 405, Issue 6788, 2000, Pages 757-763

  Oelgeschläger, Michael ^a   Larrain, Juan ^a   Geissert, Douglas ^a   De Robertis, Eddy M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; METALLOPROTEINASE; PROTEIN INHIBITOR;

ARTICLE; EMBRYO; EMBRYO AXIS; EMBRYO DEVELOPMENT; GASTRULATION; GENE EXPRESSION; GENETIC CONSERVATION; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; BODY PATTERNING; BONE MORPHOGENETIC PROTEINS; CELL LINE; CONSERVED SEQUENCE; DROSOPHILA PROTEINS; EVOLUTION; GLYCOPROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEINS; SIGNAL TRANSDUCTION; XENOPUS;

EID: 0342626578     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35015500     Document Type: Article

References (50)

1. De Robertis, E. M. & Sasai, Y. A common plan for dorsoventral patterning in Bilateria. Nature 380, 37-40 (1996).
2. Harland, R. & Gerhart, J. Formation and function of Spemann's organizer. Annu. Rev. Cell. Dev. Biol. 13, 611-667 (1997).
3. Piccolo, S. et al. Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity. Cell 91, 407-416 (1997).
4. Weinmaster, G. Reprolysins and astacins. Science 279, 336-337 (1998).
5. Schulte-Merker, S., Lee, K. J., McMahon, A. P. & Hammerschmidt, M. The zebrafish organizer requires chordino. Narure 387, 862-863 (1997).
6. Kishimoto, Y, Lee, K. H., Zon, L., Hammerschmidt, M. & Schulte-Merker, S. The molecular nature of zebrafish swirl: BMP2 function is essential during early dorsoventral patterning. Development 124, 4457-4466 (1997).
7. Dick, A. et al. Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo. Development 127, 343-354 (2000).
8. Schmid, B. et al. Equivalent genetic roles for bmp7/snailhouse and bmp2b/swirl in dorsoventral pattern formation. Development 127, 957-967 (2000).
9. Hild, M, et al. The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo. Development 126, 2149-2159 (1999).
10. Connors, S. A., Trout, J., Ekker, M. & Mullins, M. C. The role of tolloid/mini fin in dorsoventral pattern formation of the zebrafish embryo. Development 126, 3119-3130 (1999).
11. Scott, I. C. et al. Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis. Dev. Biol. 213, 283-300 (1999).
12. Larrain, J. et al. BMP-binding modules in Chordin: a model for signalling regulation in the extracellular space. Development 127, 821-830 (2000).
13. Ferguson, E. L. & Anderson, K. V. Localized enhancement and repression of the activity of the TGF-beta family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo. Development 114, 583-597 (1992).
14. Ferguson, E. L. & Anderson, K. V. Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo. Cell 71, 451-461 (1992).
15. Neul, J. L. & Ferguson, E. L. Spatially restricted activation of the SAX receptor by SCW modulates DPP/TKV signaling in Drosophila dorsal-ventral patterning. Cell 95, 483-494 (1998).
16. Nguyen, M., Park, S., Marques, G. & Arora, K. Interpretation of a BMP activity gradient in Drosophila embryos depends on synergistic signaling by two type 1 receptors, SAX and TKV. Cell 95, 495-506 (1998).
17. François, V., Solloway, M., O'Neill, J. W., Emery, J. & Bier, E. Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene. Genes Dev. 8, 2602-2616 (1994).
18. Holley, S. A. et al. A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin. Nature 376, 249-253 (1995).
19. Schmidt, J., François, V., Bier, E. & Kimelman, D. Drosophila short gastrulation induces an ectopic axis in Xenopus: evidence for conserved mechanisms of dorsal-ventral patterning. Development 121, 4319-4328 (1995).
20. Zusman, S. B., Sweeton, D. & Wieschaus, E. F. Short gastrulation, a mutation causing delays in stage-specific cell shape changes during gastrulation in Drosophila melanogaster. Dev. Biol. 129, 417-427 (1988).
21. Holley, S. A. et al. The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor. Cell 86, 607-617 (1996).
22. Bier, E. A unity of opposites. Nature 398, 375-376 (1999).
