Dominance and gene dosage balance in health and disease: Why levels matter!

Journal of Pathology

Volumn 220, Issue 2, 2010, Pages 174-185

  Veitia, Reiner A ^a,b   Birchler, James A ^c  

^a INSTITUT JACQUES MONOD   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c UNIVERSITY OF MISSOURI   (United States)

Author keywords

Cooperativity; Haploinsufficiency; Macromolecular complexes; Transcriptional synergy

Indexed keywords

ALLELE; CANCER GENETICS; DOMINANCE BEHAVIOR; GENE DOSAGE; GENE EXPRESSION; GENE LOCUS; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; MACROMOLECULE; PHENOTYPE; PRIORITY JOURNAL; REVIEW; SOMATIC MUTATION;

ANIMALS; GENE DOSAGE; GENES, DOMINANT; GENETIC DISEASES, INBORN; HAPLOTYPES; HUMANS; MACROMOLECULAR SUBSTANCES; MUTATION; NEOPLASMS; TRANSCRIPTION, GENETIC;

EID: 73949089947     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2623     Document Type: Review

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