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Volumn 95, Issue 1, 2010, Pages 27-35

Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen

Author keywords

Deletion; Erythropoiesis; Rac1 genomic sequence; Rho GTPases

Indexed keywords

RAC1 PROTEIN; RAC2 PROTEIN;

EID: 73949148016     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2009.006239     Document Type: Article
Times cited : (52)

References (37)
  • 1
    • 15244362782 scopus 로고    scopus 로고
    • Role of c-Kit and erythropoietin receptor in erythropoiesis
    • Munugalavadla V, Kapur R. Role of c-Kit and erythropoietin receptor in erythropoiesis. Crit Rev Oncol Hematol. 2005; 54(1):63-75.
    • (2005) Crit Rev Oncol Hematol , vol.54 , Issue.1 , pp. 63-75
    • Munugalavadla, V.1    Kapur, R.2
  • 3
    • 50949089311 scopus 로고    scopus 로고
    • Erythroblastic islands: Niches for erythropoiesis
    • Chasis JA, Mohandas N. Erythroblastic islands: niches for erythropoiesis. Blood. 2008;112(3):470-8.
    • (2008) Blood , vol.112 , Issue.3 , pp. 470-478
    • Chasis, J.A.1    Mohandas, N.2
  • 4
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • Akashi K, Traver D, Miyamoto T, Weissman IL. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature. 2000;404(6774): 193-7.
    • (2000) Nature , vol.404 , Issue.6774 , pp. 193-197
    • Akashi, K.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4
  • 5
    • 34250214880 scopus 로고    scopus 로고
    • Myeloid lineage commitment from the hematopoietic stem cell
    • Iwasaki H, Akashi K. Myeloid lineage commitment from the hematopoietic stem cell. Immunity. 2007;26(6):726-40.
    • (2007) Immunity , vol.26 , Issue.6 , pp. 726-740
    • Iwasaki, H.1    Akashi, K.2
  • 6
    • 0016794940 scopus 로고
    • Studies of murine erythroid cell development. Synthesis of heme and hemoglobin
    • Glass J, Lavidor LM, Robinson SH. Studies of murine erythroid cell development. Synthesis of heme and hemoglobin. J Cell Biol. 1975;65(2):298-308.
    • (1975) J Cell Biol , vol.65 , Issue.2 , pp. 298-308
    • Glass, J.1    Lavidor, L.M.2    Robinson, S.H.3
  • 7
    • 0942263632 scopus 로고    scopus 로고
    • The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage
    • Kina T, Ikuta K, Takayama E, Wada K, Majumdar AS, Weissman IL, et al. The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage. Br J Haematol. 2000;109(2):280-7.
    • (2000) Br J Haematol , vol.109 , Issue.2 , pp. 280-287
    • Kina, T.1    Ikuta, K.2    Takayama, E.3    Wada, K.4    Majumdar, A.S.5    Weissman, I.L.6
  • 8
    • 0019975069 scopus 로고
    • Changes in cell surface antigen expression during hemopoietic differentiation
    • Sieff C, Bicknell D, Caine G, Robinson J, Lam G, Greaves MF. Changes in cell surface antigen expression during hemopoietic differentiation. Blood. 1982;60(3):703-13.
    • (1982) Blood , vol.60 , Issue.3 , pp. 703-713
    • Sieff, C.1    Bicknell, D.2    Caine, G.3    Robinson, J.4    Lam, G.5    Greaves, M.F.6
  • 9
    • 0023158748 scopus 로고
    • Flow cytometric analysis of human bone marrow: I. Normal erythroid development
    • Loken MR, Shah VO, Dattilio KL, Civin CI. Flow cytometric analysis of human bone marrow: I. Normal erythroid development. Blood. 1987;69(1):255-63.
    • (1987) Blood , vol.69 , Issue.1 , pp. 255-263
    • Loken, M.R.1    Shah, V.O.2    Dattilio, K.L.3    Civin, C.I.4
  • 10
    • 0035760889 scopus 로고    scopus 로고
    • Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts
    • Socolovsky M, Nam H, Fleming MD, Haase VH, Brugnara C, Lodish HF. Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts. Blood 2001;98(12):3261-73.
