Substrate upregulation of the human small intestinal peptide transporter, hPepT1

Journal of Physiology

Volumn 507, Issue 3, 1998, Pages 697-706

  Walker, Dianne ^a,b   Thwaites, David T ^a   Simmons, Nicholas L ^a   Gilbert, Harry J ^a   Hirst, Barry H ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; COMPLEMENTARY DNA; GLYCYLGLUTAMINE; GLYCYLSARCOSINE; ISOLEUCINE; PEPTIDE TRANSPORTER 1; POLYADENYLATED RNA; VALINE;

AMINO ACID SUBSTITUTION; AMINO ACID TRANSPORT; ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DIET; GENETIC TRANSCRIPTION; HALF LIFE TIME; HUMAN; HUMAN CELL; INTESTINE CELL; ISOTOPE LABELING; MOLECULAR CLONING; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SMALL INTESTINE; ADAPTATION; APICAL MEMBRANE; CACO 2 CELL LINE; CONCENTRATION (PARAMETERS); MOLECULAR SIZE; PROTEIN INTAKE; RNA STABILITY; RNA TRANSCRIPTION; SEQUENCE HOMOLOGY; UPREGULATION;

ADENOCARCINOMA; AMINO ACID SUBSTITUTION; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELL LINE; CELL MEMBRANE; CLONING, MOLECULAR; COLONIC NEOPLASMS; DIPEPTIDES; GENE EXPRESSION REGULATION; HUMANS; IMMUNOBLOTTING; INTESTINE, SMALL; KINETICS; RECOMBINANT PROTEINS; RNA, MESSENGER; SYMPORTERS; TRANSCRIPTION, GENETIC;

EID: 0032521116     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1998.697bs.x     Document Type: Article

References (38)

