-
1
-
-
0034046086
-
Gene regulatory networks generating the phenomena of additivity, dominance and epistasis
-
Omholt S.W., et al. Gene regulatory networks generating the phenomena of additivity, dominance and epistasis. Genetics 155 (2000) 969-980
-
(2000)
Genetics
, vol.155
, pp. 969-980
-
-
Omholt, S.W.1
-
2
-
-
0035875867
-
Dosage-dependent gene regulation in multicellular eukaryotes: implications for dosage compensation, aneuploid syndromes, and quantitative traits
-
Birchler J.A., et al. Dosage-dependent gene regulation in multicellular eukaryotes: implications for dosage compensation, aneuploid syndromes, and quantitative traits. Dev. Biol. 234 (2001) 275-288
-
(2001)
Dev. Biol.
, vol.234
, pp. 275-288
-
-
Birchler, J.A.1
-
3
-
-
0036008552
-
Exploring the etiology of haploinsufficiency
-
Veitia R.A. Exploring the etiology of haploinsufficiency. Bioessays 24 (2002) 175-184
-
(2002)
Bioessays
, vol.24
, pp. 175-184
-
-
Veitia, R.A.1
-
4
-
-
0037210828
-
Nonlinear effects in macromolecular assembly and dosage sensitivity
-
Veitia R.A. Nonlinear effects in macromolecular assembly and dosage sensitivity. J. Theor. Biol. 220 (2003) 19-25
-
(2003)
J. Theor. Biol.
, vol.220
, pp. 19-25
-
-
Veitia, R.A.1
-
5
-
-
0038157152
-
Dosage sensitivity and the evolution of gene families in yeast
-
Papp B., et al. Dosage sensitivity and the evolution of gene families in yeast. Nature 424 (2003) 194-197
-
(2003)
Nature
, vol.424
, pp. 194-197
-
-
Papp, B.1
-
6
-
-
0036141992
-
Relating whole-genome expression data with protein-protein interactions
-
Jansen R., et al. Relating whole-genome expression data with protein-protein interactions. Genome Res. 12 (2002) 37-46
-
(2002)
Genome Res.
, vol.12
, pp. 37-46
-
-
Jansen, R.1
-
7
-
-
38949188039
-
Protein coevolution and isoexpression in yeast macromolecular complexes
-
Ettwiller L., and Veitia R.A. Protein coevolution and isoexpression in yeast macromolecular complexes. Comp. Funct. Genom. 2007 (2007) 57721
-
(2007)
Comp. Funct. Genom.
, vol.2007
, pp. 57721
-
-
Ettwiller, L.1
Veitia, R.A.2
-
8
-
-
0031731487
-
Genomic disorders: structural features of the genome can lead to DNA rearrangements and human disease traits
-
Lupski J.R. Genomic disorders: structural features of the genome can lead to DNA rearrangements and human disease traits. Trends Genet. 14 (1998) 417-422
-
(1998)
Trends Genet.
, vol.14
, pp. 417-422
-
-
Lupski, J.R.1
-
9
-
-
13144307116
-
Gene dosage balance: deletions, duplications and dominance
-
Veitia R.A. Gene dosage balance: deletions, duplications and dominance. Trends Genet. 21 (2005) 33-35
-
(2005)
Trends Genet.
, vol.21
, pp. 33-35
-
-
Veitia, R.A.1
-
10
-
-
0346734130
-
Organismal complexity, protein complexity, and gene duplicability
-
Yang J., et al. Organismal complexity, protein complexity, and gene duplicability. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 15661-15665
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 15661-15665
-
-
Yang, J.1
-
11
-
-
3142732892
-
Functional divergence of duplicated genes formed by polyploidy during Arabidopsis evolution
-
Blanc G., and Wolfe K.H. Functional divergence of duplicated genes formed by polyploidy during Arabidopsis evolution. Plant Cell 16 (2004) 1679-1691
-
(2004)
Plant Cell
, vol.16
, pp. 1679-1691
-
-
Blanc, G.1
Wolfe, K.H.2
-
12
-
-
17244368487
-
Modeling gene and genome duplications in eukaryotes
-
Maere S., et al. Modeling gene and genome duplications in eukaryotes. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 5454-5459
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 5454-5459
-
-
Maere, S.1
-
13
-
-
33745610025
-
Gene-balanced duplications, like tetraploid, provide predictable drive to increase morphological complexity
-
Freeling M., and Thomas B.C. Gene-balanced duplications, like tetraploid, provide predictable drive to increase morphological complexity. Genome Res. 16 (2006) 805-814
-
(2006)
Genome Res.
