Control of cholesterol access to cytochrome P450scc in rat adrenal cells mediated by regulation of the steroidogenic acute regulatory protein

Steroids

Volumn 62, Issue 1, 1997, Pages 10-20

  Kim, Young Cheul ^a   Ariyoshi, Noritaka ^a   Artemenko, Irina ^a   Elliott, Mary E ^a   Bhattacharyya, Kalyan K ^a   Jefcoate, Colin R ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

acute response; adrenal cell; cholesterol transport; steroidogenesis

Indexed keywords

CHOLESTEROL; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYCLIC AMP; PREGNENOLONE; REGULATOR PROTEIN;

ADRENAL CORTEX CELL; ANIMAL CELL; CATTLE; CHOLESTEROL TRANSPORT; CONFERENCE PAPER; CONTROLLED STUDY; GLOMERULOSA CELL; HORMONAL REGULATION; NONHUMAN; RAT; STEROIDOGENESIS; TRANSLATION REGULATION; ZONA FASCICULATA;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0031014607     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(96)00153-5     Document Type: Conference Paper

References (72)

1. Stone D, Hechter O (1954). Studies on ACTH action in perfused bovine adrenals: site of action of ACTH in corticosteroidogenesis. Arch Biochem Biophys 51:457-469.
2. Garren LD, Gill GN, Masui H, Walton GM (1971). On the mechanism of action of ACTH. Recent Prog Horm Res 27:433-478.
3. Crivello JF, Jefcoate CR (1978). Mechanism of corticotropin action in rat adrenal cells. 1. Effect of inhibitors of protein synthesis and of microfilament formation on corticosterone synthesis. Biochim Biophys Acta 542:315-329.
4. Simpson ER, Jefcoate CR, Brownie AC, Boyd GS (1972). The effect of either stress anaesthesis on cholesterol side-chain cleavage and cytochrome P450 in rat adrenal mitochondria. Eur J Biochem 28:443-450.
5. Brownie AC, Alfano J, Jefcoate CR, Beinert H, Orme-Johnson WH (1973). Effect of ACTH on adrenal mitochondrial cytochrome P450 in rat. Ann NY Acad Sci 212:344-360.
6. Jefcoate CR, Simpson ER, Boyd GS (1974). Spectral properties of rat drenal mitochondrial cytochrome P450. Eur J Biochem 42:539-551.
7. Jefcoate CR, Orme-Johnson WH (1975). Cytochrome P450 of adrenal mitochondria: in vitro and in vivo changes in spin state. J Biol Chem 250:4671-4677.
8. Jefcoate CR, Orme-Johnson WH, Beinert H (1976). Cytochrome P-450 of bovine adrenal mitochondria: ligand binding to two forms resolved by EPR spectroscopy. J Biol Chem 251:3706-3715.
9. Farkash Y, Timberg R, Orly J (1986). Preparation of antiserum to rat cytochrome P-450 cholesterol side chain cleavage, and its use for ultrastructural localization of the immunoreactive enzyme by protein A-gold technique. Endocrinology 118:1353-1365.
10. Simpson ER, McCarthy JL, Peterson JA (1979). Evidence that the cycloheximide-sensitive site of ACTH action is in the mitochondrion. J Biol Chem 253:3135-3139.
11. scc in rat adrenal gland. Proc Natl Acad Sci USA 80: 702-706.
12. Ohno Y, Yanagibashi K, Yonezawa Y, Ishiwatari S, Matsuba M (1983). A possible role of "steroidogenic factor" in the corticoidogenic response to ACTH: effect of ACTH, cycloheximide and aminoglutethimide on the content of cholesterol in the outer and inner mitochondrial membrane of rat adrenal cortex. Endocrinol Jpn 30:335-338.
13. Gwynne JT, Strauss JF III (1982). The role of lipoproteins in steroidogenesis and cholesterol metabolism in steroidogenic glands. Endocr Rev 3:299-329.
14. Ghosh DK, Dunham WR, Sands RH, Menon MJ (1987). Regulation of cholesterol side-chain cleavage enzyme activity by gonadotropin in rat corpus luteum. Endocrinology 121:21-27.
