Transport of the photodynamic therapy agent 5-aminolevulinic acid by distinct H+-coupled nutrient carriers coexpressed in the small intestine

Journal of Pharmacology and Experimental Therapeutics

Volumn 332, Issue 1, 2010, Pages 220-228

  Anderson, Catriona M H ^a   Jevons, Mark ^a   Thangaraju, Muthusamy ^b   Edwards, Noel ^a   Conlon, Nichola J ^a   Woods, Steven ^a   Ganapathy, Vadivel ^b   Thwaites, David T ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOMETHYLBENZOIC ACID; 5 HYDROXYTRYPTOPHAN; AMINO ACID TRANSPORTER; AMINOLEVULINIC ACID; COTRANSPORTER; DIPEPTIDE; H+ COUPLED AMINO ACID TRANSPORTER PAT1; H+ COUPLED AMINO ACID TRANSPORTER PEPT1; MESSENGER RNA; TRIPEPTIDE; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ARTICLE; CANCER TISSUE; COLORECTAL CANCER; CONTROLLED STUDY; DRUG SELECTIVITY; DRUG TRANSPORT; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE BRUSH BORDER; INTESTINE EPITHELIUM; ISOTOPE LABELING; NONHUMAN; OOCYTE; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMALL INTESTINE; XENOPUS;

AMINO ACID TRANSPORT SYSTEMS; AMINOLEVULINIC ACID; ANIMALS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; HUMANS; INTESTINAL MUCOSA; INTESTINE, SMALL; OOCYTES; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PRODRUGS; RNA, MESSENGER; SYMPORTERS; XENOPUS LAEVIS;

EID: 73949152544     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.159822     Document Type: Article

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