23. Ashe, H. L. & Levine, M. Local inhibition and long-range enhancement of Dpp signal transduction by Sog. Nature 398, 427-431 (1999).
24. Mason, E. D., Konrad, K. D., Webb, C. D. & Marsh, J. L. Dorsal midline fate in Drosophila embryos requires twisted gastrulation, a gene encoding a secreted protein related to human connective tissue growth factor. Genes Dev. 8, 1489-1501 (1994).
25. Mason, E. D., Williams, S., Grotendorst, G. R. & Marsh, J. L. Combinatorial signaling by Twisted gastrulation and Decapentaplegic. Mech Dev. 64, 61-75 (1997).
26. Niehrs, C. & Pollet, N. Synexpression groups in eukaryotes. Nature 402, 483-487 (1999).
27. Fainsod, A., Steinbeisser, H. & De Robertis, E. M. On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo. EMBO J. 13, 5015-5025 (1994).
28. Onichtchouk, D. et al. Silencing of TGF-beta signalling by the pseudoreceptor BAMBI. Nature 401, 480-485 (1999).
29. Green, J. B. & Smith, J. C. Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate. Nature 347, 391-394 (1990).
30. Goodman, S. A. et al. BMP1-related metalloproteinases promote the development of ventral mesoderm in early Xenopus embryos. Dev. Biol. 195, 144-157 (1998).
31. Jones, C. M., Lyons, K. M., Lapan, P. M., Wright, C. V. E. & Hogan, B. L. M. DVR-4 (Bone Morphogenetic Protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction. Development 115, 639-647 (1992).
32. Hsu, D. R., Economides, A. N., Wang, X., Eimon, P. M. & Harland, R. M. The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol. Cell 1, 673-683 (1998).
33. Piccolo, S. et al. The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals. Nature 397, 707-710 (1999).
34. Rodriguez Esteban, C. et al. The novel Cer-like protein Caronte mediates the establishment of embryonic left-right asymmetry. Nature 401, 243-251 (1999).
35. Davis, S. et al. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 87, 1161-1169 (1996).
36. Flanagan, J. G. & Leder, P. The kit ligand: a cell surface molecule altered in steel mutant fibroblasts. Cell 63, 185-194 (1990).
37. Fire, A. et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811 (1998).
38. Tuschl, T., Zamore, P. D., Lehmann, R., Bartel, D. P. & Sharp, P. A. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev. 13, 3191-3197 (1999).
39. Bosher, J. M. & Labouesse, M. RNA interference: genetic wand and genetic watchdog. Nature Cell Biol. 2, 31-36 (2000).
40. Piccolo, S., Sasai, Y., Lu, B. & De Robertis, E. M. Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. Cell 86, 589-598 (1996).
41. Zhu, Y., Oganesian, A., Keene, D. R. & Sandell, L. J. Type IIA procollagen containing the cysteine-rich amino propeptide is deposited in the extracellular matrix of prechondrogenic tissue and binds to TGF-β1 and BMP-2. J. Cell Biol 144, 1069-1080 (1999).
42. Grotendorst, G. R. Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts. Cytokine Growth Factor Rev. 8, 171-179 (1997).
43. Zhang, J., Talbot, W. S. & Schier, A. F. Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation. Cell 92, 241-251 (1998).
44. Schier, A. F. & Shen, M. M. Nodal signalling in vertebrate development. Nature 403, 385-389 (2000).
45. Marques, G. et al. Production of a DPP activity gradient in the early Drosophila embryo through the opposing actions of the SOG and TLD proteins. Cell 91, 417-426 (1997).
46. Biehs, B., François, V. & Bier, E. The Drosophila short gastrulation gene prevents Dpp from autoactivating and suppressing neurogenesis in the neuroectoderm. Genes Dev. 10, 2922-2934 (1996).
47. De Robertis, E. M. in Guidebook of Homeobox Genes (ed. Duboule, D.) 11-23 (IRL, Oxford, 1994).
48. Knoll, A. H. & Carroll, S. B. Early animal evolution: emerging views from comparative biology and geology. Science 284, 2129-2137 (1999).
49. Geoffroy Saint-Hilaire, E. Considérations générales sur la vertébre. Mém. Mus. Hist. Nat. 9, 89-119 (1822).
50. Yu et al. Processing of the Drosophila Sog protein creates a novel BMP inhibitory activity. Development 127, 2143-2154 (2000).