1. ASHY, A. A., SALLEH, M. & ARDAWI, M. S. M. (1988). Glucose, glutamine and ketone-body metabolism in human enterocytes. Metabolism: Clinical and Experimental 37, 602-609.
2. BOLL, M., MARKOVICH, D., WEBER, W.-M., KORTE, H., DANIEL, H. & MURER, H. (1994). Expression cloning of a cDNA from rabbit small intestine related to proton-coupled transport of peptides, β-lactam antibiotics and ACE-inhibitors. Pflügers Archiv 429, 146-149.
3. + co-transport system in the Caco-2 human colon carcinoma cell line. Biochemical Journal 299, 253-260.
4. CHEESEMAN, C. I. & HARLEY, B. (1991). Adaptation of glucose transport across rat enterocyte basolateral membrane in response to altered dietary carbohydrate intake. Journal of Physiology 437, 563-575.
5. DIAMOND, J. M., KARASOV, W. H., CARY, C., ENDERS, D. & YUNG, R. (1984). Effect of dietary carbohydrate on monosaccharide uptake by mouse small intestine in vitro. Journal of Physiology 349, 419-440.
6. DYER, J., HOSIE, K. B. & SHIRAZI-BEECHEY, S. P. (1997). Nutrient regulation of human intestinal sugar transporter (SGLT1) expression. Gut 41, 56-59.
7. ERICKSON, R. H., GUM, J. R. G., LINDSTROM, M. M., MCKEAN, D. & KIM, Y. S. (1995). Regional expression and dietary regulation of rat small intestinal peptide and amino acid transporter mRNAs. Biochemical and Biophysical Research Communications 216, 249-257.
8. FEI, Y.-J., KANAI, Y., NUSSBERGER, S., GANAPATHY, V., LEIBACH, F. H., ROMERO, M. F., SINGH, S. K., BORON, W. F. & HEDIGER, M. A. (1994). Expression cloning of a mammalian proton-coupled oligopeptide transporter. Nature 368, 563-566.
9. FERRARIS, R. P., DIAMOND, J. & KWAN, W. W. (1988). Dietary regulation of intestinal transport of the dipeptide carnosine. American Journal of Physiology 255, G143-149.
10. FERRARIS, R. P., VILLENAS, S. A., HIRAYAMA, B. A. & DIAMOND, J. (1992). Effect of diet on glucose transporter site density along the intestinal crypt-villus axis. American Journal of Physiology 262, G1060-1068.
11. GENESTE, O., RAFFALLI, F. & LANG, M. A. (1996). Identification and characterization of a 44 kDa protein that binds specifically to the 3′-untranslated region of CYP2A5 mRNA: inducibility, subcellular distribution and possible role in mRNA stabilization. Biochemical Journal 313, 1029-1037.
12. GREEN, F., EDWARDS, Y., HAURI, H. P., POVEY, S., HO, M. W., PINTO, M. & SWALLOW, D. (1987). Isolation of a cDNA probe for a human jejunal brush-border hydrolase, sucrase-isomaltase, and assignment of the gene locus to chromosome 3. Gene 57, 101-110.
13. GRIMBLE, G. K. & SILK, D. B. A. (1989). Peptides in human nutrition. Nutrition Research Reviews 2, 87-108.
14. HIDALGO, I. T., RAUB, T. J. & BOKCHARDT, R. T. (1989). Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology 96, 736-749.
15. JALAL, F., JUMARIE, C., BAWAB, W., CORBEIL, D., MALO, C., BERTELOOT, A. & CRINE, P. (1992). Polarized distribution of neutral endopeptidase 24.11 at the cell surface of cultured human intestinal epithelial Caco-2 cells. Biochemical Journal 288, 945-951.
16. KUSUHARA, H., SHIMADA, O. & INUI, J. (1992). Effect of 25-hydroxycholesterol on cholesteryl ester formation in Caco-2 cells. Lipids 27, 478-480.
17. +/glucose cotransporter (SGLT1) is dissociated from mRNA abundance. Biochemical Journal 291, 435-440.
18. +/peptide cotransporter. Cloning, fuctional expression and chromosomal localization. Journal of Biological Chemistry 270, 6456-6463.
19. LIANG, R., FEI, Y.-J., RAMAMOORTHY, S., PRASAD, P. D., HEDIGER, M. A., GANAPATHY, V. & LEIBACH, F. H. (1994). Molecular cloning and functional expression of a peptide/proton cotransporter from human small intestine. Gastroenterology 106, A617.
20. MATTHEWS, D. M. (1991). Protein Absorption. Wiley-Liss, New York.
21. MINAMI, H., MORSE, E. L. & ADIBI, S. A. (1992). Characteristics and mechanism of glutamine-dipeptide absorption in human intestine. Gastroenterology 103, 3-11.
22. +/peptide cotransporter in the human intestinal cell line Caco-2 by cyclic AMP. Biochemical and Biophysical Research Communications 218, 461-465.
23. OKAYAMA, H. & BERG, P. (1982). High-efficiency cloning of full-length cDNA. Molecular and Cellular Biology 2, 161-170.
24. PENDE, A., TREMMEL, K. D., DEMARIA, C. T., BLAXALL, B. C., MINOBE, W. A., SHEHMAN, J. A., BISOGNANO, J. D., BRISTOW, M. R., BREWER, G. & PORT, J. (1996). Regulation of the mRNA-binding protein AUF1 by activation of the beta-adrenergic receptor signal transduction pathway. Journal of Biological Chemistry 271, 8493-8501.
25. L cells. Journal of Biological Chemistry 270, 20536-20542.
26. +/dipeptide cotransporter hPepT1 mRNA. FASEB Journal 11, A531.
27. PREISS, T., SANG, A. E., CHRZANOWSKA, L. Z. & LIGHTOWLERS, R. N. (1995). The mRNA-binding protein COLBP is glutamate dehydrogenase. FEBS Letters 367, 291-296.
28. SAITO, H. & INUI, K.-I. (1993). Dipeptide transporters in apical and basolateral membranes of the human intestinal cell line Caco-2. American Journal of Physiology 265, G289-294.
29. +/peptide cotransporter mediating absorption of β-lactam antibiotics in intestine and kidney. Journal of Pharmacology and Experimental Therapeutics 275, 1631-1637.
30. SHARP, P. A., DEBNAM, E. S. & SRAI, S. K. S. (1996). Rapid enhancement of brush border glucose uptake after exposure of rat jejunal mucosa to glucose. Gut 39, 545-550.
31. +/glucose cotransporter (SGLT1) in LLC-PK1 cells: role of protein kinase C activation and ongoing transcription. Proceedings of the National Academy of Sciences of the USA 91, 11919-11923.
32. THWAITES, D. T., BROWN, C. D. A., HIRST, B. H. & SIMMONS, N. L. (1993a). Proton-coupled dipeptide (glycylsarcosine) transport across apical and basolateral borders of human intestinal Caco-2 cell monolayers displays distinctive characteristics. Biochimica et Biophysica Acta 1151, 237-245.
33. +-coupled carriers at both apical and basal membranes. Journal of Biological Chemistry 268, 7640-7642.
34. THWAITES, D. T., MCEWAN, G. T. A., HIRST, B. H. & SIMMONS, N. L. (1993). Transepithelial dipeptide (glycylsarcosine) transport across epithelial monolayers of human Caco-2 cells is rheogenic. Pflügers Archiv 425, 178-180.
35. VAN BEERS, E. H., AL, R. H., RINGS, E. H., EINERHAND, A. W., DEKKER, J. & BULLER, H. A. (1995). Lactase and sucrase-isomaltase gene expression during Caco-2 cell differentiation. Biochemical Journal 308, 769-775.
36. WILLIAMS, D. L., SENSEL, M., MCTIGUE, M. & BINDER, R. (1993). Hormonal and developmental regulation of mRNA turnover. In Control of Messenger RNA Stability, ed. BELASCO, J. G. & BRAWERMAN, G., pp 161-197. Academic Press, New York.
37. YUASA, H., FLEISHER, D. & AMIDON, G. L. (1994). Noncompetitive inhibition of cephadrine uptake by enalapril in rabbit intestinal brush-border membrane vesicles: An enalapril specific inhibitory binding site on the peptide carrier. Journal of Pharmacology and Experimental Therapeutics 269, 1107-1111.
38. ZHANG, W., WAGNER, B. J., EHRENMAN, K., SCHAEFER, A. W., DEMARIA, C. T., CRATER, D., DE HAVEN, K., LONG, L. & BREWER, G. (1993). Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1. Molecular and Cellular Biology 13, 7652-7665.