Antigen-specific induction of osteopontin contributes to the chronification of allergic contact dermatitis

American Journal of Pathology

Volumn 176, Issue 1, 2010, Pages 246-258

  Seier, Anne M ^a   Renkl, Andreas C ^a   Schulz, Guido ^a   Uebele, Tanja ^b   Sindrilaru, Anca ^a   Iben, Sebastian ^a   Liaw, Lucy ^b   Kon, Shigeyuki ^c   Uede, Toshimitsu ^c   Weiss, Johannes M ^a  

^a UNIVERSITY OF ULM   (Germany)

^b Maine Medical Center Research Institute   (United States)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 4; NICKEL; OSTEOPONTIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONICITY; CLINICAL ARTICLE; CONTACT ALLERGY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DOWN REGULATION; EFFECTOR CELL; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATORY CELL; KERATINOCYTE; LYMPHOCYTE CLONE; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SKIN ALLERGY; STIMULATION; T LYMPHOCYTE;

EID: 73949098020     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.090488     Document Type: Article

References (62)

1. Diepgen TL, Coenraads PJ: The epidemiology of occupational contact dermatitis. Int Arch Occup Environ Health 1999, 72:496-506
2. Kimber I, Dearman RJ: Allergic contact dermatitis: the cellular effectors. Contact Dermatitis 2002, 46:1-5
3. Cavani A, Girolomoni G: Immune mechanisms in allergic contact dermatitis. Georgetown, TX, Landes Bioscience, 2005, pp 1-14
4. Hogan DJ, Dannaker CJ, Maibach HI: The prognosis of contact dermatitis. J Am Acad Dermatol 1990, 23:300-307
5. Thyssen JP, Johansen JD, Menne T: Contact allergy epidemics and their controls. Contact Dermatitis 2007, 56:185-195
6. Frosch PJ, Menne T, Lepoittevin JP: Contact dermatitis. Berlin, Springer, 2007, pp 135-150
7. Romani N, Ebner S, Tripp CH, Flacher V, Koch F, Stoitzner P: Epidermal Langerhans cells - changing views on their function in vivo. Immunol Lett 2006, 106:119-125
8. Kaplan DH, Jenison MC, Saeland S, Shlomchik WD, Shlomchik MJ: Epidermal Langerhans cell-deficient mice develop enhanced contact hypersensitivity. Immunity 2005, 23:611-620
9. Kissenpfennig A, Henri S, Dubois B, Laplace-Builhe C, Perrin P, Romani N, Tripp CH, Douillard P, Leserman L, Kaiserlian D, Saeland S, Davoust J, Malissen B: Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity 2005, 22:643-654
10. Cavani A, Albanesi C, Traidl C, Sebastiani S, Girolomoni G: Effector and regulatory T cells in allergic contact dermatitis. Trends Immunol 2001, 22:118-120
11. Martin SF, Jakob T: From innate to adaptive immune responses in contact hypersensitivity. Curr Opin Allergy Clin Immunol 2008, 8:289-293
12. Pichler BJ, Kneilling M, Haubner R, Braumuller H, Schwaiger M, Rocken M, Weber WA: Imaging of delayed-type hypersensitivity reaction by PET and 18F-galacto-RGD. J Nucl Med 2005, 46:184-189
13. O'Regan AW, Nau GJ, Chupp GL, Berman JS: Osteopontin (Eta-I) in cell mediated immunity: teaching an old dog new tricks. Immunol Today 2000, 21:475-478
14. Denhardt DT, Noda M, O'Regan AW, Pavlin D, Berman JS: Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival. J Clin Invest 2001, 107:1055-1061
15. Wang KX, Denhardt DT: Osteopontin: role in immune regulation and stress responses. Cytokine Growth Factor Rev 2008, 19:333-345
16. Buback F, Renkl AC, Schulz G, Weiss JM: Osteopontin and the skin: -Multiple emerging roles in cutaneous biology and pathology. Exp Dermatol 2009, 18:750-759
17. Cantor H, Shinohara ML: Regulation of T helper cell lineage development by osteopontin: the inside story. Nat Rev Immunol 2009, 9:137-141
18. Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS, Glimcher LH, Cantor H: Osteopontin expression is essential for interferon-α production by plasmacytoid dendritic cells. Nat Immunol 2006, 7:498-506
19. Shinohara ML, Kim JH, Garcia VA, Cantor H: Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity 2008, 29: 68-78
20. Shinohara ML, Kim HJ, Kim JH, Garcia VA, Cantor H: Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells. Proc Natl Acad Sci USA 2008, 105:7235-7239
21. Xanthou G, Alissafi T, Semitekolou M, Simoes DC, Economidou E, Gaga M, Lambrecht BN, Lloyd CM, Panoutsakopoulou V: Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets. Nat Med 2007, 13:570-578