15. Jamal Z, Suffolk RA, Boyd GS, Suckling KE (1985). Metabolism of cholesteryl ester in monolayers of bovine adrenal cortical cells. Effect of an inhibitor of acyl-CoA: cholesterol acyltransferase. Biochim Biophys Acta 834:230-237.
16. Yeaman SJ (1990). Hormone-sensitive lipase - a multi-purpose enzyme in lipid metabolism. Biochim Biophys Acta 1052:128-152.
17. DiBartolomeis MJ, Jefcoate CR (1984). Characterization of the acute stimulation of steroidogenesis in primary bovine adrenal cortical cell cultures. J Biol Chem 259:10159-10167.
18. Almahbobi G, Hall PF (1990). The role of intermediate filaments in adrenal steroidogenesis. J Cell Sci 97:679-687.
19. Murata M, Peränen J, Schreiner R, Wieland F, Kurzchalia T, Simons K (1995). VIP21/caveolin is a cholesterol-binding protein. Proc Natl Acad Sci USA 92:10339-10343.
20. Hall PF (1995). The roles of microfilaments and intermediate filaments in the regulation of steroid synthesis. J Steroid Biochem Mol Biol 55:601-605.
21. 2: further evidence for its role in adrenal steroidogenesis. Endocr Res 12:351-360.
22. Freeman DA (1989). Plasma membrane cholesterol: removal and insertion into the membrane and utilization as a substrate for steroidogenesis. Endocrinology 124:2527-2535.
23. Arthur JR, Mason JI (1976). Effect of calcium ions on metabolism of exogenous cholesterol by rat adrenal mitochondria. FEBS Lett 66:206-209.
24. Krueger RJ, Orme-Johnson NR (1983). Acute adrenocorticortropic hormone stimulation of adrenal corticosteroidogenesis. J Biol Chem 258:10159-10167.
25. Alberta JA, Epstein LF, Pon LA, Orme-Johnson NR (1989). Mitochondrial localization of a phosphoprotein that rapidly accumulates in adrenal cortex cells exposed to adrenocorticotropic hormone or to cAMP. J Biol Chem 264:2368-2372.
26. Epstein LF, Orme-Johnson NR (1991). Regulation of steroid hormone biosynthesis: identification of precursors of a phosphoprotein targeted to the mitochondrion in stimulated rat adrenal cortex cells. J Biol Chem 266:19739-19745.
27. 2C rat Leydig tumor and stimulated nonconstitutive steroid-producing MA-10 mouse Leydig tumor cells. Endocrinology 128:1918-1926.
28. Stocco DM, Clark BJ (1993). The requirement of phosphorylation on a threonine residue in the acute regulation of steroidogenesis in MA-10 mouse Leydig tumor cells. J Steroid Biochem Mol Biol 46:337-347.
29. Stocco DM, Sodeman TC (1991). The 30-kDa mitochondrial proteins induced by hormone stimulation in MA-10 mouse Leydig tumor cells are processed from larger precursors. J Biol Chem 266: 19731-19738.
30. Clark BJ, Wells J, King SR, Stocco DM (1994). The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells: characterization of the steroidogenic acute regulatory protein (StAR). J Biol Chem 269:28314-28322.
31. Clark BJ, Soo S-C, Caron KM, Ikeda Y, Parker KL, Stocco DM (1995). Hormonal and developmental regulation of the steroidogenic acute regulatory protein. Mol Endocrinol 9:1346-1355.
32. Stocco DM, Clark BJ (1996). Role of the steroidogenic acute regulatory protein (StAR) in steroidogenesis. Biochem Pharmacol 51: 197-205.
33. Krueger KE, Papadopoulos V (1990). Peripheral-type benzodiazepine receptors mediate translocation of cholesterol from outer to inner mitochondrial membranes in adrenocortical cells. J Biol Chem 265:15015-15022.
34. Papadopoulos V, Nowzari FB, Krueger VE (1991). Hormone-stimulated steroidogenesis is coupled to mitochondrial benzodiazepine receptors. J Biol Chem 266:3682-3687.
35. Garnier M, Dimchev AB, Boujrad N, Price JM, Musto NA, Papadopoulos V (1994). In vitro reconstitution of a functional peripheral-type benzodiazepine receptor from mouse Leydig tumor cells. Mol Pharmacol 45:201-211.
