A novel M-superfamily conotoxin with a unique motif from Conus vexillum

Peptides

Volumn 27, Issue 4, 2006, Pages 682-689

  Jiang, Hui ^a,b   Wang, Cheng Zhong ^a   Xu, Chen Qi ^a   Fan, Chong Xu ^b   Dai, Xian Dong ^b   Chen, Ji Sheng ^b   Chi, Cheng Wu ^a,c  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b Research Institute of Pharmaceutical Chemistry   (China)

^c TONGJI UNIVERSITY   (China)

Author keywords

cDNA cloning; Conotoxin; Conus vexillum; Electrophysiology; Refolding

Indexed keywords

AMINO ACID; CONOTOXIN; ION CHANNEL; SNAIL VENOM; UNCLASSIFIED DRUG; VX2 CONOTOXIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DISULFIDE BOND; MALE; MOLECULAR CLONING; MOUSE; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PURIFICATION; SNAIL; SYNTHESIS; TOXIN ANALYSIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; CONOTOXINS; CONUS SNAIL; DNA, COMPLEMENTARY; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA; CONUS VEXILLUM; GASTROPODA; MOLLUSCA;

EID: 33645395545     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2005.08.004     Document Type: Article

References (35)

1. D. Alonso, Z. Khalil, and B.G. Livett Drugs from the sea: conotoxins as drug leads for neuropathic pain and other neurologicalconditions Mini Rev Med Chem 3 2003 785 787
2. S.F. Altschul, T.L. Madden, A.A. Schaffer, J. Zhang, Z. Zhang, and W. Miller Gapped BLAST and PSI-BLAST: a new generation of protein database search programs Nucleic Acids Res 25 1997 3389 3402
3. P.K. Bandyopadhyay, C.J. Colledge, C.S. Walker, L.M. Zhou, D.R. Hillyard, and B.M. Olivera Conantokin-G precursor and its role in γ-carboxylation by a vitamin K-dependent carboxylase from a Conus snail J Biol Chem 273 1998 5447 5450
4. + currents in isolated dorsal unpaired median neurons of Locusta migratoria and effect of the α-like scorpion toxin BmK M1 J Insect Physiol 49 2003 171 182
5. O. Buczek, B.M. Olivera, and G. Bulaj Propeptide does not act as an intramolecular chaperone but facilitates protein disulfide isomerase-assisted folding of a conotoxin precursor Biochemistry 43 2004 1093 1101
6. C.J. Colledge, J.P. Hunsperger, J.S. Imperial, and D.R. Hillyard Precursor structure of ω-conotoxin GVIA determined from a cDNA clone Toxicon 30 1992 1111 1116
7. S.G. Conticello, Y. Gilad, N. Avidan, E. Ben-Asher, Z. Levy, and M. Fainzilber Mechanisms for evolving hypervariability: the case of conopeptides Mol Biol Evol 18 2001 120 131
8. S.G. Conticello, N.D. Kowalsman, C. Jacobsen, G. Yudkovsky, K. Sato, and Z. Elazar The prodomain of a secreted hydrophobic miniprotein facilitates its export from the endoplasmic reticulum by hitchhiking on sorting receptors J Biol Chem 278 2003 26311 26314
9. L.J. Cruz, W.R. Gray, B.M. Olivera, R.D. Zeikus, L.K. Doju, and D. Yoshikami Conus geographus toxins that discriminate between neuronal and muscle sodium channels J Biol Chem 260 1985 9280 9288
10. M. Dietrich Toxicity in animals: trends in evolution? Toxicon 39 2001 87 96
11. D.J. Espiritu, M. Watkins, V. Dia-Monje, G.E. Cartier, L.J. Cruz, and B.M. Olivera Venomous cone snails: molecular phylogeny and the generation of toxin diversity Toxicon 39 2001 1899 1916
12. C.X. Fan, X.K. Chen, C. Zhang, L.X. Wang, K.L. Duan, and L.L. He A novel conotoxin from Conus betulinus, κ-BtX, unique in cysteine pattern and in function as a specific BK channel modulator J Biol Chem 278 2003 12624 12633