22. Weiss JM, Renkl AC, Maier CS, Kimmig M, Liaw L, Ahrens T, Kon S, Maeda M, Hotta H, Uede T, Simon JC: Osteopontin is involved in the initiation of cutaneous contact hypersensitivity by inducing Langerhans and dendritic cell migration to lymph nodes. J Exp Med 2001, 194:1219-1229
23. + T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis. J Immunol 2008, 181:7480-7488
24. Shinohara ML, Jansson M, Hwang ES, Werneck MB, Glimcher LH, Cantor H: T-bet-dependent expression of osteopontin contributes to T cell polarization. Proc Natl Acad Sci USA 2005, 102:17101-17106
25. Wong CK, Lit LC, Tam LS, Li EK, Lam CW: Elevation of plasma osteopontin concentration is correlated with disease activity in patients with systemic lupus erythematosus. Rheumatology (Oxford) 2005, 44:602-606
26. Comabella M, Pericot I, Goertsches R, Nos C, Castillo M, Blas NJ, Rio J, Montalban X: Plasma osteopontin levels in multiple sclerosis. J Neuroimmunol 2005, 158:231-239
27. Xu G, Nie H, Li N, Zheng W, Zhang D, Feng G, Ni L, Xu R, Hong J, Zhang JZ: Role of osteopontin in amplification and perpetuation of rheumatoid synovitis. J Clin Invest 2005, 115:1060-1067
28. Sato T, Nakai T, Tamura N, Okamoto S, Matsuoka K, Sakuraba A, Fukushima T, Uede T, Hibi T: Osteopontin/Eta-1 up-regulated in Crohn's disease regulates the Th1 immune response. Gut 2005, 54:1254-1262
29. Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L: The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science 2001, 294:1731-1735
30. Kitamura M, Iwabuchi K, Kitaichi N, Kon S, Kitamei H, Namba K, Yoshida K, Denhardt DT, Rittling SR, Ohno S, Uede T, Onoe K: Osteopontin aggravates experimental autoimmune uveoretinitis in mice. J Immunol 2007, 178:6567-6572
31. Jansson M, Panoutsakopoulou V, Baker J, Klein L, Cantor H: Cutting edge: attenuated experimental autoimmune encephalomyelitis in eta-1/osteopontin- deficient mice. J Immunol 2002, 168:2096-2099
32. Tanaka K, Morimoto J, Kon S, Kimura C, Inobe M, Diao H, Hirschfeld G, Weiss JM, Uede T: Effect of osteopontin alleles on β-glucan-induced granuloma formation in the mouse liver. Am J Pathol 2004, 164:567-575
33. Renkl AC, Wussler J, Eggers T, Maier CS, Ahrens T, Martin S, Liaw L, Kon S, Uede T, Hirschfeld G, Simon JC, Weiss JM: Th1 cytokine-like properties of osteopontin on T cells, macrophages, and dendritic cells in type 1 immune responses. Allergy Clin Immunol Int 2004, Supp 1:97-102
34. Hur EM, Youssef S, Haws ME, Zhang SY, Sobel RA, Steinman L: Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nat Immunol 2007, 8:74-83
35. Sodek J, Batista Da Silva AP, Zohar R: Osteopontin and mucosal protection. J Dent Res 2006, 85:404-415
36. Renkl AC, Wussler J, Ahrens T, Thoma K, Kon S, Uede T, Martin S, Simon JC, Weiss JM: Osteopontin functionally activates dendritic cells and induces their differentiation towards a Th-1 polarizing phenotype. Blood 2005, 106:946-955
37. Schulz G, Renkl AC, Seier A, Liaw L, Weiss JM: Regulated osteopontin expression by dendritic cells decisively affects their migratory capacity. J Invest Dermatol 2008, 128:2541-2544
38. Kon S, Yokosaki Y, Maeda M, Segawa T, Horikoshi Y, Tsukagoshi H, Rashid MM, Morimoto J, Inobe M, Shijubo N, Chambers AF, Uede T: Mapping of functional epitopes of osteopontin by monoclonal antibodies raised against defined internal sequences. J Cell Biochem 2002, 84:420-432
39. Weiss JM, Renkl AC, Denfeld RW, de Roche R, Spitzlei M, Schöpf E, Simon JC: Low-dose UVB radiation perturbs the functional expression of B7.1 and B7.2 co-stimulatory molecules on human Langerhans cells. Eur J Immunol 1995, 25:2858-2862
40. + cytotoxic T cells from allergic donors. J Invest Dermatol 1998, 111:360-366
41. Denfeld RW, Hollenbaugh D, Fehrenbach A, Weiss JM, von Leoprechting A, Mai B, Voith U, Schöpf E, Aruffo A, Simon JC: CD40 is functionally expressed on human keratinocytes. Eur J Immunol 1996, 26:2329-2334
42. Liaw L, Birk DE, Ballas CB, Whitsitt JS, Davidson JM, Hogan BL: Altered wound healing in mice lacking a functional osteopontin gene (spp1). J Clin Invest 1998, 101:1468-1478