36. Garnier M, Boujrad N, Ogwuegbu SO, Hudson JR Jr., Papdopoulos V (1994). The polypeptide diazepam-binding inhibitor and a higher affinity mitochondrial peripheral-type benzodiazepine receptor sustain constitutive steroidogenesis in the R2C Leydig tumor cell line. J Biol Chem 269:22105-22112.
37. Knudsen J, Nielsen M (1990). Diazepam-binding inhibitor: a neuropeptide and/or an acyl-CoA ester binding protein. Biochem J 265: 927-928.
38. Boujrad N, Hudson JR Jr., Papadopoulos V (1993). Inhibition of hormone-stimulated steroidogenesis in cultured Leydig tumor cells by a cholesterol-linked phosphorothioate oligodeoxynucleotide antisense to diazepam binding inhibitor. Proc Natl Acad Sci USA 90:5728-5733.
39. Papadopoulos V, Brown AS (1995). Role of the peripheral-type benzodiazepine receptor and the polypeptide diazepam binding inhibitor in steroidogenesis. J Steroid Biochem Mol Biol 53:103-110.
40. Boujrad N, Gaillard JL, Garnier M, Papadopoulos V (1994). Acute action of choriogonadotropin on Leydig tumor cells: induction of a high affinity benzodiazepine-binding site related to steroid biosynthesis. Endocrinology 135:1576-1583.
41. Rojo M, Hovius R, Demel RA, Nicolay K, Wallimann T (1991). Mitochondrial creatine kinase mediates cotact formation between mitochondrial membranes. J Biol Chem 266:20290-20295.
42. Jefcoate CR, McNamara BC, Artemenko I, Yamazaki T (1992). Regulation of cholesterol movement to mitochondrial cytochrome P450scc in steroid hormone synthesis. J Steroid Biochem Mol Biol 43:751-767.
43. Stevens VL, Tribble DL, Lambeth JD (1985). Regulation of mitochondrial compartment volumes in rat adrenal cortex by ether stress. Arch Biochem Biophys 242:324-327.
44. Servetnick DA, Brasaemle DL, Gruia-Gray J, Kimmel A, Wolff J, Londos C (1995). Perilipins are associated with cholesteryl ester droplets in steroidogenic adrenal cortical and Leydig cells. J Biol Chem 270:16970-16973.
45. Lin D, Sugawara T, Strauss JF, Clark BJ, Stocco DM, Saenger P, Rogol A, Miller WL (1995). Role of steroidogenenic acute regulatory protein in adrenal and gonadal steroidogenesis. Science 267: 1828-1831.
46. Elliott ME, Goodfriend TL, Jefcoate CR (1993). Bovine adrenal glomerulosa and fasciculata cells exhibit 28.5-kilodalton proteins sensitive to angiotensin, other agonists, and atrial natriuretic peptide. Endocrinology 133:1669-1677.
47. Brake PB, Jeffcoate CR (1995). Regulation of cytochrome P4501B1 in cultured rat adrenocortical cells by cyclic adenosine 3′,5′-monophosphate and 2,3,7,8-tetrachlorodibenzo-p-dioxin. Endocrinology 136:5034-5041.
48. Bhattacharyya KK, Brake PB, Eltom SE, Otto SA, Jefcoate CR (1995). Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYB 1B1: demonstration of a unique tissue-specific pattern of hormonal and arylhydrocarbon receptor-linked regulation. J Biol Chem 270:11595-11602.
49. Buckingham L, Duncan J (1983). Approximate dimensions of membrane lesions produced by streptolysin S and streptolysin. O. Biochim Biophys Acta 29:115-122.
50. Rothman JE (1992). Reconstitution of intracellular transport. Methods Enzymol 219:234-239.
51. 2+ and structure in platelets contacting synthetic substrates. Cells Mater 2:299-308.
52. Elliott ME, Goodfriend TL (1986). Inhibition of aldosterone synthesis by atrial natriuretic factor. Fed Proc 45:2376-2381.
53. Hartigan JA, Green EG, Mortensen RM, Menachery A, Williams GH, Orme-Johnson NR (1995). Comparison of protein phosphorylation patterns produced in adrenal cells by activation of cAMP-dependent protein kinase and Ca-dependent protein kinase. J Steroid Biochem Mol Biol 53:95-101.