, vol.16
, pp. 805-814
-
-
Freeling, M.1
Thomas, B.C.2
-
14
-
-
33750858684
-
Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia
-
Aury J.-M., et al. Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia. Nature 444 (2006) 171-178
-
(2006)
Nature
, vol.444
, pp. 171-178
-
-
Aury, J.-M.1
-
15
-
-
23044465906
-
Paralogs in polyploids: one for all and all for one?
-
Veitia R.A. Paralogs in polyploids: one for all and all for one?. Plant Cell 17 (2005) 4-11
-
(2005)
Plant Cell
, vol.17
, pp. 4-11
-
-
Veitia, R.A.1
-
16
-
-
0842285397
-
Eucaryotic genome evolution through the spontaneous duplication of large chromosomal segments
-
Koszul R., et al. Eucaryotic genome evolution through the spontaneous duplication of large chromosomal segments. EMBO J. 23 (2004) 234-243
-
(2004)
EMBO J.
, vol.23
, pp. 234-243
-
-
Koszul, R.1
-
17
-
-
38049150491
-
A protrait of copy-number polymorphism in Drosophila melanogaster
-
Dopman E.B., and Hartl D.L. A protrait of copy-number polymorphism in Drosophila melanogaster. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 19920-19925
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 19920-19925
-
-
Dopman, E.B.1
Hartl, D.L.2
-
18
-
-
33750938146
-
Preferential duplication in the sparse part of yeast protein interaction network
-
Li L., et al. Preferential duplication in the sparse part of yeast protein interaction network. Mol. Biol. Evol. 23 (2006) 2467-2473
-
(2006)
Mol. Biol. Evol.
, vol.23
, pp. 2467-2473
-
-
Li, L.1
-
19
-
-
34347353237
-
Copy-number variation and association studies of human disease
-
McCarroll S.A., and Altshuler D.M. Copy-number variation and association studies of human disease. Nat. Genet. 39 (2007) S37-S42
-
(2007)
Nat. Genet.
, vol.39
-
-
McCarroll, S.A.1
Altshuler, D.M.2
-
20
-
-
34347354302
-
Mutational and selective effects on copy-number variants in the human genome
-
Cooper G.M., et al. Mutational and selective effects on copy-number variants in the human genome. Nat. Genet. 39 (2007) S22-S29
-
(2007)
Nat. Genet.
, vol.39
-
-
Cooper, G.M.1
-
21
-
-
0031443249
-
Computer-based analysis of the binding steps in protein complex formation
-
Bray D., and Lay S. Computer-based analysis of the binding steps in protein complex formation. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 13493-13498
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 13493-13498
-
-
Bray, D.1
Lay, S.2
-
22
-
-
0025019539
-
Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway
-
Cole G.M., et al. Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway. Mol. Cell. Biol. 10 (1990) 510-517
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 510-517
-
-
Cole, G.M.1
-
23
-
-
0035942220
-
How activated receptors couple to G proteins
-
Hamm H.E. How activated receptors couple to G proteins. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 4819-4821
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 4819-4821
-
-
Hamm, H.E.1
-
24
-
-
0035338114
-
Subcellular localization of the Snf1 kinase is regulated by specific beta subunits and a novel glucose signaling mechanism
-
Vincent O., et al. Subcellular localization of the Snf1 kinase is regulated by specific beta subunits and a novel glucose signaling mechanism. Genes Dev. 15 (2001) 1104-1114
-
(2001)
Genes Dev.
, vol.15
, pp. 1104-1114
-
-
Vincent, O.1
-
25
-
-
38949158494
-
Protein under-wrapping causes dosage sensitivity and decreases gene duplicability
-
Liang H., et al. Protein under-wrapping causes dosage sensitivity and decreases gene duplicability. PLoS Genet. 4 (2008) e11
-
(2008)
PLoS Genet.