    • (2001) Blood , vol.98 , Issue.12 , pp. 3261-3273
    • Socolovsky, M.1    Nam, H.2    Fleming, M.D.3    Haase, V.H.4    Brugnara, C.5    Lodish, H.F.6
  • 11
    • 46149111430 scopus 로고    scopus 로고
    • Multispectral imaging of hematopoietic cells: Where flow meets morphology
    • McGrath KE, Bushnell TP, Palis J. Multispectral imaging of hematopoietic cells: where flow meets morphology. J Immunol Methods. 2008;336(2):91-7.
    • (2008) J Immunol Methods , vol.336 , Issue.2 , pp. 91-97
    • McGrath, K.E.1    Bushnell, T.P.2    Palis, J.3
  • 12
    • 15944394718 scopus 로고    scopus 로고
    • BMP4 and Madh5 regulate the erythroid response to acute anemia
    • Lenox LE, Perry JM, Paulson RF. BMP4 and Madh5 regulate the erythroid response to acute anemia. Blood. 2005;105(7):2741-8.
    • (2005) Blood , vol.105 , Issue.7 , pp. 2741-2748
    • Lenox, L.E.1    Perry, J.M.2    Paulson, R.F.3
  • 13
    • 34248335074 scopus 로고    scopus 로고
    • BMP4, SCF, and hypoxia cooperatively regulate the expansion of murine stress erythroid progenitors
    • Perry JM, Harandi OF, Paulson RF. BMP4, SCF, and hypoxia cooperatively regulate the expansion of murine stress erythroid progenitors. Blood. 2007;109(10):4494-502.
    • (2007) Blood , vol.109 , Issue.10 , pp. 4494-4502
    • Perry, J.M.1    Harandi, O.F.2    Paulson, R.F.3
  • 14
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville S, Hall A. Rho GTPases in cell biology. Nature. 2002;420(6916):629-35.
    • (2002) Nature , vol.420 , Issue.6916 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 16
    • 0030824832 scopus 로고    scopus 로고
    • Characterization of RAC3, a novel member of the Rho family
    • Haataja L, Groffen J, Heisterkamp N. Characterization of RAC3, a novel member of the Rho family. J Biol Chem. 1997; 272(33):20384-8.
    • (1997) J Biol Chem , vol.272 , Issue.33 , pp. 20384-20388
    • Haataja, L.1    Groffen, J.2    Heisterkamp, N.3
  • 17
    • 33845243747 scopus 로고    scopus 로고
    • Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton
    • Kalfa TA, Pushkaran S, Mohandas N, Hartwig JH, Fowler VM, Johnson JF, et al. Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton. Blood 2006;108(12):3637-45.
    • (2006) Blood , vol.108 , Issue.12 , pp. 3637-3645
    • Kalfa, T.A.1    Pushkaran, S.2    Mohandas, N.3    Hartwig, J.H.4    Fowler, V.M.5    Johnson, J.F.6
  • 18
    • 23844542698 scopus 로고    scopus 로고
    • Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization
    • Cancelas JA, Lee AW, Prabhakar R, Stringer KF, Zheng Y, Williams DA. Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization. Nat Med. 2005;11(8):886-91.
    • (2005) Nat Med , vol.11 , Issue.8 , pp. 886-891
    • Cancelas, J.A.1    Lee, A.W.2    Prabhakar, R.3    Stringer, K.F.4    Zheng, Y.5    Williams, D.A.6
  • 19
    • 0026767488 scopus 로고
    • Steel factor stimulates the tyrosine phospho rylation of the proto-oncogene product, p95vav, in human hemopoietic cells
    • Alai M, Mui AL, Cutler RL, Bustelo XR, Barbacid M, Krystal G. Steel factor stimulates the tyrosine phospho rylation of the proto-oncogene product, p95vav, in human hemopoietic cells. J Biol Chem. 1992; 267(25):18021-5.
    • (1992) J Biol Chem , vol.267 , Issue.25 , pp. 18021-18025
    • Alai, M.1    Mui, A.L.2    Cutler, R.L.3    Bustelo, X.R.4    Barbacid, M.5    Krystal, G.6
  • 20
    • 0031033292 scopus 로고    scopus 로고
    • Phosphotyrosinedependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
    • Crespo P, Schuebel KE, Ostrom AA, Gutkind JS, Bustelo XR. Phosphotyrosinedependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product. Nature. 1997;385(6612):169-72.