54. Mittre H, Aunai P, Benhaim A, Leymarie P (1990). Acute stimulation by lutropin of mitochondrial protein synthesis in small luteal cells. Eur J Biochem 187:721-726.
55. Xu T, Bowman EP, Glass DV, Lambeth JD (1991). Stimulation of adrenal mitochondrial cholesterol side-chain cleavage by GTP, steroidogenesis activator polypeptide (SAP), and sterol carrier protein. J Biol Chem 266:6801-6807.
56. Arthur JR, Boyd GS (1976). The effect of inhibitors of protein synthesis on cholesterol side-chain cleavage in the mitochondria of luteinized rat ovaries. Eur J Biochem 49:117-127.
57. 2+ and by GTP. Mol Cell Endocrinol 107:1-8.
58. Abraham GE, Buster JE, Kyle FW, Corrales PC, Teller RC (1973). Radioimmunoassay of plasma pregnenolone, 17-hydroxypregnenolone and dehydroepiandrosterone under various physiological conditions. J Clin Endocrinol Metab 37:140-144.
59. McNamara BC, Jefcoate CR (1990). Heterogeneous pools of cholesterol side-chain cleavage activity in adrenal mitochondria from ACTH-treated rats: differential response to different reducing precursors. Mol Cell Endocrinol 73:123-134.
60. Mikami K, Omura M, Tamura Y, Yoshida S (1990). Possible site of action of 5-hydroperoxyeicosatetraenoic acid derived from arachidonic acid in ACTH-stimulated steroidogenesis in rat adrenal glands. J Endocrinol 125:89-96.
61. Dix CJ, Habberfield AD, Sullivan MH, Cooke BA (1985). Evidence for the involvement of lipoxygenase products in steroidogenesis. Biochem Soc Trans B 60-63.
62. McNamara BC, Jefcoate CR (1990). Heterogenous pools of cholesterol side-chain cleavage activity in adrenal mitochondria from adrenocorticotropic hormone-treated rats: reconstitution of the isocitrate response with succinate and low concentrations of isocitrate. Arch Bichem Biophys 283:464-471.
63. Kuznetsov AV, Khuchua ZA, Vassil'eva EV, Medved'eva NV, Saks VA (1989). Heart mitochondrial creatine kinase revisited: the outer mitochondrial membrane is not important for coupling of phosphocreatine production to oxidative phosphorylation. Arch Biochem Biophys 268:176-190.
64. King SR, Ronen-Fuhrmann T, Timberg R, Clark BJ, Orly J, Stocco DM (1995). Steroid production after in vitro transcription, translation, and mitochondrial processing of protein products of complementary deoxyribonucleic acid for steroidogenic acute regulatory protein. Endocrinology 136:5165-5176.
65. Keren-Tal I, Suh B-S, Dantes A, Lindner S, Oren M, Amsterdam A (1995). Involvement of p53 expression in cAMP-mediated apoptosis in immortalized granulosa cells. Exp Cell Res 218:283-295.
66. Sugawara T, Lin D, Holt JA, Martin KO, Javitt NB, Miller WL, Strauss JF (1995). Structure of the human steroidogenic acute regulatory protein (StAR) gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase activity. Biochemistry 34:12506-12512.
67. Jackson RJ, Standard N (1990). Do the poly(A) tail and 3′ untranslated region control mRNA translation? Cell 62:15-24.
68. Jackson R (1993). Cytoplasmic regulation of mRNA function: the importance of the 3′ untranslated region. Cell 74:9-14.
69. Igarashi Y, Kimura T (1984). Adrenocorticotropic hormone-mediated changes in rat adrenal mitochondrial phospholipids. J Biol Chem 259:10745-10753.
70. scc. Regulation of intramitochondrial cholesterol transfer. Mol Cell Endocrinol 53:87-101.
71. Randazzo PA, Northup JK, Kahn RA (1991). Activation of a small GTP-binding protein by nucleoside diphophate kinase. Science 254: 850-853.
72. Killian JA, deKruijff B (1986). The influence of proteins and peptides on the phase properties of lipids. Chem Phys Lipids 40:259-284.