43. Weiss JM, Sleeman J, Renkl AC, Dittmar HC, Termeer CT, Taxis S, Howells N, Hofmann M, Köhler G, Schöpf E, Ponta H, Herrlich P, Simon JC: An essential role for CD44 variant isoforms in epidermal Langerhans cell and blood dendritic cell function. J Cell Biol 1997, 137:1137-1147
44. -ΔΔCT method. Methods 2001, 25:402-408
45. Young MF, Kerr JM, Termine JD, Wewer UM, Wang MG, McBride OW, Fisher LW: cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN). Genomics 1990, 7:491-502
46. Ahrens T, Pertz O, Haussinger D, Fauser C, Schulthess T, Engel J: Analysis of heterophilic and homophilic interactions of cadherins using the c-Jun/c-Fos dimerization domains. J Biol Chem 2002, 277:19455-19460
47. Chiocchetti A, Indelicato M, Bensi T, Mesturini R, Giordano M, Sametti S, Castelli L, Bottarel F, Mazzarino MC, Garbarini L, Giacopelli F, Valesini G, Santoro C, Dianzani I, Ramenghi U, Dianzani U: High levels of osteopontin associated with polymorphisms in its gene are a risk factor for development of autoimmunity/lymphoproliferation. Blood 2004, 103:1376-1382
48. Patarca R, Freeman GJ, Singh RP, Wei FY, Durfee T, Blattner F, Regnier DC, Kozak CA, Mock BA, Morse HC3: Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene: definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection. J Exp Med 1989, 170:145-161
49. Moulon C, Vollmer J, Weltzien HU: Characterization of processing requirements and metal cross-reactivities in T cell clones from patients with allergic contact dermatitis to nickel. Eur J Immunol 1995, 25:3308-3315
50. Albanesi C, Cavani A, Scarponi C, Girolomoni G: Multiple roles of keratinocytes in allergic contact dermatitis: immune mechanisms in allergic contact dermatitis. Edited by A Cavani and G Girolomoni. Georgetown, TX, Landes Bioscience, 2005, pp 104-112
51. Ashkar S, Weber GF, Panoutsakopoulou V, Sanchirico ME, Jansson M, Zawaideh S, Rittling SR, Denhardt DT, Glimcher MJ, Cantor H: Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science 2000, 287:860-864
52. O'Regan AW, Chupp GL, Lowry JA, Goetschkes M, Mulligan N, Berman JS: Osteopontin is associated with T cells in sarcoid granulomas and has T cell adhesive and cytokine-like properties in vitro. J Immunol 1999, 162:1024-1031
53. Bruemmer D, Collins AR, Noh G, Wang W, Territo M, Arias-Magallona S, Fishbein MC, Blaschke F, Kintscher U, Graf K, Law RE, Hsueh WA: Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice. J Clin Invest 2003, 112:1318-1331
54. Konno S, Golden DB, Schroeder J, Hamilton RG, Lichtenstein LM, Huang SK: Level of osteopontin is increased after bee venom immunotherapy. J Allergy Clin Immunol 2005, 115:1317-1318
55. Albanesi C, Scarponi C, Giustizieri ML, Girolomoni G: Keratinocytes in inflammatory skin diseases. Curr Drug Targets Inflamm Allergy 2005, 4:329-334
56. Zohar R, Suzuki N, Suzuki K, Arora P, Glogauer M, McCulloch CA, Sodek J: Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration. J Cell Physiol 2000, 184:118-130
57. Burdo TH, Wood MR, Fox HS: Osteopontin prevents monocyte recirculation and apoptosis. J Leukoc Biol 2007, 81:1504-1511
58. Lee JL, Wang MJ, Sudhir PR, Chen GD, Chi CW, Chen JY: Osteopontin promotes integrin activation through outside-in and inside-out mechanisms: OPN-CD44V interaction enhances survival in gastrointestinal cancer cells. Cancer Res 2007, 67:2089-2097
59. 3-induced endothelial cell survival. J Vasc Res 2006, 43:422-436
60. Cook AC, Tuck AB, McCarthy S, Turner JG, Irby RB, Bloom GC, Yeatman TJ, Chambers AF: Osteopontin induces multiple changes in gene expression that reflect the six "hallmarks of cancer" in a model of breast cancer progression. Mol Carcinog 2005, 43:225-236
61. Ohshima S, Yamaguchi N, Nishioka K, Mima T, Ishii T, Umeshita-Sasai M, Kobayashi H, Shimizu M, Katada Y, Wakitani S, Murata N, Nomura S, Matsuno H, Katayama R, Kon S, Inobe M, Uede T, Kawase I, Saeki Y: Enhanced local production of osteopontin in rheumatoid joints. J Rheumatol 2002, 29:2061-2067
62. Diao H, Kon S, Iwabuchi K, Kimura C, Morimoto J, Ito D, Segawa T, Maeda M, Hamuro J, Nakayama T, Taniguchi M, Yagita H, Van Kaer L, Onoe K, Denhardt D, Rittling S, Uede T: Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases. Immunity 2004, 21:539-550