    • (1997) Nature , vol.385 , Issue.6612 , pp. 169-172
    • Crespo, P.1    Schuebel, K.E.2    Ostrom, A.A.3    Gutkind, J.S.4    Bustelo, X.R.5
  • 21
    • 0035377208 scopus 로고    scopus 로고
    • Establishment of normal, terminally differentiating mouse erythroid progenitors: Molecular characterization by cDNA arrays
    • Dolznig H, Boulme F, Stangl K, Deiner EM, Mikulits W, Beug H, et al. Establishment of normal, terminally differentiating mouse erythroid progenitors: molecular characterization by cDNA arrays. Faseb J. 2001; 15(8):1442-4.
    • (2001) Faseb J , vol.15 , Issue.8 , pp. 1442-1444
    • Dolznig, H.1    Boulme, F.2    Stangl, K.3    Deiner, E.M.4    Mikulits, W.5    Beug, H.6
  • 22
    • 22544452677 scopus 로고    scopus 로고
    • Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation
    • Munugalavadla V, Dore LC, Tan BL, Hong L, Vishnu M, Weiss MJ, et al. Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation. Mol Cell Biol. 2005; 25(15):6747-59.
    • (2005) Mol Cell Biol , vol.25 , Issue.15 , pp. 6747-6759
    • Munugalavadla, V.1    Dore, L.C.2    Tan, B.L.3    Hong, L.4    Vishnu, M.5    Weiss, M.J.6
  • 23
    • 30144446099 scopus 로고    scopus 로고
    • Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment
    • Wang L, Yang L, Filippi MD, Williams DA, Zheng Y. Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment. Blood. 2006;107(1):98-105.
    • (2006) Blood , vol.107 , Issue.1 , pp. 98-105
    • Wang, L.1    Yang, L.2    Filippi, M.D.3    Williams, D.A.4    Zheng, Y.5
  • 24
    • 37049019099 scopus 로고    scopus 로고
    • Cdc42 critically regulates the balance between myelopoiesis and erythropoiesis
    • Yang L, Wang L, Kalfa T, Cancelas JA, Shang X, Pushkaran S, et al. Cdc42 critically regulates the balance between myelopoiesis and erythropoiesis. Blood. 2007;110(12):3853-61.
    • (2007) Blood , vol.110 , Issue.12 , pp. 3853-3861
    • Yang, L.1    Wang, L.2    Kalfa, T.3    Cancelas, J.A.4    Shang, X.5    Pushkaran, S.6
  • 25
    • 2442664118 scopus 로고    scopus 로고
    • Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
    • Gao Y, Dickerson JB, Guo F, Zheng J, Zheng Y. Rational design and characterization of a Rac GTPase-specific small molecule inhibitor. Proc Natl Acad Sci USA. 2004; 101(20):7618-23.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.20 , pp. 7618-7623
    • Gao, Y.1    Dickerson, J.B.2    Guo, F.3    Zheng, J.4    Zheng, Y.5
  • 26
    • 33745634866 scopus 로고    scopus 로고
    • Suppression of Fas-FasL coexpression by erythropoietin mediates erythroblast expansion during the erythropoietic stress response in vivo
    • Liu Y, Pop R, Sadegh C, Brugnara C, Haase VH, Socolovsky M. Suppression of Fas-FasL coexpression by erythropoietin mediates erythroblast expansion during the erythropoietic stress response in vivo. Blood. 2006;108(1):123-33.
    • (2006) Blood , vol.108 , Issue.1 , pp. 123-133
    • Liu, Y.1    Pop, R.2    Sadegh, C.3    Brugnara, C.4    Haase, V.H.5    Socolovsky, M.6
  • 27
    • 33748684364 scopus 로고    scopus 로고
    • Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo
    • Braun BS, Archard JA, Van Ziffle JA, Tuveson DA, Jacks TE, Shannon K. Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo. Blood. 2006;108(6):2041-4.
    • (2006) Blood , vol.108 , Issue.6 , pp. 2041-2044
    • Braun, B.S.1    Archard, J.A.2    Van Ziffle, J.A.3    Tuveson, D.A.4    Jacks, T.E.5    Shannon, K.6
  • 28
    • 38949097546 scopus 로고    scopus 로고
    • A heme export protein is required for red blood cell differentiation and iron homeostasis
