메뉴 건너뛰기




Volumn 19, Issue 11, 2005, Pages 1468-1473

Serotonin, L-tryptophan, and tryptamine are effective inhibitors of the amino acid transport system PAT1

Author keywords

Caco 2 cells; Membrane transport; Nontransported inhibitors; Proton gradient; Xenopus laevis oocytes

Indexed keywords

ALANINE; AMINO ACID TRANSPORTER; CARRIER PROTEIN; DEXTRO SERINE; GLYCINE; INDOLEPROPIONIC ACID; PROLINE; PROTEIN PAT1; SEROTONIN; TAURINE; TRYPTAMINE; TRYPTOPHAN; UNCLASSIFIED DRUG;

EID: 24644512768     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.05-3683com     Document Type: Article
Times cited : (58)

References (20)
  • 1
    • 1242295153 scopus 로고    scopus 로고
    • The SLC36 family: Proton-coupled transporters for the absorption of selected amino acids from extracellular and intracellular proteolysis
    • Boll, M., Daniel, H., and Gasnier, B. (2004) The SLC36 family: proton-coupled transporters for the absorption of selected amino acids from extracellular and intracellular proteolysis. Pfluegers Arch. 447, 776-779
    • (2004) Pfluegers Arch. , vol.447 , pp. 776-779
    • Boll, M.1    Daniel, H.2    Gasnier, B.3
  • 3
    • 0037151112 scopus 로고    scopus 로고
    • Functional characterization of two mammalian electrogenic proton-dependent amino acid cotransporters
    • Boll, M., Foltz, M., Rubio-Aliaga, I., Kottra, G., and Daniel, H. (2002) Functional characterization of two mammalian electrogenic proton-dependent amino acid cotransporters. J. Biol. Chem. 277, 22966-22973
    • (2002) J. Biol. Chem. , vol.277 , pp. 22966-22973
    • Boll, M.1    Foltz, M.2    Rubio-Aliaga, I.3    Kottra, G.4    Daniel, H.5
  • 4
    • 0037440176 scopus 로고    scopus 로고
    • Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2
    • Chen, Z., Fei, Y. J., Anderson, C. M., Wake, K. A., Miyauchi, S., Huang, W., Thwaites, D. T., and Ganapathy, V. (2003) Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2. J. Physiol. (London) 546, 349-361
    • (2003) J. Physiol. (London) , vol.546 , pp. 349-361
    • Chen, Z.1    Fei, Y.J.2    Anderson, C.M.3    Wake, K.A.4    Miyauchi, S.5    Huang, W.6    Thwaites, D.T.7    Ganapathy, V.8
  • 5
    • 0037603307 scopus 로고    scopus 로고
    • A cluster of proton/amino acid transporter genes in the human and mouse genomes
    • Boll, M., Foltz, M., Rubio-Aliaga, I., and Daniel, H. (2003) A cluster of proton/amino acid transporter genes in the human and mouse genomes. Genomics 82, 47-56
    • (2003) Genomics , vol.82 , pp. 47-56
    • Boll, M.1    Foltz, M.2    Rubio-Aliaga, I.3    Daniel, H.4
  • 8
    • 0029057614 scopus 로고
    • The role of the proton electrochemical gradient in the transepithelial absorption of amino acids by human intestinal Caco-2 cell monolayers
    • Thwaites, D. T., McEwan, G. T., and Simmons, N. L. (1995) The role of the proton electrochemical gradient in the transepithelial absorption of amino acids by human intestinal Caco-2 cell monolayers. J. Membr. Biol. 145, 245-256
    • (1995) J. Membr. Biol. , vol.145 , pp. 245-256
    • Thwaites, D.T.1    McEwan, G.T.2    Simmons, N.L.3
  • 9
    • 0028275005 scopus 로고
    • D-Cycloserine uses an active transport mechanism in the human intestinal cell line Caco 2
    • Ranaldi, G., Islam, K., and Sambuy, Y. (1994) D-Cycloserine uses an active transport mechanism in the human intestinal cell line Caco 2. Antimicrob. Agents Chemother. 38, 1239-1245
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 1239-1245
    • Ranaldi, G.1    Islam, K.2    Sambuy, Y.3
  • 11
    • 0033964573 scopus 로고    scopus 로고
    • Gamma-Aminobutyric acid (GABA) transport across human intestinal epithelial (Caco-2) cell monolayers
    • Thwaites, D. T., Basterfield, L., McCleave, P. M. J., Carter, S. M., and Simmons, N. L. (2000) Gamma-Aminobutyric acid (GABA) transport across human intestinal epithelial (Caco-2) cell monolayers. Br. J. Pharmacol 129, 457-464
    • (2000) Br. J. Pharmacol. , vol.129 , pp. 457-464
    • Thwaites, D.T.1    Basterfield, L.2    McCleave, P.M.J.3    Carter, S.M.4    Simmons, N.L.5
  • 12
    • 1642380894 scopus 로고    scopus 로고
    • Transport of pharmacologically active praline derivatives by the human proton-coupled amino acid transporter hPAT1
    • Metzner, L., Kalbitz, J., and Brandsch, M. (2004) Transport of pharmacologically active praline derivatives by the human proton-coupled amino acid transporter hPAT1. J. Pharmacol. Exp. Ther. 309, 28-35
    • (2004) J. Pharmacol. Exp. Ther. , vol.309 , pp. 28-35
    • Metzner, L.1    Kalbitz, J.2    Brandsch, M.3
  • 14
    • 9444247539 scopus 로고    scopus 로고
    • A novel bifunctionality: PAT1 and PAT2 mediate electrogenic proton/amino acid and electroneutral proton/fatty acid symport
    • Foltz, M., Boll, M., Raschka, L., Kottra, G., and Daniel, H. (2004) A novel bifunctionality: PAT1 and PAT2 mediate electrogenic proton/amino acid and electroneutral proton/fatty acid symport. FASEB J. 18, 1758-1760
    • (2004) FASEB J. , vol.18 , pp. 1758-1760
    • Foltz, M.1    Boll, M.2    Raschka, L.3    Kottra, G.4    Daniel, H.5
  • 19
    • 15744405825 scopus 로고    scopus 로고
    • Identification of a mammalian proline transporter (SIT1, SLC6A20) with characteristics of classical system IMINO
    • Takanaga, H., Mackenzie, B., Suzuki, Y., and Hediger, M. A. (2005) Identification of a mammalian proline transporter (SIT1, SLC6A20) with characteristics of classical system IMINO. J. Biol. Chem. 280, 8974-8984
    • (2005) J. Biol. Chem. , vol.280 , pp. 8974-8984
    • Takanaga, H.1    Mackenzie, B.2    Suzuki, Y.3    Hediger, M.A.4
  • 20
    • 0032134522 scopus 로고    scopus 로고
    • 5-Hydroxytryptophan: A clinically effective serotonin precursor
    • Birdsall, T. C. (1998) 5-Hydroxytryptophan: a clinically effective serotonin precursor. Altern. Med. Rev. 3, 271-280
    • (1998) Altern. Med. Rev. , vol.3 , pp. 271-280
    • Birdsall, T.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.