13. + channels J Biol Chem 278 2003 2177 2183
14. O.P. Hamill, A. Marty, E. Neher, B. Sakmann, and F.J. Sigworth Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches Pflugers Arch 391 1981 85 100
15. R.M. Jones, and G. Bulaj Conotoxins - new vistas for peptide therapeutics Curr Pharm Des 6 2000 1249 1285
16. J.M. McIntosh, B.M. Olivera, and L.J. Cruz Conus peptides as probes for ion channels Meth Enzymol 294 1999 605 624
17. J.M. McIntosh, A. Hasson, M.E. Spira, W.R. Gray, W. Li, and M. Marsh A new family of conotoxins that blocks voltage-gated sodium channels J Biol Chem 270 1995 16796 16802
18. J.M. McIntosh, A.D. Santos, and B.M. Olivera Conus peptides targeted to specific nicotinic acetylcholine receptor subtypes Annu Rev Biochem 68 1999 59 88
19. R.A. Myers, L.J. Cruz, J.E. Rivier, and B.M. Olivera Conus peptides as chemical probes for receptors and ion channels Chem Rev 93 1993 1923 1936
20. B.M. Oliveraa, and L.J. Cruzab Conotoxins, in retrospect Toxicon 39 2001 7 14
21. G.P. Corpuz, R.B. Jacobsen, E.C. Jimenez, M. Watkins, C. Walker, and C. Colledge Definition of the M-conotoxin superfamily: characterization of novel peptides from molluscivorous Conus venoms Biochemistry 44 2005 8176 8186
22. B.M. Olivera, J. Rivier, C. Clark, C.A. Ramilo, G.P. Corpuz, and F.C. Abogadie Diversity of Conus neuropeptides Science 249 1999 257 263
23. B.M. Olivera, C. Walker, G.E. Cartier, D. Hooper, A.D. Santos, and R. Schoenfeld Speciation of cone snails and interspecific hyperdivergence of their venom peptides Ann N Y Acad Sci 870 1999 223 237
24. C.A. Ramilo, G.C. Zafaralla, L. Nadasdi, L.G. Hammerland, D. Yoshikami, and W.R. Gray Novel α- and ω-conotoxins from Conus striatus venom Biochemistry 31 1992 9919 9926
25. G.S. Shen, R.T. Layer, and R.T. McCabe Conopeptides: from deadly venoms to novel therapeutics Drug Discov Today 5 2000 98 106
26. K.J. Shon, M. Grilley, R. Jacobsen, G.E. Cartier, C. Hopkins, and W.R. Gray A noncompetitive peptide inhibitor of the nicotinic acetylcholine receptor from Conus purpurascens venom Biochemistry 36 1997 9581 9587
27. + channel subtypes J Neurosci 18 1998 4473 4481
28. H. Terlau, and B.M. Olivera Conus venoms: a rich source of novel ion channel-targeted peptides Physiol Rev 84 2004 41 68
29. R.M. Van Wagone, R.B. Jacobsen, B.M. Olivera, and C.M. Ireland Characterization and three-dimensional structure determination of ψ-conotoxin PIIIF, a novel noncompetitive antagonist of nicotinic acetylcholine receptors Biochemistry 42 2003 6353 6362
30. C.Z. Wang, H. Jiang, Z.L. Ou, J.S. Chen, and C.W. Chi cDNA cloning of two A-superfamily conotoxins from Conus striatus Toxicon 42 2003 613 619
31. P.J. West, G. Bulaj, J.E. Garrett, B.M. Olivera, and D. Yoshikami μ-Conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons Biochemistry 41 2002 15388 15393
32. 2+ tactivated potassium channels from the scorpion Buthus martensi Karsch FEBS Lett 452 1999 360 364
33. J.J. Wu, L. Dai, Z.D. Lan, and C.W. Chi The gene cloning and sequencing of Bm-12, a chlorotoxin-like peptide from the scorpion Buthus martensi Karsch Toxicon 38 2000 661 668
34. + channel blocker purified from the Asian scorpion Buthus martensi Karsch J Biol Chem 279 2004 34562 34569
35. L.Z. Yan, and J.P. Mayer Use of trichloroacetimidate linker in solid-phase peptide synthesis J Org Chem 68 2003 1161 1162