    • Keel SB, Doty RT, Yang Z, Quigley JG, Chen J, Knoblaugh S, et al. A heme export protein is required for red blood cell differentiation and iron homeostasis. Science. 2008;319(5864):825-8.
    • (2008) Science , vol.319 , Issue.5864 , pp. 825-828
    • Keel, S.B.1    Doty, R.T.2    Yang, Z.3    Quigley, J.G.4    Chen, J.5    Knoblaugh, S.6
  • 29
    • 34547699517 scopus 로고    scopus 로고
    • Foxo3 is required for the regulation of oxidative stress in erythropoiesis
    • Marinkovic D, Zhang X, Yalcin S, Luciano JP, Brugnara C, Huber T, et al. Foxo3 is required for the regulation of oxidative stress in erythropoiesis. J Clin Invest. 2007;117(8):2133-44.
    • (2007) J Clin Invest , vol.117 , Issue.8 , pp. 2133-2144
    • Marinkovic, D.1    Zhang, X.2    Yalcin, S.3    Luciano, J.P.4    Brugnara, C.5    Huber, T.6
  • 30
    • 0020354532 scopus 로고
    • Transferrin receptors and iron uptake during erythroid cell development
    • Iacopetta BJ, Morgan EH, Yeoh GC. Transferrin receptors and iron uptake during erythroid cell development. Biochim Biophys Acta. 1982;687(2):204-10.
    • (1982) Biochim Biophys Acta , vol.687 , Issue.2 , pp. 204-210
    • Iacopetta, B.J.1    Morgan, E.H.2    Yeoh, G.C.3
  • 32
    • 0025888369 scopus 로고
    • Human burst-forming units-erythroid need direct interaction with stem cell factor for further development
    • Dai CH, Krantz SB, Zsebo KM. Human burst-forming units-erythroid need direct interaction with stem cell factor for further development. Blood. 1991;78(10):2493-7.
    • (1991) Blood , vol.78 , Issue.10 , pp. 2493-2497
    • Dai, C.H.1    Krantz, S.B.2    Zsebo, K.M.3
  • 33
    • 0032728906 scopus 로고    scopus 로고
    • Cellular and molecular regulation of an erythropoietic inductive microenvironment (EIM)
    • Obinata M, Yanai N. Cellular and molecular regulation of an erythropoietic inductive microenvironment (EIM). Cell Struct Funct. 1999;24(4):171-9.
    • (1999) Cell Struct Funct , vol.24 , Issue.4 , pp. 171-179
    • Obinata, M.1    Yanai, N.2
  • 34
    • 0029957757 scopus 로고    scopus 로고
    • Interaction of stem cell factor and its receptor c-kit mediates lodgment and acute expansion of hematopoietic cells in the murine spleen
    • Broudy VC, Lin NL, Priestley GV, Nocka K, Wolf NS. Interaction of stem cell factor and its receptor c-kit mediates lodgment and acute expansion of hematopoietic cells in the murine spleen. Blood. 1996; 88(1):75-81.
    • (1996) Blood , vol.88 , Issue.1 , pp. 75-81
    • Broudy, V.C.1    Lin, N.L.2    Priestley, G.V.3    Nocka, K.4    Wolf, N.S.5
  • 35
    • 3142683813 scopus 로고    scopus 로고
    • Apoptotic mechanisms in the control of erythropoiesis
    • Testa U. Apoptotic mechanisms in the control of erythropoiesis. Leukemia. 2004; 18(7):1176-99.
    • (2004) Leukemia , vol.18 , Issue.7 , pp. 1176-1199
    • Testa, U.1
  • 36
    • 0017103290 scopus 로고
    • Erthropoietic precursors in mice with phenylhydrazine-induced anemia
    • Hara H, Ogawa M. Erthropoietic precursors in mice with phenylhydrazine-induced anemia. Am J Hematol. 1976;1(4):453-8.
    • (1976) Am J Hematol , vol.1 , Issue.4 , pp. 453-458
    • Hara, H.1    Ogawa, M.2
  • 37
    • 0025082258 scopus 로고
    • Migration of stem cells and progenitors between marrow and spleen following thiamphenicol treatment of mice
    • Goris H, Bungart B, Loeffler M, Schmitz S, Nijhof W. Migration of stem cells and progenitors between marrow and spleen following thiamphenicol treatment of mice. Exp Hematol. 1990;18(5):400-7.
    • (1990) Exp Hematol , vol.18 , Issue.5 , pp. 400-407
    • Goris, H.1    Bungart, B.2    Loeffler, M.3    Schmitz, S.4    Nijhof, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.