, vol.4
-
-
Liang, H.1
-
26
-
-
31544482407
-
Mapping pathways and phenotypes by systematic gene overexpression
-
Sopko R., et al. Mapping pathways and phenotypes by systematic gene overexpression. Mol. Cell 21 (2006) 319-330
-
(2006)
Mol. Cell
, vol.21
, pp. 319-330
-
-
Sopko, R.1
-
27
-
-
0842290925
-
Molecular evolution in large genetic networks: does connectivity equal constraint?
-
Hahn M.W., et al. Molecular evolution in large genetic networks: does connectivity equal constraint?. J. Mol. Evol. 58 (2004) 203-211
-
(2004)
J. Mol. Evol.
, vol.58
, pp. 203-211
-
-
Hahn, M.W.1
-
28
-
-
10744230485
-
Global mapping of the yeast genetic interaction network
-
Tong A.H., et al. Global mapping of the yeast genetic interaction network. Science 303 (2004) 808-813
-
(2004)
Science
, vol.303
, pp. 808-813
-
-
Tong, A.H.1
-
29
-
-
0035130371
-
Protein solubility and folding monitored in vivo by structural complementation of a genetic marker protein
-
Wigley W.C., et al. Protein solubility and folding monitored in vivo by structural complementation of a genetic marker protein. Nat. Biotechnol. 19 (2001) 131-136
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 131-136
-
-
Wigley, W.C.1
-
30
-
-
0036132659
-
Protection from free beta-tubulin by the beta-tubulin binding protein Rbl2p
-
Abruzzi K.C., et al. Protection from free beta-tubulin by the beta-tubulin binding protein Rbl2p. Mol. Cell. Biol. 22 (2002) 138-147
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 138-147
-
-
Abruzzi, K.C.1
-
31
-
-
0025063865
-
Regulation of tubulin levels and microtubule assembly in Saccharomyces cerevisiae: consequences of altered tubulin gene copy number
-
Katz W., et al. Regulation of tubulin levels and microtubule assembly in Saccharomyces cerevisiae: consequences of altered tubulin gene copy number. Mol. Cell. Biol. 10 (1990) 5286-5294
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 5286-5294
-
-
Katz, W.1
-
32
-
-
0344688414
-
53 kinase-dependent surveillance mechanism that regulates histone protein levels in S. cerevisiae
-
Gunjan A., et al. 53 kinase-dependent surveillance mechanism that regulates histone protein levels in S. cerevisiae. Cell 115 (2003) 537-549
-
(2003)
Cell
, vol.115
, pp. 537-549
-
-
Gunjan, A.1
-
33
-
-
33644858609
-
The emergence of regulated histone proteolysis
-
Gunjan A., et al. The emergence of regulated histone proteolysis. Curr. Opin. Genet. Dev. 16 (2006) 112-118
-
(2006)
Curr. Opin. Genet. Dev.
, vol.16
, pp. 112-118
-
-
Gunjan, A.1
-
34
-
-
0029965321
-
An RNA structure involved in feedback regulation of splicing and of translation is critical for biological fitness
-
Li B., et al. An RNA structure involved in feedback regulation of splicing and of translation is critical for biological fitness. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 1596-1600
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 1596-1600
-
-
Li, B.1
-
35
-
-
3343020085
-
Integrative analysis of cell cycle control in budding yeast
-
Chen K.C., et al. Integrative analysis of cell cycle control in budding yeast. Mol. Biol. Cell 15 (2004) 3841-3862
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3841-3862
-
-
Chen, K.C.1
-
36
-
-
0028574084
-
Trans-acting dosage effects on the expression of model gene systems in maize aneuploids
-
Guo M., and Birchler J.A. Trans-acting dosage effects on the expression of model gene systems in maize aneuploids. Science 266 (1994) 1999-2002
-
(1994)
Science
, vol.266
, pp. 1999-2002
-
-
Guo, M.1
Birchler, J.A.2
-
37
-
-
34250632677
-
The gene balance hypothesis: From classical genetics to modern genomics
-
Birchler J.A., and Veitia R.A. The gene balance hypothesis: From classical genetics to modern genomics. Plant Cell 19 (2007) 395-402
-
(2007)
Plant Cell
, vol.19
, pp. 395-402
-
-
Birchler, J.A.1
Veitia, R.A.2
-
38
-
-
0001099069
-
A study of enzyme activities in a dosage series of the long arm of chromosome one in maize
-
Birchler J.A. A study of enzyme activities in a dosage series of the long arm of chromosome one in maize. Genetics 92 (1979) 1211-1229
-
(1979)
Genetics
, vol.92
, pp. 1211-1229
-
-
Birchler, J.A.1
-
39
-
-
0000016658
-
Modulation of protein levels in chromosomal dosage series of maize: The biochemical basis of aneuploid syndromes
-
Birchler J.A., and Newton K.J. Modulation of protein levels in chromosomal dosage series of maize: The biochemical basis of aneuploid syndromes. Genetics 99 (1981) 247-266
-
(1981)
Genetics
, vol.99
, pp. 247-266
-
-
Birchler, J.A.1
Newton, K.J.2
-
40
-
-
0027204303
-
Dosage dependent modifiers of white alleles in Drosophila melanogaster
-
Sabl J.F., and Birchler J.A. Dosage dependent modifiers of white alleles in Drosophila melanogaster. Genet. Res. 62 (1993) 15-22
-
(1993)
Genet. Res.
