NMR-based mapping of disulfide bridges in cysteine-rich peptides: Application to the μ-conotoxin SxIIIA

Journal of the American Chemical Society

Volumn 130, Issue 43, 2008, Pages 14280-14286

  Walewska, Aleksandra ^a,c   Skalicky, Jack J ^b   Davis, Darrell R ^a   Zhang, Min Min ^a   Lopez Vera, Estuardo ^a,d   Watkins, Maren ^b   Han, Tiffany S ^a   Yoshikami, Doju ^a   Olivera, Baldomero M ^a   Bulaj, Grzegorz ^a  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF GDA SK   (Poland)

^d UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BRIDGES; CONFORMAL MAPPING; ISOTOPES; NUCLEAR MAGNETIC RESONANCE; PEPTIDES; PROTEINS; RESONANCE; SODIUM; SYNTHESIS (CHEMICAL);

BIOACTIVE PEPTIDES; CHEMICAL SYNTHESES; CHEMICALLY SYNTHESIZED; CONOTOXINS; CYS RESIDUES; CYSTEINE RESIDUES; DISULFIDE BRIDGES; EFFICIENT; FOLDING METHODS; FUNCTIONAL CHARACTERIZATIONS; NATURAL PRODUCTS; NMR SPECTROSCOPIES; OXIDATION PRODUCTS; OXIDATIVE FOLDING; RESONANCE ASSIGNMENTS; SODIUM CHANNELS;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

CONOTOXIN; CYSTEINE PROTEINASE; DISULFIDE; MU CONOTOXIN SXIIIA; SODIUM CHANNEL; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; NITROGEN NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE; PEPTIDE MAPPING; PROTEIN FOLDING; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; CONOTOXINS; CONUS SNAIL; CYSTEINE; DISULFIDES; MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION-REDUCTION; PEPTIDES, CYCLIC; PROTEIN FOLDING; REFERENCE STANDARDS; TIME FACTORS;

EID: 54849440134     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja804303p     Document Type: Article

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