, vol.62
, pp. 15-22
-
-
Sabl, J.F.1
Birchler, J.A.2
-
41
-
-
0026609125
-
Expression of cis-regulatory mutants of the white locus in metafemales of Drosophila melanogaster
-
Birchler J.A. Expression of cis-regulatory mutants of the white locus in metafemales of Drosophila melanogaster. Gen. Res. 59 (1992) 11-18
-
(1992)
Gen. Res.
, vol.59
, pp. 11-18
-
-
Birchler, J.A.1
-
42
-
-
0025949334
-
A trans-acting regulatory gene that inversely affects the expression of the white, brown and scarlet loci in Drosophila melanogaster
-
Rabinow L., et al. A trans-acting regulatory gene that inversely affects the expression of the white, brown and scarlet loci in Drosophila melanogaster. Genetics 129 (1991) 463-480
-
(1991)
Genetics
, vol.129
, pp. 463-480
-
-
Rabinow, L.1
-
43
-
-
33846394799
-
Gene regulation by chromatin structure: Paradigms established in Drosophila melanogaster
-
Schulze S.R., and Wallrath L.L. Gene regulation by chromatin structure: Paradigms established in Drosophila melanogaster. Annu. Rev. Entomol. 52 (2007) 171-192
-
(2007)
Annu. Rev. Entomol.
, vol.52
, pp. 171-192
-
-
Schulze, S.R.1
Wallrath, L.L.2
-
44
-
-
34548264230
-
Classification of human chromosome 21 gene-expression variations in Down Syndrome: Impact on disease phenotypes
-
Aït Yahya-Graison E., et al. Classification of human chromosome 21 gene-expression variations in Down Syndrome: Impact on disease phenotypes. Am. J. Hum. Genet. 81 (2007) 475-491
-
(2007)
Am. J. Hum. Genet.
, vol.81
, pp. 475-491
-
-
Aït Yahya-Graison, E.1
-
45
-
-
3543097554
-
Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome
-
Lyle R., et al. Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome. Genome Res. 14 (2004) 1268-1274
-
(2004)
Genome Res.
, vol.14
, pp. 1268-1274
-
-
Lyle, R.1
-
46
-
-
3543110316
-
Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome
-
Kahlem P., et al. Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome. Genome Res. 14 (2004) 1258-1267
-
(2004)
Genome Res.
, vol.14
, pp. 1258-1267
-
-
Kahlem, P.1
-
47
-
-
39049105158
-
Specific transcriptional changes in human fetuses with autosomal trisomies
-
Altug-Teber O., et al. Specific transcriptional changes in human fetuses with autosomal trisomies. Cytogenet. Genome Res. 119 (2007) 171-184
-
(2007)
Cytogenet. Genome Res.
, vol.119
, pp. 171-184
-
-
Altug-Teber, O.1
-
48
-
-
15244350824
-
Dosage balance in gene regulation: biological implications
-
Birchler J.A., et al. Dosage balance in gene regulation: biological implications. Trends Genet. 21 (2005) 219-226
-
(2005)
Trends Genet.
, vol.21
, pp. 219-226
-
-
Birchler, J.A.1
-
49
-
-
0038104857
-
Genomic gene clustering analysis of pathways in eukaryotes
-
Lee J.M., and Sonnhammer E.L. Genomic gene clustering analysis of pathways in eukaryotes. Genome Res. 13 (2003) 875-882
-
(2003)
Genome Res.
, vol.13
, pp. 875-882
-
-
Lee, J.M.1
Sonnhammer, E.L.2
-
50
-
-
4644358610
-
Genes encoding subunits of stable complexes are clustered on the yeast chromosomes: an interpretation from a dosage balance perspective
-
Teichmann S.A., and Veitia R.A. Genes encoding subunits of stable complexes are clustered on the yeast chromosomes: an interpretation from a dosage balance perspective. Genetics 167 (2004) 2121-2125
-
(2004)
Genetics
, vol.167
, pp. 2121-2125
-
-
Teichmann, S.A.1
Veitia, R.A.2
-
51
-
-
29444455049
-
Dosage compensation of the active X chromosome in mammals
-
Nguyen D.K., and Disteche C.M. Dosage compensation of the active X chromosome in mammals. Nat. Genet. 38 (2006) 47-53
-
(2006)
Nat. Genet.
, vol.38
, pp. 47-53
-
-
Nguyen, D.K.1
Disteche, C.M.2
-
52
-
-
38749117957
-
Dosage compensation in the mouse balances up-regulation and silencing of X-linked genes
-
Lin H., et al. Dosage compensation in the mouse balances up-regulation and silencing of X-linked genes. PLoS Biol. 5 (2007) e326
-
(2007)
PLoS Biol.
, vol.5
-
-
Lin, H.1
-
53
-
-
33847020017
-
Global analysis of X-chromosome dosage compensation
-
Gupta V., et al. Global analysis of X-chromosome dosage compensation. J. Biol. 5 (2006) 3
-
(2006)
J. Biol.
, vol.5
, pp. 3
-
-
Gupta, V.1
-
54
-
-
0346460960
-
Paucity of genes on the Drosophila X chromosome showing male-biased expression
-
Parisi M., et al. Paucity of genes on the Drosophila X chromosome showing male-biased expression. Science 299 (2003) 697-700
-
(2003)
Science
, vol.299
, pp. 697-700
-
-
Parisi, M.1
-
55
-
-
33745069974
-
Commonalities in compensation
-
Birchler J.A., et al. Commonalities in compensation. Bioessays 28 (2006) 565-568
-
(2006)
Bioessays
, vol.28
, pp. 565-568
-
-
Birchler, J.A.1
-
56
-
-
33845768982
-
Dosage compensation: the beginning and end of generalization
-
Straub T., and Becker P.B. Dosage compensation: the beginning and end of generalization. Nat. Rev. Genet. 8 (2007) 47-57
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 47-57
-
-
Straub, T.1
Becker, P.B.2
-
57
-
-
33748922985
-
20S proteasomes and protein degradation 'by default'
-
Asher G., et al. 20S proteasomes and protein degradation 'by default'. Bioessays 28 (2006) 844-849
-
(2006)
Bioessays
, vol.28
, pp. 844-849
-
-
Asher, G.1
-
58
-
-
22144443131
-
Nonlinear protein degradation and the function of genetic circuits
-
Buchler N.E., et al. Nonlinear protein degradation and the function of genetic circuits. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 9559-9564
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 9559-9564
-
-
Buchler, N.E.1
-
59
-
-
41149125082
-
Structural disorder serves as a weak signal for intracellular protein degradation
-
Tompa P., et al. Structural disorder serves as a weak signal for intracellular protein degradation. Proteins 71 (2008) 903-909
-
(2008)
Proteins
, vol.71
, pp. 903-909
-
-
Tompa, P.1
-
60
-
-
38149063767
-
Structural disorder promotes assembly of protein complexes
-
Hegyi H., et al. Structural disorder promotes assembly of protein complexes. BMC Struct. Biol. 7 (2007) 65
-
(2007)
BMC Struct. Biol.
, vol.7
, pp. 65
-
-
Hegyi, H.1
-
61
-
-
40149087235
-
Data and theory point to mainly additive genetic variance for complex traits
-
Hill W.G., et al. Data and theory point to mainly additive genetic variance for complex traits. PLoS Genet. 4 (2008) e1000008
-
(2008)
PLoS Genet.
, vol.4
-
-
Hill, W.G.1
|